Medicina Clinica最新文献

{"title":"Enterocolic lymphocytic phlebitis: Clinical insights from a literature review","authors":"Ying Zhao ,&nbsp;Xiaoying Zhang ,&nbsp;Yongsheng Li ,&nbsp;Jinhua He ,&nbsp;Zeping Han","doi":"10.1016/j.medcli.2025.107065","DOIUrl":"10.1016/j.medcli.2025.107065","url":null,"abstract":"<div><h3>Objective</h3><div>Enterocolic lymphocytic phlebitis (ELP) is a rare venous-specific gastrointestinal inflammation with challenging preoperative diagnosis. We aimed to characterize its clinicopathological spectrum.</div></div><div><h3>Patients and methods</h3><div>This narrative review synthesizes evidence from 85 published cases (9–81 years) from 50 articles to characterize ELP's clinicopathological features and diagnostic pitfalls, along with its differentiation from other vasculitides, such as Behcet's disease, systemic lupus erythematosus, mesenteric inflammatory veno-occlusive disease, idiopathic myointimal hyperplasia of the mesenteric veins and IgG4-related diseases.</div></div><div><h3>Results</h3><div>ELP has a wide range of clinical and histological presentations, it predominantly affects the right colon/small bowel, mimicking acute abdomen. Diagnosis relies on postoperative histopathology showing venular lymphocytic infiltration.</div></div><div><h3>Conclusion</h3><div>ELP represents a underdiagnosed clinicopatologic entity, a diagnosis of ELP is predominantly made after histological resection.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 5","pages":"Article 107065"},"PeriodicalIF":2.6,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid remission of SAPHO syndrome with secukinumab","authors":"Guangliang Wei,&nbsp;Huidong Chen,&nbsp;Jie Chen","doi":"10.1016/j.medcli.2025.107050","DOIUrl":"10.1016/j.medcli.2025.107050","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107050"},"PeriodicalIF":2.6,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of Kikuchi-Fujimoto disease initially presented as aseptic meningitis","authors":"Jinliang Deng ,&nbsp;Lin Shen ,&nbsp;Jingzhe Han","doi":"10.1016/j.medcli.2025.107039","DOIUrl":"10.1016/j.medcli.2025.107039","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107039"},"PeriodicalIF":2.6,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad clínica de la monitorización mediante pupilometría cuantitativa en pacientes con daño cerebral agudo","authors":"Eusebio Campos ,&nbsp;Eva Esther Tejerina Álvarez ,&nbsp;José Ángel Lorente Balanza","doi":"10.1016/j.medcli.2025.107046","DOIUrl":"10.1016/j.medcli.2025.107046","url":null,"abstract":"<div><div>Assessment of the pupillary reflex to light is essential in patients with acute brain injury, as pupillary abnormalities are associated with neurological impairment and elevated intracranial pressure. Manual assessment by headlamp is inaccurate, whereas quantitative pupillometry provides objective and accurate measurements of pupillary size and reactivity, anticipating severe neurological deterioration and allowing early intervention in life-threatening situations. The pupillary neurological index, a variable derived from automated pupillometry, correlates with intracranial pressure, allows monitoring of therapeutic response in trauma and status epilepticus, is associated with the severity of neurological damage and may serve as a predictor of unfavourable neurological prognosis. The aim of this review is to summarise the evidence on the clinical utility of monitoring by quantitative pupillometry in neurological emergencies.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107046"},"PeriodicalIF":2.6,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign familial pemphigus","authors":"Álvaro Mínguez Contreras,&nbsp;Enrique García Soler,&nbsp;Cristina Albanell Fernández","doi":"10.1016/j.medcli.2025.107063","DOIUrl":"10.1016/j.medcli.2025.107063","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 5","pages":"Article 107063"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agradecimientos","authors":"","doi":"10.1016/S0025-7753(25)00320-3","DOIUrl":"10.1016/S0025-7753(25)00320-3","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"164 12","pages":"Article 107092"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144330035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Livedo racemosa secundaria a embolización de la arteria genicular en una paciente con artrosis de rodilla","authors":"Lula María Nieto Benito,&nbsp;Pablo Fonda Pascual,&nbsp;Loreto Carrasco Santos","doi":"10.1016/j.medcli.2025.107071","DOIUrl":"10.1016/j.medcli.2025.107071","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107071"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major adverse cardiovascular events among patients with type 2 diabetes mellitus: A prospective study","authors":"David Martín-Enguix ,&nbsp;Juan Carlos Aguirre Rodríguez ,&nbsp;Abraham Hidalgo Rodríguez ,&nbsp;María Guisasola Cárdenas ,&nbsp;María Sánchez Cambronero ,&nbsp;María Nieves Generoso Torres ,&nbsp;Manuel Joaquín Castillo ,&nbsp;Francisco José Amaro-Gahete","doi":"10.1016/j.medcli.2025.107028","DOIUrl":"10.1016/j.medcli.2025.107028","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Large-scale studies (UKPDS and CALIBER) reported annual major adverse cardiovascular events (MACE) rates of 2.5–2.6% occurrence in patients with type 2 diabetes mellitus (T2D). However, data for different geographical locations in Spain are unknown. The aim of this study was to investigate the most common causes of MACE and the factors that contribute to its occurrence in patients with DM2 living in southern Spain.</div></div><div><h3>Methods</h3><div>In this cohort study, 297 patients with T2D were monitored over 49 months to assess the occurrence of MACE (i.e., stroke, myocardial infarction, and/or cardiovascular death). Sociodemographic and clinical data (including cardiovascular disease risk factors and initial treatments) were collected to examine their impact on the incidence of MACE.</div></div><div><h3>Results</h3><div>The mean age of the cohort was 67.7 years, with a male predominance (53.3%) and an average T2D duration of 8.8 years. Over the 4-year follow-up, 10.7% of patients experienced a MACE, with myocardial infarction and cardiovascular death being the most prevalent events (both 38.7%). In multivariate analysis, each additional year of T2D evolution was associated with a 15% increased risk of MACE (HR<!--> <!-->=<!--> <!-->1.150 [1.006–1.314], <em>p</em> <!-->=<!--> <!-->0.041), while each unit increase in estimated glomerular filtration rate (eGFR) was linked to a 3.3% risk reduction (HR<!--> <!-->=<!--> <!-->0.967 [0.938–0.997], <em>p</em> <!-->=<!--> <!-->0.033).</div></div><div><h3>Conclusion</h3><div>Myocardial infarction and cardiovascular death were the leading causes of MACE in T2D patients over a 4-year follow-up. Longer T2D duration and lower eGFR were the most significant risk factors. These findings underscore the need of closer monitoring and intensive treatment in patients with long-standing T2D and/or impaired renal function.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107028"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalloped pupil in a patient with hereditary amyloidosis transthyretin","authors":"Alex de Novais Batista,&nbsp;João Eudes Magalhães","doi":"10.1016/j.medcli.2025.107069","DOIUrl":"10.1016/j.medcli.2025.107069","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107069"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fascitis eosinofílica","authors":"Iago Pinal-Fernández ,&nbsp;José César Milisenda ,&nbsp;Albert Selva-O’Callaghan","doi":"10.1016/j.medcli.2025.107066","DOIUrl":"10.1016/j.medcli.2025.107066","url":null,"abstract":"<div><div>Eosinophilic fasciitis is a rare scleroderma-like syndrome of unknown cause. It is characterized by painful induration and progressive thickening of the muscular fascia and subcutaneous tissue of the limbs and trunk. The most common laboratory findings include peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate. The diagnosis is confirmed through a full-thickness wedge biopsy of the affected skin, revealing inflammation and thickening of the deep fascia.</div><div>The differential diagnosis includes scleroderma, morphea, myofasciitis in graft-versus-host disease, and epidemic fasciitis syndromes caused by toxins, such as eosinophilia-myalgia syndrome and toxic oil syndrome. Although the diagnosis is based on clinical, laboratory, and histological findings, no universal diagnostic criteria exist. Glucocorticoids are the standard treatment, although some patients may improve spontaneously.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107066"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}