发布求助
文献互助 智能选刊 最新文献

Nature Reviews Microbiology最新文献

筛选
英文 中文
Biosynthesis and function of magnetic organelles in magnetotactic bacteria. 趋磁细菌中磁性细胞器的生物合成及功能。
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-19 DOI: 10.1038/s41579-025-01234-2
Dirk Schüler,Marina Dziuba,Daniel Pfeiffer,René Uebe
{"title":"Biosynthesis and function of magnetic organelles in magnetotactic bacteria.","authors":"Dirk Schüler,Marina Dziuba,Daniel Pfeiffer,René Uebe","doi":"10.1038/s41579-025-01234-2","DOIUrl":"https://doi.org/10.1038/s41579-025-01234-2","url":null,"abstract":"One of the most intricate structures found in bacterial cells are magnetosomes of magnetotactic bacteria. These membrane-bound organelles contain tens-of-nanometre-sized crystals of a magnetic iron mineral that are usually aligned in well-ordered chains and function as sensors for geomagnetic field navigation in their aquatic habitats. Magnetosomes emerged as a model to study bacterial cell biology, organelle biogenesis and biomineralization, but they are also of interest as 'magnetofossils' in geoscience and have potential for various biotechnological applications. Recent work has unveiled a vast structural and genetic complexity of magnetosome biosynthesis. In this Review, we summarize current knowledge of magnetosome formation and organization within the cell, with emphasis on two established magnetospirilla model species. We highlight the function, diversity and potential applications of magnetosomes and discuss open questions for future research.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"41 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145089895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Warming waters, declining Prochlorococcus 海水升温，原绿球藻衰亡。
IF 103.3 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-18 DOI: 10.1038/s41579-025-01244-0
Andrea Du Toit
{"title":"Warming waters, declining Prochlorococcus","authors":"Andrea Du Toit","doi":"10.1038/s41579-025-01244-0","DOIUrl":"10.1038/s41579-025-01244-0","url":null,"abstract":"This study reports the possible negative effects of warming sea surface temperatures on Prochlorococcus populations.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"23 11","pages":"682-682"},"PeriodicalIF":103.3,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Cryptosporidium parvum fitness factor 新的小隐孢子虫适合度因子。
IF 103.3 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-17 DOI: 10.1038/s41579-025-01241-3
Shimona Starling
{"title":"New Cryptosporidium parvum fitness factor","authors":"Shimona Starling","doi":"10.1038/s41579-025-01241-3","DOIUrl":"10.1038/s41579-025-01241-3","url":null,"abstract":"A new study by Huang et al. identifies a Cryptosporidium parvum ABC transporter that confers resistance to a toxic gut microbial metabolite.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"23 11","pages":"683-683"},"PeriodicalIF":103.3,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines 疟疾中的红细胞侵袭：从分子机制到合理的疫苗
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-15 DOI: 10.1038/s41579-025-01235-1
Nawsad Alam, Brendan Farrell, Abhishek Jamwal, Matthew K. Higgins
{"title":"Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines","authors":"Nawsad Alam, Brendan Farrell, Abhishek Jamwal, Matthew K. Higgins","doi":"10.1038/s41579-025-01235-1","DOIUrl":"https://doi.org/10.1038/s41579-025-01235-1","url":null,"abstract":"<p><i>Plasmodium</i> parasites, which cause malaria, invade and remodel our red blood cells, creating niches in which they replicate. If erythrocyte invasion is blocked during the blood stage of infection, malaria can be prevented. Indeed, a vaccine that targets a component of the erythrocyte invasion machinery has recently shown efficacy against malaria. Erythrocyte invasion occurs through a sequence of temporally organized molecular processes, such as bridging of the erythrocyte and parasite membranes during invasion by the <i>Plasmodium falciparum</i> PCRCR complex. Structural investigations of human antibodies that target invasion machinery, induced by vaccination or natural infection, have revealed neutralizing epitopes and uncovered mechanisms by which antibodies can potentiate the activity of other antibodies. Using rational, structure-guided protein design, these insights are being leveraged to develop targeted vaccine components, with the first rationally designed blood-stage malaria vaccine immunogen now entering clinical trials.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"28 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial stewardship from a One Health perspective 从同一个健康的角度看抗菌剂管理
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-10 DOI: 10.1038/s41579-025-01233-3
Rodney James, Laura Y. Hardefeldt, Courtney Ierano, Esmita Charani, Leslie Dowson, Sri Elkins, Karin Thursky
{"title":"Antimicrobial stewardship from a One Health perspective","authors":"Rodney James, Laura Y. Hardefeldt, Courtney Ierano, Esmita Charani, Leslie Dowson, Sri Elkins, Karin Thursky","doi":"10.1038/s41579-025-01233-3","DOIUrl":"https://doi.org/10.1038/s41579-025-01233-3","url":null,"abstract":"<p>The global rise of antimicrobial resistance (AMR) poses a profound threat to human, animal and environmental health. Although antimicrobials have revolutionized modern medicine, their overuse and misuse have accelerated AMR, necessitating urgent, multisectoral action. Antimicrobial stewardship (AMS), a set of coordinated strategies that promote responsible antimicrobial use, has emerged as a key intervention in managing AMR. In this Review, we explore AMS within a One Health framework, emphasizing interconnectedness across sectors. We examine clinical, economic, sociocultural and environmental drivers of antimicrobial use, highlighting disparities between high-income and low-income settings and identifying context-specific challenges to implementation. We also discuss the importance of governance, financing, digital innovation, surveillance and behavioural science in shaping sustainable AMS programmes, and we consider core components, such as policy integration, surveillance of appropriateness, and context-aware interventions. This Review ultimately advocates for equity-focused strategies that better account for structural barriers, support marginalized populations, and ensure global access to high-quality antimicrobials. By aligning political will, funding and scientific innovation, AMS programmes can be scaled effectively to preserve antimicrobial efficacy, mitigate AMR, improve health outcomes, and promote global health security. The paper concludes with key recommendations for embedding AMS across sectors as a sustainable response to AMR.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"31 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145025500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-species transmission risks in farmed and wild mammals 养殖和野生哺乳动物的跨物种传播风险
IF 103.3 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-09-10 DOI: 10.1038/s41579-025-01240-4
Shimona Starling
{"title":"Cross-species transmission risks in farmed and wild mammals","authors":"Shimona Starling","doi":"10.1038/s41579-025-01240-4","DOIUrl":"10.1038/s41579-025-01240-4","url":null,"abstract":"A study by Shi et al. uncovers uncharted diversity of potential pathogens and mobile antibiotic resistance genes in samples from wild mammals and non-traditional farmed mammals","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"23 11","pages":"682-682"},"PeriodicalIF":103.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145025499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Correction: The human skin microbiome: from metagenomes to therapeutics 作者更正：人类皮肤微生物组：从宏基因组到治疗学
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-08-29 DOI: 10.1038/s41579-025-01238-y
Julia Oh, Anita Y. Voigt
{"title":"Author Correction: The human skin microbiome: from metagenomes to therapeutics","authors":"Julia Oh, Anita Y. Voigt","doi":"10.1038/s41579-025-01238-y","DOIUrl":"https://doi.org/10.1038/s41579-025-01238-y","url":null,"abstract":"<p>Correction to: <i>Nature Reviews Microbiology</i> https://doi.org/10.1038/s41579-025-01211-9, published online 4 August 2025.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"36 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144915663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methicillin-resistant and susceptible Staphylococcus aureus: tolerance, immune evasion and treatment 耐甲氧西林和敏感金黄色葡萄球菌：耐受性、免疫逃避和治疗
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-08-20 DOI: 10.1038/s41579-025-01226-2
Joshua B. Parsons, Ahmad Mourad, Brian P. Conlon, Tammy Kielian, Vance G. Fowler
{"title":"Methicillin-resistant and susceptible Staphylococcus aureus: tolerance, immune evasion and treatment","authors":"Joshua B. Parsons, Ahmad Mourad, Brian P. Conlon, Tammy Kielian, Vance G. Fowler","doi":"10.1038/s41579-025-01226-2","DOIUrl":"https://doi.org/10.1038/s41579-025-01226-2","url":null,"abstract":"<p><i>Staphylococcus aureus</i> is capable of infecting every organ system in the body and developing resistance to every available antibiotic used to treat it, such as methicillin-resistant <i>S.</i> <i>aureus</i> (commonly referred to as MRSA). This pathogen is characterized by the sudden emergence of virulent new clones and an array of mechanisms to circumvent the immune system and antibiotics. Furthermore, despite the development of new antibiotics and a growing body of high-quality data to inform their use, <i>S.</i> <i>aureus</i> continues to be a leading bacterial cause of death worldwide. In this Review, we provide an overview of the basic research on the complex interplay between <i>S.</i> <i>aureus</i>, the host and antibiotics. We also provide an update on the contemporary clinical studies on the treatment and prevention of <i>S.</i> <i>aureus</i>.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"25 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respiratory viral coinfections: interactions, mechanisms and clinical implications 呼吸道病毒共感染：相互作用、机制和临床意义
IF 88.1 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-08-20 DOI: 10.1038/s41579-025-01225-3
Pallavi Deol, Tanya A. Miura
{"title":"Respiratory viral coinfections: interactions, mechanisms and clinical implications","authors":"Pallavi Deol, Tanya A. Miura","doi":"10.1038/s41579-025-01225-3","DOIUrl":"https://doi.org/10.1038/s41579-025-01225-3","url":null,"abstract":"<p>Many heterologous viruses that infect the respiratory tract co-circulate within human populations. With the advent of multiplex diagnostic tests for respiratory viruses, there is increased appreciation of viral coinfection within an individual host. Thus, it is important to understand the interactions between heterologous respiratory viruses at the levels of populations, hosts and cells, as well as the impact of these interactions on pathogen prevalence and disease severity. In this Review, we summarize studies that demonstrate antagonistic or synergistic interactions between respiratory viruses, resulting in altered viral prevalence in populations, replication in hosts and cells, and disease severity in clinical cases and animal models. Understanding these interactions at a mechanistic level will affect future strategies to prevent and treat respiratory viral infections.</p>","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"16 1","pages":""},"PeriodicalIF":88.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The wood microbiome inside living trees 活树体内的木材微生物群。
IF 103.3 1区 生物学
Nature Reviews Microbiology Pub Date : 2025-08-18 DOI: 10.1038/s41579-025-01236-0
Shimona Starling
{"title":"The wood microbiome inside living trees","authors":"Shimona Starling","doi":"10.1038/s41579-025-01236-0","DOIUrl":"10.1038/s41579-025-01236-0","url":null,"abstract":"This study presents the microbiome inhabiting the wood of living trees.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":"23 10","pages":"618-618"},"PeriodicalIF":103.3,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信