Minerva dental and oral science最新文献

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Morphometric and radioisotopic analysis of an adult mandibular bone fragment found together with anatomical forceps and two scalpel blades. 与解剖钳和两个手术刀刀片一起发现的成人下颌骨碎片的形态计量学和放射性同位素分析。
IF 1.6
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2025-12-03 DOI: 10.23736/S2724-6329.25.05269-6
Antonio Della Valle, Eleonora Lo Muzio, Caterina Lovece, Lorenzo Lo Muzio, Maria E Bizzoca
{"title":"Morphometric and radioisotopic analysis of an adult mandibular bone fragment found together with anatomical forceps and two scalpel blades.","authors":"Antonio Della Valle, Eleonora Lo Muzio, Caterina Lovece, Lorenzo Lo Muzio, Maria E Bizzoca","doi":"10.23736/S2724-6329.25.05269-6","DOIUrl":"10.23736/S2724-6329.25.05269-6","url":null,"abstract":"<p><strong>Background: </strong>During excavation works for high-speed railway infrastructure in central Italy, at a depth of 430 cm in clayey-gravelly soil, a mandibular bone fragment was discovered together with metal artefacts. The find emerged in the context of geotechnical stabilization works aimed at ensuring ground support for the railway line.</p><p><strong>Methods: </strong>The mandibular fragment, preserved with erupted teeth, was cleaned and analyzed by radiological tomography using software for morphometric and densitometric evaluation. A subsample was examined at a Nuclear Physics Centre for radioisotopic dating and to assess the individual's physical and nutritional status at the time of death. Comparative archaeological analyses were performed to identify the nature and chronology of the associated metal artefacts.</p><p><strong>Results: </strong>Morphometric assessment confirmed the remains belonged to an adult primate of the Order Eutheria, with traits consistent with a human specimen. Radiological and isotopic studies yielded data on bone density, preservation, and temporal context. The artefacts displayed distinct morphological features attributable to manufactured tools. Archaeological comparison indicated they were most likely the tips of surgical instruments, dating to the Roman period (first century AD).</p><p><strong>Conclusions: </strong>This multidisciplinary investigation demonstrates the value of combining morphometric, radiological, radioisotopic, and archaeological analyses in reconstructing the biological and cultural significance of osteological finds. The evidence suggests the mandibular fragment belonged to an adult individual, and the associated artefacts can be interpreted as surgical instruments from the Roman era, providing rare insights into ancient medical practices.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"78-97"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral superior labial artery embolization for arteriovenous malformation. 双侧唇上动脉栓塞治疗动静脉畸形。
IF 1.4
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2026-01-19 DOI: 10.23736/S2724-6329.25.05169-1
Carlo Fornaseri, Ylenia Gugliotta, Alberto Balderi, Giovanni Gerbino, Marco Bernardi
{"title":"Bilateral superior labial artery embolization for arteriovenous malformation.","authors":"Carlo Fornaseri, Ylenia Gugliotta, Alberto Balderi, Giovanni Gerbino, Marco Bernardi","doi":"10.23736/S2724-6329.25.05169-1","DOIUrl":"10.23736/S2724-6329.25.05169-1","url":null,"abstract":"<p><p>Lip arteriovenous malformations (AVMs) are typically present at birth and can lead to progressive tissue destruction and functional and cosmetic issues. Their management is challenging due to the lack of standardized protocols and may involve both surgical and non-surgical approaches. The authors present a case of upper lip AVM with feeders bilaterally from both facial arteries and their superior labial branch arteries. Bilateral Gelfoam embolization of the labial arteries followed by surgical resection was performed. The upper lip was reconstructed using a bilateral advancement flap. The patient's intraoperative and postoperative courses were uneventful, and no recurrence was recorded. The functional and aesthetic results were good and satisfying for the patient at the 1-year follow-up. Upper lip AVMs can be managed through a combination of presurgical embolization and complete surgical resection. The use of a rapidly absorbable embolic material does not compromise the surgical resection procedure and reduces the risk of complications such as necrosis of the upper lip, especially in cases where it is necessary to embolize both upper labial arteries.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"152-159"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of robot-assisted UV disinfection in dentistry. 机器人辅助紫外线消毒在牙科中的应用。
IF 1.4
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2024-09-11 DOI: 10.23736/S2724-6329.23.04866-0
Vini Mehta, Visha S Pandya, Ankita Mathur, Vishnu T Obulareddy, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini
{"title":"Applications of robot-assisted UV disinfection in dentistry.","authors":"Vini Mehta, Visha S Pandya, Ankita Mathur, Vishnu T Obulareddy, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.23.04866-0","DOIUrl":"10.23736/S2724-6329.23.04866-0","url":null,"abstract":"<p><p>Maintaining a microbial-free environment in healthcare facilities is more widely recognized as an essential component of therapies to minimize transmission of viruses associated with healthcare sector. The global spread of COVID-19 and recent outbreaks have presented humanity with previously unheard-of challenges. The development of autonomous disinfection robots seems to be necessary given the urgent need for constant sterilization in the face of a labor shortage. Due to their automated and perceived cost advantages by eliminating cleaning staff, these robots are being advertised more and more as an easy solution to immediately disinfect rooms and operating areas. The use of these services lowers the danger of infection, and expense of traditional cleaning and, most significantly, builds trust and security in medical facilities. Currently, routine (manual) cleaning is not replaced by disinfection robots; rather, they may support it. Additional hospital and device design alterations are necessary to address the overshadowing (visibility) issue allowing Ultraviolet disinfectant (UV-D) robots move freely in the medical environment. More technical developments and clinical studies in a variety of hospitals are needed to overcome the current challenges and find ways to integrate this unique technology into hospitals now and in the future. Thus, we present a review that includes detailing all elements required for it to function, as well as both its advantages and disadvantages. To the best of our knowledge, very limited studies have collected an in- depth data on the sterilization effect using a disinfection robot in the field of dentistry. We believe that this data will work as a foundation in more advanced uses at diverse sites that require disinfection and will highlight unsolved challenges and potential research avenues for UV robot operational concerns in dental hospitals. The goal of this work is to offer a comprehensive manual for UV-D robots covering pertinent information on traditional Ultraviolet germicidal irradiation (UVGI) system along with advancements in UV-D robots and thereby focusing on in-depth application in medical and dental facilities.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"139-151"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142291439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of possible complications associated with direct composite restorations: a systematic review. 对直接复合修复相关并发症的认识:一项系统综述。
IF 1.4
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2026-02-04 DOI: 10.23736/S2724-6329.25.05264-7
Kacper Nijakowski, Marta Mazur, Jakub Handschuh, Anna Lehmann
{"title":"Awareness of possible complications associated with direct composite restorations: a systematic review.","authors":"Kacper Nijakowski, Marta Mazur, Jakub Handschuh, Anna Lehmann","doi":"10.23736/S2724-6329.25.05264-7","DOIUrl":"10.23736/S2724-6329.25.05264-7","url":null,"abstract":"<p><strong>Introduction: </strong>Resin-based composites (RBCs) are among the most widely used materials for direct dental restorations due to their aesthetics and conservative preparation requirements. However, their clinical application remains highly technique-sensitive, and long-term outcomes are frequently compromised by complications. This systematic review aimed to evaluate the most common clinical challenges associated with direct composite restorations and assess awareness of these complications among dentists, dental students, and patients.</p><p><strong>Evidence acquisition: </strong>A comprehensive search of PubMed, Scopus, Web of Science, and Embase was conducted for studies published between January 2010 and August 2025, following PRISMA guidelines. Twenty eligible studies were included, encompassing survey-based research, clinical follow-ups, and cross-sectional analyses across diverse populations. Quality assessment revealed methodological heterogeneity, with most studies rated as intermediate quality.</p><p><strong>Evidence synthesis: </strong>The most frequently reported complications included secondary caries, restoration fractures, marginal defects, postoperative hypersensitivity, and food impaction. Factors contributing to these failures were multifactorial, encompassing operator technique, material properties such as polymerization shrinkage and moisture sensitivity, patient-related behaviors including poor oral hygiene and parafunctional habits, and inadequate pre- and postgraduate training. Evidence further indicated that repair, rather than replacement, is often a conservative and effective management strategy.</p><p><strong>Conclusions: </strong>The success of composite restorations depends not only on material advancements but also on clinician skill, adherence to evidence-based protocols, and patient cooperation. Continuous professional education and preventive measures remain critical for reducing complications and improving restoration longevity.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"98-109"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of the bone remodeling of implant with convergent neck walls positioned at the crestal and subcrestal levels. 会聚颈壁位于牙冠和牙下水平种植体骨重塑的比较评价。
IF 1.4
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2026-02-04 DOI: 10.23736/S2724-6329.25.05147-2
Daniele Viscardi, Fabio Carini, Ayt Alla Bader, Fabrizio Carini, Gianluca Porcaro
{"title":"Comparative evaluation of the bone remodeling of implant with convergent neck walls positioned at the crestal and subcrestal levels.","authors":"Daniele Viscardi, Fabio Carini, Ayt Alla Bader, Fabrizio Carini, Gianluca Porcaro","doi":"10.23736/S2724-6329.25.05147-2","DOIUrl":"10.23736/S2724-6329.25.05147-2","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to evaluate the bone remodeling of implant with convergent neck walls positioned at the crestal and subcrestal levels. The remodeling of the bone and soft tissue is influenced by the surgical and restorative techniques and by the materials used.</p><p><strong>Methods: </strong>The study analyzed 128 patients with 262 implants, comparing subcrestal (Site A) and crestal (Site B) placements. Radiographic evaluations at T0 and T1 (12 months) were used to collect standardized clinical data on oral conditions and implant stability.</p><p><strong>Results: </strong>The success rate with implant osseointegration at 12 months was 100% in both groups. The discrepancy between the two bone remodeling averages, 12 months apart, in implants positioned at level A and implants positioned at level B, is minimal. The average between the mesial and distal bone remodeling for implants positioned at level A is -0.854 mm T1-T0 mesial and -0.512 mm distal and for implants positioned at level B is -0.45 mm T1-T0 mesial and -0.69 mm T1-T0 distal.</p><p><strong>Conclusions: </strong>The search for possible radiographic differences between the crestal and subcrestal positioning of the convergent neck implants, concludes by observing the lack of a statistically significant result but with important insights into the positioning method at level B. The average bone loss is favorable for crestal positioning (-0.57 mm) compared to subcrestal (-0.683 mm).</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"67-77"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of skeletal stability between single plate osteosynthesis and double plate osteosynthesis in anterior mandibular osteotomies: a randomized case-control trial. 单钢板与双钢板在前颌骨截骨术中骨骼稳定性的比较:一项随机病例对照试验。
IF 1.4
Minerva dental and oral science Pub Date : 2026-04-01 Epub Date: 2026-01-22 DOI: 10.23736/S2724-6329.25.05125-3
Raparthy B Chandra, Sneha Pendem, Kathiravan Selvarasu, Pratyusha Vundemodelu, Marimuthu R Muthusekhar
{"title":"Comparison of skeletal stability between single plate osteosynthesis and double plate osteosynthesis in anterior mandibular osteotomies: a randomized case-control trial.","authors":"Raparthy B Chandra, Sneha Pendem, Kathiravan Selvarasu, Pratyusha Vundemodelu, Marimuthu R Muthusekhar","doi":"10.23736/S2724-6329.25.05125-3","DOIUrl":"10.23736/S2724-6329.25.05125-3","url":null,"abstract":"<p><strong>Background: </strong>The aim of the current study is to compare the skeletal stability of single-plate versus double-plate osteosynthesis in anterior mandibular osteotomies.</p><p><strong>Methods: </strong>A prospective case-control trial was planned, enrolling all the patients who reported to us for the correction of anterior mandibular issues, including patients planned for lower anterior sub-apical osteotomies and genioplasties. The patients were randomly allocated to two groups Group I (single plate fixation) and Group II (two plate fixation) based on the Lot method. The patients in each group were further divided into subgroups, with Subgroup A undergoing subapical setback and Subgroup B undergoing advancement genioplasty. All the patients underwent preoperative clinical and cephalometric evaluation (T1) to assess the magnitude of movement of the anterior mandibular segments. All the patients had an immediate post-operative cephalogram done (T2). They were under follow-up for 6 months to 3 years (T3), and the post-operative skeletal stability was assessed using COGS analysis on a lateral cephalogram between T3 and T2. Intraoperative time and postoperative neurosensory disturbances were the secondary outcomes that were measured. G power analysis was used to calculate the sample size, and statistical analysis used SPSS (version 23.0), employing ANCOVA for non-parametric tests (Quade's approach) with significance set at P<0.05.</p><p><strong>Results: </strong>Twenty-six patients within the age group of 15 to 35 years (14 females, 12 males) were enrolled in the study. Thirteen patients were allocated to each group. Seven patients underwent genioplasty in group I and seven in group II, and six underwent subapical osteotomy in groups I and six in group II, respectively. The mean magnitude of subapical setback was 7 mm, while the magnitude of chin advancement was 8 mm, and this was comparable among the groups. The cephalometric evaluation involved the evaluation of vertical and horizontal distances of points B, Pog, and menton from the true horizontal and true vertical of COGS analysis. These parameters showed no statistically significant differences in the follow-up period (T3-T2) between single-plate and double-plate osteotomy groups for subapical osteotomies and genioplasties between age and sex-matched control groups. However, secondary outcomes, including neurosensory disturbances, intraoperative time, differed significantly (P<0.05) between groups and favored the use of single plate fixation.</p><p><strong>Conclusions: </strong>This clinical trial suggests that the choice between single-plate and double-plate osteosynthesis does not significantly affect skeletal stability following anterior mandibular osteotomies. However, significant differences were observed in secondary outcomes, indicating potential considerations for surgical approach in orthognathic procedures.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"59-66"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the dental sector on the environmental pollution: an overview. 牙科行业对环境污染的影响:综述。
IF 1.6
Minerva dental and oral science Pub Date : 2026-02-01 Epub Date: 2025-09-09 DOI: 10.23736/S2724-6329.25.05152-6
Fulvia Galletti, Cesare D'Amico, Cosimo Galletti, Gabriele Cervino, Vini Mehta, Luca Fiorillo
{"title":"Impact of the dental sector on the environmental pollution: an overview.","authors":"Fulvia Galletti, Cesare D'Amico, Cosimo Galletti, Gabriele Cervino, Vini Mehta, Luca Fiorillo","doi":"10.23736/S2724-6329.25.05152-6","DOIUrl":"10.23736/S2724-6329.25.05152-6","url":null,"abstract":"<p><p>Dental waste, including metal, plastic, and chemical residues, and high energy and water consumption, significantly contribute to environmental degradation. This review highlights the environmental impact of common dental materials and practices, such as amalgam, resin composites, and disposable plastics. The aim is to examine current evidence, emphasizing mercury pollution, microplastic release, and biomedical waste handling. Moreover, it explores the emerging concept of green dentistry and provides an overview of international regulatory efforts. The paper advocates for sustainable practices in dentistry through prevention, innovation, and informed clinical choices, supported by life cycle assessment approaches.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"51-56"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dense polytetrafluoroethylene (dPTFE) membranes for alveolar ridge preservation: a comprehensive clinical review. 密集聚四氟乙烯(dPTFE)膜用于牙槽嵴保存:一个全面的临床回顾。
IF 1.6
Minerva dental and oral science Pub Date : 2026-02-01 Epub Date: 2025-11-19 DOI: 10.23736/S2724-6329.25.05244-1
Georgios S Chatzopoulos
{"title":"Dense polytetrafluoroethylene (dPTFE) membranes for alveolar ridge preservation: a comprehensive clinical review.","authors":"Georgios S Chatzopoulos","doi":"10.23736/S2724-6329.25.05244-1","DOIUrl":"10.23736/S2724-6329.25.05244-1","url":null,"abstract":"<p><strong>Introduction: </strong>Alveolar ridge preservation (ARP) is a critical procedure to mitigate bone resorption following tooth extraction. This review comprehensively evaluates the current evidence on the use of dense polytetrafluoroethylene (dPTFE) membranes for ARP, assessing their efficacy in maintaining ridge dimensions and promoting tissue regeneration to facilitate future implant placement.</p><p><strong>Evidence acquisition: </strong>A comprehensive review of the literature was conducted using databases including PubMed/MEDLINE, Embase, and the Cochrane Library. Evidence was gathered from various study designs, including randomized controlled trials, cohort studies, and case series that investigated the use of dPTFE membranes, both alone and in conjunction with bone grafts.</p><p><strong>Evidence synthesis: </strong>The evidence consistently demonstrates that dPTFE membranes effectively preserve alveolar ridge dimensions. The \"open membrane\" technique, where the dPTFE is intentionally left exposed, is shown to be a predictable approach that enhances keratinized tissue width with minimal complications. Histological analyses confirm reliable vital bone formation, with outcomes influenced by healing duration and graft material selection. Furthermore, dPTFE membranes have proven effective in managing complex situations, including compromised sockets and oroantral communications.</p><p><strong>Conclusions: </strong>Dense polytetrafluoroethylene membranes represent a versatile and effective modality for alveolar ridge preservation. Their application, particularly with the open membrane technique, reliably maintains hard and soft tissue architecture, creating favorable conditions for subsequent dental implant rehabilitation.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"27-35"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploration of four digital oral examination instruments. 四种数字式口腔检查仪器的探索。
IF 1.6
Minerva dental and oral science Pub Date : 2026-02-01 Epub Date: 2025-11-19 DOI: 10.23736/S2724-6329.25.05148-4
Jing Kang, Yue Wang
{"title":"Exploration of four digital oral examination instruments.","authors":"Jing Kang, Yue Wang","doi":"10.23736/S2724-6329.25.05148-4","DOIUrl":"10.23736/S2724-6329.25.05148-4","url":null,"abstract":"","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"57-58"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of bone adhesives in bone regeneration: a comprehensive review of clinical applications and outcome. 骨胶粘剂在骨再生中的应用:临床应用和结果的综合综述。
IF 1.6
Minerva dental and oral science Pub Date : 2026-02-01 Epub Date: 2025-10-29 DOI: 10.23736/S2724-6329.25.05212-X
Alessio Rosa, Paolo Barnaba, Marco Gargari, Mirko Martelli
{"title":"The use of bone adhesives in bone regeneration: a comprehensive review of clinical applications and outcome.","authors":"Alessio Rosa, Paolo Barnaba, Marco Gargari, Mirko Martelli","doi":"10.23736/S2724-6329.25.05212-X","DOIUrl":"10.23736/S2724-6329.25.05212-X","url":null,"abstract":"<p><p>Bone adhesives have emerged as a promising adjunct in regenerative medicine due to their potential to enhance fixation, improve osteointegration, and reduce operative time. Their application is particularly relevant in scenarios where traditional mechanical fixation is challenging or invasive, such as in cranial, orthopedic, and maxillofacial procedures. This narrative review explores the current landscape of bone adhesives, with a focus on synthetic and bioadhesive composites. A literature search was conducted across PubMed, Scopus, and Web of Science, including both preclinical and clinical studies published in the last two decades. Key parameters analyzed include adhesive composition, mechanical strength, biocompatibility, degradation behavior, and clinical outcomes. The reviewed evidence highlights that bone adhesives exhibit promising properties for use in bone regeneration. Synthetic adhesives, such as cyanoacrylates and polyurethane-based glues, offer high initial bond strength, while bioadhesives - often based on fibrin, collagen, or dopamine-functionalized polymers - demonstrate superior biocompatibility and osteoconductive potential. Clinical studies suggest their utility in bone graft stabilization, cranial defect repair, and minimally invasive maxillofacial surgery. Additionally, adhesives have been shown to reduce the need for hardware fixation, lower infection risks, and promote faster recovery. Bone adhesives represent a valuable complementary tool in regenerative bone procedures. While their integration into clinical practice is still evolving, current data support their safety and efficacy in selected surgical contexts. Further large-scale, long-term trials are warranted to validate their performance and optimize material formulations for specific applications.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"43-50"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145391498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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