MMWR. Morbidity and mortality weekly report最新文献

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Epidemiology of Symptomatic Human Metapneumovirus Infection in the CASCADIA Community-Based Cohort - Oregon and Washington, 2022-2024.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-04-03 DOI: 10.15585/mmwr.mm7411a2
Mila Shakya, Helen Y Chu, Janet A Englund, Melissa Briggs-Hagen, Marco Carone, Jennifer L Kuntz, Tina Lockwood, Claire M Midgley, Mark A Schmidt, Lea Starita, Ana A Weil, Ryan E Wiegand, Allison L Naleway, Ian D Plumb
{"title":"Epidemiology of Symptomatic Human Metapneumovirus Infection in the CASCADIA Community-Based Cohort - Oregon and Washington, 2022-2024.","authors":"Mila Shakya, Helen Y Chu, Janet A Englund, Melissa Briggs-Hagen, Marco Carone, Jennifer L Kuntz, Tina Lockwood, Claire M Midgley, Mark A Schmidt, Lea Starita, Ana A Weil, Ryan E Wiegand, Allison L Naleway, Ian D Plumb","doi":"10.15585/mmwr.mm7411a2","DOIUrl":"10.15585/mmwr.mm7411a2","url":null,"abstract":"<p><p>Human metapneumovirus (hMPV) is an important cause of respiratory illness. However, information about hMPV incidence, patient characteristics, and symptoms outside hospital settings is limited. During June 2022-March 2024, participants aged 6 months-49 years who were enrolled in the CASCADIA community-based cohort study submitted weekly illness surveys and nasal swabs, and completed follow-up illness surveys. Swabs collected 0-3 days before reporting new or worsening symptoms were tested for hMPV and other respiratory viruses by multiplex polymerase chain reaction. Incidence was analyzed using an exponential survival model. Among 3,549 participants, 306 had symptomatic hMPV infection, representing an average of 7.5 cases per 100 persons per year (95% CI = 6.7-8.4). Incidence was highest during January-March (adjusted hazard ratio [aHR] = 4.3; 95% CI = 3.0-6.0) compared with October-December, and among those aged 2-4 years (aHR = 5.8; 95% CI = 3.8-9.0) compared with those aged ≥40 years. The most frequently reported symptoms were cough (80.4%) and nasal congestion (71.9%). Among 252 (82.4%) participants who completed a post-illness follow-up survey, 68 (27.0%) missed work, school, or child care facility attendance. Together, these findings indicate that hMPV is a common cause of respiratory illness during late winter to spring, particularly among young children, and frequently disrupts daily activities. Understanding hMPV epidemiology can guide surveillance definitions, clinical testing, and prioritization of prevention strategies.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 11","pages":"188-193"},"PeriodicalIF":25.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus - United States, 2014-2024.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-04-03 DOI: 10.15585/mmwr.mm7411a1
Ndey Bassin Jobe, Erica Rose, Amber K Winn, Leah Goldstein, Zachary D Schneider, Benjamin J Silk
{"title":"Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus - United States, 2014-2024.","authors":"Ndey Bassin Jobe, Erica Rose, Amber K Winn, Leah Goldstein, Zachary D Schneider, Benjamin J Silk","doi":"10.15585/mmwr.mm7411a1","DOIUrl":"10.15585/mmwr.mm7411a1","url":null,"abstract":"<p><p>Human metapneumovirus (hMPV) infections cause acute respiratory illness and lower respiratory tract disease. Respiratory syncytial virus (RSV) is a closely related virus within the Pneumoviridae family, and hMPV and RSV infections are associated with similar clinical manifestations. Although no specific antiviral therapies or vaccines exist for hMPV, vaccines and monoclonal antibody products are available to protect against severe RSV disease. This report summarizes hMPV circulation relative to the timing of RSV epidemics before, during, and after the COVID-19 pandemic. Polymerase chain reaction testing results reported to the National Respiratory and Enteric Virus Surveillance System during July 2014-June 2024, were analyzed. Before the COVID-19 pandemic, the median hMPV season onset, peak, and offset occurred in early January, late March, and early June, respectively (median duration = 21 weeks). The 2021-22 season was atypically long (35 weeks); seasonality reverted to more typical patterns during the 2022-23 and 2023-24 seasons. In the two COVID-19 pandemic seasons (2021-22 and 2022-23) and one postpandemic season (2023-24), RSV offsets occurred earlier in January (2021-22 and 2022-23) or March (2023-24) than before the pandemic, when the median offsets occurred in April. The annual interval from peak RSV to peak hMPV circulation increased from a prepandemic median of 11.5 weeks (range = 2-17 weeks) to 19 weeks (range = 19-20 weeks) during and after the pandemic. Fewer than 5 weeks of cocirculation of RSV and hMPV occurred in most regions during the 2022-23 and 2023-24 seasons. Real-time surveillance of RSV and hMPV co-circulation patterns can help guide clinician-directed testing and supportive care, optimize the use of prevention products, prompt detection of and response to outbreaks, and help ensure health care system preparedness for seasonal increases in illnesses.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 11","pages":"182-187"},"PeriodicalIF":25.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Notes from the Field: Response to a Case of Travel-Associated Lassa Fever - Iowa, October-November 2024. 现场笔记:应对一例旅行相关拉沙热--爱荷华州,2024 年 10 月至 11 月。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-04-03 DOI: 10.15585/mmwr.mm7411a3
Diana L Von Stein, Alexandra Barger, Andrew Hennenfent, Robert Ramaekers, Amanda Mandi, Kenzie Teno, Karen Brust, Jonathan Simmons, Nicholas Mohr, Lisa Veach, Sudhir Kumar, Aneesa Afroze, Emily McCutchen, Amanda Bartling, Michael Pentella, Megan Nelson, Jennifer Craft, Rikki Hetzler, Amy Thoreson, Alicia Coppedge, Sam Jarvis, Jennifer Miller, Alison M Todres, Jessica L Wickline, Sheena Tarrant, Leanna Sayyad, Inna Krapiunaya, Amy Schuh, Amy Whitesell, Gerard C Kuotu, Kiara McNamara, Nancy Cornish, Shelly Schwedhelm, Angela Vasa, Angela Hewlett, Shantyl Galloway, Aaron D Kofman, Katrin S Sadigh, Robert Kruse, Barbara Knust, Matthew Donahue
{"title":"Notes from the Field: Response to a Case of Travel-Associated Lassa Fever - Iowa, October-November 2024.","authors":"Diana L Von Stein, Alexandra Barger, Andrew Hennenfent, Robert Ramaekers, Amanda Mandi, Kenzie Teno, Karen Brust, Jonathan Simmons, Nicholas Mohr, Lisa Veach, Sudhir Kumar, Aneesa Afroze, Emily McCutchen, Amanda Bartling, Michael Pentella, Megan Nelson, Jennifer Craft, Rikki Hetzler, Amy Thoreson, Alicia Coppedge, Sam Jarvis, Jennifer Miller, Alison M Todres, Jessica L Wickline, Sheena Tarrant, Leanna Sayyad, Inna Krapiunaya, Amy Schuh, Amy Whitesell, Gerard C Kuotu, Kiara McNamara, Nancy Cornish, Shelly Schwedhelm, Angela Vasa, Angela Hewlett, Shantyl Galloway, Aaron D Kofman, Katrin S Sadigh, Robert Kruse, Barbara Knust, Matthew Donahue","doi":"10.15585/mmwr.mm7411a3","DOIUrl":"10.15585/mmwr.mm7411a3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 11","pages":"194-196"},"PeriodicalIF":25.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newly Reported Chronic Hepatitis C Among Adults - Alaska, 2016-2023.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-27 DOI: 10.15585/mmwr.mm7410a1
Heather M Scobie, Jamie Allison, Nicholas Masters, Morrow Toomey, Ian Blake, Janet M Johnston, Eyasu Teshale, Robert Lawrence, Elizabeth Ohlsen, Dana Bruden, Marc Fischer, Joe McLaughlin
{"title":"Newly Reported Chronic Hepatitis C Among Adults - Alaska, 2016-2023.","authors":"Heather M Scobie, Jamie Allison, Nicholas Masters, Morrow Toomey, Ian Blake, Janet M Johnston, Eyasu Teshale, Robert Lawrence, Elizabeth Ohlsen, Dana Bruden, Marc Fischer, Joe McLaughlin","doi":"10.15585/mmwr.mm7410a1","DOIUrl":"10.15585/mmwr.mm7410a1","url":null,"abstract":"<p><p>Hepatitis C virus is a leading cause of chronic liver disease, hepatocellular carcinoma, and liver-related death and is targeted for global elimination as a public health threat by 2030. Universal screening is recommended for all adults aged ≥18 years and pregnant women during each pregnancy; periodic risk-based screening also is recommended. Persons with current infection should be linked to antiviral treatment, which usually results in a virologic cure within 8-12 weeks. To assess progress toward elimination, epidemiologic trends in newly reported chronic hepatitis C cases were assessed among adult Alaska residents during 2016-2023. Overall, 5,352 confirmed chronic hepatitis C cases were newly reported among adults aged ≥18 years. The average annual rate (cases per 100,000 population) was 121 and decreased a relative 30% from 142 during 2016-2019 to 99 during 2020-2023. Statistically significant decreases occurred for most groups. Groups with higher average rates included males, adults aged 18-39 years, residents of rural areas, and American Indian or Alaska Native persons. Hepatitis C surveillance can help monitor trends in health outcomes and identify groups needing tailored testing and treatment interventions toward hepatitis C elimination.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 10","pages":"161-166"},"PeriodicalIF":25.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Notes from the Field: Fatal Acanthamoeba Encephalitis in a Patient Who Regularly Used Tap Water in an Electronic Nasal Irrigation Device and a Continuous Positive Airway Pressure Machine at Home - New Mexico, 2023.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-27 DOI: 10.15585/mmwr.mm7410a4
Julia C Haston, Ibne K Ali, Shantanu Roy, Alexis Roundtree, Jessica Hofstetter, Savannah Pierson, Emily Helmrich, Paul Torres, Kodi Lockey, Roosecelis B Martines, Mia Mattioli
{"title":"Notes from the Field: Fatal Acanthamoeba Encephalitis in a Patient Who Regularly Used Tap Water in an Electronic Nasal Irrigation Device and a Continuous Positive Airway Pressure Machine at Home - New Mexico, 2023.","authors":"Julia C Haston, Ibne K Ali, Shantanu Roy, Alexis Roundtree, Jessica Hofstetter, Savannah Pierson, Emily Helmrich, Paul Torres, Kodi Lockey, Roosecelis B Martines, Mia Mattioli","doi":"10.15585/mmwr.mm7410a4","DOIUrl":"10.15585/mmwr.mm7410a4","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 10","pages":"179-180"},"PeriodicalIF":25.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal Case of Splash Pad-Associated Naegleria fowleri Meningoencephalitis - Pulaski County, Arkansas, September 2023.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-27 DOI: 10.15585/mmwr.mm7410a2
Theresa M Dulski, Forrest Montgomery, Jeanette M Ramos, Eric R Rosenbaum, Bobby L Boyanton, Courtney M Cox, Steven Dahl, Cole Kitchens, Terry Paul, Amy Kahler, Alexis Roundtree, Mia Mattioli, Michele C Hlavsa, Ibne K Ali, Shantanu Roy, Julia C Haston, Naveen Patil
{"title":"Fatal Case of Splash Pad-Associated Naegleria fowleri Meningoencephalitis - Pulaski County, Arkansas, September 2023.","authors":"Theresa M Dulski, Forrest Montgomery, Jeanette M Ramos, Eric R Rosenbaum, Bobby L Boyanton, Courtney M Cox, Steven Dahl, Cole Kitchens, Terry Paul, Amy Kahler, Alexis Roundtree, Mia Mattioli, Michele C Hlavsa, Ibne K Ali, Shantanu Roy, Julia C Haston, Naveen Patil","doi":"10.15585/mmwr.mm7410a2","DOIUrl":"10.15585/mmwr.mm7410a2","url":null,"abstract":"<p><p>A fatal case of primary amebic meningoencephalitis (PAM), an infection caused by Naegleria fowleri, was diagnosed in Arkansas in a young child in September 2023. A public health investigation was completed, with epidemiologic, laboratory, and environmental data suggesting that a splash pad (an interactive water play venue that sprays or jets water on users and has little or no standing water) with inadequately disinfected water was the most likely site of the patient's N. fowleri exposure. This case is the third occurrence of splash pad-associated PAM reported in the United States; all three cases involved inadequately disinfected water. PAM should be considered in patients with acute meningoencephalitis and a history of recent possible exposure to fresh water, including treated recreational water (e.g., in splash pads or pools), via the nasal passages. Proper design, construction, operation, and management of splash pads can help prevent illnesses, including N. fowleri infections. Increased awareness, collaboration, and communication among clinicians, hospitals, laboratories, CDC, health departments, the aquatics sector, and the public can help support N. fowleri infection identification, treatment, prevention, and control efforts.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 10","pages":"167-172"},"PeriodicalIF":25.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthetic Opioid and Stimulant Co-Involved Overdose Deaths by Occupation and Industry - United States, 2022. 2022 年美国按职业和行业分列的合成类阿片和兴奋剂共用过量死亡人数。
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-27 DOI: 10.15585/mmwr.mm7410a3
Eric W Lundstrom, Alexandria Macmadu, Andrea L Steege, Matthew Groenewold
{"title":"Synthetic Opioid and Stimulant Co-Involved Overdose Deaths by Occupation and Industry - United States, 2022.","authors":"Eric W Lundstrom, Alexandria Macmadu, Andrea L Steege, Matthew Groenewold","doi":"10.15585/mmwr.mm7410a3","DOIUrl":"10.15585/mmwr.mm7410a3","url":null,"abstract":"<p><p>The proportion of synthetic opioid overdose deaths co-involving stimulants has increased in the United States in recent years. Although persons who use opioids have reported increasing stimulant co-use to maintain workplace productivity and alertness, occupational patterns of co-involvement in fatal overdose have not been systematically investigated. In an exploratory study, data on overdose deaths involving synthetic opioids (e.g., fentanyl) from the 2022 National Vital Statistics System were analyzed to characterize patterns of stimulant co-involvement among U.S. residents aged 15-64 years, stratified by decedents' usual occupation and industry. Of 69,893 fatal synthetic opioid overdoses, 53.6% involved stimulants. Occupation and industry groups with the highest percentages of synthetic opioid overdose deaths co-involving psychostimulants with abuse potential (psychostimulants) were typically physically demanding (e.g., construction and extraction occupations), whereas categories with highest percentages of cocaine co-involvement were generally less physically strenuous (e.g., business and financial occupations); these patterns might reflect differences in desired drug effects, cost, and geographic availability. Work-related interventions might be useful in preventing the development of substance use disorder by decreasing rates of occupational injuries and workplace stress, connecting workers with substance use disorder to treatment resources, and reducing fatal overdose through harm reduction.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 10","pages":"173-178"},"PeriodicalIF":25.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Disability, Violence, HIV Status, and Risk Factors for HIV Among Adolescent Girls and Young Women - Eswatini, 2022.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-20 DOI: 10.15585/mmwr.mm7409a2
Ghenet Besera, Francis B Annor, Elizabeth A Swedo, Laura F Chiang, Sana N Charania, Phumzile Mndzebele, Michelle J Li, Jennifer Hegle, Anne Laterra, Robyn A Cree, Nozipho Nzuza-Motsa, Thobile Mkhonta, Kristopher Mills, Silke Felton, Greta M Massetti
{"title":"Functional Disability, Violence, HIV Status, and Risk Factors for HIV Among Adolescent Girls and Young Women - Eswatini, 2022.","authors":"Ghenet Besera, Francis B Annor, Elizabeth A Swedo, Laura F Chiang, Sana N Charania, Phumzile Mndzebele, Michelle J Li, Jennifer Hegle, Anne Laterra, Robyn A Cree, Nozipho Nzuza-Motsa, Thobile Mkhonta, Kristopher Mills, Silke Felton, Greta M Massetti","doi":"10.15585/mmwr.mm7409a2","DOIUrl":"10.15585/mmwr.mm7409a2","url":null,"abstract":"<p><p>Eswatini has made substantial progress responding to its HIV epidemic and reducing violence against children. However, adolescent girls and young women with disabilities might be at increased risk for experiencing violence and for HIV infection, compared with those without disabilities. Data from the 2022 Eswatini Violence Against Children and Youth Survey were analyzed to compare HIV infection and violence-related measures by functional disability status (e.g., difficulties in performing functional activities such as seeing, walking, or communicating) among adolescent girls and young women. In 2022, in Eswatini, 14.0% of adolescent girls and young women aged 13-24 years had a reported functional disability. Compared with those without a functional disability, adolescent girls and young women with a functional disability had higher lifetime prevalences of experiencing sexual, physical, and emotional violence. They were also more likely to know where to seek help for experiences of violence. After adjusting for sociodemographic characteristics, HIV testing and infection status, HIV risk factors, sexual risk behaviors, and HIV treatment and prevention services did not differ by functional disability status. Prioritizing accessible, disability-inclusive prevention programs and services might help reduce experiences of violence among adolescent girls and young women with disabilities. Partnering with disability-led and disability-serving organizations and directly with adolescent girls and young women with disabilities to plan and implement programs and services that are disability-inclusive could help ensure that adolescent girls and young women with disabilities are aware of and can access these resources.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 9","pages":"152-157"},"PeriodicalIF":25.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe - United States, August 2024.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-20 DOI: 10.15585/mmwr.mm7409a3
Elizabeth M Wendt, Farrell A Tobolowsky, Gerardo Priotto, Jose Ramon Franco, Rebecca Chancey
{"title":"Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe - United States, August 2024.","authors":"Elizabeth M Wendt, Farrell A Tobolowsky, Gerardo Priotto, Jose Ramon Franco, Rebecca Chancey","doi":"10.15585/mmwr.mm7409a3","DOIUrl":"10.15585/mmwr.mm7409a3","url":null,"abstract":"","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 9","pages":"158-159"},"PeriodicalIF":25.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Finding Among and Comprehensive Management of Household Contacts of Persons with Pulmonary Tuberculosis: a Pilot Project - Uganda, 2023-2024.
IF 25.4 1区 医学
MMWR. Morbidity and mortality weekly report Pub Date : 2025-03-20 DOI: 10.15585/mmwr.mm7409a1
Denis Mudoola, Pruthu Thekkur, Joseph Nsonga, Ritah Mande, Selma Dar Berger, Stavia Turyahabwe, Simon Muchuro, Proscovia Namuwenge, Moorine Sekadde, Deus Lukoye, Henry Luzze, John Paul Dongo, Anand Date, Riitta A Dlodlo, Odile Ferroussier-Davis, Macarthur Charles
{"title":"Case Finding Among and Comprehensive Management of Household Contacts of Persons with Pulmonary Tuberculosis: a Pilot Project - Uganda, 2023-2024.","authors":"Denis Mudoola, Pruthu Thekkur, Joseph Nsonga, Ritah Mande, Selma Dar Berger, Stavia Turyahabwe, Simon Muchuro, Proscovia Namuwenge, Moorine Sekadde, Deus Lukoye, Henry Luzze, John Paul Dongo, Anand Date, Riitta A Dlodlo, Odile Ferroussier-Davis, Macarthur Charles","doi":"10.15585/mmwr.mm7409a1","DOIUrl":"10.15585/mmwr.mm7409a1","url":null,"abstract":"<p><p>To help achieve the End TB Strategy target of a 90% reduction in tuberculosis (TB) incidence by 2030, member states of the United Nations High-Level Meetings on TB called for improving provision of TB preventive treatment (TPT) for household contacts of persons with TB, who are at increased risk for infection and disease. However, TPT use among household contacts worldwide remained at 21% in 2023. The International Union Against Tuberculosis and Lung Disease, the Uganda Ministry of Health, and CDC piloted a comprehensive approach for increasing case finding and TPT coverage among household contacts of persons with TB. During November 1, 2023-September 30, 2024, a total of 521 index patients with TB disease were registered at six health facilities in Uganda. Home visits to index patients identified 1,913 household contacts, 1,739 (91.0%) of whom underwent TB symptom screening at home; 321 (18.5%) reported TB symptoms. Of 309 (96.3%) persons with TB symptoms who were further evaluated, 284 (91.9%) provided a sputum specimen for laboratory testing, including 270 (84.1% of those with symptoms) who did so during the home visit; 214 (69.3%) underwent chest radiography. Overall, 80 TB cases were diagnosed; in 61 (76.3%) persons, the diagnosis was based on radiographic findings. Among 1,496 HHCs eligible for TPT, 1,239 (82.8%) initiated treatment and 1,178 (95.1%) completed it. Global scale-up of this approach might help reach global TB elimination goals.</p>","PeriodicalId":18637,"journal":{"name":"MMWR. Morbidity and mortality weekly report","volume":"74 9","pages":"145-151"},"PeriodicalIF":25.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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