Medicina ClinicaPub Date : 2025-01-11DOI: 10.1016/j.medcli.2024.11.008
David González Falcón, Leticia Gómez-Sánchez, Marta Gómez-Sánchez, Emiliano Rodríguez-Sánchez, Olaya Tamayo-Morales, Cristina Lugones-Sánchez, Susana González-Sánchez, Moises Diaz, Manuel A Gómez-Marcos
{"title":"Evolution of arterial stiffness and association with cardiovascular risk factors in the Spanish population. Follow-up EVA.","authors":"David González Falcón, Leticia Gómez-Sánchez, Marta Gómez-Sánchez, Emiliano Rodríguez-Sánchez, Olaya Tamayo-Morales, Cristina Lugones-Sánchez, Susana González-Sánchez, Moises Diaz, Manuel A Gómez-Marcos","doi":"10.1016/j.medcli.2024.11.008","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.11.008","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>To analyse the increase of arterial stiffness over a five-year period and its relationship with cardiovascular risk factors and sex-based differences in a Spanish population without cardiovascular disease.</p><p><strong>Methods: </strong>Longitudinal study. Analysis of the increase in arterial stiffness measures evaluated with SphygmoCor and Vasera of 480 subjects followed for 5 years of the 501 subjects included in the baseline evaluation, selected through random sampling stratified by age and sex, mean age of 55.9 years, 50.3% women.</p><p><strong>Results: </strong>Increases per year: carotid-femoral pulse wave velocity (cf-PWV), 0.22 (SD 0.36) m/sec, brachial-ankle pulse wave velocity (ba-PWV), 0.18 (SD 0.30) m/sec, Cardio-Ankle Vascular Index (CAVI), 0.04 (SD 0.18) and Central Augmentation Index (CAI), 0.38 (SD 2.66). Multiple regression, increases in cf-PWV and ba-PWV showed an association with mean arterial pressure in global (β=0.02; β=-0.02) and in men (β=0.02; β=-0.03). In women, increases in ba-PWV and CAVI showed a negative association with BMI (β=-0.06; β=--0.03).</p><p><strong>Conclusions: </strong>The four measures of arterial stiffness increase over five years globally and by sex. These increases differ according to the measure used, age, sex and associated cardiovascular risk factors. Hypertensive people has greater increases in ba-PWV in global and by sex. The average blood pressure is associated with increases in cf-PWV and ba-PWV in global and in men. BMI is negatively associated with increases in ba-PWV and CAVI in women. Study registered at ClinicalTrials.gov. (NCT02623894).</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-06-25DOI: 10.1016/j.medcli.2024.03.031
Javier de la Iglesia Martin, Marta Alegre, Jose Manuel Mascaró Galy
{"title":"[Pyoderma gangrenosum and IgA Myeloma].","authors":"Javier de la Iglesia Martin, Marta Alegre, Jose Manuel Mascaró Galy","doi":"10.1016/j.medcli.2024.03.031","DOIUrl":"10.1016/j.medcli.2024.03.031","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"50-51"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141457929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-10-15DOI: 10.1016/j.medcli.2024.08.002
Jose Alberto de Agustín, Orlando Figueroa, Carmen Olmos Blanco, Eduardo Pozo Osinalde, Patricia Mahia Casado, María Luaces, María Rivadeneira, Pedro Marcos-Alberca, Jose Juan Gómez de Diego, Luis Collado Yurrita, Antonio Fernández-Ortiz, Julián Villacastín
{"title":"[Phenotype of severe tricuspid regurgitation induced by intracardiac pacing devices].","authors":"Jose Alberto de Agustín, Orlando Figueroa, Carmen Olmos Blanco, Eduardo Pozo Osinalde, Patricia Mahia Casado, María Luaces, María Rivadeneira, Pedro Marcos-Alberca, Jose Juan Gómez de Diego, Luis Collado Yurrita, Antonio Fernández-Ortiz, Julián Villacastín","doi":"10.1016/j.medcli.2024.08.002","DOIUrl":"10.1016/j.medcli.2024.08.002","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Tricuspid regurgitation (TR) induced by the implantation of cardiac implantable electronic devices (CIED) is an increasingly common cause of severe TR. Our aim was to describe the echocardiographic phenotypic characteristics of CIED-induced severe TR.</p><p><strong>Methods: </strong>Retrospective cohort study that included patients with severe TR related to CIED diagnosed in the cardiac imaging unit of a Spanish tertiary hospital.</p><p><strong>Results: </strong>37 patients with severe TR induced by lead/electrode interference formed our study group. TR was predominantly severe (68%), followed by massive (21%) and torrential (11%). The leaflet most affected by the interference was the septal. 58% of the sample presented severe dilatation of the right atrium (RA) (mean RA area 28cm<sup>2</sup>). Mean tricuspid annulus measurement was 42mm. The usual parameters for quantifying RV systolic function were on average within the normal range (TAPSE mean 19mm, S' wave 10mm, FAC 41%), while global RV strain (RVGLS -15%) and free wall strain (RVFWLS -19%) were found reduced. An incipient degree of ventricular/pulmonary arterial uncoupling was evident (mean TAPSE/PSAP 0.34, SGLVD/PSAP 0.27%/mmHg).</p><p><strong>Conclusions: </strong>Our patients with CIED-induced severe TR are characterized by a heterogeneous phenotype with a high prevalence of severe RA and tricuspid annulus dilatation. RVGLS, RVFWLS, and arterial ventricular coupling were the most sensitive parameters for early assessment of RV systolic dysfunction.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"10-15"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-10-09DOI: 10.1016/j.medcli.2024.07.014
Juan de Dios García Díaz, Javier Balsa Vázquez
{"title":"[Myhre syndrome: case report].","authors":"Juan de Dios García Díaz, Javier Balsa Vázquez","doi":"10.1016/j.medcli.2024.07.014","DOIUrl":"10.1016/j.medcli.2024.07.014","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"46-47"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-07-16DOI: 10.1016/j.medcli.2024.05.014
Victoria Contreras-Bolívar, María Carmen Andreo-López, Manuel Muñoz-Torres
{"title":"Characterization of bone disease in cystic fibrosis.","authors":"Victoria Contreras-Bolívar, María Carmen Andreo-López, Manuel Muñoz-Torres","doi":"10.1016/j.medcli.2024.05.014","DOIUrl":"10.1016/j.medcli.2024.05.014","url":null,"abstract":"<p><p>With the increased life expectancy of people with cystic fibrosis (CF), clinical attention has focused on prevention and treatment of non-pulmonary comorbidities. CF-related bone disease (CFBD) is a common complication and leads to increased fracture rates. Dual energy X-ray absorptiometry (DXA) is the recommended and gold standard technique to identify and monitor bone health. However, DXA has limitations because of its two-dimensional nature. Complementary tools to DXA are available, such as trabecular bone score (TBS) and vertebral fracture assessment (VFA). Quantitative computed tomography (QCT), magnetic resonance imaging (MRI) and quantitative ultrasound (QUS) may also be useful.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"23-29"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-08-29DOI: 10.1016/j.medcli.2024.05.020
Shanshan Liang, Li Zhang, Chuanmin Tao
{"title":"Atypical POEMS syndrome: Report of a patient.","authors":"Shanshan Liang, Li Zhang, Chuanmin Tao","doi":"10.1016/j.medcli.2024.05.020","DOIUrl":"10.1016/j.medcli.2024.05.020","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"40-41"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142109357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-10-19DOI: 10.1016/j.medcli.2024.07.010
Myrian González Álvarez, Ana Latorre Díez, Miguel Ángel Núñez Viejo
{"title":"[Stercoraceal colitis as a complication of chronic constipation].","authors":"Myrian González Álvarez, Ana Latorre Díez, Miguel Ángel Núñez Viejo","doi":"10.1016/j.medcli.2024.07.010","DOIUrl":"10.1016/j.medcli.2024.07.010","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"43-44"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medicina ClinicaPub Date : 2025-01-10Epub Date: 2024-10-29DOI: 10.1016/j.medcli.2024.08.004
Adrián Peláez, Joan B Soriano, María Rodrigo-García, José L Peñalvo, Julio Ancochea, Esteve Fernández
{"title":"Trends in mortality in Spain, with a special focus on respiratory-related conditions in the midst of the COVID-19 pandemic.","authors":"Adrián Peláez, Joan B Soriano, María Rodrigo-García, José L Peñalvo, Julio Ancochea, Esteve Fernández","doi":"10.1016/j.medcli.2024.08.004","DOIUrl":"10.1016/j.medcli.2024.08.004","url":null,"abstract":"<p><strong>Background and objective: </strong>The COVID-19 pandemic significantly increased the global burden of respiratory morbidity and mortality. In Spain, 2020 saw a 68.5% surge in deaths from respiratory diseases compared to 2019, largely due to COVID-19. This study aims to describe respiratory disease mortality in Spain from 2019 to 2022, focusing on the intersection of COVID-19, pre-existing respiratory conditions, and specific health determinants.</p><p><strong>Materials and methods: </strong>We analyzed mortality data from the Spanish National Institute of Statistics (INE), covering 102 causes of death, including tuberculosis, COVID-19, and lung cancer as respiratory-related conditions. The analysis considered absolute death counts and proportions by sex, age, and region, along with percentage changes in proportional mortality. Logistic regression models were used to identify factors potentially associated with COVID-19 and respiratory-specific mortality.</p><p><strong>Results: </strong>In 2022, Spain reported 98,128 deaths from respiratory diseases, accounting for 21.1% of all deaths and ranking as the second leading cause of death after cardiovascular diseases. Although deaths due to COVID-19 decreased in 2021 and 2022, there was a notable rise in other respiratory causes, indicating a lasting post-pandemic impact. Factors linked to higher mortality included male gender, older age, being divorced, and residing in urban areas, with significant regional variability.</p><p><strong>Conclusions: </strong>Despite overall mortality returning to pre-pandemic levels, this study highlights a significant increase in respiratory disease deaths in Spain in 2022 compared to 2019.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":"1-9"},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}