Nature Plants最新文献

{"title":"Retrieval from vacuolar and endosomal compartments underpinning the neofunctionalization of SNARE in plants.","authors":"Yihong Feng,Kazuo Ebine,Yoko Ito,Takehiko Kanazawa,Tatsuya Sawasaki,Akira Nozawa,Tomohiro Uemura,Akihiko Nakano,Takashi Ueda","doi":"10.1038/s41477-025-02115-5","DOIUrl":"https://doi.org/10.1038/s41477-025-02115-5","url":null,"abstract":"A distinctive protein and lipid composition underlies the distinct function of each organelle, regulated by balanced anterograde and retrograde membrane trafficking. The vacuole, the largest plant organelle, is pivotal in various plant functions, and its protein composition is tightly regulated by bidirectional trafficking. However, the existence of retrograde transport from the plant vacuole has remained unverified. Here we demonstrate retrograde trafficking from the vacuole in Arabidopsis. We observed the retrieval of VAMP727, a plant-unique vacuolar membrane fusion machinery, from the vacuolar membrane. VAMP727 retrieval is facilitated by sorting nexin proteins, which independently diversified between plant and non-plant systems. Furthermore, we show that the core retromer complex and sorting nexins act independently in distinct retrograde transport events with specific cargos. Plant cells have thus elaborated a unique retrieval mechanism from the vacuole, underpinning the neofunctionalization of VAMP727 during plant evolution.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"94 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovery of iridoid cyclase completes the iridoid pathway in asterids.","authors":"Maite Colinas,Chloée Tymen,Joshua C Wood,Anja David,Jens Wurlitzer,Clara Morweiser,Klaus Gase,Ryan M Alam,Gabriel R Titchiner,John P Hamilton,Sarah Heinicke,Ron P Dirks,Adriana A Lopes,Lorenzo Caputi,C Robin Buell,Sarah E O'Connor","doi":"10.1038/s41477-025-02122-6","DOIUrl":"https://doi.org/10.1038/s41477-025-02122-6","url":null,"abstract":"Iridoids are specialized monoterpenes ancestral to asterid flowering plants1,2 that play key roles in defence and are also essential precursors for pharmacologically important alkaloids3,4. The biosynthesis of all iridoids involves the cyclization of the reactive biosynthetic intermediate 8-oxocitronellyl enol. Here, using a variety of approaches including single-nuclei sequencing, we report the discovery of iridoid cyclases from a phylogenetically broad sample of asterid species that synthesize iridoids. We show that these enzymes catalyse formation of 7S-cis-trans and 7R-cis-cis nepetalactol, the two major iridoid stereoisomers found in plants. Our work uncovers a key missing step in the otherwise well-characterized early iridoid biosynthesis pathway in asterids. This discovery unlocks the possibility to generate previously inaccessible iridoid stereoisomers, which will enable metabolic engineering for the sustainable production of valuable iridoid and iridoid-derived compounds.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"1 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The missing link in the iridoid puzzle.","authors":"Philipp Zerbe","doi":"10.1038/s41477-025-02133-3","DOIUrl":"https://doi.org/10.1038/s41477-025-02133-3","url":null,"abstract":"","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"12 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A nutrient-responsive chromatin complex balances growth and stress tolerance.","authors":"","doi":"10.1038/s41477-025-02118-2","DOIUrl":"https://doi.org/10.1038/s41477-025-02118-2","url":null,"abstract":"","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"120 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145209268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-kingdom mechanisms of trained immunity in plant systemic acquired resistance.","authors":"Uwe Conrath","doi":"10.1038/s41477-025-02119-1","DOIUrl":"https://doi.org/10.1038/s41477-025-02119-1","url":null,"abstract":"Plants face constant microbial threats and have evolved highly effective immune systems characterized by inducible defence mechanisms. On recognizing microbial patterns and/or effectors, plants activate localized pattern-triggered immunity and/or effector-triggered immunity, which culminate in systemic acquired resistance-a broad-spectrum immune response that enhances protection throughout the plant. Systemic acquired resistance shares striking similarities with mammalian trained immunity, particularly in defence priming, which equips organisms with an enhanced capacity to respond to subsequent infections. This Review explores the cross-kingdom similarities between systemic acquired resistance and trained immunity, emphasizing their potential to transform agricultural practices and medical therapies. These insights present innovative opportunities for developing new plant-protection strategies, producing disease-resistant crops and optimizing vaccine approaches, while also highlighting critical knowledge gaps to inspire future research.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"7 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrient-driven TOR signalling controls a chromatin-associated complex for orchestrating plant growth and stress tolerance.","authors":"Xin Wang,Zhen-Zhen Liu,Dan-Yang Yuan,Yu-Jia Lu,Lin Li,She Chen,Xin-Jian He","doi":"10.1038/s41477-025-02107-5","DOIUrl":"https://doi.org/10.1038/s41477-025-02107-5","url":null,"abstract":"The conserved target of rapamycin (TOR) kinase acts as a master regulator of growth by integrating nutrient and environmental signals in eukaryotes. However, how TOR influences chromatin remains poorly understood. Here we identified a multi-subunit complex in Arabidopsis thaliana, termed the chromatin-associated complex for growth (CACG). Our findings indicate that under nutrient-rich conditions, active TOR kinase enhances CACG mRNA translation, which is facilitated by pyrimidine-rich motifs in their 5' untranslated regions. CACG components co-occupy stress-responsive genes marked by histone acetylation, repressing their transcription to promote growth. Conversely, under nutrient-deficient conditions, inactive TOR reduces CACG mRNA translation, relieving transcriptional repression of stress-responsive genes and leading to increased stress tolerance but impaired growth. These results indicate that the CACG complex acts as a critical nutrient-responsive transcriptional regulator that is required for coordinating plant growth and stress tolerance in a TOR-dependent manner. The molecular mechanism revealed here could aid in developing high-yield crops capable of thriving in adverse environments.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"91 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing tree size across Amazonia.","authors":"Adriane Esquivel-Muelbert, Rebecca Banbury Morgan, Roel Brienen, Emanuel Gloor, Simon L Lewis, Kyle G Dexter, Everton Almeida, Edmar Almeida de Oliveira, Esteban Álvarez-Dávila, Atila Alves de Oliveira, Ana Andrade, Simone Aparecida Vieira, Luiz Aragão, Alejandro Araujo-Murakami, Eric Arets, Luzmila Arroyo, Gerardo Aymard-Corredor, Olaf Banki, Plinio Barbosa de Camargo, Jorcely Barroso, Lilian Blanc, Foster Brown, José Luís Camargo, Wendeson Castro, Victor Chama Moscoso, Jérôme Chave, Ezequiel Chavez, James Comiskey, Antônio Carlos Lola da Costa, Jhon Del Aguila Pasquel, Géraldine Derroire, Anthony Di Fiore, Sophie Fauset, Ted R Feldpausch, Gerardo Flores Llampazo, Rene Guillen Villaroel, Rafael Herrera, Niro Higuchi, Eurídice Honorio Coronado, Isau Huamantupa-Chuquimaco, Walter Huaraca Huasco, Eliana Jimenez, Timothy Killeen, Susan Laurance, William Laurance, Aurora Levesley, Gabriela Lopez-Gonzalez, Yadvinder Malhi, Beatriz Marimon, Ben Hur Marimon Junior, Simone Matias de Almeida Reis, Casimiro Mendoza Bautista, Irina Mendoza Polo, Abel Monteagudo-Mendoza, Paulo Sérgio Morandi, Adriano Nogueira Lima, Percy Núñez Vargas, Nadir Pallqui Camacho, Alexander Parada Gutierrez, Julie Peacock, Maria Cristina Peñuela-Mora, Georgia Pickavance, John Pipoly, Nigel Pitman, Adriana Prieto, Carlos Quesada, Freddy Ramirez Arevalo, Maxime Réjou-Méchain, Zorayda Restrepo Correa, Rocio Rojas, Lily Rodriguez Bayona, Anand Roopsind, Rafael Salomão, Natalino Silva, Javier Silva Espejo, Marcos Silveira, Juliana Stropp, Joey Talbot, Hans Ter Steege, John Terborgh, Raquel Thomas, Luis Valenzuela Gamarra, Peter van der Hout, Rodolfo Vasquez Martinez, Ima Célia Guimarães Vieira, Emilio Vilanova, Roderick Zagt, Timothy R Baker, Oliver L Phillips","doi":"10.1038/s41477-025-02097-4","DOIUrl":"10.1038/s41477-025-02097-4","url":null,"abstract":"<p><p>Climate change and increasing availability of resources such as carbon dioxide are modifying forest functioning worldwide, but the effects of these changes on forest structure are unclear. As additional resources become available, for example, through CO₂ fertilization or nitrogen deposition, large trees, with greater access to light, may be expected to gain further advantages. Conversely, smaller light-suppressed trees might benefit more if their light compensation point changes, while bigger trees may be the most negatively impacted by increasing heat and drought. We assessed recent changes in the structure of Earth's largest tropical forest by analysing 30 years of Amazonian tree records across 188 mature forest plots. We find that, at a stand level, trees have become larger over time, with mean tree basal area increasing by 3.3% per decade (95% CI 2.4; 4.1). Larger trees have increased in both number and size, yet we observed similar rates of relative size gain in large and small trees. This evidence is consistent with a resource-driven boost for larger trees but also a reduction in suppression among smaller trees. These results, especially the persistence and consistency of tree size increases across Amazonian forest plots, communities and regions, indicate that any negative impacts of climate change on forests and large trees here have so far been mitigated by the positive effects of increased resources.</p>","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":" ","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Correction: Laboratory evolution of Rubisco solubility and catalytic switches to enhance plant productivity.","authors":"Matteo Gionfriddo, Rosemary Birch, Timothy Rhodes, Sally Buck, Tanya Skinner, Inger Andersson, Spencer Whitney","doi":"10.1038/s41477-025-02136-0","DOIUrl":"https://doi.org/10.1038/s41477-025-02136-0","url":null,"abstract":"","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":" ","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping.","authors":"Helen J Brabham, Inmaculada Hernández-Pinzón, Chizu Yanagihara, Noriko Ishikawa, Toshiyuki Komori, Oadi N Matny, Amelia Hubbard, Kamil Witek, Alexis Feist, Hironobu Numazawa, Phon Green, Antonín Dreiseitl, Naoki Takemori, Toshihiko Komari, Roger P Freedman, Brian Steffenson, H Peter van Esse, Matthew J Moscou","doi":"10.1038/s41477-025-02110-w","DOIUrl":"https://doi.org/10.1038/s41477-025-02110-w","url":null,"abstract":"<p><p>Protecting crops from diseases is vital for the sustainable agricultural systems that are needed for food security. Introducing functional resistance genes to enhance the plant immune system is highly effective for disease resistance, but identifying new immune receptors is resource intensive. We observed that functional immune receptors of the nucleotide-binding domain leucine-rich repeat (NLR) class show a signature of high expression in uninfected plants across both monocot and dicot species. Here, by exploiting this signature combined with high-throughput transformation, we generated a wheat transgenic array of 995 NLRs from diverse grass species to identify new resistance genes for wheat. Confirming this proof of concept, we identified new resistance genes against the stem rust pathogen Puccinia graminis f. sp. tritici and the leaf rust pathogen Puccinia triticina, both major threats to wheat production. This pipeline facilitates the rapid identification of candidate NLRs and provides in planta gene validation of resistance. The accelerated discovery of new NLRs from a large gene pool of diverse and non-domesticated plant species will enhance the development of disease-resistant crops.</p>","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":" ","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closing the divide between academia and industry.","authors":"Catherine Walker","doi":"10.1038/s41477-025-02123-5","DOIUrl":"https://doi.org/10.1038/s41477-025-02123-5","url":null,"abstract":"","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"40 1","pages":""},"PeriodicalIF":18.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145127111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}