MMWR. Morbidity and mortality weekly report最新文献

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Reported Incidence of Infections Caused by Pathogens Transmitted Commonly Through Food: Impact of Increased Use of Culture-Independent Diagnostic Tests - Foodborne Diseases Active Surveillance Network, 1996-2023. 通过食物传播的常见病原体引起的感染报告发病率:更多使用独立于培养基的诊断检测的影响 - 食源性疾病主动监测网络,1996-2023 年。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-07-04 DOI: 10.15585/mmwr.mm7326a1
Hazel J Shah, Rachel H Jervis, Katie Wymore, Tamara Rissman, Bethany LaClair, Michelle M Boyle, Kirk Smith, Sarah Lathrop, Suzanne McGuire, Rosalie Trevejo, Marcy McMillian, Stic Harris, Joanna Zablotsky Kufel, Kennedy Houck, Carey E Lau, Carey J Devine, Dave Boxrud, Daniel L Weller
{"title":"Reported Incidence of Infections Caused by Pathogens Transmitted Commonly Through Food: Impact of Increased Use of Culture-Independent Diagnostic Tests - Foodborne Diseases Active Surveillance Network, 1996-2023.","authors":"Hazel J Shah, Rachel H Jervis, Katie Wymore, Tamara Rissman, Bethany LaClair, Michelle M Boyle, Kirk Smith, Sarah Lathrop, Suzanne McGuire, Rosalie Trevejo, Marcy McMillian, Stic Harris, Joanna Zablotsky Kufel, Kennedy Houck, Carey E Lau, Carey J Devine, Dave Boxrud, Daniel L Weller","doi":"10.15585/mmwr.mm7326a1","DOIUrl":"10.15585/mmwr.mm7326a1","url":null,"abstract":"<p><p>Reducing foodborne disease incidence is a public health priority. This report summarizes preliminary 2023 Foodborne Diseases Active Surveillance Network (FoodNet) data and highlights efforts to increase the representativeness of FoodNet. During 2023, incidences of domestically acquired campylobacteriosis, Shiga toxin-producing Escherichia coli infection, yersiniosis, vibriosis, and cyclosporiasis increased, whereas those of listeriosis, salmonellosis, and shigellosis remained stable compared with incidences during 2016-2018, the baseline used for tracking progress towards federal disease reduction goals. During 2023, the incidence and percentage of infections diagnosed by culture-independent diagnostic tests (CIDTs) reported to FoodNet continued to increase, and the percentage of cases that yielded an isolate decreased, affecting observed trends in incidence. Because CIDTs allow for diagnosis of infections that previously would have gone undetected, lack of progress toward disease reduction goals might reflect changing diagnostic practices rather than an actual increase in incidence. Continued surveillance is needed to monitor the impact of changing diagnostic practices on disease trends, and targeted prevention efforts are needed to meet disease reduction goals. During 2023, FoodNet expanded its catchment area for the first time since 2004. This expansion improved the representativeness of the FoodNet catchment area, the ability of FoodNet to monitor trends in disease incidence, and the generalizability of FoodNet data.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 26","pages":"584-593"},"PeriodicalIF":25.4,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment - United States, July 2022-September 2023. 2022 年 7 月至 2023 年 9 月接受药物使用治疗评估的年龄≥18 岁成人中报告的 Xylazine 使用情况 - 美国。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-07-04 DOI: 10.15585/mmwr.mm7326a2
Xinyi Jiang, Sarah Connolly, Andrea E Strahan, Liz Rivera Blanco, Christina A Mikosz, Gery P Guy, Deborah Dowell
{"title":"Reported Xylazine Use Among Adults Aged ≥18 Years Evaluated for Substance Use Treatment - United States, July 2022-September 2023.","authors":"Xinyi Jiang, Sarah Connolly, Andrea E Strahan, Liz Rivera Blanco, Christina A Mikosz, Gery P Guy, Deborah Dowell","doi":"10.15585/mmwr.mm7326a2","DOIUrl":"10.15585/mmwr.mm7326a2","url":null,"abstract":"<p><p>Xylazine has been increasingly detected in illegally manufactured fentanyl (IMF) products and overdose deaths in the United States; most xylazine-involved overdose deaths involve IMF. A convenience sample of U.S. adults aged ≥18 years was identified from those evaluated for substance use treatment during July 2022-September 2023. Data were collected using the Addiction Severity Index-Multimedia Version clinical assessment tool. Among 43,947 adults, 6,415 (14.6%) reported IMF or heroin as their primary lifetime substance-use problem; 5,344 (12.2%) reported recent (i.e., past-30-day) IMF or heroin use. Among adults reporting IMF or heroin as their primary lifetime substance-use problem, 817 (12.7%) reported ever using xylazine. Among adults reporting recent IMF or heroin use, 443 (8.3%) reported recent xylazine use. Among adults reporting IMF or heroin use recently or as their primary lifetime substance-use problem, those reporting xylazine use reported a median of two past nonfatal overdoses from any drug compared with a median of one overdose among those who did not report xylazine use; as well, higher percentages of persons who reported xylazine use reported other recent substance use and polysubstance use. Provision of nonjudgmental care and services, including naloxone, wound care, and linkage to and retention of persons in effective substance use treatment, might reduce harms including overdose among persons reporting xylazine use.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 26","pages":"594-599"},"PeriodicalIF":25.4,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Notes from the Field: Multidisciplinary Approach to Investigating Brucella canis Exposures - South Carolina, September 2023. 现场笔记:调查犬布鲁氏菌暴露的多学科方法 - 南卡罗来纳州,2023 年 9 月。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-27 DOI: 10.15585/mmwr.mm7325a3
Tori S Moore, Ashlyn Lancaster, Julia Nelson, Jennifer Sanders, Marnie Johnson, Amanda Moore, Marco Tori
{"title":"Notes from the Field: Multidisciplinary Approach to Investigating Brucella canis Exposures - South Carolina, September 2023.","authors":"Tori S Moore, Ashlyn Lancaster, Julia Nelson, Jennifer Sanders, Marnie Johnson, Amanda Moore, Marco Tori","doi":"10.15585/mmwr.mm7325a3","DOIUrl":"10.15585/mmwr.mm7325a3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 25","pages":"581-582"},"PeriodicalIF":25.4,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11254343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Persistent Transmission of Circulating Vaccine-Derived Poliovirus - Somalia, January 2017-March 2024. 源于疫苗的脊髓灰质炎病毒的持续传播 - 索马里,2017 年 1 月至 2024 年 3 月。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-27 DOI: 10.15585/mmwr.mm7325a2
Amalia Mendes, Gedi Abdi Mohamed, Mohamed Derow, Tasha Stehling-Ariza, Abdinoor Mohamed, Kumlachew Mengistu, Kelley Bullard, Irfan Elahi Akbar, Hemant Shukla, Mohammad Al Safadi, Maureen Martinez
{"title":"Persistent Transmission of Circulating Vaccine-Derived Poliovirus - Somalia, January 2017-March 2024.","authors":"Amalia Mendes, Gedi Abdi Mohamed, Mohamed Derow, Tasha Stehling-Ariza, Abdinoor Mohamed, Kumlachew Mengistu, Kelley Bullard, Irfan Elahi Akbar, Hemant Shukla, Mohammad Al Safadi, Maureen Martinez","doi":"10.15585/mmwr.mm7325a2","DOIUrl":"10.15585/mmwr.mm7325a2","url":null,"abstract":"<p><p>Since the launch of the Global Polio Eradication Initiative in 1988, substantial progress has been made in the interruption of wild poliovirus (WPV) transmission worldwide: global eradication of WPV types 2 and 3 were certified in 2015 and 2019, respectively, and endemic transmission of WPV type 1 continues only in Afghanistan and Pakistan. After the synchronized global withdrawal of all serotype 2 oral poliovirus vaccines (OPVs) in 2016, widespread outbreaks of circulating vaccine-derived poliovirus type 2 (cVDPV2) have occurred, which are linked to areas with low population immunity to poliovirus. Officials in Somalia have detected ongoing cVDPV2 transmission since 2017. Polio vaccination coverage and surveillance data for Somalia were reviewed to assess this persistent transmission. During January 2017-March 2024, officials in Somalia detected 39 cVDPV2 cases in 14 of 20 regions, and transmission has spread to neighboring Ethiopia and Kenya. Since January 2021, 28 supplementary immunization activities (SIAs) targeting cVDPV2 were conducted in Somalia. Some parts of the country are security-compromised and inaccessible for vaccination campaigns. Among 1,921 children with nonpolio acute flaccid paralysis, 231 (12%) had not received OPV doses through routine immunization or SIAs, 95% of whom were from the South-Central region, and 60% of whom lived in inaccessible districts. Enhancing humanitarian negotiation measures in Somalia to enable vaccination of children in security-compromised areas and strengthening campaign quality in accessible areas will help interrupt cVDPV2 transmission.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 25","pages":"575-580"},"PeriodicalIF":25.4,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11254344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment for Opioid Use Disorder: Population Estimates - United States, 2022. 阿片类药物使用障碍的治疗:人口估计 - 美国,2022 年。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-27 DOI: 10.15585/mmwr.mm7325a1
Deborah Dowell, Samantha Brown, Shiromani Gyawali, Jennifer Hoenig, Jean Ko, Christina Mikosz, Emily Ussery, Grant Baldwin, Christopher M Jones, Yngvild Olsen, Naomi Tomoyasu, Beth Han, Wilson M Compton, Nora D Volkow
{"title":"Treatment for Opioid Use Disorder: Population Estimates - United States, 2022.","authors":"Deborah Dowell, Samantha Brown, Shiromani Gyawali, Jennifer Hoenig, Jean Ko, Christina Mikosz, Emily Ussery, Grant Baldwin, Christopher M Jones, Yngvild Olsen, Naomi Tomoyasu, Beth Han, Wilson M Compton, Nora D Volkow","doi":"10.15585/mmwr.mm7325a1","DOIUrl":"10.15585/mmwr.mm7325a1","url":null,"abstract":"<p><p>In 2022, 81,806 opioid-involved overdose deaths were reported in the United States, more than in any previous year. Medications for opioid use disorder (OUD), particularly buprenorphine and methadone, substantially reduce overdose-related and overall mortality. However, only a small proportion of persons with OUD receive these medications. Data from the 2022 National Survey on Drug Use and Health were applied to a cascade of care framework to estimate and characterize U.S. adult populations who need OUD treatment, receive any OUD treatment, and receive medications for OUD. In 2022, 3.7% of U.S. adults aged ≥18 years needed OUD treatment. Among these, only 25.1% received medications for OUD. Most adults who needed OUD treatment either did not perceive that they needed it (42.7%) or received OUD treatment without medications for OUD (30.0%). Compared with non-Hispanic Black or African American and Hispanic or Latino adults, higher percentages of non-Hispanic White adults received any OUD treatment. Higher percentages of men and adults aged 35-49 years received medications for OUD than did women and younger or older adults. Expanded communication about the effectiveness of medications for OUD is needed. Increased efforts to engage persons with OUD in treatment that includes medications are essential. Clinicians and other treatment providers should offer or arrange evidence-based treatment, including medications, for patients with OUD. Pharmacists and payors can work to make these medications available without delays.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 25","pages":"567-574"},"PeriodicalIF":25.4,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11254342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
QuickStats: Percentage* of Current Cigarette Smokers Aged ≥18 Years Who Received Advice from a Health Professional To Quit Smoking,§ by Sex and Age Group - United States, 2022. QuickStats:按性别和年龄组分列的当前吸烟者† 年龄≥18 岁时接受过健康专家戒烟建议的百分比*§ - 美国,2022 年。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-20 DOI: 10.15585/mmwr.mm7324a5
{"title":"QuickStats: Percentage* of Current Cigarette Smokers<sup>†</sup> Aged ≥18 Years Who Received Advice from a Health Professional To Quit Smoking,<sup>§</sup> by Sex and Age Group - United States, 2022.","authors":"","doi":"10.15585/mmwr.mm7324a5","DOIUrl":"10.15585/mmwr.mm7324a5","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 24","pages":"565"},"PeriodicalIF":25.4,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Findings from the First Year of a Federally Funded, Direct-to-Consumer HIV Self-Test Distribution Program - United States, March 2023-March 2024. 由联邦政府资助、直接面向消费者的艾滋病毒自我检测分发计划第一年的调查结果 - 美国,2023 年 3 月至 2024 年 3 月。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-20 DOI: 10.15585/mmwr.mm7324a4
Travis Sanchez, Robin J MacGowan, Jennifer Hecht, Jessica M Keralis, Lucinda Ackah-Toffey, Avery Bourbeau, Ruth Dana, Emily A Lilo, Revae S Downey, Hannah Getachew-Smith, Marissa Hannah, Rachel Valencia, Eli Krebs, Emily S Pingel, Jennie Johnston Gayden, Jenna Norelli, Zavier Mason, Jennifer Mahn, Natalie Cramer, Robert Bole, Patrick Sullivan, Anuli N Nwaohiri, Jo Ellen Stryker, Athena P Kourtis, Elizabeth A DiNenno, Robyn Neblett Fanfair, Jonathan H Mermin, Kevin P Delaney
{"title":"Findings from the First Year of a Federally Funded, Direct-to-Consumer HIV Self-Test Distribution Program - United States, March 2023-March 2024.","authors":"Travis Sanchez, Robin J MacGowan, Jennifer Hecht, Jessica M Keralis, Lucinda Ackah-Toffey, Avery Bourbeau, Ruth Dana, Emily A Lilo, Revae S Downey, Hannah Getachew-Smith, Marissa Hannah, Rachel Valencia, Eli Krebs, Emily S Pingel, Jennie Johnston Gayden, Jenna Norelli, Zavier Mason, Jennifer Mahn, Natalie Cramer, Robert Bole, Patrick Sullivan, Anuli N Nwaohiri, Jo Ellen Stryker, Athena P Kourtis, Elizabeth A DiNenno, Robyn Neblett Fanfair, Jonathan H Mermin, Kevin P Delaney","doi":"10.15585/mmwr.mm7324a4","DOIUrl":"10.15585/mmwr.mm7324a4","url":null,"abstract":"<p><p>In September 2022, CDC funded a nationwide program, Together TakeMeHome (TTMH), to expand distribution of HIV self-tests (HIVSTs) directly to consumers by mail through an online ordering portal. To publicize the availability of HIVSTs to priority audiences, particularly those disproportionately affected by HIV, CDC promoted this program through established partnerships and tailored resources from its Let's Stop HIV Together social marketing campaign. The online portal launched March 14, 2023, and through March 13, 2024, distributed 443,813 tests to 219,360 persons. Among 169,623 persons who answered at least one question on a postorder questionnaire, 67.9% of respondents were from priority audiences, 24.1% had never previously received testing for HIV, and 24.8% had not received testing in the past year. Among the subset of participants who initiated a follow-up survey, 88.3% used an HIVST themselves, 27.1% gave away an HIVST, 11.7% accessed additional preventive services, and 1.9% reported a new positive HIVST result. Mailed HIVST distribution can quickly reach large numbers of persons who have never received testing for HIV or have not received testing as often as is recommended. TTMH can help to achieve the goal of diagnosing HIV as early as possible and provides a path to other HIV prevention and care services. Clinicians, community organizations, and public health officials should be aware of HIVST programs, initiate discussions about HIV testing conducted outside their clinics or offices, and initiate follow-up services for persons who report a positive or negative HIVST result.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 24","pages":"558-564"},"PeriodicalIF":25.4,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loneliness, Lack of Social and Emotional Support, and Mental Health Issues - United States, 2022. 孤独、缺乏社会和情感支持以及心理健康问题 - 美国,2022 年。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-20 DOI: 10.15585/mmwr.mm7324a1
Katherine V Bruss, Puja Seth, Guixiang Zhao
{"title":"Loneliness, Lack of Social and Emotional Support, and Mental Health Issues - United States, 2022.","authors":"Katherine V Bruss, Puja Seth, Guixiang Zhao","doi":"10.15585/mmwr.mm7324a1","DOIUrl":"10.15585/mmwr.mm7324a1","url":null,"abstract":"<p><p>Loneliness and lack of social connection are widespread and negatively affect physical and mental health and well-being. Data are limited for persons disproportionately affected by social disconnection, especially those who do not identify as heterosexual and cisgender. Using data from the 2022 Behavioral Risk Factor Surveillance System in 26 U.S. states, CDC examined associations of loneliness and lack of social and emotional support to mental health variables. Prevalence estimates for the mental health variables were significantly higher among adults who reported loneliness and lack of social and emotional support than among those adults who did not. The prevalence of loneliness was highest among respondents who identified as bisexual (56.7%) and transgender (range = 56.4%-63.9%). Prevalence of lack of social and emotional support was highest among those who identified as transgender female (44.8%), transgender gender nonconforming (41.4%), and those with household income below $25,000 (39.8%). Prevalences of stress, frequent mental distress, and history of depression were highest among bisexual (34.3%-54.4%) and transgender adults (36.1%-67.2%). Addressing the threat to mental health among sexual and gender minority groups should include consideration of loneliness and lack of social and emotional support. Providing access to health services that are affirming for sexual and gender minority groups and collecting data to address health inequities might help improve the delivery of culturally competent care.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 24","pages":"539-545"},"PeriodicalIF":25.4,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Distribution of Tecovirimat During the Peak of the Mpox Outbreak - Los Angeles County, June 2022-January 2023. 2022 年 6 月至 2023 年 1 月莫泊桑疫情高峰期间 Tecovirimat 的成功分发 - 洛杉矶县。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-20 DOI: 10.15585/mmwr,mm7324a2
Margaret J O'Neil, Roxanne Archer, Phoebe Danza, Rebecca Fisher, Dee Ann Bagwell, Ibrahim Younis, Sonali Kulkarni, Zachary Rubin, Moon Kim, Sharon Balter, Dawn Terashita, Jee Kim, Rita Singhal, Daniel Hancz, Marianne Gausche-Hill, Naman K Shah
{"title":"Successful Distribution of Tecovirimat During the Peak of the Mpox Outbreak - Los Angeles County, June 2022-January 2023.","authors":"Margaret J O'Neil, Roxanne Archer, Phoebe Danza, Rebecca Fisher, Dee Ann Bagwell, Ibrahim Younis, Sonali Kulkarni, Zachary Rubin, Moon Kim, Sharon Balter, Dawn Terashita, Jee Kim, Rita Singhal, Daniel Hancz, Marianne Gausche-Hill, Naman K Shah","doi":"10.15585/mmwr,mm7324a2","DOIUrl":"10.15585/mmwr,mm7324a2","url":null,"abstract":"<p><p>Tecovirimat is the first-line antiviral treatment recommended for severe mpox or for persons with mpox who are at risk for severe disease; tecovirimat is available in the United States under an expanded access investigational new drug (IND) protocol. During the 2022-2023 mpox outbreak, local U.S. health jurisdictions facilitated access to tecovirimat. In June 2022, Los Angeles County (LAC) rapidly developed strategies for tecovirimat distribution using existing medical countermeasure distribution networks established by the Public Health Emergency Preparedness Program and the Hospital Preparedness Program, creating a hub and spoke distribution network consisting of 44 hub facilities serving 456 satellite sites across LAC. IND patient intake forms were analyzed to describe mpox patients treated with tecovirimat. Tecovirimat treatment data were matched with case surveillance data to calculate time from specimen collection to patients receiving tecovirimat. Among 2,281 patients with mpox in LAC, 735 (32%) received tecovirimat during June 2022-January 2023. Among treated patients, approximately two thirds (508; 69%) received treatment through community clinics and pharmacies. The median interval from specimen collection to treatment was 2 days (IQR = 0-5 days). Local data collection and analysis helped to minimize gaps in treatment access and facilitated network performance monitoring. During public health emergencies, medical countermeasures can be rapidly deployed across a large jurisdiction using existing distribution networks, including clinics and pharmacies.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 24","pages":"546-550"},"PeriodicalIF":25.4,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency Medical Services Encounters for Firearm Injuries - 858 Counties, United States, January 2019-September 2023. 2019 年 1 月至 2023 年 9 月美国 858 个县火器伤害紧急医疗服务就诊情况。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2024-06-20 DOI: 10.15585/mmwr.mm7324a3
Adam Rowh, Marissa Zwald, Katherine Fowler, Shane Jack, Carlos Siordia, Josh Walters
{"title":"Emergency Medical Services Encounters for Firearm Injuries - 858 Counties, United States, January 2019-September 2023.","authors":"Adam Rowh, Marissa Zwald, Katherine Fowler, Shane Jack, Carlos Siordia, Josh Walters","doi":"10.15585/mmwr.mm7324a3","DOIUrl":"10.15585/mmwr.mm7324a3","url":null,"abstract":"<p><p>Firearm-related deaths and injuries have increased in recent years. Comprehensive and timely information on firearm injuries and the communities and geographic locations most affected by firearm violence is crucial for guiding prevention activities. However, traditional surveillance systems for firearm injury, which are mostly based on hospital encounters and mortality-related data, often lack information on the location where the shooting occurred. This study examined annual and monthly rates of emergency medical services (EMS) encounters for firearm injury per 100,000 total EMS encounters during January 2019-September 2023 in 858 counties in 27 states, by patient characteristics and characteristics of the counties where the injuries occurred. Overall, annual rates of firearm injury EMS encounters per 100,000 total EMS encounters ranged from 222.7 in 2019 to 294.9 in 2020; rates remained above prepandemic levels through 2023. Rates were consistently higher among males than females. Rates stratified by race and ethnicity were highest among non-Hispanic Black or African American persons; rates stratified by age group were highest among persons aged 15-24 years. The greatest percentage increases in annual rates occurred in urban counties and in counties with higher prevalence of severe housing problems, higher income inequality ratios, and higher rates of unemployment. States and communities can use the timely and location-specific data in EMS records to develop and implement comprehensive firearm injury prevention strategies to address the economic, social, and physical conditions that contribute to the risk for violence, including improvements to physical environments, secure firearm storage, and strengthened social and economic supports.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"73 24","pages":"551-557"},"PeriodicalIF":25.4,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11199023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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