Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.020
Álvaro Criado-Antón, Patricia Zunzunegui-Arroyo, Pablo Siso-García, David Fuentes-Castañón, Santiago Fernández-Menéndez
{"title":"Neuroborreliosis at the region of Asturias, Spain (2009-2022): Analysis of 38 cases.","authors":"Álvaro Criado-Antón, Patricia Zunzunegui-Arroyo, Pablo Siso-García, David Fuentes-Castañón, Santiago Fernández-Menéndez","doi":"10.1016/j.medcli.2024.09.020","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.020","url":null,"abstract":"<p><strong>Introduction: </strong>Diagnosis of neurological involvement in Lyme disease is based on two-step serological testing and cerebrospinal fluid pleocytosis. In Spain its incidence is much lower than in other European countries, being Asturias the region with the highest incidence. We tried to analyse the clinical and epidemiological aspects in the main hospital in Asturias.</p><p><strong>Material y methods: </strong>Retrospective observational study of patients admitted for Lyme disease in our center over 14years (2009-2022). Clinical, analytical and evolutionary variables were analyzed after one year. Active neuroborreliosis was diagnosed after registering pleocytosis and positive serologies at the cerebrospinal fluid.</p><p><strong>Results: </strong>108 episodes were analyzed, corresponding to 100 patients coded at discharge as Lyme disease. 58 episodes are discarded due to diagnostic or coding error. 51 episodes were considered active disease, being 38 diagnosed of neuroborreliosis. Tick bite recall and erythema were reported in 55.3% and 31.6% of patients. The most frequent neurological syndromes were radiculoneuritis (36.84%), bilateral facial palsy (13.56%), radiculoneuritis and bilateral facial palsy (10.52%) and multiple cranial mononeuropathy (10.52%), among others. 78.9% achieved a complete recovery, and 15.79% developed post-treatment Lyme disease syndrome.</p><p><strong>Discussion: </strong>Despite the high incidence of Lyme disease in Asturias, the cases based on hospital admission that can be classified as active disease are lower than those published based on hospital coding. The main source of diagnostic error is positive serological results, without other clinical context, especially in patients studied for cognitive impairment or encephalopathy.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.011
Elena Villanueva Sánchez, Karen Rivero García, Pilar Fraile Gómez
{"title":"Recurring peritonitis due to Tsukamurella paurometabola in a patient on automated peritoneal dialysis.","authors":"Elena Villanueva Sánchez, Karen Rivero García, Pilar Fraile Gómez","doi":"10.1016/j.medcli.2024.09.011","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.011","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.012
Lluís Cirera, Diego Salmerón
{"title":"Dysfunctional insertion of the electronic medical death certificate in the official statistics of causes of death.","authors":"Lluís Cirera, Diego Salmerón","doi":"10.1016/j.medcli.2024.09.012","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.012","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.014
Aldo Medina Gamero
{"title":"Ethics and challenges of artificial intelligence in healthcare.","authors":"Aldo Medina Gamero","doi":"10.1016/j.medcli.2024.09.014","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.014","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.018
Olga Rubio, Marc Vila, Manel Escobar, Alvar Agusti
{"title":"How could artificial intelligence improve patient experience in the ambulatory setting? Reflections from the JANUS group.","authors":"Olga Rubio, Marc Vila, Manel Escobar, Alvar Agusti","doi":"10.1016/j.medcli.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.018","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.016
Pablo Solís Sánchez, Sara Nieto Martínez, Javier Pardo Lledias
{"title":"Panhypopituitarism and diabetes insipidus secondary to hypothalamic glioblastoma multiforme.","authors":"Pablo Solís Sánchez, Sara Nieto Martínez, Javier Pardo Lledias","doi":"10.1016/j.medcli.2024.09.016","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.016","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.022
Rita González Resina, Mar Herrero Gutiérrez, Gonzalo Caballero Navarro
{"title":"Thyroid abscess due to Escherichia coli in a multiple myeloma patient.","authors":"Rita González Resina, Mar Herrero Gutiérrez, Gonzalo Caballero Navarro","doi":"10.1016/j.medcli.2024.09.022","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.022","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-22DOI: 10.1016/j.medcli.2024.09.005
Oscar Caso Maestro, Virginia García Moreno, Iago Justo Alonso, Alberto Marcacuzco Quinto, Jose María Aguado, Carmelo Loinaz Segurola, Carlos Jiménez Romero
{"title":"Outcomes of liver transplantation with donors older than 80 years in HCV patients treated with direct-action antivirals vs. non-HCV patients.","authors":"Oscar Caso Maestro, Virginia García Moreno, Iago Justo Alonso, Alberto Marcacuzco Quinto, Jose María Aguado, Carmelo Loinaz Segurola, Carlos Jiménez Romero","doi":"10.1016/j.medcli.2024.09.005","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.005","url":null,"abstract":"<p><strong>Background: </strong>Multiple studies have shown good results with the use of octogenarian donors in non-HCV recipients and its use is universally accepted worldwide. There are no studies analyzing differences between hepatitis C virus (HCV) and non-HCV recipients transplanted with donors≥80 years in the direct-action antivirals (DAA) period. The rate of liver transplantation (LT) using old donors is still low, and a change in the acceptance of these grafts could increase the liver pool available for LT.</p><p><strong>Material and methods: </strong>Since the introduction of DAA therapy in our hospital in January 2014 to May 2022, 457 LT were performed, and 74 (16.2%) of these patients underwent LT with donors≥80 years. A cohort study was carried-out comparing 15 HCV-positive recipients vs. 59 HCV-negative patients during the period of the study.</p><p><strong>Results: </strong>Recipients were younger in the non-HCV group. MELD and subsequently DMELD were higher in non-HCV group. Nevertheless, the association of hepatocellular carcinoma (HCC) with HCV cirrhosis was higher than with non-HCV cirrhosis (86.7% vs. 28.8%; p<0.001), but there were no recurrences within HCV group and only 1 case in the non-HCV group. The 1-, 3-, and 5-years patient and graft survival were similar in both groups. Recipient age and intraoperative transfusion requirements were predictors of graft survival [(HR 1.10, 95CI 1.01-1.21; p=0.03) and (HR 1.03, 95CI 1.01-1.05; p<0.001), respectively].</p><p><strong>Conclusions: </strong>In conclusion, the use of octogenarian donors was a safe alternative to younger donors in HCV recipients requiring LT in the era of DAA with similar results to those obtained in non-HCV patients.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}