Vritika Singh, Reema Sharma, Nikhil Marwah, Vipul Sharma, Maria Maddalena Marrapodi, Gabriele Cervino, Giuseppe Minervini
{"title":"Is there a correlation between A, B, and O blood group system and dental anxiety in pediatric dental patients? An observational study.","authors":"Vritika Singh, Reema Sharma, Nikhil Marwah, Vipul Sharma, Maria Maddalena Marrapodi, Gabriele Cervino, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.05064-2","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05064-2","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and fear are significant challenges in pediatric dentistry, often leading to avoidance of dental treatment. Some studies suggest a potential link between the dopamine beta-hydroxylase gene and the ABO gene. As ABO blood group type is determined genetically, it could serve as a bioindicator for assessing the impact of genetics on personality traits. The association between blood types and personality characteristics has long been debated.</p><p><strong>Methods: </strong>Eighty eligible children, meeting the inclusion criteria, were enrolled in the study. Blood group data were obtained from parents/guardians. Dental anxiety assessment was done using the RMS-Picture scale and pulse oximeter.</p><p><strong>Results: </strong>The collected data were analyzed statistically.</p><p><strong>Conclusions: </strong>The study found no correlation between dental anxiety and ABO blood grouping.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilser Turkyilmaz, Johari Y Abdullah, Gregory N Wilkins, Sara Bernardi, Giuseppe Varvara
{"title":"Analysis of the effects of mesh reduction of digital files on the surface area and volume accuracy of complete dentures using an intraoral scanner.","authors":"Ilser Turkyilmaz, Johari Y Abdullah, Gregory N Wilkins, Sara Bernardi, Giuseppe Varvara","doi":"10.23736/S2724-6329.24.04898-8","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04898-8","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to determine the accuracy of an intraoral scanner to digitally duplicate complete dentures and analyze the effects of mesh reduction of digital files on the surface area and volume accuracy of complete dentures, in vitro.</p><p><strong>Methods: </strong>A mandibular complete denture was scanned by a desktop scanner to create a digital STL reference file (control). Fifteen identical scans were created by using an intraoral scanner and exported as STL files (test group). These 15 files were saved at 100% of the original scan resolution then reduced to 75%, 50%, 25%, and 10% of their original quality. These 75 scans were statistically analyzed by calculating The Hausdorff Distance (HD) and Dice Similarity Coefficients (DSC) to assess the variation between the mean reduced intraoral scanner files test and the control desktop scanner file and eventual inconsistencies. The volumes of the reduced mesh files were also compared with the 100% resolution intraoral mesh files to evaluate precision and trueness of the intraoral scanner.</p><p><strong>Results: </strong>Reduced mesh files of 10%, 25%, 50%, 75% of the original scan yielded a percentage similarity average of 99.7%, indicating a very high precision value for the intraoral scanner. Also, the volumes of each associated mesh reduction slightly decreased with non-statistically significant results.</p><p><strong>Conclusions: </strong>This study concluded that the chosen intraoral scanner for this study provided very high trueness (98.34%) and precision (99.7%), and also the volumes of reduced mesh files slightly decreased but were not statistically significant.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hafiz A Adawi, Saurabh Jain, Ahmed O Shami, Hamood M Mahdali, Ali M Kaabi, Osama B Balki, Marco Cicciù, Giuseppe Minervini
{"title":"Evaluation of the effect of aging on the shear bond strength between old composite resin restoration and the repair composite resin: an in-vitro study.","authors":"Hafiz A Adawi, Saurabh Jain, Ahmed O Shami, Hamood M Mahdali, Ali M Kaabi, Osama B Balki, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04889-7","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04889-7","url":null,"abstract":"<p><strong>Background: </strong>The current study aimed to evaluate the effect of aging on the repair bond strength between old composite resin and repaired composite resin and to evaluate which type of repair composite material provides better bond strength in different time durations.</p><p><strong>Methods: </strong>Eighty nano-hybrid composite specimens were randomly divided into four groups (N.=20) and exposed to accelerated aging from 0 to 2 years. Each group was further divided into two subgroups, A and B, repaired with packable and flowable composite respectively, after micro-abrasion treatment. Shear bond strength was assessed and statistically analyzed.</p><p><strong>Results: </strong>It was observed that with an increase in aging time, the bond strength of both the composite materials used for repair decreased. The flowable composite's mean bond strength (22.09±0.65, 18.74±2.36, and 17.74±2.38 MPa) was more than the packable composite (21.97±0.84, 17.97±3.85, and 15.97±2.45 MPa) used for repair on aged specimens. In contrast, the bond strength of the packable was more than the flowable composite in control group specimens that were not aged (23.25±0.89 vs. 22.40±1.26).</p><p><strong>Conclusions: </strong>As restored composites age, their bond strength decreases. Flowable composite displays better repair shear strength than packable composite as aging progresses. Micro abrasion followed by flowable composite bonding can repair aged composite restorations effectively.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pradeep K Yadalam, Jeevitha Manickavasagam, Trisha Sasikumar, Maria M Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini
{"title":"AI-based prediction and classification of root caries using radiographic images.","authors":"Pradeep K Yadalam, Jeevitha Manickavasagam, Trisha Sasikumar, Maria M Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04967-2","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04967-2","url":null,"abstract":"<p><strong>Background: </strong>Root surface caries, commonly known as root decay, is a common dental disorder that affects tooth roots. Like enamel-based tooth decay, root caries attack exposed root surfaces caused by gum recession or periodontal disease. Older persons with gum recession, tooth loss, or poor oral hygiene may be more likely to develop this disorder. Dental root caries must be diagnosed early to improve treatment and prevention. This research will examine radiographic image-based AI-based root caries prediction algorithms.</p><p><strong>Methods: </strong>Saveetha Dental College supplied 200 root surface radiographs. An expert dentist and dental radiologist confirmed one hundred teeth with root caries and 100 without. Edited and segmented radiographic images. Orange, a machine learning squeeze net embedding model with Naive Bayes, Logistic Regression, and neural networks, was used to assess prediction accuracy. Training and test data were split 80/20. Cross-validation, confusion matrix, and ROC analysis assessed model performance. This study examined precision and recall.</p><p><strong>Results: </strong>Naïve bayes and logistic regression have 96% and 100% accuracy, but class accuracy is -94% and 100% in image classification of root caries was seen.</p><p><strong>Conclusions: </strong>AI-based root caries prediction utilizing radiographic images would improve dental care by diagnosing and treating early, accurately, and personalized. With appropriate deployment, research, and ethics, AI integration in dentistry could benefit practitioners and patients. Dental professionals and AI experts must work together to maximize this new technology.AI integration in dentistry can significantly improve root caries diagnosis and treatment by predicting root caries using radiographic images. This early detection reduces treatment need and time. Collaboration between dental professionals and AI experts is crucial for maximizing benefits.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Caroccia, Jovana Juloski, Jelena Juloski, Patrizia Marti, Flavio Lampus, Alessandro Vichi, Veronica Giuntini, Valentina Rutili, Michele Nieri, Cecilia Goracci, Lorenzo Franchi
{"title":"3D printed customized facemask for early treatment of Class III malocclusion: a two-center case series feasibility study.","authors":"Francesco Caroccia, Jovana Juloski, Jelena Juloski, Patrizia Marti, Flavio Lampus, Alessandro Vichi, Veronica Giuntini, Valentina Rutili, Michele Nieri, Cecilia Goracci, Lorenzo Franchi","doi":"10.23736/S2724-6329.24.05013-7","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05013-7","url":null,"abstract":"<p><strong>Background: </strong>This prospective two-center case series feasibility study aimed to investigate the potential of a novel maxillary protraction facemask customized to the patients' anatomy recorded with 3D face scanning and then produced by digital design and additive manufacturing.</p><p><strong>Methods: </strong>Ten subjects (5 females and 5 males, average age 7.7±1.0 years) with Class III malocclusion were treated with a rapid maxillary expander (RME) and a Petit-type facemask (FM), whose components were digitally designed on a 3D scan of the patient's face. Subjects' face scans were obtained either with a tablet or with face scanner. FM components were modelled with a 3D software. The pads were 3D printed in biocompatible resin, and the bar was printed in stainless steel. A questionnaire investigating the patients' experience was filled in after the first week of treatment and after 3, 6, and 9 months.</p><p><strong>Results: </strong>The customized FM showed an excellent adaptation to the anatomy of the face. No severe complications were reported during the 9 months of appliance wearing. Some reversible episodes of skin irritation were reported below the pads, mainly in the chin area. The reported time wearing ranged between 8.2±2.3 and 9.5±1.2 hours per day, mainly at night. Reported pain was overall low (maximum after 1 week with an average value of 1.9±1.7 on a visual analog scale [VAS] 0-10) and patients' satisfaction was adequate at the end of the facemask wear after 9 months (8.7±1.4 on a VAS 0-10).</p><p><strong>Conclusions: </strong>The customized FM was overall well accepted by the patients and represents a valid alternative to conventional ones.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniele Cardaropoli, Lorenzo Tamagnone, Luigi Laino, Lorena Gaveglio
{"title":"Early wound healing in guided bone regeneration procedures using sodium hyaluronate and a pool of amino acids: a randomized clinical trial.","authors":"Daniele Cardaropoli, Lorenzo Tamagnone, Luigi Laino, Lorena Gaveglio","doi":"10.23736/S2724-6329.24.05095-2","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05095-2","url":null,"abstract":"<p><strong>Background: </strong>Soft tissue healing is of paramount importance when guided bone regeneration techniques are used, as early exposure of the membrane could affect the results.</p><p><strong>Methods: </strong>In this randomized clinical trial, enrolling 20 patients, a gel rich in hyaluronic acid and amino acids was used to promote wound healing after a ridge augmentation procedure. The Early Wound Healing Index - EHS was used to assess soft tissue healing by primary intention following surgery at 1, 3, 7 and 14 days.</p><p><strong>Results: </strong>Results showed faster tissue healing when hyaluronic acid mixed with amino acids was used, and also a lower perception of pain by patients measured with a VAS scale.</p><p><strong>Conclusions: </strong>These data suggest the creation of larger research studies that can support the use of biologics for early soft tissue healing.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kavithaa Rajasekaran, Kaviyarasi Renu, Kavitha Sankaran, Vishnu Priya Veeraraghavan, Gayathri Rengasamy, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini
{"title":"Determination of red blood cell parameters for signs of iron deficiency anemia in patients with oral diseases.","authors":"Kavithaa Rajasekaran, Kaviyarasi Renu, Kavitha Sankaran, Vishnu Priya Veeraraghavan, Gayathri Rengasamy, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04907-6","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04907-6","url":null,"abstract":"<p><strong>Background: </strong>A lack of healthy red blood cells such as iron deficiency frequently consequences as anemia. In expectant women, iron deficiency increases the risk of developmental delays in the fetus. It is utilized to regenerate red blood cells (RBC), which determines the storage and transport of oxygen in the body. As for oral symptoms and indications, it has an inclusive of atrophic glossitis, oral mucosa atrophy, and oral mucosa tenderness or a sensation with burning in mouth. The objective is to determine RBC parameters for iron deficiency anemia (IDA) symptoms in oral disease patients.</p><p><strong>Methods: </strong>Normal and oral disease patients' blood is collected in a 2-mL EDTA vial for the hematology analyzer. With file number SRB/SDC/UG-2155/22/493, the institutional ethical approval committee approved this study: 10 controls (without anemia) and 10 patients with oral disease (with anemia).</p><p><strong>Results: </strong>In oral disease patients with anemia, a decreased hemoglobin level is observed. In this study, nearly all anemic patients have IDA. In IDA, the RBC count decreases, the MCV decreases, the MCH decreases, and the RDW rises. We have analyzed various iron deficiency anemia indices. Ricercari and Eshani demonstrate a significant change in it.</p><p><strong>Conclusions: </strong>In predicting iron deficiency anemia, our results indicate that oral patients have significant differences in hematological parameters that are individual. It demonstrates that oral disease patients are developing iron deficiency anemia than controls (healthy). Additionally, the discrimination indices reveal that they do not have hemoglobinopathies but rather iron deficiencies. Oral manifestations are more prevalent in Iron deficiency anemia (IDA) patients than in healthy patients, according to our findings.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afrah A Aldelaimi, Hamid H Enezei, Thamer Y Humadi, Khalil A Mohammed, Tahrir N Aldelaimi, Maria M Marrapodi, Gabriele Cervino, Giuseppe Minervini
{"title":"The pyogenic granuloma: localization, incidence, clinical features.","authors":"Afrah A Aldelaimi, Hamid H Enezei, Thamer Y Humadi, Khalil A Mohammed, Tahrir N Aldelaimi, Maria M Marrapodi, Gabriele Cervino, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.05075-7","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05075-7","url":null,"abstract":"<p><strong>Background: </strong>A pyogenic granuloma (PG) represents a swiftly proliferating benign vascular tumor situated in the skin or subcutaneous tissue, commonly observed as a reactive lesion in the orofacial area. This research intended to scrutinize the clinicopathological characteristics of pyogenic granulomas in the oral and maxillofacial region.</p><p><strong>Methods: </strong>Seventy two participants, comprising 24 men (33%) and 48 women (67%), underwent surgical ablation of pyogenic granuloma in oral and maxillofacial regions utilizing 940nm and 980nm diode lasers. Standard tissue processing procedures were applied to all specimens, with subsequent slicing of paraffin-embedded blocks at a 5µm thickness for H & E staining. A microscopic examination via light microscopy was conducted on all slides to confirm the diagnosis.</p><p><strong>Results: </strong>All cases underwent pyogenic granuloma surgical laser ablation, with 53 individuals (74%) aged 30 years or younger, 19 (26%) aged 30 years or more, 52 (72%) have duration less than six months,, and 20 (28%) have a six months or more.</p><p><strong>Conclusions: </strong>Pyogenic granuloma emerges as a prevalent reactive lesion in the oral and maxillofacial domain. The diode laser demonstrates utility in oral and facial soft tissue surgery owing to its facile application, enhanced coagulation, avoidance of suturing, reduced swelling and pain, and its capacity for esthetically favorable outcomes, encompassing superior de-epithelialization, absence of bleeding, and improved repair. The roles of surgeons and pathologists are pivotal in diagnosing and treating pyogenic granuloma in oral and maxillofacial regions.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jai P Rexlin, Jeevitha Manickavasagam, Pradeep K Yadalam, Deepti Shrivastava, Kumar C Srivastava, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini
{"title":"In-silico immunoinformatic vaccine design for Treponema denticola ergothionase.","authors":"Jai P Rexlin, Jeevitha Manickavasagam, Pradeep K Yadalam, Deepti Shrivastava, Kumar C Srivastava, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04915-5","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04915-5","url":null,"abstract":"<p><strong>Background: </strong>Treponema denticola, a well-studied oral spirochete, adheres, invades, and damages periodontal tissues - gram-negative, anaerobic Treponema denticola. In previous research, sub-gingival spirochetes have correlated positively with dental plaque score, pocket, and clinical attachment level measurements. Hence, the study aims to design an immunoinformatic vaccine using a reverse vaccinology approach against Treponema denticola ergothionase.</p><p><strong>Methods: </strong>Protein Data Bank provided the FASTA amino acid sequence of Treponema denticola. Antigenicity, toxicity, and stability of discovered T-cell epitopes were evaluated to develop 6S7Q B and A multiepitope vaccination design. The Vaccine's dual major histocompatibility complex (MHC I and II) binding epitopes were also predicted. The designed Vaccine's identified epitope sequence and secondary structure were then predicted and validated. Protein-protein interactions involving ergothionase and human beta-defensins were investigated using molecular docking.</p><p><strong>Results: </strong>The designed Vaccine had high antigenicity, toxicity, and stability. The Vaccine's three-dimensional structure demonstrated a significant association with beta-defensin. Its low binding energy score of -827.6 kcal/mol indicates that the immune system will respond favorably to the antigen.</p><p><strong>Conclusions: </strong>In this research, we employed immunoinformatic techniques to create a reverse vaccination effort to develop an in-silico vaccine.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessio Rosa, Riccardo DE Angelis, Alberto M Pujia, Pierluigi Cardelli, Claudio Arcuri
{"title":"Virtual reality in specialized dentistry: employing virtual reality for the alleviation of pain and anxiety in hereditary angioedema patients.","authors":"Alessio Rosa, Riccardo DE Angelis, Alberto M Pujia, Pierluigi Cardelli, Claudio Arcuri","doi":"10.23736/S2724-6329.24.04961-1","DOIUrl":"10.23736/S2724-6329.24.04961-1","url":null,"abstract":"<p><strong>Background: </strong>Following an episode of hereditary angioedema (HAE), dental anxiety commonly arises, and many patients find it challenging to access proper care. While the use of virtual reality (VR) for pain and anxiety management in dentistry is on the rise, its application in individuals with angioedema remains largely unexplored. In a case series conducted at a specialized dental clinic, three patients with a history of acute angioedema attacks and dental anxiety engaged with 360° VR videos while seated in the dental chair, utilizing a virtual reality device.</p><p><strong>Methods: </strong>Three patients with hereditary angioedema were treated by subjecting them to virtual immersion using VR glasses. Intraoperative reactions were analyzed using VAS scales in order to report the patients' level of anxiety and pain.</p><p><strong>Results: </strong>The outcomes, evaluated through a standard observation tool, surveys, and interviews, encompass the assessment of patient anxiety and pain, responses to VR, and the evaluation of system usability along with its impact on the dental team's workflow Three individuals underwent examination, from which three reliable questionnaires were obtained, demonstrating a success rate of 99.9%. The group included one male and two females, with their ages spanning from 6 to 58 years. The findings revealed an average anxiety score of 1.80 with a standard deviation of 0.6 points, and an average pain score of 1.98 with a standard deviation of 0.3, thus validating full immersion in distraction. Statistical analysis using independent-sample t-tests and ANOVA indicated no significant differences in anxiety levels among the patients based on gender. Both patients wore the VR device throughout the procedure, expressing that it was comfortable, diverting, and held the potential to alleviate anxiety and pain. The dentist noted a positive influence on patient anxiety levels and procedure completion times, expressing an intention to continue employing VR with other angioedema patients and across diverse clinical populations.</p><p><strong>Conclusions: </strong>Virtual reality can be an excellent distraction tool in patients with hereditary angioedema who present at least one acute attack per year.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}