Minerva dental and oral science最新文献

{"title":"Critical analysis of anatomy and classification of retromolar canal: an observational CBCT study.","authors":"Dardo Menditti, Pierluigi Mariani, Michele G Di Mare, Vittorio Patanè, Salvatore Cappabianca, Vittorio S Menditti, Antonio De Luca, Marco Menditti, Alfonso Reginelli","doi":"10.23736/S2724-6329.24.05011-3","DOIUrl":"10.23736/S2724-6329.24.05011-3","url":null,"abstract":"<p><strong>Background: </strong>The retromolar canal (RMC) is an anatomical structure of the mandibular bone located distal to the last molar. The frequency of anatomical variation in human anatomy is approximately 30-35%. This study aimed to evaluate the prevalence of the retromolar canal in a population subjected to cone beam computed tomography (CBCT).</p><p><strong>Methods: </strong>The radiographic images belonged to 200 patients (100 males and 100 females; older than 13 years old) were examined following a strict protocol. Four hundred hemi-mandibles of 100 male and 100 female patients were examined between 2019 and 2022.</p><p><strong>Results: </strong>The collected data showed 136 patients presented the RMC, bilateral in 72 cases (68%) and unilateral in the other 64 cases (32%). Gender variation did not yield statistically significant differences, with 76 male (56%) and 60 female (44%) patients affected (P>0.05). A statistically significant difference was observed for side predilection, with unilateral RMC more prevalent on the right side in 24 cases (37.5%) and on the left side in 40 cases (62.5%) (P<0.05).</p><p><strong>Conclusions: </strong>Based on the results obtained and other anatomical considerations, this study proposes a new classification for RMC.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"35-41"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142350246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and radiographic retrospective examination of data from patients who received endosseous zygomatic dental implants to support maxillary full-arch prostheses.","authors":"Giovanni-Battista Menchini-Fabris, Paolo Toti, Tommaso Grandi, Cesare Paoleschi, Luisa Paoleschi, Ugo Covani, Michele Di Cosola","doi":"10.23736/S2724-6329.24.05058-7","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05058-7","url":null,"abstract":"<p><strong>Background: </strong>In recent decades, implant dentistry has evolved to become a highly predictable treatment modality in the rehabilitation of different types of edentulism. The present retrospective analysis aimed to report the middle-term outcome of severely atrophic jaws rehabilitated with extra-maxillary zygomatic implants placed in conjunction with standard implants.</p><p><strong>Methods: </strong>Thirty-one patients were included in the present study with 62 zygomatic implants and 90 standard implants positioned. Outcome measures were prosthetic success/survival, implant success/survival, complications, modified Plaque Index (mPLI), modified Bleeding Index (mBI), mucosal seal efficacy evaluation (MSEE) >4 mm, and zygomatic implants classification level (ZICL).</p><p><strong>Results: </strong>No implant and no prosthesis were lost; one patient had mucositis at one zygomatic implant; implant and prosthetic cumulative success rates at more than 3 years were respectively 98.4% and 87% using implant and patient as units of analysis. Mechanical and biological complications occurred in seven patients; all resolved. Eighty percent of the patients practiced proper hygiene and 77% of patients suffered absent or minor mucosal bleeding. Distribution of the variable \"mucosal seal efficacy evaluation\" led to 81% of sites with values less than 4, and 19% of sites with values higher than 4. In more than 80% of cases, so then, the zygomatic implants clinical level showed a level 1 at the end of the survey.</p><p><strong>Conclusions: </strong>With 100% survival rates, zygomatic bilateral prosthetic configurations were an effective therapeutic option for individuals with highly reabsorbed maxillae undergoing initial full-arch fixed rehabilitation.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":"74 1","pages":"1-11"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple method to identify implant sites in totally edentulous arches: a pilot study with thermo-printed templates used with cone beam computed tomography.","authors":"Enzo Cumbo, Giuseppe Gallina, Pietro Messina, Giuseppe A Scardina","doi":"10.23736/S2724-6329.24.04998-2","DOIUrl":"10.23736/S2724-6329.24.04998-2","url":null,"abstract":"<p><strong>Background: </strong>All dental implants must be placed following radiological, clinical and aesthetic indications in compliance with prosthetic principles avoiding iatrogenic damage to patients. In implantology, among the key choices, to obtain predictable results, it is essential to establish (by cone beam computed tomography [CBCT]) the sites where to insert the implants; these sites must be identified, during the surgical phase, in the oral cavity. Surgical guides represent a valid aid especially in complex cases that require multiple implants. For some clinical conditions, expert operators choose the free hand technique during which identifying the chosen implant sites on CBCT in the oral cavity is more difficult.</p><p><strong>Methods: </strong>This experimental study is based on the use of thermo-molded mask as an alternative to surgical guides when the freehand technique is adopted in totally edentulous patients. These innovative masks, containing radiopaque references, are initially worn by patients during the execution of the CBCT, and later during surgery to identify the implant sites in the oral cavity.</p><p><strong>Results: </strong>The procedure described proved to be very useful and able to increase the precision of the freehand technique even if it does not provide information on the inclination of the implants. The metal references help clinical identification of the implant site.</p><p><strong>Conclusions: </strong>Our thermo-molded masks, in particular clinical conditions, could represent a valid and economical alternative to the classic surgical guide. The described procedure does not increase costs for the patient and significantly increases the precision in inserting the implants during free-hand techniques.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":"26-34"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel index for the evaluation of wound healing following erupted tooth extraction.","authors":"Vincenzo Marchio, Chiara Cinquini, Mattia Priami, Marco Nisi, Francesco Gulia, Elisabetta Carli, Antonio Barone","doi":"10.23736/S2724-6329.24.05059-9","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05059-9","url":null,"abstract":"<p><strong>Background: </strong>Understanding healing of the alveolar process is crucial for immediate implant, alveolar ridge preservation and guided bone regeneration procedures, and to evaluate it several different scales have been proposed; however, all have different characteristics and seem to miss a standardization allowing for an objective and dichotomous evaluation of the different aspects of wound healing. The objective of the present study is to propose and apply, in real clinical scenarios, a novel index for the objective evaluation of wound healing following erupted tooth extraction.</p><p><strong>Methods: </strong>Healthy patients in need of a single tooth extraction were enrolled and re-examined at 7, 14 and 21 days after the extraction using the novel index proposed. For each follow up, a score ranging from 0 to 10 based on dichotomous factors (0-1) was obtained.</p><p><strong>Results: </strong>Ten patients were enrolled in the study, 7 females and 3 males; the scores obtained at 21 days were coherent with the clinical appearance of the wound, and an excellent wound healing was obtained for everyone, except for two patients.</p><p><strong>Conclusions: </strong>The proposed scale seems to accurately indicate the actual clinical status of the post-extraction wound and provide useful information on overall wound healing. Further validation of the scale is needed in future studies.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors that affect alginates: a brief review.","authors":"Cesare D'Amico, Francesca Gorassini, Fabiana Nicita, Fulvia Galletti, Vincenzo Ronsivalle, Marco Portelli, Luca Fiorillo","doi":"10.23736/S2724-6329.24.05022-8","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05022-8","url":null,"abstract":"<p><p>Alginates are widely used in dentistry for various applications due to their favorable properties, including ease of use, cost-effectiveness, and patient comfort. They are commonly employed for preliminary impressions of oral structures in dental practice. This study aims to assess the impact of different factors on the performance of alginate impression materials in dentistry. The mixing process of alginate involves combining the powder with water, and the technique employed for mixing can significantly affect the quality and porosity of the resulting material. The study employed a comprehensive search strategy using electronic databases and manual searches to gather relevant studies published in English. The results indicated that the amount of water used for mixing and the presence of calcium ions could affect the setting time, hardness, and elasticity of alginate impressions. Proper water-powder ratio and manipulation instructions are crucial in minimizing distortion in the resulting casts. Disinfectants like chlorhexidine can effectively reduce microorganism percentages on the impression surface without compromising quality. Various mixing techniques were evaluated, including manual spatulation, automated spinning bowl, centrifugal mixer, and vacuum mixer. Centrifugal and vacuum mixing showed better surface and internal porosity results-mechanical mixing techniques, such as vacuum mixers, improved performance.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pro-angiogenic VEGF inhibition by cadaverine and hydrocinnamic acid metabolites: impairment of periodontal regeneration due to periodontal inflammation.","authors":"Pradeep K Yadalam, Raghavendra V Anegundi, Ramya Ramadoss, Deepti Shrivastava, Kumar C Srivastava, Rocco Franco, Giuseppe Minervini, Cesare D'Amico","doi":"10.23736/S2724-6329.24.04929-5","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04929-5","url":null,"abstract":"<p><strong>Background: </strong>Cadaverine and hydrocinnamic acid are frequent metabolites in inflamed periodontal areas. Their role as a metabolite for plant growth inhibition has been established, but their relevance in humans has yet to be determined. Moreover, Vascular endothelial growth factor (VGEF) is a consistent growth factor in neo-angiogenesis in periodontal regeneration. The aim of the study was to utilize an in-silico approach to investigate the potential interaction between Cadaverine and hydrocinnamic acid, metabolites found in inflamed periodontal areas, and vascular endothelial growth factor (VEGF), with a focus on understanding their role in periodontal regeneration.</p><p><strong>Methods: </strong>Desmond MD simulation is an efficient technique for analyzing the dynamics of protein-ligand complexes. The system is minimized and equilibrated after the protein-ligand combination has been solvated in a water box. The system is simulated for a desired time, typically 10-100 nanoseconds. The simulation data is examined to reveal the interactions between proteins and ligands, such as binding affinities, contact maps, and hydrogen bonding patterns. VEGF interactome of metabolites was assessed.</p><p><strong>Results: </strong>Docking interactions between hydrocinnamic acid and VEGF with binding energy -5.0 kcal/mol and docking interactions between Cadaverine and VEGF with -3.6 kcal/mol. Fluctuations in RMSD values remain within 2.0 for the simulation duration, which is perfectly fine. Ligand RMSD values fluctuated within 1.0 Angstrom up to 25 ns, flipped in ligand mode, regained equilibrium at 80 ns, and remained steady for the simulation duration.</p><p><strong>Conclusions: </strong>The current in-silico study suggests that metabolites like Cadaverine and hydrocinnamic acid, which are produced during periodontal inflammation, may have the ability to block pro-angiogenic vascular endothelial growth factors. This interference can have notable effects on the healing and regeneration of tissues by preventing the formation of blood vessels and the expression of VEGF.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basal implants as a treatment alternative for severely resorbed ridges.","authors":"Fadia Awadalkreem, Kusai Baroudi, Giuseppe Minervini, Yazan Zaineh, Ebrahim Al-Mehdhar","doi":"10.23736/S2724-6329.24.05066-6","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.05066-6","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to evaluate the long-term treatment outcomes of basal implants in patients with severely resorbed ridges, including the survival and success rates, patient complaints, satisfaction, and Quality of Life.</p><p><strong>Evidence acquisition: </strong>An extensive electronic search was conducted on the search engines: PubMed, Web of Science, and Google Scholar using Boolean Operators (AND, OR, NOT) and the key words (basal implants, Corticobasal implants, Strategic Implants, severely resorbed ridge, severely atrophic ridge, treatment outcome, patient satisfaction) within the last 10 years.</p><p><strong>Evidence synthesis: </strong>A total of 21 articles were found, encompassing 9732 basal implants placed in 1219 patients. Thirteen studies had reported a success or survival rate with a range of 90.3-100% for intraoral basal implants and 88.2% and 92.9% for orbital and nasal implants, respectively. Four studies have reported failure rates with a range of 0.3-3.2%, while seven articles documented 0.3-2.4% mobility. The pain was reported in 6 studies (0.3-0.8), marginal bone loss (0.33-7.89 mm), an increase in bone density, and peri-implant bone contact were reported in 3 and 2 studies, respectively.</p><p><strong>Conclusions: </strong>Basal implant-supported prostheses can be a practical treatment modality with high predictable survival or success rates, positive impacts on patient satisfaction, and improved quality of life.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boswellic acid exerts anti-tumor effect in oral squamous cell carcinoma by inhibiting PI3K/AKT1 mediated signaling pathway.","authors":"Sathan Raj Natarajan, Vishnu Priya Veeraraghvan, Selvaraj Jayaraman, Maria Maddalena Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04918-0","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04918-0","url":null,"abstract":"<p><strong>Background: </strong>Boswellic acid (BA) is a bioactive compound derived from Boswellia trees. This study aims to investigate the anti-cancer properties of BA against KB oral squamous cancer cells and elucidate the underlying mechanisms.</p><p><strong>Methods: </strong>Escalating doses of BA were administered to KB cells, and various analyses were conducted using bioinformatic tools such as GEO, GEO2R, and STITCH database. MTT and trypan blue assays has been validated to measure the cytotoxicity by treating BA in KB Cells. Flow cytometry assessed cell cycle progression, apoptosis induction, and metabolic alterations. Network analysis identified relevant signaling pathways, while RT-PCR validated mRNA expression changes. Docking studies by Autodock evaluated beta-BA's binding affinity with mTOR-mediated pathways.</p><p><strong>Results: </strong>BA effectively hindered KB cell progression, inducing G0/G1 phase cell cycle arrest and apoptosis. It also inhibited aerobic glycolysis, a hallmark of oral cancer cells. Network analysis revealed involvement in apoptosis and mTOR targets. RT-PCR confirmed downregulation of genes associated with aerobic glycolysis and apoptosis. Docking studies indicated strong binding between BA and mTOR pathways.</p><p><strong>Conclusions: </strong>BA shows promise in inhibiting KB oral squamous cancer cell growth. These findings underscore its potential as a treatment for oral cancer. Further research and clinical studies are needed to unlock its full therapeutic potential.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conventional periodontal probing versus salivary biomarkers in diagnosis and evaluation of chronic periodontitis in type 2 diabetes mellitus.","authors":"Bukanakere S Sunila, Ganiga C Shivakumar, Nishath S Abdul, Neha Sudhakar, Rocco Franco, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.23736/S2724-6329.24.04867-8","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04867-8","url":null,"abstract":"<p><p>Chronic periodontitis is a prevalent inflammatory condition that affects both the oral health and systemic well-being of individuals, particularly those with type 2 diabetes mellitus (T2DM). Accurate diagnosis and evaluation of periodontal status are crucial for effective management of the disease. This narrative review aimed to compare the diagnostic and evaluative capabilities of conventional periodontal probing and salivary biomarkers in chronic periodontitis among individuals with T2DM. The available literature highlights the clinical utility of conventional periodontal probing as the gold standard for periodontal diagnosis and evaluation. It enables the assessment of clinical parameters such as probing depth, clinical attachment level, and bleeding on probing, providing valuable information about the severity and extent of periodontal disease. However, this approach has limitations, including its invasive nature, potential for examiner bias, and limited ability to detect early stages of periodontitis. In recent years, salivary biomarkers have emerged as promising diagnostic tools for periodontal diseases. Various biomarkers, such as inflammatory cytokines, matrix metalloproteinases, and host-derived enzymes, have shown potential in differentiating periodontal health from disease and assessing disease activity. Salivary biomarker analysis offers advantages such as non-invasiveness, ease of collection, and the potential for chair-side testing. However, standardization of collection protocols, biomarker panels, and interpretation criteria remain a challenge. This narrative review provides an overview of the strengths and limitations of conventional periodontal probing and salivary biomarkers in the diagnosis and evaluation of chronic periodontitis in individuals with T2DM. Both approaches have their unique advantages and contribute valuable information in clinical practice. Combining conventional periodontal probing with salivary biomarker analysis holds promise for enhancing the accuracy and precision of periodontal disease diagnosis and monitoring in individuals with T2DM.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking the potential: a historical perspective on the evolution of exfoliative cytology in oral cavity neoplasms.","authors":"Luca Fiorillo, Cesare D'Amico, Francesca Gorassini, Vini Mehta, Giuseppe Minervini, Gabriele Cervino","doi":"10.23736/S2724-6329.24.04857-5","DOIUrl":"https://doi.org/10.23736/S2724-6329.24.04857-5","url":null,"abstract":"<p><p>Exfoliative cytology has proven to be a valuable diagnostic tool in the early detection of malignant neoplasms. However, its application in the oral cavity has been met with skepticism and limited investigation due to the perception that clinical examination alone is sufficient for early diagnosis. Nonetheless, recent research efforts have focused on the utility of exfoliative cytology in oral cavity neoplasms, motivated by the high mortality rate associated with oral cancer. This manuscript reviews the historical development of exfoliative cytology in the oral cavity, highlighting key findings and advancements in the field. Early studies demonstrated the presence of neoplastic cells in oral cavity lesions and emphasized the diagnostic potential of cytology. Subsequent research explored different staining methods and observed the differential reaction of oral cavity cells to radiation therapy. The diagnostic accuracy of exfoliative cytology was reported to be as high as 92%, with a significant number of cases diagnosed as carcinomas without any clinical suspicion. The technique also proved valuable in identifying precancerous and dysplastic lesions and obviating the need for unnecessary biopsies. The manuscript delves into the difficulties encountered in sampling techniques and stresses the significance of appropriate specimen collection and handling. Various staining methods, including Papanicolaou and acridine orange, were utilized for cytological analysis. The manuscript emphasizes the extensive use of exfoliative cytology in oral cavity examinations and stresses the importance of recognizing it as a crucial diagnostic tool. Various studies have reported high positivity rates and the detection of clinically unsuspected malignant lesions. The authors recommend extensive use of exfoliative cytology in routine practice and underscore the necessity of proper sampling and evaluation techniques.</p>","PeriodicalId":18709,"journal":{"name":"Minerva dental and oral science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}