Nature Reviews Microbiology最新文献

Urea reshuffles soil microbial balance. 尿素重新洗刷土壤微生物平衡。

IF 104.6 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-20 DOI: 10.1038/s41579-026-01392-x

Agustina Taglialegna

引用次数: 0

Mosquito-based malaria control through genetic, microbial and immunological innovations. 通过基因、微生物和免疫学创新控制蚊媒疟疾。

IF 104.6 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-13 DOI: 10.1038/s41579-026-01382-z

Yuemei Dong, Shengzhang Dong, George Dimopoulos

{"title":"Mosquito-based malaria control through genetic, microbial and immunological innovations.","authors":"Yuemei Dong, Shengzhang Dong, George Dimopoulos","doi":"10.1038/s41579-026-01382-z","DOIUrl":"https://doi.org/10.1038/s41579-026-01382-z","url":null,"abstract":"Malaria remains a major global health challenge, causing approximately 600,000 deaths annually despite decades of progress using insecticide-based and drug-based interventions. These core tools are increasingly compromised by widespread insecticide resistance in mosquitoes, drug resistance in parasites, adaptive vector behaviours and the lack of highly effective vaccines, together with logistical and sustainability constraints. Complementary strategies, including larval source management, environmental modification and novel insecticide formulations, also require sustained investment and strong community engagement. Novel Plasmodium transmission-blocking and Anopheles population-suppressing technologies, based on transgenic gene drives, natural and engineered microorganisms, and transmission-blocking vaccines and drugs, have the potential to redefine malaria control by providing parallel, sustainable, mosquito-targeted interventions. In this Review, we synthesize scientific advances underpinning these innovations, identify key knowledge gaps and discuss the science-based safeguards necessary for the responsible implementation of these malaria control strategies.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":" ","pages":""},"PeriodicalIF":104.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growing forests to support soil health. 种植森林以支持土壤健康。

IF 104.6 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-13 DOI: 10.1038/s41579-026-01385-w

Andrea Du Toit

引用次数: 0

The role of the respiratory microbiome in acute and chronic respiratory diseases. 呼吸道微生物组在急性和慢性呼吸道疾病中的作用。

IF 104.6 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-09 DOI: 10.1038/s41579-026-01377-w

Lauren R Heinzinger, Leopoldo N Segal, Robert P Dickson

{"title":"The role of the respiratory microbiome in acute and chronic respiratory diseases.","authors":"Lauren R Heinzinger, Leopoldo N Segal, Robert P Dickson","doi":"10.1038/s41579-026-01377-w","DOIUrl":"https://doi.org/10.1038/s41579-026-01377-w","url":null,"abstract":"The lungs, once considered sterile, are now known to contain diverse, dynamic microbial communities that are metabolically active and immunologically consequential even in health. In respiratory disease, these communities undergo quantitative and compositional changes that predict clinical trajectories and may contribute to pathogenesis. The past decade of research has advanced our understanding of the complex bidirectional relationship between the respiratory tract and the microbial communities it encounters. In health, the lungs are nutrient poor and defended by robust host defences, limiting local microbial growth and keeping bacterial populations sparse and transient. Yet, in respiratory disease, the ecological conditions of the lungs permit and promote the outgrowth of select microorganisms. Recent in vivo and ex vivo discoveries explain how this respiratory dysbiosis is both a cause and a consequence of airway and alveolar injury. To leverage the respiratory microbiome for therapeutic benefit, we must interrogate both how disease-altered microbial communities shape immune responses, treatment efficacy and outcomes, and how host and environmental factors, in turn, shape the respiratory microbiome. In this Review, we synthesize current insights into how the respiratory microbiome contributes to chronic and acute lung diseases and explore its clinical implications for diagnosis, prognosis and therapy.","PeriodicalId":18838,"journal":{"name":"Nature Reviews Microbiology","volume":" ","pages":""},"PeriodicalIF":104.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remediation restores soil carbon 修复恢复土壤碳

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-07 DOI: 10.1038/s41579-026-01384-x

Andrea Du Toit

引用次数: 0

Towards broader-spectrum direct-acting antivirals against RNA viruses 开发针对RNA病毒的广谱直接抗病毒药物

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-07 DOI: 10.1038/s41579-026-01372-1

Hendrik Jan Thibaut,Dirk Jochmans,Christophe Van Dijck,Manon Laporte,Laurens Liesenborghs,Johan Neyts

引用次数: 0

Predicting resistance evolution to guide antibiotic development 预测耐药性演变以指导抗生素开发

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-07 DOI: 10.1038/s41579-026-01373-0

Csaba Pál,Petra Szili,Szilvia Juhász

引用次数: 0

Cities cannot go green without soil microorganisms 没有土壤微生物，城市不可能变绿

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-02 DOI: 10.1038/s41579-026-01380-1

Stefanie Schulz,Michael Schloter

引用次数: 0

How bacterial immune systems sense phage infection 细菌免疫系统如何感知噬菌体感染

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-02 DOI: 10.1038/s41579-026-01376-x

Daniel S. Saxton,Michael T. Laub

引用次数: 0

Microbial ecology of shallow groundwater ecosystems 浅层地下水生态系统微生物生态学

IF 88.1 1区生物学

Nature Reviews Microbiology Pub Date : 2026-10-01 DOI: 10.1038/s41579-026-01362-3

Clemens Karwautz,Christian Griebler

引用次数: 0