Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-06-26DOI: 10.4103/mgr.MEDGASRES-D-23-00056
Sajid Farooq, Allan Bereczki, Muhammad Habib, Isolda Costa, Olavo Cardozo
{"title":"High-performance plasmonics nanostructures in gas sensing: a comprehensive review.","authors":"Sajid Farooq, Allan Bereczki, Muhammad Habib, Isolda Costa, Olavo Cardozo","doi":"10.4103/mgr.MEDGASRES-D-23-00056","DOIUrl":"10.4103/mgr.MEDGASRES-D-23-00056","url":null,"abstract":"<p><p>Plasmonic nanostructures have emerged as indispensable components in the construction of high-performance gas sensors, playing a pivotal role across diverse applications, including industrial safety, medical diagnostics, and environmental monitoring. This review paper critically examines seminal research that underscores the remarkable efficacy of plasmonic materials in achieving superior attributes such as heightened sensitivity, selectivity, and rapid response times in gas detection. Offering a synthesis of pivotal studies, this review aims to furnish a comprehensive discourse on the contemporary advancements within the burgeoning domain of plasmonic gas sensing. The featured investigations meticulously scrutinize various plasmonic structures and their applications in detecting gases like carbon monoxide, carbon dioxide, hydrogen and nitrogen dioxide. The discussed frameworks encompass cutting-edge approaches, spanning ideal absorbers, surface plasmon resonance sensors, and nanostructured materials, thereby elucidating the diverse strategies employed for advancing plasmonic gas sensing technologies.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"1-9"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-10-02DOI: 10.4103/mgr.MEDGASRES-D-24-00005
Xu Zhang, Shi-Jun Wang, Si-Cen Wan, Xiang Li, Gang Chen
{"title":"Ozone: complicated effects in central nervous system diseases.","authors":"Xu Zhang, Shi-Jun Wang, Si-Cen Wan, Xiang Li, Gang Chen","doi":"10.4103/mgr.MEDGASRES-D-24-00005","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00005","url":null,"abstract":"<p><p>Oxidative stress is closely related to various diseases. Ozone can produce redox reactions through its unique response. As a source of the oxidative stress response, the strong oxidizing nature of ozone can cause severe damage to the body. On the other hand, low ozone concentrations can activate various mechanisms to combat oxidative stress and achieve therapeutic effects. Some animal experiments and clinical studies have revealed the potential medical value of ozone, indicating that ozone is not just a toxic gas. By reviewing the mechanism of ozone and its therapeutic value in treating central nervous system diseases (especially ischemic stroke and Alzheimer's disease) and the toxic effects of ozone, we find that ozone inhalation and a lack of antioxidants or excessive exposure lead to harmful impacts. However, with adequate antioxidants, ozone can transmit oxidative stress signals, reduce inflammation, reduce amyloid β peptide levels, and improve tissue oxygenation. Similar mechanisms to those of possible new drugs for treating ischemic stroke and Alzheimer's disease indicate the potential of ozone. Nevertheless, limited research has restricted the application of ozone. More studies are needed to reveal the exact dose-effect relationship and healing effect of ozone.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"44-57"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical Gas ResearchPub Date : 2025-03-01Epub Date: 2024-10-02DOI: 10.4103/mgr.MEDGASRES-D-23-00003
Hao Wu, Sheng Wang, Fei-Biao Dai, Chao-Liang Tang
{"title":"Research progress in the clinical application of inhaled anesthetic sevoflurane.","authors":"Hao Wu, Sheng Wang, Fei-Biao Dai, Chao-Liang Tang","doi":"10.4103/mgr.MEDGASRES-D-23-00003","DOIUrl":"10.4103/mgr.MEDGASRES-D-23-00003","url":null,"abstract":"<p><p>Sevoflurane has been widely used in clinical anesthesia as an inhalation anesthetic. With the development of medicine, there have been several new applications in recent years, such as daytime surgery, labor analgesia, and combined nerve block for some surgeries. Moreover, as research progresses, it has been found that it not only has potential organ protection effects but can also be used to treat severe asthma and relieve the tracheal spasm state. In addition, local administration can effectively treat vascular ulcers. We briefly review the organ protective effect of sevoflurane, its application in dental treatment, asthma treatment, vascular ulcer treatment and some new progress in clinical application.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"85-92"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The overlooked benefits of hydrogen-producing bacteria.","authors":"Yusuke Ichikawa, Haru Yamamoto, Shin-Ichi Hirano, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh","doi":"10.4103/2045-9912.344977","DOIUrl":"https://doi.org/10.4103/2045-9912.344977","url":null,"abstract":"<p><p>Intestinal bacteria can be classified into \"beneficial bacteria\" and \"harmful bacteria.\" However, it is difficult to explain the mechanisms that make \"beneficial bacteria\" truly beneficial to human health. This issue can be addressed by focusing on hydrogen-producing bacteria in the intestines. Although it is widely known that molecular hydrogen can react with hydroxyl radicals, generated in the mitochondria, to protect cells from oxidative stress, the beneficial effects of hydrogen are not fully pervasive because it is not generally thought to be metabolized in vivo. In recent years, it has become clear that there is a close relationship between the amount of hydrogen produced by intestinal bacteria and various diseases, and this report discusses this relationship.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"108-111"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/25/MGR-13-108.PMC9979208.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9076376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael Torres-Rosas, María Eugenia Marcela Castro-Gutiérrez, Luis Angel Flores-Mejía, Eduardo Ulises Torres-Rosas, Roberto Miguel Nieto-García, Liliana Argueta-Figueroa
{"title":"Ozone for the treatment of temporomandibular joint disorders: a systematic review and meta-analysis.","authors":"Rafael Torres-Rosas, María Eugenia Marcela Castro-Gutiérrez, Luis Angel Flores-Mejía, Eduardo Ulises Torres-Rosas, Roberto Miguel Nieto-García, Liliana Argueta-Figueroa","doi":"10.4103/2045-9912.345174","DOIUrl":"https://doi.org/10.4103/2045-9912.345174","url":null,"abstract":"<p><p>Temporomandibular joint disorders (TMD) generate pain and difficulties for mouth opening affecting the patients' quality of life. Ozone is an emerging therapy that has been proposed as a potential treatment, due to that, the evidence about its efficacy should be reviewed. Therefore, this work aimed to conduct a comprehensive systematic review to address the efficacy of ozone therapy for the treatment of pain and limited mouth opening in patients with TMD. The design of the included studies was clinical trials and observational studies, whereas, a series of cases, in vivo, and in vitro studies were excluded. The search was performed in PubMed, ClinicalTrials, Web of Science, and Scopus. Gray literature was searched at Google Scholar. Relevant data of all included studies were recorded. The risk of bias (using RoB 2) and the quality (using Grading of Recommendations Assessment, Development, and Evaluation) assessments were carried out. Meta-analyses using random-effects models of pain and maximal mouth opening data were performed. This review included 8 studies with 404 participants suffering limited function and pain related to TMD. At the overall bias of the studies, 25% exhibited some concerns and 75% had high risk; and the quality of the studies was low. The analysis of the included studies suggests that ozone therapy can diminish pain and improve the maximal mouth opening in TMD patients. However, there is no conclusive evidence of ozone therapy as a superior treatment for TMD compared with occlusal splint and pharmacotherapy.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"149-154"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/d2/MGR-13-149.PMC9979202.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pavitra Patil, Pavan Vithal Dhulkhed, Vithal K Dhulkhed
{"title":"Isobaric forms of ropivacaine <i>vs</i>. bupivacaine in lower abdominal surgeries: a hospital-based, prospective, comparative study.","authors":"Pavitra Patil, Pavan Vithal Dhulkhed, Vithal K Dhulkhed","doi":"10.4103/2045-9912.359678","DOIUrl":"https://doi.org/10.4103/2045-9912.359678","url":null,"abstract":"<p><p>We aimed to assess whether ropivacaine (0.75%; 22.5 mg) can replace bupivacaine (0.5%; 15 mg) as a better intrathecal anesthetic in lower abdominal surgery. In this hospital-based, single-blind, randomized, prospective, comparative study, 100 patients of either sex, aged between 18 and 70 years, weighing 40-80 kg, with American Society of Anesthesiologists physical status 1 and 2, and undergoing lower abdominal surgery were randomly allocated into two groups to receive intrathecal isobaric bupivacaine 0.5% 3 mL (15 mg) or ropivacaine 0.75% 3 mL (22.5 mg). In the intraoperative period, the onset, efficacy, duration, and regression of sensory and motor blockade and the quality of anesthesia and hemodynamic effects were observed at regular intervals. The ropivacaine and bupivacaine groups were comparable for demographic parameters. The duration of onset of sensory and motor blocks was significantly shorter in the bupivacaine group (P < 0.01). In the ropivacaine group, a faster recovery from sensory block (P = 0.02) and higher segmental height [thoracic (T)10 and T8] were achieved (P < 0.01). Bradycardia and hypotension were insignificant in the ropivacaine group (P > 0.05). Isobaric ropivacaine is a better spinal anesthetic in lower abdominal surgeries as it provides faster recovery from sensory block and a higher level of segmental sensory block with fewer side-effects.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"123-127"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/5d/MGR-13-123.PMC9979211.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A randomized controlled study to compare analgesic efficacy of sublingual buprenorphine and intravenous tramadol in patients undergoing mastectomy.","authors":"Krishna Sumanth Dokku, Abhijit Sukumaran Nair, Srinivasa Shyam Prasad Mantha, Vibhavari Milind Naik, Mohammed Salman Saifuddin, Basanth Kumar Rayani","doi":"10.4103/2045-9912.345170","DOIUrl":"10.4103/2045-9912.345170","url":null,"abstract":"<p><p>Sublingual (SL) buprenorphine is approved for managing acute postoperative pain, characterized by easy administration, good pain relief and good patient compliance. We hypothesized that SL buprenorphine would be a better perioperative analgesic compared to intravenous (IV) opioids like tramadol in patients undergoing mastectomy surgery for breast cancer. After institutional ethics committee approval, we randomized 60 patients with breast cancer into 2 groups. In buprenorphine group, patients received 200 μg of SL buprenorphine thrice daily and in tramadol group patients received 100 mg of IV tramadol thrice daily. The analgesic efficacy of SL buprenorphine was comparable to that of IV tramadol. Visual Analogue Scale scores had no significant difference between the two groups at various time frames (0, 1, 3, 6, 12, 18 and 24 hours) at rest and movement except at 0 and 3 hours during movement when the score was lower in the tramadol group than the buprenorphine group. Four patients in the buprenorphine group received rescue analgesic (IV morphine 3 mg). Analgesic efficacy of SL buprenorphine appears comparable to IV tramadol for managing postoperative pain after mastectomy. SL buprenorphine can be administered sublingually, which is an advantage.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"118-122"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/c2/MGR-13-118.PMC9979200.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Martiele Engelmann, Andressa Bueno, Nathalia Viana Barbosa, Carolina Machado, Diego Correa, Juliana Felipetto Cargnelutti, Cinthia Melazzo de Andrade
{"title":"Effectiveness of ozonized saline solution in the treatment of <i>Proteus</i> spp. bacterial cystitis.","authors":"Ana Martiele Engelmann, Andressa Bueno, Nathalia Viana Barbosa, Carolina Machado, Diego Correa, Juliana Felipetto Cargnelutti, Cinthia Melazzo de Andrade","doi":"10.4103/2045-9912.350861","DOIUrl":"https://doi.org/10.4103/2045-9912.350861","url":null,"abstract":"<p><p>Bacterial cystitis is a common clinical problem among cats and dogs and is one of the main reasons for the administration of antimicrobials. This can cause serious damage to public and animal health, as this practice facilitates the selection of bacteria that are multidrug-resistant to antibiotics. In this context, it is urgent to understand and validate therapeutic modalities that complement antimicrobial treatment in cystitis cases. Ozone therapy has been proposed by scientists owing to the various mechanisms of action in a range of pathologies, both in human and animal medicine. This paper describes the bactericidal action of two different protocols of bladder irrigation with ozonized saline solution (59 μg/mL) in a paraplegic canine with recurrent bacterial cystitis caused by Proteus spp. In the first protocol, the bladder instillations were applied once a day for three consecutive days while in the second, successive lavages were performed throughout the day until a significant reduction in the presence of bacteria in the urine sediment. In this study, we were able to demonstrate that repeated bladder instillation within 24 hours was the most effective treatment for Proteus compared to a single instillation on successive days.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"155-158"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/1c/MGR-13-155.PMC9979206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amit Rai, Krithika Ramamoorthy, Sachin Kulkarni, Sameer Taneja
{"title":"A major leak from the condenser assembly of the anesthesia workstation.","authors":"Amit Rai, Krithika Ramamoorthy, Sachin Kulkarni, Sameer Taneja","doi":"10.4103/2045-9912.345173","DOIUrl":"https://doi.org/10.4103/2045-9912.345173","url":null,"abstract":"Dear Editor, From a simple pneumatic device of the early 20th century, the anesthesia machine has evolved to incorporate various mechanical, electrical and electronic components to be more appropriately called anesthesia workstation.1 Despite advanced technology, a remote but life-threatening possibility of intraoperative machine malfunction exists. The leakage in the anesthesia circuit may result in hypoventilation, hypoxia, awareness, pollution of operating room and ventilatory failure even leading to death.2 Various causes of leaks in the breathing system have been reported in the literature that includes failure of an adjustable pressure limiting valve to close, mis-installation of a canister,3 weak connections in between different parts of the breathing circuit. We reported a case of gas leak from an unconventional site in the Datex Ohmeda Aespire View (GE Healthcare Pvt. Ltd. (India), Bangalore, India) workstation after anesthesia machine checks. As a routine, the complete pre-use anesthesia machine check was performed through the electronic self-check. A complete pre-use check of the machine included cylinders, pipelines, low-pressure system, vaporizers, breathing circuits, monitors and integrated ventilator. The circle system was also checked for any leaks and the ventilator systems were checked by setting the oxygen flow meter at minimum flows. However, after preliminary checks, soda lime in the carbon dioxide (CO2) absorber canister was changed. The canister was then reattached firmly. The water trap was also drained at this time. The patient was induced with propofol but bag mask ventilation was not adequate. There was a chest rise along with an end tidal CO2 trace but the reservoir bag was not filled adequately at a usual flow of 5 L/min. An oropharyngeal airway was inserted, and the flow increased to 10 L/min and the bag was filled better. The trachea was intubated with an 8.5 mm internal diameter cuffed endotracheal polyvinyl chloride tube using succinylcholine. However, the bag still required higher flows to fill up and when turned to the ventilation mode, the bellows required more than 8 L/min to fill up. We checked all the connections in the external circuit but found no loose connections or leaks. However, there was a large audible leak heard from the soda lime canister assembly. The CO2 absorber canister was removed and put back again to ensure that it is secured appropriately and locked. However, the audible leak still persisted. We decided to go ahead with the surgery as it was an emergency and ventilate the patient manually using Bains circuit. After the surgery got over, a detailed inspection of the CO2 canister assembly was done, and the leak seemed to originate from the EZchange and condenser part of the machine (Figure 1). Further evaluation revealed no issue in the EZchange part. The drain button of the condenser, however, was stuck in a semiopen position due to a soda lime granule trapped under the flap valve, leading ","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"13 3","pages":"159-160"},"PeriodicalIF":2.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/12/MGR-13-159.PMC9979204.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9076378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}