Medical Gas Research最新文献

{"title":"Biological gases, oxidative stress, artificial intelligence, and machine learning for neurodegeneration and metabolic disorders.","authors":"Kenneth Maiese","doi":"10.4103/mgr.MEDGASRES-D-24-00059","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00059","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"145-147"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon monoxide inhalation as a potential aid to enhance aerobic endurance.","authors":"Bezuglov Eduard, Achkasov Evgeniy, Kapralova Elizaveta, Rudiakova Elizaveta, Shurygin Vladimir, Malyakin Georgiy, Sadkovaya Olga, Talibov Oleg, Baymeeva Natalia, Michail Vartapetov, Morgans Ryland","doi":"10.4103/mgr.MEDGASRES-D-24-00021","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00021","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"117-119"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatigue disappearance in hemodialysis patients by dual approach with hydrogen gas inhalation and hydrogen-enriched dialysate: two case reports.","authors":"Ryoichi Nakazawa, Shintaro Nagami, Hiroshi Nozaki, Minako Yataka, Kazuhiro Akiyama, Takashi Uchino, Nakanobu Azuma","doi":"10.4103/mgr.MEDGASRES-D-24-00024","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00024","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"122-123"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung function and blood gas of rats after different protocols of hypobaric exposure.","authors":"Lijun Yin, Yukun Wen, Zhixin Liang, Zhenbiao Guan, Xuhua Yu, Jiajun Xu, Shifeng Wang, Wenwu Liu","doi":"10.4103/mgr.MEDGASRES-D-24-00039","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00039","url":null,"abstract":"<p><p>High-altitude pulmonary edema (HAPE) is a common disease observed in climbers, skiers and soldiers who ascend to high altitudes without previous acclimatization. Thus, a reliable and reproducible animal model that can mimic the mechanisms of pathophysiologic response in humans is crucial for successful investigations. Our results showed that exposure to 4500 m for 2 days had little influence on lung function or blood gas, and exposure to 6000 m for 2 or 3 days could change lung function and blood gas, but most parameters returned to nearly normal levels within 48 hours. This study indicates that exposure to 6000 m for 3 days may induce evident lung edema and significantly alter lung function and blood gas, which may mimic HAPE in clinical practice. Thus, this animal model of HAPE may be used in future studies on HAPE.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"180-187"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitric oxide-based treatments improve wound healing associated with diabetes mellitus.","authors":"Zahra Bahadoran, Parvin Mirmiran, Farhad Hosseinpanah, Khosrow Kashfi, Asghar Ghasemi","doi":"10.4103/mgr.MEDGASRES-D-24-00020","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00020","url":null,"abstract":"<p><p>Non-healing wounds are long-term complications of diabetes mellitus (DM) that increase mortality risk and amputation-related disability and decrease the quality of life. Nitric oxide (NO·)-based treatments (i.e., use of both systemic and topical NO· donors, NO· precursors, and NO· inducers) have received more attention as complementary approaches in treatments of DM wounds. Here, we aimed to highlight the potential benefits of NO·-based treatments on DM wounds through a literature review of experimental and clinical evidence. Various topical NO·-based treatments have been used. In rodents, topical NO·-based therapy facilitates wound healing, manifested as an increased healing rate and a decreased half-closure time. The wound healing effect of NO·-based treatments is attributed to increasing local blood flow, angiogenesis induction, collagen synthesis and deposition, re-epithelization, anti-inflammatory and anti-oxidative properties, and potent broad-spectrum antibacterial effects. The existing literature lacks human clinical evidence on the safety and efficacy of NO·-based treatments for DM wounds. Translating experimental favors of NO·-based treatments of DM wounds into human clinical practice needs conducting clinical trials with well-predefined effect sizes, i.e., wound reduction area, rate of wound healing, and hospital length of stay.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"23-35"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury?","authors":"Cesar V Borlongan, Amir Hadanny","doi":"10.4103/mgr.MEDGASRES-D-24-00029","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00029","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"132-133"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of hyperbaric hyperoxic lung injury in rats.","authors":"Lijun Yin, Zhenbiao Guan, Jiajun Xu, Xuhua Yu, Yukun Wen, Shifeng Wang, Wenwu Liu","doi":"10.4103/mgr.MEDGASRES-D-24-00030","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00030","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"129-131"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperbaric oxygen for moderate-to-severe traumatic brain injury: outcomes 5-8 years after injury.","authors":"Zhihua Zhang, Zhenwei Li, Shuyang Li, Bing Xiong, You Zhou, Chaohong Shi","doi":"10.4103/mgr.MEDGASRES-D-24-00018","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00018","url":null,"abstract":"<p><p>The use of hyperbaric oxygen (HBO 2 ) in the field of traumatic brain injury (TBI) is becoming more widespread and increasing yearly, however there are few prognostic reports on long-term functional efficacy. The aim of this study was to assess the functional prognosis of patients with moderate-to-severe TBI 5-8 years following HBO 2 treatments and to explore the optimal HBO 2 regimen associated with prognosis, using a retrospective study. Clinical data were retrospectively collected as a baseline for patients with moderate-to-severe TBI treated with HBO 2 during inpatient rehabilitation from January 2014 to December 2017. The primary outcome measure was the Disability Rating Scale (DRS) and the secondary outcome measure was the Glasgow Outcome Scale. A total of 133 patients enrolled, with 9 (6.8%) dying, 41 (30.8%) remaining moderately disabled or worse (DRS scores 4-29), 83 (62.4%) remaining partially/mildly disabled or no disability (DRS scores 0-3). Logistic regression analysis revealed that age at injury (odds ratio (OR), 0.96; 95% confidence interval (CI), 0.92-0.99), length of intensive care unit stay (OR, 0.94; 95% CI, 0.88-0.99), and HBO 2 sessions (OR, 0.97; 95% CI, 0.95-0.99) were variables that independently influenced long-term prognosis. Cubic fitting models revealed that 14 and 21.6 sessions of HBO 2 could be effective for moderate and severe TBI, respectively. This study highlighted that HBO 2 in moderate-to-severe TBI may contribute to minimize death and reduce overall disability in the long-term. However, clinicians should be cautious of the potential risk of adverse long-term prognosis from excessive HBO 2 exposure when tailoring individualized HBO 2 regimens for patients with moderate-to-severe TBI. The study was registered on ClinicalTrials.gov (NCT05387018) on March 31, 2022.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":" ","pages":"156-163"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia and its environmental impact: approaches to minimize exposure to anesthetic gases and reduce waste.","authors":"Khalid Samad, Muhammad Saad Yousuf, Hameed Ullah, Syed Shabbir Ahmed, Khalid Maudood Siddiqui, Asad Latif","doi":"10.4103/mgr.MEDGASRES-D-23-00059","DOIUrl":"10.4103/mgr.MEDGASRES-D-23-00059","url":null,"abstract":"<p><p>In today's era of modern healthcare, the intersection between medical practices and environmental responsibility has gained significant attention. One such area of focus is the practice of anesthesia, which plays a crucial role in various surgical procedures. Anesthetics such as nitrous oxide and volatile halogenated ethers (desflurane, isoflurane, sevoflurane) are examples of medical gases that are strong greenhouse gases that contribute to global warming. During medical procedures, most of these anesthetic agents are released into the atmosphere, which exacerbates their influence on the environment. Also anesthesia delivery systems have traditionally utilized high flow rates of gases, leading to not only excessive consumption but also a considerable environmental impact in terms of greenhouse gas emissions. However, the emergence of low-flow anesthesia (LFA) presents a promising solution for achieving emission reduction and cost savings, thereby aligning healthcare practices with sustainability goals. Understanding LFA involves the administration of anesthetic gases to patients at reduced flow rates compared to conventional high-flow methods. This practice requires precision in gas delivery, often incorporating advanced monitoring and control systems. By optimizing gas flow to match the patient's requirements, LFA minimizes wastage and excessive gas release into the environment, subsequently curbing the carbon footprint associated with healthcare operations. Decreasing volatile anesthetic delivery provides safe and effective strategies for anesthesia providers to decrease costs and reduce environmental pollution. Current literature support in favor of LFA represents an area of cost containment and an opportunity to lessen the environmental impact of anesthesia. This article will cover the concept of LFA, the distinctions between low flow and minimal flow, and the potential advantages of LFA, such as those related to patient safety, the environment, and the economy.</p>","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"101-109"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cold atmospheric plasma for breast cancer treatment: what next?","authors":"Catarina Almeida-Ferreira, Francisca Rodrigues, Carlos Miguel Marto, Maria Filomena Botelho, Mafalda Laranjo","doi":"10.4103/mgr.MEDGASRES-D-24-00043","DOIUrl":"10.4103/mgr.MEDGASRES-D-24-00043","url":null,"abstract":"","PeriodicalId":18559,"journal":{"name":"Medical Gas Research","volume":"15 1","pages":"110-111"},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}