{"title":"Complications following oral biopsy: a prospective study in a cohort of patients referred to a public oral health service.","authors":"Alessandra Viola, Alessandro Chiavieri, Mattia Pramstraller, Alessandro Rizzi, Roberto Farina","doi":"10.23736/S2724-6329.26.05290-3","DOIUrl":"10.23736/S2724-6329.26.05290-3","url":null,"abstract":"<p><strong>Background: </strong>Information on complications related to oral biopsy (OB; defined as unexpected events occurring during or after OB and adversely affecting its normal sequelae, as assessed/confirmed by a clinician) in public healthcare settings is currently limited. Within a cohort of patients referred for OB, we evaluated: 1) the nature and incidence of complications as well as their resolution; and 2) the association between patient-related and local factors and the incidence of complications.</p><p><strong>Methods: </strong>A prospective cohort study was performed on a convenience sample of patients referred for OB to a public oral health service. Intraoperative complications were recorded from anesthesia to the completion of the suturing phase. Postoperative complications were recorded between day +14 and +180 following OB and were followed at an additional visit at ≥180 days. Patient characteristics, surgery-related items, and descriptors of the lesion were comparatively evaluated in lesions experiencing or not experiencing complications.</p><p><strong>Results: </strong>One hundred and seven OBs contributed to the analysis. Twelve lesions (11.2%) experienced complications. Among these, 1 complication (0.9%) was intraoperative, while 11 (10.3%) were postoperative, including disease recurrence, paresthesia, and fibrous scar. The observed trends suggested that excisional OB, lower lip and mucocele may represent factors negatively influencing the rate and severity of complications.</p><p><strong>Conclusions: </strong>OB is generally a safe and well-tolerated procedure, even in vulnerable patient cohorts. However, a non-negligible proportion of lesions may still experience intra- or postoperative issues, consisting primarily of disease recurrence and paresthesia which, in isolated cases, may persist. OB surgery for mucocele excision in the lips should be performed with caution due to the high risk for recurrence and paresthesia.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"318-325"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148592708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pradeep Kumar Yadalam, Jeevitha Manickavasagam, Trisha Sasikumar, Maria Maddalena Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini
{"title":"AI-based prediction and classification of root caries using radiographic images.","authors":"Pradeep Kumar Yadalam, Jeevitha Manickavasagam, Trisha Sasikumar, Maria Maddalena Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04967-2","DOIUrl":"10.23736/S2724-6329.24.04967-2","url":null,"abstract":"<p><strong>Background: </strong>Root surface caries, commonly known as root decay, is a common dental disorder that affects tooth roots. Like enamel-based tooth decay, root caries attack exposed root surfaces caused by gum recession or periodontal disease. Older persons with gum recession, tooth loss, or poor oral hygiene may be more likely to develop this disorder. Dental root caries must be diagnosed early to improve treatment and prevention. This research will examine radiographic image-based AI-based root caries prediction algorithms.</p><p><strong>Methods: </strong>Saveetha Dental College supplied 200 root surface radiographs. An expert dentist and dental radiologist confirmed one hundred teeth with root caries and 100 without. Edited and segmented radiographic images. Orange, a machine learning squeeze net embedding model with Naive Bayes, Logistic Regression, and neural networks, was used to assess prediction accuracy. Training and test data were split 80/20. Cross-validation, confusion matrix, and ROC analysis assessed model performance. This study examined precision and recall.</p><p><strong>Results: </strong>Naïve bayes and logistic regression have 96% and 100% accuracy, but class accuracy is -94% and 100% in image classification of root caries was seen.</p><p><strong>Conclusions: </strong>AI-based root caries prediction utilizing radiographic images would improve dental care by diagnosing and treating early, accurately, and personalized. With appropriate deployment, research, and ethics, AI integration in dentistry could benefit practitioners and patients. Dental professionals and AI experts must work together to maximize this new technology.AI integration in dentistry can significantly improve root caries diagnosis and treatment by predicting root caries using radiographic images. This early detection reduces treatment need and time. Collaboration between dental professionals and AI experts is crucial for maximizing benefits.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"309-317"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuliano Ascani, Susanna DI Valerio, Erminia DI Nobile
{"title":"Clinical considerations in the management of natal and neonatal teeth: a brief report and commentary.","authors":"Giuliano Ascani, Susanna DI Valerio, Erminia DI Nobile","doi":"10.23736/S2724-6329.26.05241-1","DOIUrl":"10.23736/S2724-6329.26.05241-1","url":null,"abstract":"","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"349-350"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors and management of adverse events in tooth extraction among medically compromised patients.","authors":"Giath Gazal, Mohammad Z Nassani, Salah Sakka","doi":"10.23736/S2724-6329.26.05281-2","DOIUrl":"10.23736/S2724-6329.26.05281-2","url":null,"abstract":"<p><p>Tooth extraction in medically compromised adults presents significant clinical challenges due to an increased risk of bleeding, infection, delayed healing, and systemic complications. The review indicated that Diabetes mellitus affects 8-12% of dental patients and is associated with a 10-15% risk of intraoperative hypoglycemia, while anticoagulated patients experience postoperative bleeding in 8-12% of cases compared with 2-3% in controls. Hypertension affects up to 30% of adults, leading to perioperative blood pressure elevations in 20-25%, and asthma or chronic obstructive pulmonary disease COPD occurs in 7-10% of patients with a 3-6% risk of bronchospasm. Immunosuppressed and transplant patients show postoperative infection rates as high as 20%. Five structured tables summarize medical classifications, safe clinical thresholds, emergency management, referral criteria, and a stepwise safety ladder for pre-, intra-, and postoperative care. The review emphasizes the importance of strict risk stratification and adherence to validated clinical cut-offs, including HbA1c <9%, INR ≤3.5, and blood pressure <180/110 mmHg. Implementation of standardized safety ladders and evidence-based thresholds can enhance patient safety, improve decision-making, and promote global consistency in managing medically compromised dental patients.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"342-348"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148592641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Díaz-Flores García, Susana David Fernández, Giuseppe D'Albis, Saverio Capodiferro, Ana Suarez, Yolanda Freire
{"title":"Exploring ChatGPT's clinical role in prosthodontics: a systematic review.","authors":"Victor Díaz-Flores García, Susana David Fernández, Giuseppe D'Albis, Saverio Capodiferro, Ana Suarez, Yolanda Freire","doi":"10.23736/S2724-6329.26.05257-5","DOIUrl":"10.23736/S2724-6329.26.05257-5","url":null,"abstract":"<p><strong>Background: </strong>The integration of artificial intelligence (AI) into clinical dentistry has opened new avenues for diagnostic support and treatment planning. Among AI tools, large language models such as ChatGPT have shown potential in assisting clinical reasoning. Prosthodontics, due to its interdisciplinary complexity and individualized treatment protocols, presents a particularly demanding context for evaluating such technologies. This systematic review critically examines the clinical performance of ChatGPT in prosthodontics, focusing on diagnostic accuracy, treatment planning, and decision-making.</p><p><strong>Methods: </strong>A systematic search was conducted across PubMed, Scopus, Web of Science, and the Cochrane Library for studies published between January 2022 and August 2025. Inclusion criteria encompassed original research assessing ChatGPT's performance in prosthodontic contexts. Eight studies met the eligibility criteria, including observational, experimental, and case-based designs. Data extraction and synthesis adhered to ENTREQ and PRISMA guidelines to ensure methodological transparency and reproducibility.</p><p><strong>Results: </strong>ChatGPT-4 consistently outperformed earlier versions in terms of coherence, clinical relevance, and reasoning quality. Applications ranged from implant-supported prosthesis planning and occlusal analysis to prosthetic shade selection. Structured prompting techniques, particularly Chain-of-Thought, significantly enhanced response accuracy and consistency. Across the eight included studies, most reported moderate to high response reliability, although variability remained in complex clinical scenarios. Repeatability analyses revealed moderate to high intra-model reliability, although susceptibility to hallucinations and variability in complex scenarios remain limitations. Most studies were simulation-based, with limited validation in real clinical settings.</p><p><strong>Conclusions: </strong>ChatGPT exhibits promising capabilities as a supplementary tool in prosthodontics, particularly for educational purposes and preliminary clinical reasoning. However, its direct clinical application should be approached with caution and under professional oversight. Future research must prioritize empirical validation, standardized evaluation protocols, and regulatory frameworks to ensure safe and effective integration into prosthodontic practice.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"333-341"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does heat affect the performance of bioceramic sealers? A systematic review of warm obturation.","authors":"Fulvia Galletti, Cosimo Galletti, Gabriele Cervino, Luca Fiorillo, Cesare D'Amico","doi":"10.23736/S2724-6329.26.05181-8","DOIUrl":"10.23736/S2724-6329.26.05181-8","url":null,"abstract":"<p><strong>Background: </strong>The use of bioceramic sealers in endodontic treatment has gained traction due to their bioactivity, biocompatibility, and ability to promote mineralization. However, their integration with warm obturation techniques presents challenges, particularly concerning their thermal stability and adhesive properties. This review evaluates the compatibility of bioceramic sealers with warm obturation methods, focusing on the effects of heat on bond strength, physicochemical properties, and clinical outcomes.</p><p><strong>Methods: </strong>A systematic search of the literature identified 12 relevant studies, with results showing that controlled heat can enhance sealer flow and adaptation but excessive temperatures compromise bond strength and material stability.</p><p><strong>Results: </strong>Clinical studies demonstrate favorable outcomes for warm obturation techniques, provided that thermal thresholds are maintained. Advancements in bioceramic formulations may improve resilience to thermal challenges, highlighting the need for optimized obturation protocols and clear clinical guidelines.</p><p><strong>Conclusions: </strong>This review underscores the importance of balancing thermal enhancement with material preservation to achieve successful endodontic outcomes.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"326-332"},"PeriodicalIF":1.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Baldoni, Alessandra Gatti, Silvia Perazzolo, Luca Aglio, Cesare Ghitti
{"title":"Oral health management in pediatric patients with \"special needs\". Integrated hospital care model involving dentistry and pediatrics for the management of pediatric patients with hemato-oncologic diseases.","authors":"Marco Baldoni, Alessandra Gatti, Silvia Perazzolo, Luca Aglio, Cesare Ghitti","doi":"10.23736/S2724-6329.26.05218-6","DOIUrl":"https://doi.org/10.23736/S2724-6329.26.05218-6","url":null,"abstract":"<p><p>Dental care for pediatric patients with special needs represents a significant clinical and organizational challenge that requires an integrated, multidisciplinary, and personalized approach. This paper presents a structured model of collaboration between Dentistry and Pediatric Hematology-Oncology developed at the San Gerardo dei Tintori Hospital in Monza since 1999, aimed at providing comprehensive management for children affected by hematologic-oncologic diseases. The integration of these two disciplines led to the creation of a diagnostic-therapeutic-assistance pathway (hereinafter referred to as D.P.C., dentist-pediatrician-collaboration), which ensures timely and coordinated interventions for the prevention, diagnosis, and treatment of oral complications related to oncological therapies. Dental care is delivered across four main areas - diagnostic, preventive, therapeutic, and rehabilitative - contributing significantly to the improvement of quality of life throughout the treatment journey. The Monza experience offers a replicable model of personalized and integrated medicine, capable of anticipating needs, minimizing risks, and promoting the well-being of pediatric patients with special needs. No etichal approval was necessary for this study as it is just the description of the protocols of collaboration between dentists and pediatrician improved during the years.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148970215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Cinelli, Michele Nieri, Margherita Lucchesi, Martina Cavuoto, Veronica Giuntini, Lorenzo Franchi
{"title":"Diagnostic accuracy of a thermal microsensor for measuring wear time of removable extra-oral orthodontic appliances.","authors":"Francesca Cinelli, Michele Nieri, Margherita Lucchesi, Martina Cavuoto, Veronica Giuntini, Lorenzo Franchi","doi":"10.23736/S2724-6329.26.05319-2","DOIUrl":"https://doi.org/10.23736/S2724-6329.26.05319-2","url":null,"abstract":"<p><strong>Background: </strong>Adherence to orthodontic treatment with removable extra-oral appliances is a key factor influencing treatment outcomes. Objective compliance monitoring systems, such as the Theramon<sup>®</sup> microsensor, are increasingly used to assess wear time. The aim of this study was to evaluate the diagnostic accuracy of the Theramon<sup>®</sup> system in detecting wear time of removable extra-oral orthodontic appliances under controlled conditions and to identify the optimal temperature cut-off for maximizing detection accuracy in both winter and summer conditions.</p><p><strong>Methods: </strong>A diagnostic accuracy study was conducted on a convenience sample of five healthy volunteers at the Department of Experimental and Clinical Medicine, University of Florence. Two measurement sessions were performed, one in winter and one in summer. The Theramon<sup>®</sup> microsensor served as the index test. No independent reference standard was available; actual appliance wear time was determined using participant diaries, which were considered representative of true wear time. The optimal temperature cut-off was determined exploratorily during data analysis.</p><p><strong>Results: </strong>During the winter session, the optimal temperature cut-off was 29.12 °C, with a sensitivity of 0.990 (95% CI: 0.983-0.995) and specificity of 0.999 (95% CI: 0.998-0.999). In the summer session, the optimal cut-off was 32.25 °C, with a sensitivity of 0.980 (95% CI: 0.971-0.986) and specificity of 0.971 (95% CI: 0.969-0.974). When data from both sessions were combined, a cut-off of 31 °C was selected, resulting in a sensitivity of 0.984 (95% CI: 0.979-0.988) and specificity of 0.969 (95% CI: 0.967-0.971).</p><p><strong>Conclusions: </strong>Under controlled conditions, the Theramon<sup>®</sup> microsensor demonstrated high diagnostic accuracy in monitoring wear time of removable extra-oral orthodontic appliances. These findings support its clinical use for objectively assessing patient adherence to devices such as the facial mask.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison between screw-retained and conometric technique in full-arch implant prosthetic rehabilitation regarding operative time needed: an in-vitro study.","authors":"Pietro Jacotti, Chiara Cioffi, Fabio Savoldi, Luca Visconti, Nicola Scazzero, Domenico Dalessandri","doi":"10.23736/S2724-6329.26.05287-3","DOIUrl":"https://doi.org/10.23736/S2724-6329.26.05287-3","url":null,"abstract":"<p><strong>Background: </strong>A common issue with full-arch implant rehabilitations is the inconvenience of prosthesis removal, which must be performed every 6-12 months to ensure proper hygiene. The purpose of this study was to compare the most used technique for full arch prostheses, the screw-retained, with the conometric technique, less discussed in the literature, which could give advantages in terms of removal and reinsertion time.</p><p><strong>Methods: </strong>The main component used was the implant-prosthetic connection Orbit (Bionica), which allowed for testing both conometric and screw-retained techniques. The first phase of the study (activation phase) focused on testing the activation of the copings in a standardized manner using a prosthetic driver at different torque values, from 10 Ncm to 30 Ncm, and then pulled to observe the force was required for decoupling. The second phase (time phase) compared the techniques to determine whether there were differences based on operators' experience, and secondly, which technique was faster.</p><p><strong>Results: </strong>The activation phase resulted in a 15 Ncm value in which there was no deformation of the coping. The time phase showed that the screw-retained technique is quicker in delivery than the conometric technique (average of 6 min 4 s vs. 13 min 56 s for the all-on-four, average of 8 min 0 s vs. 18 min 37 s for the all-on-six), but on the other hand, the conometric technique is faster in check-ups (average of 9 min 2 s vs. 0 min 30 s for the all-on-four, average of 12 min 41 s vs. 0 min 43 s for the all-on-six).</p><p><strong>Conclusions: </strong>With the chosen components, it is possible to fabricate a prosthesis in a less operator-dependent manner. Because of the working times required, we hypothesize that the screw-retained technique should be preferred for provisional prosthetic restorations, while the conometric technique for permanent restorations.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Mergoni, Nicola Ragazzon, Benedetta Ghezzi, Andrea Salvaterra Toffoli, Jardel F Mazzi-Chaves, Maddalena Manfredi
{"title":"Italian research in Endodontics: a 30-year bibliometric analysis.","authors":"Giovanni Mergoni, Nicola Ragazzon, Benedetta Ghezzi, Andrea Salvaterra Toffoli, Jardel F Mazzi-Chaves, Maddalena Manfredi","doi":"10.23736/S2724-6329.26.05266-6","DOIUrl":"10.23736/S2724-6329.26.05266-6","url":null,"abstract":"","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"305-307"},"PeriodicalIF":1.4,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147513382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}