Molecular plant pathology最新文献_第7页

SLCMV-Encoded BC1 Protein Suppresses Photosynthesis by Disrupting Chloroplast Structure and Gene Expression. slcmv编码的BC1蛋白通过破坏叶绿体结构和基因表达抑制光合作用。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-07-01 DOI: 10.1111/mpp.70302

Yu-Jiao Ma, Chao Zheng, Jian-Ping Chen, Xiao-Wei Wang, Ping Li

{"title":"SLCMV-Encoded BC1 Protein Suppresses Photosynthesis by Disrupting Chloroplast Structure and Gene Expression.","authors":"Yu-Jiao Ma, Chao Zheng, Jian-Ping Chen, Xiao-Wei Wang, Ping Li","doi":"10.1111/mpp.70302","DOIUrl":"10.1111/mpp.70302","url":null,"abstract":"Sri Lankan cassava mosaic virus (SLCMV) is a highly destructive plant virus that poses a significant threat to cassava cultivation. It causes severe symptoms, including distinctive leaf mosaic patterns and stunted plant growth. Here, transcriptome sequencing revealed that SLCMV infection induced widespread transcriptional reprogramming, with 10,164 differentially expressed genes-6910 up-regulated and 3254 down-regulated. Notably, the down-regulated genes were primarily associated with plant chloroplast components and photosynthesis pathways. Reverse transcription-quantitative PCR analysis confirmed the suppression of key genes involved in photosystem I (PSI) and photosystem II (PSII). Further investigation revealed that SLCMV infection disrupted chloroplast ultrastructure and reduced total chlorophyll content, thereby inhibiting photosynthetic capacity in Nicotiana plants. Importantly, our findings highlighted the critical role of the SLCMV-encoded BC1 protein in repressing photosynthesis-related gene expression and attenuating overall photosynthetic activity. SLCMV-encoded movement protein BC1 down-regulates the expression of photosynthesis-related genes and disrupts chloroplast structure, ultimately leading to reduced photosynthetic activity.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 7","pages":"e70302"},"PeriodicalIF":5.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13311734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148345694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CfSnt2-CfRpd3-Mediated H3 Deacetylation Governs the ROS-Induced Autophagy and Pathogenicity of Colletotrichum fructicola. cfsnt2 - cfrpd3介导的H3去乙酰化调控ros诱导的果糖炭疽菌自噬和致病性

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-07-01 DOI: 10.1111/mpp.70320

Yuan Guo, He Li, Shengpei Zhang

{"title":"CfSnt2-CfRpd3-Mediated H3 Deacetylation Governs the ROS-Induced Autophagy and Pathogenicity of Colletotrichum fructicola.","authors":"Yuan Guo, He Li, Shengpei Zhang","doi":"10.1111/mpp.70320","DOIUrl":"10.1111/mpp.70320","url":null,"abstract":"Reactive oxygen species (ROS) serve as critical immune factors in plants, defending against pathogens infection, but whether pathogenic fungi respond to host-derived ROS through autophagy remains obscure. We previously found that CfSnt2-mediated H3 deacetylation regulates autophagy and responses to oxidative stress in Colletotrichum fructicola, a widespread pathogenic fungus that infects over 50 crops. However, the specific regulatory mechanism is unclear, particularly how oxidative stress is linked to autophagy. Here, we provided evidence that autophagy is highly induced during C. fructicola infection and oxidative stress. We further conducted mass spectrometry analysis of CfSnt2-interacting proteins and identified the histone deacetylase CfRpd3 for functional characterization. We found that CfRpd3 was primarily localized in the nucleus and cooperated with CfSnt2 to regulate the histone H3 deacetylation. Moreover, we demonstrated that both CfRpd3 and CfSnt2 are autophagy repressors that undergo down-regulated expression during ROS-induced autophagy. Targeted gene-deletion of CfRPD3 generated a ΔCfrpd3 mutant that showed defects in growth, conidiation, appressorial formation, and responses to oxidative stress, similar to those observed in the ΔCfsnt2 mutant. These combined effects resulted in their pathogenicity defects. Taken together, our study illustrates a new mechanism by which the CfSnt2-CfRpd3-mediated H3 deacetylation precisely coordinates with autophagy to regulate ROS response and pathogenicity in C. fructicola.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 7","pages":"e70320"},"PeriodicalIF":5.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148549874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ACR3 as a Key Regulator Antimicrobial Lipopeptide Synthesis and Efflux in Bacillus velezensis HN-1. ACR3在velezensis HN-1中作为抗菌脂肽合成和流出的关键调节因子。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70282

Yuying Shen, Jiatong Wang, Ren Zeng, Haonan Wang, Yukai Fang, Zheng Lin, Yu Wang, Wenbo Liu, Qingbiao Xie, Pengfei Jin, Weiguo Miao

{"title":"ACR3 as a Key Regulator Antimicrobial Lipopeptide Synthesis and Efflux in Bacillus velezensis HN-1.","authors":"Yuying Shen, Jiatong Wang, Ren Zeng, Haonan Wang, Yukai Fang, Zheng Lin, Yu Wang, Wenbo Liu, Qingbiao Xie, Pengfei Jin, Weiguo Miao","doi":"10.1111/mpp.70282","DOIUrl":"10.1111/mpp.70282","url":null,"abstract":"Bacillus velezensis is known for producing and secreting antimicrobial lipopeptides, yet the regulatory mechanisms behind these processes remain unclear. In this study, we constructed arsenite transporter protein gene (acr3)-deficient strains (HN-1ΔQ acr3) and complementary strains (HN-1ΔC acr3) to elucidate the roles of ACR3 in antimicrobial lipopeptide synthesis and efflux. Our findings demonstrate that ACR3 dysfunction compromised swarming and biofilm formation, completely abolishing the antifungal capabilities of the HN-1ΔQ acr3 strains. Transcriptomic analysis and reverse transcription-quantitative PCR revealed significant downregulation of lipopeptide biosynthesis genes, including sfp, fenD and bmyC, in HN-1ΔQ acr3. Notably, the addition of purified ACR3 protein restored the expression of lipopeptide biosynthesis genes and partially rescued antifungal activities in the HN-1ΔQ acr3 strains. Furthermore, yeast two-hybrid assays indicated an interaction between ACR3 and proteins involved in cell survival, substrate uptake and antifungal activities, such as ribose ABC transporter substrate-binding protein (RbsB), fengycin synthetases and phosphopantetheine transferases. In parallel, our findings indicate that ACR3 interacts with the ABC transporter pathway to tune antifungal lipopeptide transport in Bacillus velezensis. Collectively, these results suggest that ACR3 functions as a crucial regulator, mediating both the synthesis and efflux of lipopeptides in B. velezensis. These research establish an experimental foundation for elucidating the mechanisms of antimicrobial compound synthesis and secretion in B. velezensis and provide a theoretical basis for the optimisation and engineering of high-yield biocontrol strains.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70282"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13276293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148272219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Copper-Regulated Modulation of the MdbZIP11-MdHAT5 Transcriptional Module Enhances ABA-Mediated Immunity in Apple. 铜调控MdbZIP11-MdHAT5转录模块增强苹果aba介导的免疫

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70297

Hongjia Yu, Zhouzheng Yang, Hanqi Zhou, Chang Geng, Xia Yan, Lili Huang

{"title":"Copper-Regulated Modulation of the MdbZIP11-MdHAT5 Transcriptional Module Enhances ABA-Mediated Immunity in Apple.","authors":"Hongjia Yu, Zhouzheng Yang, Hanqi Zhou, Chang Geng, Xia Yan, Lili Huang","doi":"10.1111/mpp.70297","DOIUrl":"10.1111/mpp.70297","url":null,"abstract":"Transcription factor-mediated integration of hormonal signalling is central to plant immunity, yet how such regulatory modules are activated by external signals in perennial fruit crops remains largely unknown. Here, we show that the effector protein SyCD1 from Saccharothrix yanglingensis Hhs.015 enters apple (Malus domestica) leaf cells and reduces Cu2+ levels, thereby relieving Cu2+-associated repression of the basic leucine zipper transcription factor MdbZIP11. This Cu2+ reduction promotes the accumulation and transcriptional activation of MdbZIP11, enabling downstream activation of abscisic acid (ABA) biosynthesis-mediated immune responses. Mechanistically, MdbZIP11 physically interacts with the ABA-related protein kinase MdSnRK2A, and this interaction is associated with phosphorylation of MdbZIP11 and increased transcriptional activity. MdbZIP11 directly binds to the promoter of the HD-ZIP transcription factor gene MdHAT5, transcriptionally activating its expression; MdHAT5 subsequently functions as a positive regulator of ABA accumulation and disease resistance. Importantly, genetic epistasis analysis confirms that MdHAT5 is indispensable for MdbZIP11-mediated ABA accumulation and disease resistance. Together, our findings uncover a bZIP-HD-ZIP transcription factor relay that amplifies ABA signalling to orchestrate immune responses in apple, providing a conceptual framework for hormone-guided disease resistance in perennial fruit crops.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70297"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13254233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guardians or Gateways? The Intricate Relationship Between Plant Cell Walls and Pathogenic Xanthomonas. 守护者还是门户？植物细胞壁与致病性黄单胞菌的复杂关系。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70292

Charlotte Gaudin, Marie-Agnès Jacques, Nicolas W G Chen

{"title":"Guardians or Gateways? The Intricate Relationship Between Plant Cell Walls and Pathogenic Xanthomonas.","authors":"Charlotte Gaudin, Marie-Agnès Jacques, Nicolas W G Chen","doi":"10.1111/mpp.70292","DOIUrl":"10.1111/mpp.70292","url":null,"abstract":"Plants have evolved a complex cell wall (CW) providing support and protection against environmental constraints, including constant attacks from pests and pathogens. Indeed, the plant CW serves as both a physical barrier and a sophisticated monitoring and signalling system, making it a central component of plant immunity. The Xanthomonas genus encompasses a large diversity of plant-pathogenic bacteria that, together, can infect a wide range of more than 400 plant species including monocots and dicots. Remarkably, Xanthomonas species are subdivided into highly specialized pathovars infecting a narrow range of plant species and/or tissues, each possessing a distinct CW structure and composition. This diversity makes Xanthomonas a perfect case for studying the interactions between bacterial pathogens and the plant CW. In this review, we provide an overview of the intricate interactions between Xanthomonas and the plant CW during the infection process. During infection, Xanthomonas degrades the plant CW both directly by using CW degrading enzymes and indirectly by reprogramming the plant transcriptome to enhance the expression of plant CW modifying enzymes. This degradation of the plant CW plays a central role during infection. On the plant side, it triggers immune responses, while on the Xanthomonas side, it facilitates bacterial invasion and access to nutrients, and activates a signalling hub that primes the pathogen for host colonization.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70292"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148283733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon. P1基因密码子178同源突变对马铃薯y病毒诱导的烟草静脉坏死的抑制作用及其在人干扰素表达中的应用

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70304

De-Guo Liu, Yue-Yue Wang, Qing Zhu, Xin-Wei Huang, Xi-Ying Yan, Meng-Ao Jia, Yu-Shuang Guo, Ling-Gai Cao, Jun Jiang, Xiang-Dong Li, Xiao-Lian Zhang, Yan-Ping Tian

{"title":"Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon.","authors":"De-Guo Liu, Yue-Yue Wang, Qing Zhu, Xin-Wei Huang, Xi-Ying Yan, Meng-Ao Jia, Yu-Shuang Guo, Ling-Gai Cao, Jun Jiang, Xiang-Dong Li, Xiao-Lian Zhang, Yan-Ping Tian","doi":"10.1111/mpp.70304","DOIUrl":"10.1111/mpp.70304","url":null,"abstract":"Plant virus-based vectors are gaining significant attention as bioreactors for recombinant protein production due to their broad host range, robust expression levels and cost-effectiveness; however, their practical utility is frequently constrained by severe viral pathogenicity. Notably, the utility of potato virus Y (PVY), the type member of the genus Potyvirus, is severely hampered by its elicitation of tobacco vein necrosis (TVN). Here, we demonstrate that a single synonymous substitution (AAA to AAG) at the K178 codon of P1 causes almost no TVN. Mechanistically, the P1-AAG mutation attenuates the synergistic RNA silencing suppression (RSS) activity typically mediated by the P1/HC-Pro complex. This functional impairment abrogates the virus-induced upregulation of specific host microRNAs (miR6020, miR6164 and miR6021). Using this non-necrotic PVY-P1-AAG vector, we engineered an optimised bioproduction platform. By integrating a GFP-HRV3C fusion tag system with affinity purification and subsequent proteolytic cleavage, we achieved the high-yield synthesis of recombinant human interferons (IFN-α1b and IFN-α2b) in Nicotiana benthamiana and Nicotiana tabacum 'Xanthi'. Codon optimisation of the cargo genes further enhanced protein accumulation, achieving yields of up to 55.2 μg/g fresh leaf weight. Taken together, these results provide new insights into how synonymous substitutions influence potyviral pathogenicity and validate the symptomless P1-AAG vector as a robust system for biomanufacturing value-added proteins.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70304"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13296828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148318021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter-Strategies. ESCRT：植物免疫和病原体对抗策略的细胞联系。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70298

Willam Kyle Sexton, Shunyuan Xiao

{"title":"ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter-Strategies.","authors":"Willam Kyle Sexton, Shunyuan Xiao","doi":"10.1111/mpp.70298","DOIUrl":"10.1111/mpp.70298","url":null,"abstract":"The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved across all eukaryotic lineages that function in several fundamental cellular processes. Among these are sorting endocytosed membrane proteins, multivesicular body (MVB) biogenesis, and autophagy. Despite the fact that these processes are also critical for plant immune responses, relatively little work has been done studying ESCRT in the context of plant immunity. Several studies indicate that ESCRT influences PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI) by controlling the endosomal sorting of membrane-localized or associated immune signalling components, thereby affecting their localization and stability. Very few studies have examined ESCRT's role in MVB biogenesis during pathogen infection, but because ESCRT drives the formation of MVBs, it is likely involved in all the defence responses MVBs contribute to, such as extracellular vesicle (EV) release and cell wall reinforcement. Similarly, ESCRT's involvement in autophagy during pathogen infection is understudied, but because ESCRT is responsible for phagophore sealing, it is probably required for autophagy's roles in plant immunity, which include its complicated relationship with programmed cell death. ESCRT's relevance to plant immunity is also supported by instances of pathogen effectors targeting ESCRT complexes and evidence suggesting certain ESCRT subunits are monitored by the plant immune system. In this review, we highlight evidence supporting ESCRT's importance in plant immunity, discuss the mechanisms by which ESCRT contributes to immune responses, and identify the major knowledge gaps in this area.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70298"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13280217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The DENN Protein SMD1 Forms a Signalling Hub With Rab GTPase YPT1 to Regulate Diverse Biological Processes in Phytopathogenic Fungi and Serves as a HIGS Target for Crop Protection. DENN蛋白SMD1与Rab GTPase YPT1形成信号中枢，调控植物病原真菌的多种生物过程，并作为作物保护的HIGS靶点。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70289

Cheng Zhang, Lin Li, Sunhong Liu, Yan Xu, Xin Li, Yuelin Zhang

{"title":"The DENN Protein SMD1 Forms a Signalling Hub With Rab GTPase YPT1 to Regulate Diverse Biological Processes in Phytopathogenic Fungi and Serves as a HIGS Target for Crop Protection.","authors":"Cheng Zhang, Lin Li, Sunhong Liu, Yan Xu, Xin Li, Yuelin Zhang","doi":"10.1111/mpp.70289","DOIUrl":"10.1111/mpp.70289","url":null,"abstract":"Sclerotinia sclerotiorum is a notorious necrotrophic plant pathogen that causes severe yield losses in many important crops. Despite its profound economic impact, the molecular mechanisms underpinning its development and virulence processes remain largely elusive. In this study, we characterized a mutant with reduced virulence through a forward genetic screen. Genetic analysis confirmed that mutations in a gene encoding a DENN (Differentially Expressed in Normal cells and Neoplasia) domain-containing protein SsSMD1 (Sclerotia Maturation Deficient 1) led to impaired sclerotia formation and reduced virulence. SsSMD1 affects cell wall integrity and stress tolerance. Notably, SsSMD1 seems to act as a Guanine Nucleotide Exchange Factor (GEF) that interacts with the Rab GTPase SsYPT1. While the knockout of SsYPT1 was lethal, a single amino acid substitution (A136D) in SsYPT1 significantly impaired vegetative growth, sclerotia formation, and virulence. Similarly, knockout analysis in different phytopathogenic fungi revealed that SMD1 homologues were essential for their growth and virulence. We employed host-induced gene silencing (HIGS) targeting SsSMD1 and SsYPT1, which effectively attenuated the virulence of S. sclerotiorum in Nicotiana benthamiana and Arabidopsis thaliana. Collectively, our findings demonstrate that the DENN domain-containing protein is indispensable for development and virulence in major phytopathogenic fungi, and the SsSMD1-SsYPT1 modules can be used as practical HIGS targets against necrotrophic fungal pathogens.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70289"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148176233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Taphrina deformans, the Springtime Scourge of Peach. 探索塔弗瑞娜变形，春天的桃子祸害。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70299

Clotilde Nigon, Morgane Roth, Bénédicte Quilot

{"title":"Exploring Taphrina deformans, the Springtime Scourge of Peach.","authors":"Clotilde Nigon, Morgane Roth, Bénédicte Quilot","doi":"10.1111/mpp.70299","DOIUrl":"10.1111/mpp.70299","url":null,"abstract":"Peach leaf curl, caused by the fungal pathogen Taphrina deformans, is a recurrent disease in peach orchards during spring.Host range: Taphrina deformans infects mostly peach (Prunus persica) and less significantly other Prunus crops.Disease symptoms: Causing severe leaf deformation and massive defoliations, leaf curl can drastically reduce tree vigour and yield and, in severe cases, lead to tree death. To a lesser extent, T. deformans also infects flowers, twigs and fruits.Disease control: Current control strategies rely on preventive fungicide applications including mainly copper-based products.Life cycle: At the end of winter, spores infect young leaves when they emerge from buds. Then, mycelium spreads into intercellular spaces and causes typical deformations. Sporulation of T. deformans at the end of spring spells the end of the mycelium phase. Throughout the rest of the year, spores are budding on the surface of bark and overwinter between the bud scales.Plant-fungus interactions: Infected leaves have a completely disorganized leaf structure and tissues exhibit hyperplastic and hypertrophic cells. T. deformans infection trigger profound metabolic changes whereby multiple plant defence pathways are activated.Conclusion: Knowledge of this pathogen remains surprisingly limited, fragmented and dispersed across decades of literature. The aim of this review is to compile and synthesize existing knowledge to provide for the first time a complete T. deformans life cycle representation while identifying major research gaps. By consolidating existing knowledge and outlining future research priorities, this review aims to stimulate coordinated efforts towards an integrated and sustainable management of peach leaf curl.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70299"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of an Effector-Target Interaction Network for Identification of Immune-Related Effectors in Ralstonia pseudosolanacearum. 假龙葵免疫相关效应物鉴定效应-靶点相互作用网络的构建。

IF 5 1区农林科学

Molecular plant pathology Pub Date : 2026-06-01 DOI: 10.1111/mpp.70280

Bingbing Xue, Yongxiao Xie, Yang Zhang, Wenyan Zhong, Zhuoyuan Tan, Jing Lv, Yongjun Lin, Lifang Ruan

{"title":"Construction of an Effector-Target Interaction Network for Identification of Immune-Related Effectors in Ralstonia pseudosolanacearum.","authors":"Bingbing Xue, Yongxiao Xie, Yang Zhang, Wenyan Zhong, Zhuoyuan Tan, Jing Lv, Yongjun Lin, Lifang Ruan","doi":"10.1111/mpp.70280","DOIUrl":"10.1111/mpp.70280","url":null,"abstract":"Bacterial wilt caused by Ralstonia pseudosolanacearum is a devastating soil-borne disease that results in significant losses of various crops worldwide. The type III secretion system (T3SS) secretes a suite of effectors into host cells, which is a major driver of disease development. These effectors do not act in isolation but form an interconnected network called the effectorome, functioning collectively through extensive crosstalk. Constructing large-scale effector-target interaction networks via high-throughput protein interaction assays is one of the primary approaches to studying effector function at the effectorome level. However, false positives inherent in high-throughput protein interaction methods hinder precise understanding of effector function. Here, we performed Gene Ontology (GO) enrichment analysis on a previously reported large-scale Ralstonia pseudosolanacearum effector-Arabidopsis thaliana target interaction network and found that effectors primarily interact with immune response-related proteins. Subsequently, we validated the interactions between immune-related target proteins and their corresponding effectors using one-to-one yeast two-hybrid assays, generating a validated immune-related effector-target subnetwork. Finally, analyses of reactive oxygen species (ROS) burst, callose deposition, and immune-related gene transcription revealed that the effectors in the subnetwork exhibit immune-suppressive functions, demonstrating the potential of the effector-target network in understanding the pathogenic mechanism at the effectorome level.","PeriodicalId":18763,"journal":{"name":"Molecular plant pathology","volume":"27 6","pages":"e70280"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13250401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0