Medicina Clinica最新文献_第7页

A comprehensive approach to end-of-life care. Medical-legal, ethical, social, psychological and care aspects. 临终关怀的综合方法。医疗、法律、伦理、社会、心理和护理等方面。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-19 DOI: 10.1016/j.medcli.2024.10.001

Josep Arimany-Manso, Francesc Torralba, Ana Isabel Lima, María Die Trill

引用次数: 0

Increasing prevalence of psoriasis in Spain: A population-based study (2018-2022). 西班牙银屑病发病率不断上升：一项基于人口的研究（2018-2022 年）。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-18 DOI: 10.1016/j.medcli.2024.08.019

Lucía Cayuela, José-Juan Pereyra-Rodríguez, Juan-Carlos Hernández-Rodríguez, Lourdes Rodríguez Fernandez-Freire, Aurelio Cayuela

{"title":"Increasing prevalence of psoriasis in Spain: A population-based study (2018-2022).","authors":"Lucía Cayuela, José-Juan Pereyra-Rodríguez, Juan-Carlos Hernández-Rodríguez, Lourdes Rodríguez Fernandez-Freire, Aurelio Cayuela","doi":"10.1016/j.medcli.2024.08.019","DOIUrl":"https://doi.org/10.1016/j.medcli.2024.08.019","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the prevalence of psoriasis in Spain from 2018 to 2022 and analyze trends by sex and age groups.</p><p><strong>Methods: </strong>We used the Primary Care Clinical Database (BDCAP) to identify individuals coded with psoriasis (S91) during the study period. Population data for calculating rates was obtained from the Primary Care Information System (SIAP). Crude, age- and sex-specific, and standardized prevalence rates were calculated. Joinpoint analysis assessed annual percentage change (APC) in prevalence.</p><p><strong>Results: </strong>The estimated psoriasis prevalence in Spain in 2022 was 1.9%. Psoriasis prevalence increased substantially by 43.3% (from 692,317 to 991,832 cases) over the study period. We observed a clear increase in both crude and standardized prevalence rates for men (7.2% annual increase) and women (8.3% annual increase) throughout the study period. Men consistently had slightly higher prevalence rates than women. Prevalence increased with age, reaching a peak in the 70-74 age group for men and 60-64 for women, before declining in older age groups.</p><p><strong>Conclusions: </strong>This study revealed a concerning increase in psoriasis prevalence in Spain, independent of population aging. Increased disease awareness, improved diagnostics, and greater treatment seeking behavior are potential explanations. Further research is needed to explore the underlying causes of this rise and inform public health interventions.</p>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of genetics in the diagnosis of sudden cardiac death. Interest of forensic and legal medicine. 遗传学在诊断心脏性猝死方面的挑战。法医和法律医学的兴趣。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-18 DOI: 10.1016/j.medcli.2024.10.002

Alejandro Blanco-Verea, Ángel Carracedo, María Brion

引用次数: 0

¿Se tiene en cuenta la ingesta de etanol? 我们是否考虑过乙醇的消耗量？

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-15 DOI: 10.1016/j.medcli.2024.04.030

Javier Velasco Montes , Silvia González Díez , Elena Rivas Cilleros

引用次数: 0

Aspectos medicolegales en las enfermedades infecciosas 传染病的医疗法律问题。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-15 DOI: 10.1016/j.medcli.2024.06.003

Robert Güerri-Fernández , Josep Benet , César Vargas

{"title":"Aspectos medicolegales en las enfermedades infecciosas","authors":"Robert Güerri-Fernández , Josep Benet , César Vargas","doi":"10.1016/j.medcli.2024.06.003","DOIUrl":"10.1016/j.medcli.2024.06.003","url":null,"abstract":"<div><div>This article reviews the medico-legal aspects associated with infectious diseases, highlighting their complexity and the challenges they pose. Infectious diseases cause not only an increase in morbidity and mortality in the healthcare setting but also involve complex legal issues. Healthcare-Associated Infections (HAIs) represent a growing risk with the increase in invasive procedures and can lead to patient complications and legal claims against healthcare professionals and institutions. The consequences of medical malpractice in this context are discussed, such as diagnostic delays, inappropriate use of treatments, and lack of adequate testing, which can have serious sequelae or even result in the patient's death.</div><div>The review focuses on highlighting the importance of prevention, considering that healthcare-associated infections can be difficult to avoid, posing complex legal challenges.</div><div>It concludes that managing infectious diseases and their legal consequences requires careful consideration of clinical practice guidelines, prevention and control strategies, and effective communication with patients. An integrated and evidence-based approach is advocated to address these challenges, emphasizing continuous education, the use of advanced diagnostic technologies, and interdisciplinary collaboration.</div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"163 9","pages":"Pages e98-e102"},"PeriodicalIF":2.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parkinsonism in liver diseases or dysfunction 肝脏疾病或功能障碍导致的帕金森症。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-15 DOI: 10.1016/j.medcli.2024.04.022

Sichen Li, Yuxia Zhua, Xi Liu

{"title":"Parkinsonism in liver diseases or dysfunction","authors":"Sichen Li, Yuxia Zhua, Xi Liu","doi":"10.1016/j.medcli.2024.04.022","DOIUrl":"10.1016/j.medcli.2024.04.022","url":null,"abstract":"<div><div>Parkinsonism in liver diseases or dysfunction, mainly including neurological manifestations in hereditary liver diseases and neurological complications of advanced liver diseases, occur in isolation or in combination with other movement disorders, and progress along disease course. Prominent akinetic-rigidity syndrome, various onset and progression, poor levodopa<span> response and metabolism abnormalities reflected by serum biomarkers and neuroimaging, make this atypical parkinsonism recognizable and notable in clinical practice. Different susceptibility of brain areas, especially in basal ganglia, to manganese, iron, copper, ammonia overload, together with subsequent oxidative stress, neurotransmitter alterations, disturbed glia-neuron homeostasis and eventually neurotoxicity, contribute to parkinsonism under the circumstances of insufficient liver clearance ability. These mechanisms are interrelated and may interact collectively, adding to the complexity of clinical manifestations and treatment responses. This review summarizes shared clinical features of parkinsonism in liver diseases or dysfunction, depicts their underlying mechanisms and suggests practical flowchart for differential diagnosis.</span></div></div>","PeriodicalId":18578,"journal":{"name":"Medicina Clinica","volume":"163 9","pages":"Pages 461-468"},"PeriodicalIF":2.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hipertensión arterial pulmonar asociada a lupus eritematoso sistémico: descripción de una serie de casos 与系统性红斑狼疮相关的肺动脉高压：一个病例系列。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-15 DOI: 10.1016/j.medcli.2024.05.009

Rossio Gardenia Ortuño Lobo, Marina Garcia Carrasco, Gustavo Medina

引用次数: 0

Mielitis por Listeria en adulto inmunocompetente con respuesta favorable a gentamicina intratecal 免疫功能正常的成年患者患李斯特菌脊髓炎，但对鞘内庆大霉素反应良好。

IF 2.6 4区医学

Medicina Clinica Pub Date : 2024-11-15 DOI: 10.1016/j.medcli.2024.05.006

Eva González Martínez, Maite Misis del Campo, Fidel Nuñez Marín

引用次数: 0

Genetic analysis of a family with hereditary hemorrhagic telangiectasia caused by a novel frameshift deletion mutation of the endoglin (ENG) gene 一个遗传性出血性毛细血管扩张症家族的基因分析，该家族由内切酶蛋白（ENG）基因的新型缺失突变引起。