Nature Reviews Materials最新文献_第6页

A global policy framework for the circular use of forest biomass as building materials 关于循环利用森林生物量作为建筑材料的全球政策框架

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-02-03 DOI: 10.1038/s41578-025-00780-8

Victor De Araujo, Maximilian Pramreiter, André Christoforo

引用次数: 0

Large language models for reticular chemistry 网状化学的大型语言模型

IF 83.5 1区材料科学

Nature Reviews Materials Pub Date : 2025-02-01 DOI: 10.1038/s41578-025-00772-8

Zhiling Zheng, Nakul Rampal, Theo Jaffrelot Inizan, Christian Borgs, Jennifer T. Chayes, Omar M. Yaghi

{"title":"Large language models for reticular chemistry","authors":"Zhiling Zheng, Nakul Rampal, Theo Jaffrelot Inizan, Christian Borgs, Jennifer T. Chayes, Omar M. Yaghi","doi":"10.1038/s41578-025-00772-8","DOIUrl":"https://doi.org/10.1038/s41578-025-00772-8","url":null,"abstract":"<p>Reticular chemistry is the science of connecting molecular building units into crystalline extended structures such as metal–organic frameworks and covalent organic frameworks. Large language models (LLMs), a type of generative artificial intelligence system, can augment laboratory research in reticular chemistry by helping scientists to extract knowledge from literature, design materials and collect and interpret experimental data — ultimately accelerating scientific discovery. In this Perspective, we explore the concepts and methods used to apply LLMs in research, including prompt engineering, knowledge and tool augmentation and fine-tuning. We discuss how ‘chemistry-aware’ models can be tailored to specific tasks and integrated into existing practices of reticular chemistry, transforming the traditional ‘make, characterize, use’ protocol driven by empirical knowledge into a discovery cycle based on finding synthesis–structure–property–performance relationships. Furthermore, we explore how modular LLM agents can be integrated into multi-agent laboratory systems, such as self-driving robotic laboratories, to streamline labour-intensive tasks and collaborate with chemists and how LLMs can lower the barriers to applying generative artificial intelligence and data-driven workflows to such challenging research questions as crystallization. This contribution equips both computational and experimental chemists with the insights necessary to harness LLMs for materials discovery in reticular chemistry and, more broadly, materials science.</p>","PeriodicalId":19081,"journal":{"name":"Nature Reviews Materials","volume":"84 1","pages":""},"PeriodicalIF":83.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient catalyst for alkaline water 碱性水的高效催化剂

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-30 DOI: 10.1038/s41578-025-00776-4

Charlotte Allard

引用次数: 0

Make metal–organic frameworks safe and sustainable by design for industrial translation 为工业翻译设计安全、可持续的金属有机框架

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-29 DOI: 10.1038/s41578-025-00774-6

Swaroop Chakraborty, Dhruv Menon, Iuliia Mikulska, Christian Pfrang, David Fairen-Jimenez, Superb K. Misra, Iseult Lynch

引用次数: 0

Design of oxide nanoparticles for biomedical applications 用于生物医学应用的氧化物纳米颗粒的设计

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-29 DOI: 10.1038/s41578-024-00767-x

Bowon Lee, Yunjung Lee, Nohyun Lee, Dokyoon Kim, Taeghwan Hyeon

{"title":"Design of oxide nanoparticles for biomedical applications","authors":"Bowon Lee, Yunjung Lee, Nohyun Lee, Dokyoon Kim, Taeghwan Hyeon","doi":"10.1038/s41578-024-00767-x","DOIUrl":"10.1038/s41578-024-00767-x","url":null,"abstract":"Oxide nanoparticles have garnered significant attention in biomedical research owing to the numerous available synthetic approaches and highly tunable physicochemical properties, which enable diverse functions within biological systems. These nanoparticles can be broadly categorized based on their characteristics useful for biomedical applications. Magnetic oxide nanoparticles, for instance, are prominently used as contrast agents in MRI and as mediators to generate heat, mechanical force or electricity for therapy. Catalytic oxide nanoparticles can generate or eliminate reactive oxygen species, which are central to numerous biological processes. Porous oxide nanoparticles are adept at loading dye or drug molecules, making them invaluable for bioimaging and therapeutic interventions. In this Review, we highlight strategies for the fabrication and advanced engineering of oxide nanoparticles tailored for biomedical applications. We primarily focus on iron oxide, ceria and silica nanoparticles, delving into their diagnostic and therapeutic potentials. We also discuss future prospects and the challenges that must be addressed to meet clinical needs. Oxide nanoparticles, particularly iron oxide, ceria and silica nanoparticles, hold significant promise for biomedical applications owing to their unique magnetic, catalytic and porous properties. This Review highlights design strategies for their diagnostic and therapeutic uses and future clinical challenges.","PeriodicalId":19081,"journal":{"name":"Nature Reviews Materials","volume":"10 4","pages":"252-267"},"PeriodicalIF":79.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41578-024-00767-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modular lattice structures 模格结构

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-29 DOI: 10.1038/s41578-025-00778-2

Ariane Vartanian

引用次数: 0

Large-scale single MoS2 crystals unlocked 大规模单晶MoS2解锁

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-28 DOI: 10.1038/s41578-025-00777-3

Giulia Pacchioni

引用次数: 0

Author Correction: Emergence of melt and glass states of halide perovskite semiconductors 作者更正：卤化物钙钛矿半导体出现熔融态和玻璃态

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-27 DOI: 10.1038/s41578-025-00775-5

Akash Singh, David B. Mitzi

引用次数: 0

Delivering living medicines with biomaterials 用生物材料提供活体药物

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-27 DOI: 10.1038/s41578-024-00766-y

Tetsuhiro Harimoto, Wei-Hung Jung, David J. Mooney

{"title":"Delivering living medicines with biomaterials","authors":"Tetsuhiro Harimoto, Wei-Hung Jung, David J. Mooney","doi":"10.1038/s41578-024-00766-y","DOIUrl":"10.1038/s41578-024-00766-y","url":null,"abstract":"The engineering of therapeutic living cells through genetic programming is poised to transform medicine. Diverse living medicines, including mammalian cells, fungi, bacteria and viruses, are under development. However, for these medicines to progress in the clinic, new strategies are needed to successfully deliver them into the body. Unlike conventional small-molecule and protein-based biologics, living medicines present distinct challenges for delivery, including the need to maintain viability, control replication, manage metabolism and mitigate immunogenicity. This Review focuses on delivery strategies for living medicines, identifying key challenges and efforts to overcome them. We survey clinically adopted biomaterial strategies for delivering conventional drugs and explore how these approaches can be tailored for living medicines. Finally, we discuss remaining challenges and future directions towards next-generation living medicine delivery. As the field of engineered therapeutic living cells advances, new strategies to deliver them into the body are needed. This Review identifies current challenges in living medicine delivery and discusses how biomaterial strategies could be leveraged to overcome these clinical barriers.","PeriodicalId":19081,"journal":{"name":"Nature Reviews Materials","volume":"10 3","pages":"191-210"},"PeriodicalIF":79.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143050135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COP29 limps towards agreement on climate finance COP29在达成气候融资协议方面步履蹒跚

IF 79.8 1区材料科学

Nature Reviews Materials Pub Date : 2025-01-10 DOI: 10.1038/s41578-025-00771-9

Ariane Vartanian

引用次数: 0