Medicina Clinica最新文献

{"title":"Agradecimientos","authors":"","doi":"10.1016/S0025-7753(25)00320-3","DOIUrl":"10.1016/S0025-7753(25)00320-3","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"164 12","pages":"Article 107092"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144330035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Livedo racemosa secundaria a embolización de la arteria genicular en una paciente con artrosis de rodilla","authors":"Lula María Nieto Benito, Pablo Fonda Pascual, Loreto Carrasco Santos","doi":"10.1016/j.medcli.2025.107071","DOIUrl":"10.1016/j.medcli.2025.107071","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107071"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major adverse cardiovascular events among patients with type 2 diabetes mellitus: A prospective study","authors":"David Martín-Enguix ,&nbsp;Juan Carlos Aguirre Rodríguez ,&nbsp;Abraham Hidalgo Rodríguez ,&nbsp;María Guisasola Cárdenas ,&nbsp;María Sánchez Cambronero ,&nbsp;María Nieves Generoso Torres ,&nbsp;Manuel Joaquín Castillo ,&nbsp;Francisco José Amaro-Gahete","doi":"10.1016/j.medcli.2025.107028","DOIUrl":"10.1016/j.medcli.2025.107028","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Large-scale studies (UKPDS and CALIBER) reported annual major adverse cardiovascular events (MACE) rates of 2.5–2.6% occurrence in patients with type 2 diabetes mellitus (T2D). However, data for different geographical locations in Spain are unknown. The aim of this study was to investigate the most common causes of MACE and the factors that contribute to its occurrence in patients with DM2 living in southern Spain.</div></div><div><h3>Methods</h3><div>In this cohort study, 297 patients with T2D were monitored over 49 months to assess the occurrence of MACE (i.e., stroke, myocardial infarction, and/or cardiovascular death). Sociodemographic and clinical data (including cardiovascular disease risk factors and initial treatments) were collected to examine their impact on the incidence of MACE.</div></div><div><h3>Results</h3><div>The mean age of the cohort was 67.7 years, with a male predominance (53.3%) and an average T2D duration of 8.8 years. Over the 4-year follow-up, 10.7% of patients experienced a MACE, with myocardial infarction and cardiovascular death being the most prevalent events (both 38.7%). In multivariate analysis, each additional year of T2D evolution was associated with a 15% increased risk of MACE (HR<!--> <!-->=<!--> <!-->1.150 [1.006–1.314], <em>p</em> <!-->=<!--> <!-->0.041), while each unit increase in estimated glomerular filtration rate (eGFR) was linked to a 3.3% risk reduction (HR<!--> <!-->=<!--> <!-->0.967 [0.938–0.997], <em>p</em> <!-->=<!--> <!-->0.033).</div></div><div><h3>Conclusion</h3><div>Myocardial infarction and cardiovascular death were the leading causes of MACE in T2D patients over a 4-year follow-up. Longer T2D duration and lower eGFR were the most significant risk factors. These findings underscore the need of closer monitoring and intensive treatment in patients with long-standing T2D and/or impaired renal function.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107028"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalloped pupil in a patient with hereditary amyloidosis transthyretin","authors":"Alex de Novais Batista,&nbsp;João Eudes Magalhães","doi":"10.1016/j.medcli.2025.107069","DOIUrl":"10.1016/j.medcli.2025.107069","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107069"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fascitis eosinofílica","authors":"Iago Pinal-Fernández ,&nbsp;José César Milisenda ,&nbsp;Albert Selva-O’Callaghan","doi":"10.1016/j.medcli.2025.107066","DOIUrl":"10.1016/j.medcli.2025.107066","url":null,"abstract":"<div><div>Eosinophilic fasciitis is a rare scleroderma-like syndrome of unknown cause. It is characterized by painful induration and progressive thickening of the muscular fascia and subcutaneous tissue of the limbs and trunk. The most common laboratory findings include peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate. The diagnosis is confirmed through a full-thickness wedge biopsy of the affected skin, revealing inflammation and thickening of the deep fascia.</div><div>The differential diagnosis includes scleroderma, morphea, myofasciitis in graft-versus-host disease, and epidemic fasciitis syndromes caused by toxins, such as eosinophilia-myalgia syndrome and toxic oil syndrome. Although the diagnosis is based on clinical, laboratory, and histological findings, no universal diagnostic criteria exist. Glucocorticoids are the standard treatment, although some patients may improve spontaneously.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107066"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glufosinate-ammonium poisoning: A clinical case","authors":"Junwei Luo,&nbsp;Lingjun Kong,&nbsp;Yuanyuan Kuang","doi":"10.1016/j.medcli.2025.107072","DOIUrl":"10.1016/j.medcli.2025.107072","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107072"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tiña genital","authors":"Elisabeth Gómez Moyano ,&nbsp;Fátima Moreno Suárez ,&nbsp;Leandro Martínez Pilar","doi":"10.1016/j.medcli.2025.107064","DOIUrl":"10.1016/j.medcli.2025.107064","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107064"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of thalidomide in the treatment of classic (ulcerative) idiopathic pyoderma gangrenosum. A retrospective study of 80 patients","authors":"Andrés Tirado-Sánchez","doi":"10.1016/j.medcli.2025.107070","DOIUrl":"10.1016/j.medcli.2025.107070","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107070"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fenómeno isotópico de Wolf en un paciente con linfoma linfoblástico de células T","authors":"Vanesa Garrigasait Vilaseca ,&nbsp;Eduardo Subiela Perez ,&nbsp;Ignasi Espadaler Fabrego ,&nbsp;Isabel Lasheras Peral ,&nbsp;Ana Muntañola Prat","doi":"10.1016/j.medcli.2025.107073","DOIUrl":"10.1016/j.medcli.2025.107073","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 5","pages":"Article 107073"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnóstico de penfigoide anti-p200 sin inmunoblot: utilidad de la inmunohistoquímica para colágeno IV","authors":"Marta Cebolla-Verdugo ,&nbsp;David Moyano-Bueno ,&nbsp;Ricardo Ruiz-Villaverde","doi":"10.1016/j.medcli.2025.107068","DOIUrl":"10.1016/j.medcli.2025.107068","url":null,"abstract":"","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 3","pages":"Article 107068"},"PeriodicalIF":2.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}