Medicina Clinica最新文献_第3页

Estrategias terapéuticas en las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilo 使用中性粒细胞抗细胞质抗体治疗血管炎的策略

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-07-16 DOI: 10.1016/j.medcli.2025.107038

Beatriz Sánchez-Álamo

引用次数: 0

Impact of vericiguat on functional class and hospitalizations in patients with heart failure and reduced ejection fraction: A retrospective cohort study vericiguat对心力衰竭和射血分数降低患者功能分级和住院的影响：一项回顾性队列研究

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-07-14 DOI: 10.1016/j.medcli.2025.107067

José María Medina-Gil , Acerina Rodríguez-Reyes , Efrén Martínez-Quintana

引用次数: 0

Sialoadenitis aguda por administración de contraste yodado 使用碘造影剂引起的急性唾液腺炎

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-07-03 DOI: 10.1016/j.medcli.2025.107020

Anna Moreno Cosialls , Maria Huguet Mas

引用次数: 0

Efectos adversos y otros aspectos de los fármacos con efecto incretínico 增殖药物的副作用和其他方面

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-07-02 DOI: 10.1016/j.medcli.2025.107041

Maria D. Ballesteros-Pomar , Irene Bretón

引用次数: 0

Metabolic profiles of Turner syndrome: A real-world cohort study 特纳综合征的代谢概况：一项真实世界的队列研究

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-25 DOI: 10.1016/j.medcli.2025.107061

Zhibo Zhou , Shan Xiao , Xiaoyuan Guo , Yiling He , Shi Chen , Hongbo Yang , Hui Pan , Huijuan Zhu

{"title":"Metabolic profiles of Turner syndrome: A real-world cohort study","authors":"Zhibo Zhou , Shan Xiao , Xiaoyuan Guo , Yiling He , Shi Chen , Hongbo Yang , Hui Pan , Huijuan Zhu","doi":"10.1016/j.medcli.2025.107061","DOIUrl":"10.1016/j.medcli.2025.107061","url":null,"abstract":"<div><h3>Background and objective</h3><div>Turner syndrome (TS), primarily characterized by premature ovarian insufficiency, is a disease resulting from a complete or partial absence of the second X chromosome. This study aims to describe the prevalence of metabolic comorbidities in TS patients of different ages and karyotypes.</div></div><div><h3>Methods</h3><div>The medical history, diagnosis, physical examination, laboratory examination and imaging examination data of 145 TS patients were obtained from the medical files.</div></div><div><h3>Results</h3><div>(1) In total, 4.1% of the TS patients in this cohort were diagnosed with hypertension, and elderly patients had higher blood pressure. (2) 6.9% of patients were diagnosed with diabetes, and monosomic TS had a lower TyG index. (3) The prevalence of dyslipidemia and fatty liver was 20.0% and 16.7% respectively. TS patients treated with recombinant human growth hormone (rhGH) had significantly higher LDL-C and Apo-A1 levels. (4) The prevalence of hyperuricemia was 27.6%, and higher uric acid levels were observed in young patients and those receiving rhGH treatment. A total of 17.2% of patients were diagnosed with liver dysfunction. (5) The prevalence of low bone mass, which was higher in elderly patients and those without rhGH treatment, was 53.8% in TS patients older than 19 years.</div></div><div><h3>Conclusions</h3><div>TS patients have a higher prevalence of metabolic comorbidities, including dyslipidemia, fatty liver, hyperuricemia, liver dysfunction and low bone mass. RhGH treatment in childhood had some positive effects on glucose, lipid and bone metabolism in young adulthood. Therefore, additional attention should be given to metabolic comorbidities in TS patients at high risk.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107061"},"PeriodicalIF":2.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144472192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of relapsed multiple myeloma presenting as testicular plasmacytoma with stable bone marrow disease 多发性骨髓瘤复发表现为睾丸浆细胞瘤伴稳定骨髓疾病的诊断

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-25 DOI: 10.1016/j.medcli.2025.107049

Rita González-Resina , Robert R. Rodríguez-Carpio , Ana C. Godoy-Molias

引用次数: 0

Los análogos de la PTH/PTHrP como tratamiento osteoanabólico de los pacientes con osteoporosis PTH/PTHrP类似物作为骨质疏松症患者的骨合成代谢治疗

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-25 DOI: 10.1016/j.medcli.2025.107076

Enrique Casado , Guillermo Martínez-Díaz-Guerra , José Ramon Caeiro

引用次数: 0

Donación renal: criterios de aceptación y su influencia a los 5 y 10 años post donación 肾脏捐献：接受标准及其对捐献后5年和10年的影响

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-25 DOI: 10.1016/j.medcli.2025.107062

Silvana Alejandra Nuñez , Pehuén Fernández , Walter Douthat , Javier de Arteaga , Emanuel José Saad , Jorge de la Fuente , Carlos Chiurchiu

{"title":"Donación renal: criterios de aceptación y su influencia a los 5 y 10 años post donación","authors":"Silvana Alejandra Nuñez , Pehuén Fernández , Walter Douthat , Javier de Arteaga , Emanuel José Saad , Jorge de la Fuente , Carlos Chiurchiu","doi":"10.1016/j.medcli.2025.107062","DOIUrl":"10.1016/j.medcli.2025.107062","url":null,"abstract":"<div><h3>Introduction</h3><div>Acceptance criteria for kidney donors (KDs) have become more flexible over time, raising questions about their long-term consequences. The objective of this study was to evaluate changes in the baseline characteristics of accepted KDs and to analyze their evolution after donation.</div></div><div><h3>Methods</h3><div>A cohort study was conducted that included all KDs from our institution from 2010 to 2017. Baseline characteristics were compared by period and follow-up was carried out up to 10years after donation.</div></div><div><h3>Results</h3><div>169 KDs aged 45.6±12.2years were included, mostly women (63.9%). The main comorbidity they presented was obesity (29.6%) and controlled arterial hypertension (10.7%). KDs showed significant differences in estimated glomerular filtration rate (eGFR) with lower values in the last study period (<em>P</em>        =.033) and pre-donation eGFR (HRa=0,97; 95%CI: 0.95-0,99; <em>P</em>     <!-->years of post-donation follow-up, so it seems to be a safe procedure in our environment in the long term.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 4","pages":"Article 107062"},"PeriodicalIF":2.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144472193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enterocolic lymphocytic phlebitis: Clinical insights from a literature review 肠结肠淋巴细胞性静脉炎：来自文献回顾的临床见解

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-23 DOI: 10.1016/j.medcli.2025.107065

Ying Zhao , Xiaoying Zhang , Yongsheng Li , Jinhua He , Zeping Han

{"title":"Enterocolic lymphocytic phlebitis: Clinical insights from a literature review","authors":"Ying Zhao , Xiaoying Zhang , Yongsheng Li , Jinhua He , Zeping Han","doi":"10.1016/j.medcli.2025.107065","DOIUrl":"10.1016/j.medcli.2025.107065","url":null,"abstract":"<div><h3>Objective</h3><div>Enterocolic lymphocytic phlebitis (ELP) is a rare venous-specific gastrointestinal inflammation with challenging preoperative diagnosis. We aimed to characterize its clinicopathological spectrum.</div></div><div><h3>Patients and methods</h3><div>This narrative review synthesizes evidence from 85 published cases (9–81 years) from 50 articles to characterize ELP's clinicopathological features and diagnostic pitfalls, along with its differentiation from other vasculitides, such as Behcet's disease, systemic lupus erythematosus, mesenteric inflammatory veno-occlusive disease, idiopathic myointimal hyperplasia of the mesenteric veins and IgG4-related diseases.</div></div><div><h3>Results</h3><div>ELP has a wide range of clinical and histological presentations, it predominantly affects the right colon/small bowel, mimicking acute abdomen. Diagnosis relies on postoperative histopathology showing venular lymphocytic infiltration.</div></div><div><h3>Conclusion</h3><div>ELP represents a underdiagnosed clinicopatologic entity, a diagnosis of ELP is predominantly made after histological resection.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"165 5","pages":"Article 107065"},"PeriodicalIF":2.6,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid remission of SAPHO syndrome with secukinumab 使用secukinumab快速缓解SAPHO综合征

IF 2.6 4区医学

Medicina Clinica Pub Date : 2025-06-23 DOI: 10.1016/j.medcli.2025.107050

Guangliang Wei, Huidong Chen, Jie Chen

引用次数: 0