Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.018
Olga Rubio, Marc Vila, Manel Escobar, Alvar Agusti
{"title":"How could artificial intelligence improve patient experience in the ambulatory setting? Reflections from the JANUS group.","authors":"Olga Rubio, Marc Vila, Manel Escobar, Alvar Agusti","doi":"10.1016/j.medcli.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.018","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.016
Pablo Solís Sánchez, Sara Nieto Martínez, Javier Pardo Lledias
{"title":"Panhypopituitarism and diabetes insipidus secondary to hypothalamic glioblastoma multiforme.","authors":"Pablo Solís Sánchez, Sara Nieto Martínez, Javier Pardo Lledias","doi":"10.1016/j.medcli.2024.09.016","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.016","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-23DOI: 10.1016/j.medcli.2024.09.022
Rita González Resina, Mar Herrero Gutiérrez, Gonzalo Caballero Navarro
{"title":"Thyroid abscess due to Escherichia coli in a multiple myeloma patient.","authors":"Rita González Resina, Mar Herrero Gutiérrez, Gonzalo Caballero Navarro","doi":"10.1016/j.medcli.2024.09.022","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.022","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-22DOI: 10.1016/j.medcli.2024.09.005
Oscar Caso Maestro, Virginia García Moreno, Iago Justo Alonso, Alberto Marcacuzco Quinto, Jose María Aguado, Carmelo Loinaz Segurola, Carlos Jiménez Romero
{"title":"Outcomes of liver transplantation with donors older than 80 years in HCV patients treated with direct-action antivirals vs. non-HCV patients.","authors":"Oscar Caso Maestro, Virginia García Moreno, Iago Justo Alonso, Alberto Marcacuzco Quinto, Jose María Aguado, Carmelo Loinaz Segurola, Carlos Jiménez Romero","doi":"10.1016/j.medcli.2024.09.005","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.09.005","url":null,"abstract":"<p><strong>Background: </strong>Multiple studies have shown good results with the use of octogenarian donors in non-HCV recipients and its use is universally accepted worldwide. There are no studies analyzing differences between hepatitis C virus (HCV) and non-HCV recipients transplanted with donors≥80 years in the direct-action antivirals (DAA) period. The rate of liver transplantation (LT) using old donors is still low, and a change in the acceptance of these grafts could increase the liver pool available for LT.</p><p><strong>Material and methods: </strong>Since the introduction of DAA therapy in our hospital in January 2014 to May 2022, 457 LT were performed, and 74 (16.2%) of these patients underwent LT with donors≥80 years. A cohort study was carried-out comparing 15 HCV-positive recipients vs. 59 HCV-negative patients during the period of the study.</p><p><strong>Results: </strong>Recipients were younger in the non-HCV group. MELD and subsequently DMELD were higher in non-HCV group. Nevertheless, the association of hepatocellular carcinoma (HCC) with HCV cirrhosis was higher than with non-HCV cirrhosis (86.7% vs. 28.8%; p<0.001), but there were no recurrences within HCV group and only 1 case in the non-HCV group. The 1-, 3-, and 5-years patient and graft survival were similar in both groups. Recipient age and intraoperative transfusion requirements were predictors of graft survival [(HR 1.10, 95CI 1.01-1.21; p=0.03) and (HR 1.03, 95CI 1.01-1.05; p<0.001), respectively].</p><p><strong>Conclusions: </strong>In conclusion, the use of octogenarian donors was a safe alternative to younger donors in HCV recipients requiring LT in the era of DAA with similar results to those obtained in non-HCV patients.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-19DOI: 10.1016/j.medcli.2024.10.001
Josep Arimany-Manso, Francesc Torralba, Ana Isabel Lima, María Die Trill
{"title":"A comprehensive approach to end-of-life care. Medical-legal, ethical, social, psychological and care aspects.","authors":"Josep Arimany-Manso, Francesc Torralba, Ana Isabel Lima, María Die Trill","doi":"10.1016/j.medcli.2024.10.001","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.10.001","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increasing prevalence of psoriasis in Spain: A population-based study (2018-2022).","authors":"Lucía Cayuela, José-Juan Pereyra-Rodríguez, Juan-Carlos Hernández-Rodríguez, Lourdes Rodríguez Fernandez-Freire, Aurelio Cayuela","doi":"10.1016/j.medcli.2024.08.019","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.08.019","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the prevalence of psoriasis in Spain from 2018 to 2022 and analyze trends by sex and age groups.</p><p><strong>Methods: </strong>We used the Primary Care Clinical Database (BDCAP) to identify individuals coded with psoriasis (S91) during the study period. Population data for calculating rates was obtained from the Primary Care Information System (SIAP). Crude, age- and sex-specific, and standardized prevalence rates were calculated. Joinpoint analysis assessed annual percentage change (APC) in prevalence.</p><p><strong>Results: </strong>The estimated psoriasis prevalence in Spain in 2022 was 1.9%. Psoriasis prevalence increased substantially by 43.3% (from 692,317 to 991,832 cases) over the study period. We observed a clear increase in both crude and standardized prevalence rates for men (7.2% annual increase) and women (8.3% annual increase) throughout the study period. Men consistently had slightly higher prevalence rates than women. Prevalence increased with age, reaching a peak in the 70-74 age group for men and 60-64 for women, before declining in older age groups.</p><p><strong>Conclusions: </strong>This study revealed a concerning increase in psoriasis prevalence in Spain, independent of population aging. Increased disease awareness, improved diagnostics, and greater treatment seeking behavior are potential explanations. Further research is needed to explore the underlying causes of this rise and inform public health interventions.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-18DOI: 10.1016/j.medcli.2024.10.002
Alejandro Blanco-Verea, Ángel Carracedo, María Brion
{"title":"Challenges of genetics in the diagnosis of sudden cardiac death. Interest of forensic and legal medicine.","authors":"Alejandro Blanco-Verea, Ángel Carracedo, María Brion","doi":"10.1016/j.medcli.2024.10.002","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.10.002","url":null,"abstract":"<p><p>Sudden cardiac death is the leading cause of death in developed countries and a small but significant number of cases cannot be explained after a thorough autopsy process. Cases of sudden cardiac death in people under 40years of age are mainly due to structural heart disease or cardiomyopathies and arrhythmogenic diseases or channelopathies. In these cases, the search for associated genetic factors through molecular autopsy may help to find the cause of unexplained sudden cardiac death, through genetic diagnosis of previously undiagnosed channelopathies or cardiomyopathies. The finding of genetic variants classified as pathogenic associated with cardiac pathology would conclude the autopsy result and provide the possibility of genetic screening in other family members.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-15DOI: 10.1016/j.medcli.2024.04.030
Javier Velasco Montes , Silvia González Díez , Elena Rivas Cilleros
{"title":"¿Se tiene en cuenta la ingesta de etanol?","authors":"Javier Velasco Montes , Silvia González Díez , Elena Rivas Cilleros","doi":"10.1016/j.medcli.2024.04.030","DOIUrl":"10.1016/j.medcli.2024.04.030","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"163 9","pages":"Page 475"},"PeriodicalIF":2.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2024-11-15DOI: 10.1016/j.medcli.2024.06.003
Robert Güerri-Fernández , Josep Benet , César Vargas
{"title":"Aspectos medicolegales en las enfermedades infecciosas","authors":"Robert Güerri-Fernández , Josep Benet , César Vargas","doi":"10.1016/j.medcli.2024.06.003","DOIUrl":"10.1016/j.medcli.2024.06.003","url":null,"abstract":"<div><div>This article reviews the medico-legal aspects associated with infectious diseases, highlighting their complexity and the challenges they pose. Infectious diseases cause not only an increase in morbidity and mortality in the healthcare setting but also involve complex legal issues. Healthcare-Associated Infections (HAIs) represent a growing risk with the increase in invasive procedures and can lead to patient complications and legal claims against healthcare professionals and institutions. The consequences of medical malpractice in this context are discussed, such as diagnostic delays, inappropriate use of treatments, and lack of adequate testing, which can have serious sequelae or even result in the patient's death.</div><div>The review focuses on highlighting the importance of prevention, considering that healthcare-associated infections can be difficult to avoid, posing complex legal challenges.</div><div>It concludes that managing infectious diseases and their legal consequences requires careful consideration of clinical practice guidelines, prevention and control strategies, and effective communication with patients. An integrated and evidence-based approach is advocated to address these challenges, emphasizing continuous education, the use of advanced diagnostic technologies, and interdisciplinary collaboration.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"163 9","pages":"Pages e98-e102"},"PeriodicalIF":2.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}