NaturePub Date : 2026-10-15DOI: 10.1038/d41586-026-03152-6
Rachel Fieldhouse
{"title":"Give me the good news: four science stories to brighten your day.","authors":"Rachel Fieldhouse","doi":"10.1038/d41586-026-03152-6","DOIUrl":"10.1038/d41586-026-03152-6","url":null,"abstract":"","PeriodicalId":18787,"journal":{"name":"Nature","volume":" ","pages":""},"PeriodicalIF":56.1,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149195073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/d41586-026-03219-4
{"title":"Protecting nature means valuing biodiversity","authors":"","doi":"10.1038/d41586-026-03219-4","DOIUrl":"10.1038/d41586-026-03219-4","url":null,"abstract":"Appeals for extra money are failing. Fundamental changes are needed to safeguard the planet for future generations.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"658 8136","pages":"579-580"},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41586-026-03219-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/s41586-026-11117-y
Katerina Vaxevani, Jon Ortuzar, Stefano Trivini, Georg Monninger, Dongfei Wang, Manuel Vilas-Varela, Lucía Gómez-Rodrigo, Diego Peña, Jose Ignacio Pascual
{"title":"Parity-dependent coupling of molecular spin chains to a superconductor","authors":"Katerina Vaxevani, Jon Ortuzar, Stefano Trivini, Georg Monninger, Dongfei Wang, Manuel Vilas-Varela, Lucía Gómez-Rodrigo, Diego Peña, Jose Ignacio Pascual","doi":"10.1038/s41586-026-11117-y","DOIUrl":"10.1038/s41586-026-11117-y","url":null,"abstract":"Collective behaviour in quantum materials can produce excitations carrying only a fraction of the quantum numbers of their constituents. A notable case occurs in chains of spin-1 units1, in which a topological gap protects the interior of the chain, whereas spin-1/2 states, half the spin of the units that form it, emerge at the ends2. In short chains, these fractional edge spins couple to each other and their topological protection makes them attractive for hybrid spin–superconductor devices. Whether such fractionalization survives the proximity of a superconducting condensate, however, remains an open question. Here we grow molecular Haldane chains of antiferromagnetically coupled spin-1 triangulene units on a proximitized Au(111)/Nb(110) surface and resolve a parity-dependent coupling of their spin-1/2 edge states to the superconductor by scanning tunnelling spectroscopy. Odd-length chains host Yu–Shiba–Rusinov (YSR) bound states inside the superconducting gap, originating from a global S = 1 ground state, whereas even-length chains form an S = 0 ground state decoupled from the superconductor. A two-site model attributes this alternation to the sign and strength of inter-edge interactions, independently confirmed by extra-gap spin excitations in tunnelling spectra. Many-body spin excitations of the S = 1 chain are also detected, decoupled from the superconductor by the much larger Haldane gap. The length-tunable coupling of the edge spins to superconductors opens a route towards molecular spin qubits based on π-conjugated carbon architectures. Scanning tunnelling spectroscopy shows that the fractional spin-1/2 end states of molecular Haldane chains couple differently to a superconducting condensate depending on whether the chain contains an even or odd number of spin-1 triangulene units.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"658 8136","pages":"617-622"},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/s41586-026-11138-7
James M. Stevenson, Garvit Agarwal, Sibali Debnath, Zachary K. Goldsmith, Monosij Mondal, Asya Svirinovsky-Arbeli, In Won Yeu, Amy S. Metlay, Yongbeom Kwon, Lakshmi Bhai, Rishabh D. Guha, Eric G. Keeler, John L. Weber, Daniel A. Steingart, Lauren E. Marbella, Alexander Urban, Leif D. Jacobson, Mathew D. Halls, Richard A. Friesner
{"title":"Evidence for multi-Li+ clustering in lithium-ion battery electrolytes","authors":"James M. Stevenson, Garvit Agarwal, Sibali Debnath, Zachary K. Goldsmith, Monosij Mondal, Asya Svirinovsky-Arbeli, In Won Yeu, Amy S. Metlay, Yongbeom Kwon, Lakshmi Bhai, Rishabh D. Guha, Eric G. Keeler, John L. Weber, Daniel A. Steingart, Lauren E. Marbella, Alexander Urban, Leif D. Jacobson, Mathew D. Halls, Richard A. Friesner","doi":"10.1038/s41586-026-11138-7","DOIUrl":"10.1038/s41586-026-11138-7","url":null,"abstract":"In lithium-ion batteries, the bulk solvation structure of the electrolyte is a major determinant of the physical and electrochemical properties of the cell, for example, conductivity, viscosity, salt dissociation and subsequent reactivity, the electrochemical stability window (and thus solid electrolyte interphase formation), and the composition of the electrochemical double layer1–3. However, elucidation of this structure at an atomic level of detail has been challenging to accomplish via a purely experimental approach. Here we combine machine-learning-enabled atomistic simulations4–16, nuclear magnetic resonance spectroscopy, electrochemical data3,17–20 and quantum-chemical calculations to reveal previously unstudied multi-Li+ complexes without bound anions that are uniquely facile for reduction. This insight explains the success of empirically chosen ethylene-carbonate-containing solvent mixtures and provides a foundation for the rational design of improved electrolytes. Furthermore, our machine-learning force-field-based lithium-ion-battery electrolyte simulations accurately reproduce a wide range of condensed-phase experiments3,21–24, despite being parameterized to only quantum-chemical gas-phase cluster calculations, and hence provide a compelling demonstration that machine-learning force-field-based models developed from first principles can robustly represent a complex chemical system to atomic resolution. Machine-learning-enabled atomistic simulations, spectroscopy, electrochemical data and quantum-chemical calculations reveal previously unstudied multi-lithium-ion complexes without bound anions, improving understanding of lithium-ion-battery functionality at the atomic level.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"658 8136","pages":"636-642"},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41586-026-11138-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/d41586-026-03302-w
Mariana Lenharo
{"title":"Overlooked brown fat in our bodies linked to wide range of health benefits.","authors":"Mariana Lenharo","doi":"10.1038/d41586-026-03302-w","DOIUrl":"10.1038/d41586-026-03302-w","url":null,"abstract":"","PeriodicalId":18787,"journal":{"name":"Nature","volume":" ","pages":""},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/d41586-026-03075-2
{"title":"Large blind test of methane-detecting satellites lends credibility to emissions data.","authors":"","doi":"10.1038/d41586-026-03075-2","DOIUrl":"https://doi.org/10.1038/d41586-026-03075-2","url":null,"abstract":"","PeriodicalId":18787,"journal":{"name":"Nature","volume":" ","pages":""},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/s41586-026-10972-z
Liming Xu (, ), Min Wang (, ), Ganmin Lin (, ), Liping Dong (, ), Ke Deng (, ), Xing Xu (, ), Honggang Du (, ), Min Lin (, ), Runsheng Chen (, ), Zhonghe Zhou (, )
{"title":"Jurassic flightless bird reveals early ecological diversity of avialans","authors":"Liming Xu \u0000 (, ), Min Wang \u0000 (, ), Ganmin Lin \u0000 (, ), Liping Dong \u0000 (, ), Ke Deng \u0000 (, ), Xing Xu \u0000 (, ), Honggang Du \u0000 (, ), Min Lin \u0000 (, ), Runsheng Chen \u0000 (, ), Zhonghe Zhou \u0000 (, )","doi":"10.1038/s41586-026-10972-z","DOIUrl":"10.1038/s41586-026-10972-z","url":null,"abstract":"The origin and early diversification of birds remain highly debated in vertebrate evolution. Although estimates of the evolutionary timescales suggest a Jurassic period radiation1,2, a profound scarcity of fossils from this period has hampered how the distinctive bird bauplan was assembled3–5. Selection for powered flight has been viewed as the primary driver of early avialan skeletal modifications3,6,7, attesting to the independent occurrences of aerodynamic features among paravian lineages8. Here we report on the discovery of a Late Jurassic avialan, Yuezhuornis yangyuanensis, gen. et sp. nov., from the Zhenghe Fauna of southeastern China9. As one of the earliest diverging avialans, Y. yangyuanensis exhibits a striking mosaic of features, combining a mixture of avialan- and troodontid-like cranial characters, paired with derived postcranial traits and a deinonychosaur-like hyperextensible second pedal digit. Phylogenetically informed analyses show that Y. yangyuanensis possesses markedly short forelimbs—a condition present widely among non-avialan theropods. These findings provide strong evidence for a terrestrial, flightless lifestyle of Y. yangyuanensis. Our study demonstrates that evolution works intensively as exemplified by the occurrence of several, divergent ecological pathways being exploited in the initial diversification of birds. A fossil bird from the Upper Jurassic Zhenghe Fauna of southeastern China contemporary with Archaeopteryx and that clearly could not fly sheds new light on the ecological diversification of early-diverging avialans.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"658 8136","pages":"690-697"},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/d41586-026-02645-8
Fernando E. Novas
{"title":"Some Jurassic period birds were flightless","authors":"Fernando E. Novas","doi":"10.1038/d41586-026-02645-8","DOIUrl":"10.1038/d41586-026-02645-8","url":null,"abstract":"The fossil discovery of an early avian ancestor in China reveals that flightless birds lived alongside the known flying species.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"658 8136","pages":"609-610"},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149177723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NaturePub Date : 2026-10-14DOI: 10.1038/s41586-026-11162-7
Nicolás Gómez-Banoy, Jorge A Barrero, Luiza Rachel Pinheiro de Carvalho, Caroline S Jiang, Tara Doma Lama, Nakul Karandikar, Mascha Koenen, Tiffany Lam, Kaja Plucińska, Ksenia Morozova, Stephanie Chahwan, Gustavo Barraza, Burcin Agridag Ucpinar, Jennifer E Liu, Rohit Sharma, Daniel Lafontaine, Heiko Schöder, Paul Cohen
{"title":"Artificial intelligence-enabled clinical phenotyping of human brown fat.","authors":"Nicolás Gómez-Banoy, Jorge A Barrero, Luiza Rachel Pinheiro de Carvalho, Caroline S Jiang, Tara Doma Lama, Nakul Karandikar, Mascha Koenen, Tiffany Lam, Kaja Plucińska, Ksenia Morozova, Stephanie Chahwan, Gustavo Barraza, Burcin Agridag Ucpinar, Jennifer E Liu, Rohit Sharma, Daniel Lafontaine, Heiko Schöder, Paul Cohen","doi":"10.1038/s41586-026-11162-7","DOIUrl":"https://doi.org/10.1038/s41586-026-11162-7","url":null,"abstract":"<p><p>Adipose tissue has a central role in systemic energy balance and the pathogenesis of obesity and its sequelae<sup>1,2</sup>. In contrast to white adipose tissue, brown adipose tissue (BAT) uses energy to produce heat<sup>3</sup>. Detectable BAT in humans is associated with decreased prevalence of cardiometabolic diseases<sup>4</sup>. However, the complete spectrum of health conditions associated with BAT remains unknown, and high-throughput methods to quantify BAT activity in humans are lacking<sup>5,6</sup>. Here we leveraged big data and artificial intelligence to systematically define the clinical impact of BAT in a cohort of 101,243 patients from a large cancer centre. Our unbiased analyses revealed that, across all diagnoses, cardiovascular and psychiatric diseases were less prevalent in people with BAT. Using a machine learning approach, we semi-automatically quantified BAT activity in approximately 8,700 patients and demonstrated that higher BAT activity, especially in the axillary depot, is associated with lower odds of cardiometabolic diseases and healthier white fat distribution. People with BAT also exhibited more favourable glycaemic parameters, lipid profiles, inflammatory markers and echocardiographic indices. Analysis of medication usage demonstrated that angiotensin receptor blocker use was positively associated with BAT presence. As proof of concept, we showed that the angiotensin receptor blocker losartan increased brown adipocyte activity and whole-body energy expenditure. Altogether, our studies harnessing artificial intelligence and big data identify new clinical phenotypes linked to BAT and serve as a platform for drug repurposing to activate this tissue in humans.</p>","PeriodicalId":18787,"journal":{"name":"Nature","volume":" ","pages":""},"PeriodicalIF":56.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}