Movement Disorders Clinical Practice最新文献_第3页

The Role of a Social Worker in the Deep Brain Stimulation Preoperative Evaluation: The DBS-FACTS Screening Tool. 社工在脑深部刺激术前评估中的作用：DBS-FACTS 筛选工具。

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-10 DOI: 10.1002/mdc3.70026

Amanda D Currie, Rachael M Burke, Alfonso Enrique Martinez Nunez, Alana McKay, Christopher W Hess, Justin D Hilliard, Michael S Okun

{"title":"The Role of a Social Worker in the Deep Brain Stimulation Preoperative Evaluation: The DBS-FACTS Screening Tool.","authors":"Amanda D Currie, Rachael M Burke, Alfonso Enrique Martinez Nunez, Alana McKay, Christopher W Hess, Justin D Hilliard, Michael S Okun","doi":"10.1002/mdc3.70026","DOIUrl":"https://doi.org/10.1002/mdc3.70026","url":null,"abstract":"Background: Social workers (SW) are part of multidisciplinary teams for many surgical disciplines. Their role in deep brain stimulation (DBS) presurgical evaluations has not been defined.Objectives: The goal was to characterize the role of SWs in a multidisciplinary DBS presurgical evaluation team and to construct a screening tool to identify patients who could benefit from a preoperative SW consultation.Methods: A retrospective chart review was conducted on 100 consecutive patients.Results: Ninety-seven subjects met with the SW. The median age was 68 years; 52% were female. Eight roles for the DBS SW were identified. The SW recommended follow-up for two subjects, and four additional subjects contacted the SW subsequently.Conclusions: This study revealed how SWs could be integrated into DBS presurgical evaluations. Because most patients do not have specific SW needs, the mnemonic DBS-FACTS (finances, advance care planning, caregivers, transportation, and suicide risk) may identify patients who could benefit from SW consultation.","PeriodicalId":19029,"journal":{"name":"Movement Disorders Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Face Reader: Jean-Martin Charcot (1825-1893) and Facial Expressions in Progressive Supranuclear Palsy. 面部阅读：让-马丁-沙尔科（1825-1893 年）与进行性核上性麻痹的面部表情。

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-10 DOI: 10.1002/mdc3.70035

Francesco Brigo

引用次数: 0

FIC Domain Protein Adenylyltransferase (FICD)-Related Complex Hereditary Spastic Paraplegia with Diabetes Mellitus.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-10 DOI: 10.1002/mdc3.70033

Adriana P Rebelo, Adel Alawwadh, Ali Hakami, Vanja Viric, Saeed Alshahrani, Marija Brankovic, Zorica Stevic, Stephan Zuchner, Abdulaziz Al-Shehri, Stojan Peric

引用次数: 0

Unmasking the Unexpected: FIG4-Related Disorder Presenting with Progressive Supranuclear Palsy-Like Features.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-10 DOI: 10.1002/mdc3.70037

Émilie Retailleau, George-Junior Kahwagi, Alexandre Obadia, Manon Philibert, Nathalie Patte-Karsenti, Jean-Philippe Brandel, Clément Desjardins

引用次数: 0

Delayed Normal Pressure Hydrocephalus after Deep Brain Stimulation in Parkinson's Disease.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-05 DOI: 10.1002/mdc3.70022

Sruthi Kola, Madhavi Karri, Sumaiya Sehrish, Syed Tazeem Fathima, Sindhuja Mohareer, Vanakuru Venkata Siva Rama Krishna Prasad, Rukmini Mridula Kandadai, Rajesh Alugolu, Ravi Varma, Rupam Borgohain

{"title":"Delayed Normal Pressure Hydrocephalus after Deep Brain Stimulation in Parkinson's Disease.","authors":"Sruthi Kola, Madhavi Karri, Sumaiya Sehrish, Syed Tazeem Fathima, Sindhuja Mohareer, Vanakuru Venkata Siva Rama Krishna Prasad, Rukmini Mridula Kandadai, Rajesh Alugolu, Ravi Varma, Rupam Borgohain","doi":"10.1002/mdc3.70022","DOIUrl":"https://doi.org/10.1002/mdc3.70022","url":null,"abstract":"Background: Deep brain stimulation (DBS) of the bilateral subthalamic nuclei (STN) or globus pallidus internus (GPi) for Parkinson's disease (PD) and dystonia is known for its efficacy despite potential complications. Although acute complications such as intracranial hemorrhage and infections are documented, delayed occurrences like normal pressure hydrocephalus (NPH) post-DBS has not been reported so far.Cases: We present a case series of seven PD patients (from 974) who developed NPH, an average of 10.9 + 3.1 years after DBS (6 STN, 1 GPi) with symptoms of cognitive decline and gait disturbances. Imaging confirmed hydrocephalus meeting NPH criteria (Radscale >4), which was further confirmed by the cerebrospinal fluid tap trial. Treatment with ventriculoperitoneal shunt placement showed significant symptom improvement.Conclusion: Recognizing NPH in PD patients even after DBS is crucial for early intervention and improved outcomes.","PeriodicalId":19029,"journal":{"name":"Movement Disorders Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Quality of Life Trend after Subthalamic Stimulation for Parkinson's Disease: An Updated Systematic Review and Meta-Analysis.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-05 DOI: 10.1002/mdc3.70025

Luis Otávio Nogueira, Angela Maria Sandini Corso, Louise Dalla Corte Dallé, Vanio L J Antunes, Matheus de M Fernandes, Isabella S M Rabelo, Marcus V Della Coletta, Carolina Candeias da Silva, Lorena Broseghini Barcelos, Henrique Ballalai Ferraz, Robson Luis Oliveira de Amorim, Dayany Leonel Boone

{"title":"Long-Term Quality of Life Trend after Subthalamic Stimulation for Parkinson's Disease: An Updated Systematic Review and Meta-Analysis.","authors":"Luis Otávio Nogueira, Angela Maria Sandini Corso, Louise Dalla Corte Dallé, Vanio L J Antunes, Matheus de M Fernandes, Isabella S M Rabelo, Marcus V Della Coletta, Carolina Candeias da Silva, Lorena Broseghini Barcelos, Henrique Ballalai Ferraz, Robson Luis Oliveira de Amorim, Dayany Leonel Boone","doi":"10.1002/mdc3.70025","DOIUrl":"https://doi.org/10.1002/mdc3.70025","url":null,"abstract":"Background: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a well-established treatment for Parkinson's Disease (PD). However, the long-term trajectory of Quality of Life (QoL) following STN-DBS remains underexplored.Objectives: We aimed to conduct a systematic review and meta-analysis to assess QoL trends up to five years after STN-DBS.Methods: We systematically searched PubMed, Embase, and Cochrane databases from inception to August 2024 for studies involving PD patients treated with bilateral STN-DBS, evaluating QoL using the Parkinson's Disease Questionnaire (PDQ), with a minimum follow-up of 12 months post-surgery. Continuous outcomes were pooled using standardized mean differences (SMD), and statistical analyses were conducted using R version 4.3.2.Results: Out of 4106 screened articles, 42 studies with a total of 2767 patients were included in the meta-analysis. QoL improvements were observed up to 36 months post-surgery (SMD 0.83; 95% CI 0.29 to 1.37), followed by a decline to pre-operative levels at 60 months (SMD -0.06; 95% CI -0.26 to 0.15). Subdomain analysis at 60 months revealed significant deterioration in cognitive function and communication. Meta-regression indicated that QoL improvements were independent of clinical and sociodemographic factors such as age, sex, and disease duration; however, there was a correlation with mean baseline PDQ (P = 0.01).Conclusions: This meta-analysis provides long-term QoL trends following STN-DBS, highlighting a further need to explore the factors driving the decline in QoL and develop strategies to mitigate this deterioration.","PeriodicalId":19029,"journal":{"name":"Movement Disorders Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motor Neuron Involvement in Two ATP13A2-Related Families: ALS And HSP-Like Phenotypes.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-03 DOI: 10.1002/mdc3.70027

Sepehr Khosravi, Elaheh Amini, Maziar Emamikhah, Afagh Alavi, Anthony E Lang, Mohammad Rohani

{"title":"Motor Neuron Involvement in Two ATP13A2-Related Families: ALS And HSP-Like Phenotypes.","authors":"Sepehr Khosravi, Elaheh Amini, Maziar Emamikhah, Afagh Alavi, Anthony E Lang, Mohammad Rohani","doi":"10.1002/mdc3.70027","DOIUrl":"https://doi.org/10.1002/mdc3.70027","url":null,"abstract":"Background: Mutations in the ATP13A2 gene have been implicated in various neurodegenerative disorders, including Kufor-Rakeb syndrome (KRS), neuronal ceroid lipofuscinosis (NCL), hereditary spastic paraplegia (HSP), and amyotrophic lateral sclerosis (ALS). This report presents two Iranian families with ATP13A2 variants exhibiting atypical features of KRS.Cases: We highlight four patients from two consanguineous Iranian families with mutations in the ATP13A2 gene presenting with variable features of motor neuron disease as well as juvenile-onset parkinsonism, and cognitive decline. The onset of symptoms ranged from 11 to 29 years, with initial manifestations including gait disturbance, postural instability, and cognitive impairment. As the disease progressed, patients developed a range of neurological signs, such as dystonia, spasticity, and dysarthria.Conclusion: This report expands the phenotypic spectrum of ATP13A2-related disorders, highlighting the potential overlap of symptoms associated with KRS, ALS, and HSP.","PeriodicalId":19029,"journal":{"name":"Movement Disorders Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive Effects of Caffeine Therapy in a Girl with PDE2A-Related Paroxysmal Dyskinesia.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-03 DOI: 10.1002/mdc3.70019

Katerina Bernardi, Moritz Thiel, Anne Koy

引用次数: 0

Reported Symptoms in Prodromal and Early Motor Parkinson's Disease: A Scoping Review on the Patient Perspective.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-03-03 DOI: 10.1002/mdc3.70007

Joseph Saade, Alice van Wyk, Glenn T Stebbins, Tiago A Mestre

{"title":"Reported Symptoms in Prodromal and Early Motor Parkinson's Disease: A Scoping Review on the Patient Perspective.","authors":"Joseph Saade, Alice van Wyk, Glenn T Stebbins, Tiago A Mestre","doi":"10.1002/mdc3.70007","DOIUrl":"https://doi.org/10.1002/mdc3.70007","url":null,"abstract":"Background: The lived experience of Parkinson's disease (PD) includes motor and non-motor symptoms. There is a need to capture the earliest patient experiences in a sensitive and reliable manner for the successful development of interventions that may delay clinical progression in PD.Objective: Our aim was to synthesize published literature about patient-reported symptoms in prodromal and early motor stages of PD and develop a conceptual framework of the earliest lived experiences in PD.Methods: We conducted a scoping review of the published literature in MEDLINE, EMBASE, SCOPUS, and CINAHL databases and abstracted patient-reported symptoms from included studies reporting on prodromal or early motor stages of PD populations.Results: We included 59 articles with data from 64 cohorts (prodromal PD: n = 20/64; 31%, early motor PD: n = 44/64, 69%). Overall, the 10 most frequent symptoms (of 85 standardized reported symptoms [SRSs]) were non-motor. SRSs were grouped into symptom domains (behavioral, cognition, dysautonomia, motor, sensory, sleep, and others) and functional domains (activities of daily living, communication, sexual, and social impairment). The Movement Disorder Society sponsored revision of the Unified Parkinson's Disease Rating Scale parts Ib and II (n = 13/64, 20%) and ad hoc questionnaires (n = 12/64, 19%) were the most frequently used measurement tools.Conclusion: At prodromal and early motor stages of PD, individuals report symptoms of a diverse range of motor and non-motor domains and higher-level functional domains. There is a need to capture the full spectrum of this lived experience in a new patient-reported clinical outcome measure for clinical trials in the earliest clinical stages of PD.","PeriodicalId":19029,"journal":{"name":"Movement Disorders Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 69-Year-Old Male with Subacute Gait Disturbance-Blastocystis hominis Causing Extensive Colitis with Thiamine Deficiency.

IF 2.6 4区医学

Movement Disorders Clinical Practice Pub Date : 2025-02-28 DOI: 10.1002/mdc3.70023

Yi-Cheng Tai, Malan Edward, Chin-Hsien Lin

引用次数: 0