Medicina Clinica最新文献_第10页

Acute organophosphorus pesticide poisoning with hepatic portal venous gas 急性有机磷农药中毒伴肝门静脉气体

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-23 DOI: 10.1016/j.medcli.2025.106967

Xinsen Chen , Ting Jiang , Lu Zhang

引用次数: 0

Diagnostic value of blood coagulation index in obstetric antiphospholipid syndrome and its subtypes 凝血指标对产科抗磷脂综合征及其亚型的诊断价值

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106997

Xuan Qi , Xiaomeng Li , Yan Han , Lingyan Lei , Huifang Guo

{"title":"Diagnostic value of blood coagulation index in obstetric antiphospholipid syndrome and its subtypes","authors":"Xuan Qi , Xiaomeng Li , Yan Han , Lingyan Lei , Huifang Guo","doi":"10.1016/j.medcli.2025.106997","DOIUrl":"10.1016/j.medcli.2025.106997","url":null,"abstract":"<div><h3>Objective</h3><div>To characterize blood coagulation index in obstetric antiphospholipid syndrome (OAPS) and its subtypes, analyzing correlations with immunological indices and diagnostic value.</div></div><div><h3>Methods</h3><div>A retrospective analysis was performed on OAPS patients treated at the Department of Rheumatology and Immunology, Second Hospital of Hebei Medical University, from September 2023 to March 2024. Healthy women of the same age range were matched for comparison.</div></div><div><h3>Results</h3><div>A total of 102 OAPS patients and 80 matched healthy controls were included. OAPS patients exhibited significantly lower levels of complement factors C3 and C4, coagulation factors V and VII activities, and protein S activity (<em>p</em>  <0.05). Among OAPS patients, criteria OAPS cases showed significantly higher anti-β2-GPI antibodies and anticardiolipin antibody levels (<em>p</em>  <0.01).</div></div><div><h3>Conclusion</h3><div>Correlations were found between immunological indices (ANA, complement C3, anti-β2-GPI) and coagulation indices (TAT, APTT). ANA, complement C3, anti-β2-GPI antibodies, and TAT were identified as risk factors for predicting OAPS. Blood coagulation and immune indices correlate in OAPS. Detecting these indices may provide diagnostic value for OAPS and its subtypes.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 1","pages":"Article 106997"},"PeriodicalIF":2.6,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relapsing polychondritis 复发polychondritis

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106985

Makram Tbini , Ines Riahi , Chaima Ben Ammar , Mamia Ben Salah

引用次数: 0

Whipple's disease mimicking systemic lupus erythematosus 类似系统性红斑狼疮的惠普尔氏病

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106960

Laia de Daniel , Xavier Sanjuan , Javier Narváez

引用次数: 0

Fatal hemoptysis due to massive cavitation of lung metastases in a patient with adenoid cystic carcinoma treated with lenvatinib 在lenvatinib治疗的腺样囊性癌患者中，由于肺转移的大量空化而致致命性咯血

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106955

Luis Gorospe , Yolanda Lage-Alfranca , Ainara Soria-Rivas , Abel González-Huete

引用次数: 0

Prevalencia de enfermedad vascular subclínica en función del riesgo vascular estimado y la presencia de síndrome metabólico 亚临床血管疾病的患病率与估计的血管风险和代谢综合征的存在有关

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106987

José María Mostaza , Carlos Lahoz , Miguel A. Salinero-Fort , Eva Estirado , Francisca García-Iglesias , Teresa González Alegre , Víctor Cornejo , en representación de los investigadores del estudio ESPREDIA

{"title":"Prevalencia de enfermedad vascular subclínica en función del riesgo vascular estimado y la presencia de síndrome metabólico","authors":"José María Mostaza , Carlos Lahoz , Miguel A. Salinero-Fort , Eva Estirado , Francisca García-Iglesias , Teresa González Alegre , Víctor Cornejo , en representación de los investigadores del estudio ESPREDIA","doi":"10.1016/j.medcli.2025.106987","DOIUrl":"10.1016/j.medcli.2025.106987","url":null,"abstract":"<div><div>Most vascular complications occur in persons with a low or moderate calculated vascular risk. We have evaluated the added prediction of the metabolic syndrome (MS) to the presence of subclinical vascular disease (SVD), beyond that estimated by the cardiovascular risk calculation.</div></div><div><h3>Patients and methods</h3><div>Cross-sectional population-based study, in 1,061 subjects aged 45 to 75 years, without diabetes or known vascular disease, randomly selected from the Primary Care registries of Madrid (Spain). Vascular risk was calculated using SCORE2 and SCORE2-OP, the presence of MS was determined, and the prevalence of SVD was established by quantification of carotid plaques and ankle-brachial index.</div></div><div><h3>Results</h3><div>Of the included population, 40.2% was at low/moderate risk, 54.5% at high risk and 5.3% at very high risk. A total of 36.1% met the criteria for MS. The prevalence of SVD was 27.7, 50.1 and 71.4% in subjects at low/moderate, high and very high risk without MS, and 42.5, 62.6 and 78.6% if they had MS, respectively. The association of MS with the presence of EVS was independent of its separate components. A total of 23.1% of the participants were receiving statin treatment. Statin use was independent of the calculated cardiovascular risk and much higher in subjects with MS (38.6 vs. 12.8%).</div></div><div><h3>Conclusion</h3><div>Subjects with MS have a high prevalence of SVD, independent of the estimated risk. The use of statins is more prevalent in subjects with the MS, and is independent of the estimated cardiovascular risk.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 2","pages":"Article 106987"},"PeriodicalIF":2.6,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platypnea-orthodeoxia syndrome in an elderly patient with undiagnosed patent foramen ovale 未确诊卵圆孔未闭的老年患者肺动脉-正氧综合征1例

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.107008

Francisco Epelde

引用次数: 0

Efectividad de la timectomía en la evolución de la miastenia gravis: análisis de 21 pacientes 乳房切除术对重症肌无力发展的影响：分析21例患者

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106957

Sofía Corbaz , Andrea Savransky , Nadia Gaeto , Adolfo Gallo , Marcelo Barrenechea , María Soledad Monges

{"title":"Efectividad de la timectomía en la evolución de la miastenia gravis: análisis de 21 pacientes","authors":"Sofía Corbaz , Andrea Savransky , Nadia Gaeto , Adolfo Gallo , Marcelo Barrenechea , María Soledad Monges","doi":"10.1016/j.medcli.2025.106957","DOIUrl":"10.1016/j.medcli.2025.106957","url":null,"abstract":"<div><h3>Introduction</h3><div>Myasthenia gravis is part of a group of neuromuscular junction disorders. Thymectomy has been shown to be effective for its clinical control. The aim of this study was to assess the usefulness and safety of thymectomy in children with myasthenia gravis.</div></div><div><h3>Methods</h3><div>An analytical, retrospective, longitudinal study was conducted by reviewing the medical records of 21 patients with myasthenia gravis who underwent thymectomy and were followed-up for one year post-surgery. The variables assessed included the Myasthenia Gravis Activities of Daily Living score, pyridostigmine dose, corticosteroid dose, and myasthenia gravis exacerbations immediately before and up to one year after the surgery.</div></div><div><h3>Results</h3><div>The activities of daily living score significantly improved at 12 months (p=0.002). Crises decreased within 3 months post-surgery; this trend was maintained at 12 months (p=0.0003). However, the reductions in pyridostigmine (p=0.147) and corticosteroid therapy (p=0.11) at 12 months did not reach statistical significance.</div></div><div><h3>Conclusions</h3><div>Thymectomy showed benefits, including improved scores on the Myasthenia Gravis Activities of Daily Living Scale and a reduction in the frequency of myasthenia gravis exacerbations/crises. These findings show that thymectomy is a safe and valid option to consider for pediatric patients who have not responded to the first-line treatment.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 2","pages":"Article 106957"},"PeriodicalIF":2.6,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Helicobacter pylori y enfermedad gástrica 幽门螺杆菌gástrica

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106974

Javier P. Gisbert

引用次数: 0

Diferencias en el perfil clínico entre hombres y mujeres con apneas obstructivas del sueño 男性和女性阻塞性睡眠呼吸暂停患者的临床情况差异

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-05-22 DOI: 10.1016/j.medcli.2025.106975

Nuria Roger-Casals , Ana Maria Muñoz-Fernández , Cristina Muñoz-Pindado

引用次数: 0