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Base editing boosts hemoglobin in sickle cell disease 碱基编辑增加镰状细胞病中的血红蛋白
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02517-4
{"title":"Base editing boosts hemoglobin in sickle cell disease","authors":"","doi":"10.1038/s41587-024-02517-4","DOIUrl":"10.1038/s41587-024-02517-4","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1759-1759"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discovering the crucial function of long noncoding RNAs 发现长链非编码rna的关键功能
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02509-4
Iris Marchal
{"title":"Discovering the crucial function of long noncoding RNAs","authors":"Iris Marchal","doi":"10.1038/s41587-024-02509-4","DOIUrl":"10.1038/s41587-024-02509-4","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1793-1793"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An update on Cuban biotech 古巴生物技术的最新进展
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02458-y
José A. Buxadó, Miladys Limonta Fernández, Gerardo E. Guillén Nieto, Raimundo Ubieta Gómez, Marta Ayala Ávila
{"title":"An update on Cuban biotech","authors":"José A. Buxadó, Miladys Limonta Fernández, Gerardo E. Guillén Nieto, Raimundo Ubieta Gómez, Marta Ayala Ávila","doi":"10.1038/s41587-024-02458-y","DOIUrl":"10.1038/s41587-024-02458-y","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1768-1770"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evo learns biological complexity from the molecular to genome scale 超能力从分子到基因组级别学习生物复杂性
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02514-7
Iris Marchal
{"title":"Evo learns biological complexity from the molecular to genome scale","authors":"Iris Marchal","doi":"10.1038/s41587-024-02514-7","DOIUrl":"10.1038/s41587-024-02514-7","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1793-1793"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant bling: cellulose that sparkles 植物光泽：会发光的纤维素
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02507-6
Michael Francisco
{"title":"Plant bling: cellulose that sparkles","authors":"Michael Francisco","doi":"10.1038/s41587-024-02507-6","DOIUrl":"10.1038/s41587-024-02507-6","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1762-1762"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41587-024-02507-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stem cells 干细胞
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02496-6
{"title":"Stem cells","authors":"","doi":"10.1038/s41587-024-02496-6","DOIUrl":"10.1038/s41587-024-02496-6","url":null,"abstract":"Recent patents relating to compositions, methods of preparation and use of stem cells.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1792-1792"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CRISPR unlocks a sweet tomato that keeps its size CRISPR解锁了保持其大小的甜番茄
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02510-x
Iris Marchal
{"title":"CRISPR unlocks a sweet tomato that keeps its size","authors":"Iris Marchal","doi":"10.1038/s41587-024-02510-x","DOIUrl":"10.1038/s41587-024-02510-x","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1793-1793"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
People 人
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02501-y
{"title":"People","authors":"","doi":"10.1038/s41587-024-02501-y","DOIUrl":"10.1038/s41587-024-02501-y","url":null,"abstract":"Recent moves of note in and around the biotech and pharma industries.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1926-1926"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using artificial intelligence to develop gene therapy for the lungs 利用人工智能开发肺部基因疗法
IF 46.9 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02491-x
{"title":"Using artificial intelligence to develop gene therapy for the lungs","authors":"","doi":"10.1038/s41587-024-02491-x","DOIUrl":"https://doi.org/10.1038/s41587-024-02491-x","url":null,"abstract":"Gene therapy in the lungs could treat a range of devastating illnesses, but lack of safe and efficient delivery has held back the field. Here, in silico screening of millions of lipid nanoparticles (LNPs) yielded several chemically novel and highly potent LNPs for pulmonary gene therapy.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"19 1","pages":""},"PeriodicalIF":46.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging machine learning and big data techniques to map the global patent landscape of phage therapy 利用机器学习和大数据技术绘制噬菌体治疗的全球专利版图
IF 33.1 1区 生物学
Nature biotechnology Pub Date : 2024-12-11 DOI: 10.1038/s41587-024-02493-9
Maxime Descartes Mbogning Fonkou, Jude Dzevela Kong
{"title":"Leveraging machine learning and big data techniques to map the global patent landscape of phage therapy","authors":"Maxime Descartes Mbogning Fonkou, Jude Dzevela Kong","doi":"10.1038/s41587-024-02493-9","DOIUrl":"10.1038/s41587-024-02493-9","url":null,"abstract":"A patent analysis of the phage therapy field underscores a dynamic, evolving landscape marked by regional disparities and a shift in research focus towards broad-spectrum medical applications and treatments for bacterial infections.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 12","pages":"1781-1791"},"PeriodicalIF":33.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41587-024-02493-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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