Micro and Nanosystems最新文献

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Polythiophene/Copper Vanadate Nanoribbons and their ElectrochemicalSensing Properties for Detecting Benzoic Acid 用于检测苯甲酸的聚噻吩/钒酸铜纳米带及其电化学传感特性
Micro and Nanosystems Pub Date : 2024-07-09 DOI: 10.2174/0118764029318334240625115029
Xingxing Zhu, Yong Zhang, Qianmin Cong, Zhengyu Cai, Lizhai Pei
{"title":"Polythiophene/Copper Vanadate Nanoribbons and their Electrochemical\u0000Sensing Properties for Detecting Benzoic Acid","authors":"Xingxing Zhu, Yong Zhang, Qianmin Cong, Zhengyu Cai, Lizhai Pei","doi":"10.2174/0118764029318334240625115029","DOIUrl":"https://doi.org/10.2174/0118764029318334240625115029","url":null,"abstract":"\u0000\u0000Excessive intake of benzoic acid may cause serious diseases, including\u0000disordered metabolism, abdominal pain, and diarrhea. Hence, it is important to explore a reliable\u0000method to determine the quantity of benzoic acid for protecting human health. In this regard, polythiophene/copper vanadate nanoribbon composites act as electrode materials for the detection of\u0000benzoic acid.\u0000\u0000\u0000\u0000The objective of this research was to synthesize polythiophene/copper vanadate nanoribbons via an in-situ polymerization approach and evaluate their electrochemical performance for the\u0000detection of benzoic acid.\u0000\u0000\u0000\u0000Polythiophene/copper vanadate nanoribbons were obtained via an in-situ polymerization\u0000approach. The obtained composite nanoribbons were analyzed using X-ray diffraction, electron microscopy, Fourier Transform Infrared Spectroscopy, and electrochemical method.\u0000\u0000\u0000\u0000Amorphous polythiophene nanoparticles with a size of less than 100 nm were homogeneously attached to the copper vanadate nanoribbons. Electrochemical sensing properties of the polythiophene/copper vanadate nanoribbons modified electrode for detecting benzoic acid were analyzed using the Cyclic Voltammetry (CV) method. An irreversible CV peak was observed at +0.36\u0000V in 0.1 M KCl solution with 2 mM benzoic acid. The polythiophene/copper vanadate nanoribbons\u0000modified electrode indicated a linear range of 0.001-2 mM with the limit of detection (LOD) of\u00000.29 µM.\u0000\u0000\u0000\u0000Polythiophene greatly enhanced the electrochemical sensing properties of copper vanadate nanoribbons. Polythiophene/copper vanadate nanoribbons modified electrode was found to be\u0000stable and repeatable owing to the synergistic effect of various components.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Release Kinetics of Sulfentrazone from Chitosan Clay SulfentrazoneNanocomposite 壳聚糖粘土硫腙纳米复合材料中硫腙的释放动力学
Micro and Nanosystems Pub Date : 2024-07-09 DOI: 10.2174/0118764029301198240530101307
Praveen Kumar Mishra, G. Usmani, Ajaygiri Goswami, Achintya Mondal
{"title":"Release Kinetics of Sulfentrazone from Chitosan Clay Sulfentrazone\u0000Nanocomposite","authors":"Praveen Kumar Mishra, G. Usmani, Ajaygiri Goswami, Achintya Mondal","doi":"10.2174/0118764029301198240530101307","DOIUrl":"https://doi.org/10.2174/0118764029301198240530101307","url":null,"abstract":"\u0000\u0000With a rational objective to reduce groundwater contamination from pesticides and thereby reducing ecotoxicological effect of pesticide, present research programme was\u0000carried out. Sulfentrazone is a well-known effective pesticide that is used for soybean crops. But at\u0000the same time, sulfentrazone is known for its high leaching potential through soil and could lead to\u0000ground water contamination\u0000\u0000\u0000\u0000So we have synthesized a novel chitosan clay nanocomposites of sulfentrazone at three different concertations of sulfentrazone, 37.64%, 52.44% and 59.85% and its release pattern was studied at three different buffer systems like pH 2, pH 4 and pH 6. Release pattern of Sulfentrazone has\u0000been quantified by using High Performance Liquid Chromatography (HPLC) technique. Various\u0000mathematical tools have been applied to understand the release kinetics of chitosan clay sulfentrazone nanocomposites\u0000\u0000\u0000\u0000Correlation coefficient (R2) of many models has been plotted and the Huguchi model was\u0000found to be the most suitable for these nanocomposites. The salient finding of this study is that the\u0000release rates of sulfentrazone at pH 4 is 68.39%, 42.62% and 37.75% after 8 hours at three different\u0000loading. This release pattern is higher than the release pattern at pH 6 and pH 2.\u0000\u0000\u0000\u0000Based on these release data, it is very clear that chitosan clay sulfentrazone nanocomposite can control the release of sulfentrazone at regular soil pH conditions, which is pH 6.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmaceutical Applications and Advances with Zetasizer: An Essential Analytical Tool for Size and Zeta Potential Analysis Zetasizer 的制药应用与进展:粒度和 Zeta 电位分析的基本分析工具
Micro and Nanosystems Pub Date : 2024-06-13 DOI: 10.2174/0118764029301470240603051432
Sonakshi Garg, Preeti Patel, Ghanshyam Das Gupta, B. Kurmi
{"title":"Pharmaceutical Applications and Advances with Zetasizer: An Essential Analytical Tool for Size and Zeta Potential Analysis","authors":"Sonakshi Garg, Preeti Patel, Ghanshyam Das Gupta, B. Kurmi","doi":"10.2174/0118764029301470240603051432","DOIUrl":"https://doi.org/10.2174/0118764029301470240603051432","url":null,"abstract":"\u0000\u0000Zetasizer is an advanced device that measures various properties of particles or molecules\u0000suspended in a liquid medium. It is extensively used for evaluating the size of nanoparticles,\u0000colloids, and biomolecular particles, and for determining particle charge. There are several analytical\u0000techniques by which the size, zeta potential, and molecular weight can be determined, like Dynamic\u0000Light Scattering (DLS) that measures the size of particles in dispersed systems, which can\u0000range from sub-nanometers to several micrometers in diameter. Electrophoretic Light Scattering\u0000(ELS) analyzes the mobility and charge of particles, also known as the zeta potential. Static Light\u0000Scattering (SLS) determines the molecular weight of particles in a solution. The Zetasizer is part of\u0000the Zetasizer Advance range of benchtop systems available for laboratory use. The Zetasizer Ultra\u0000model offers unique measurement capabilities, such as Multi-angle Dynamic Light Scattering\u0000(MADLS) and particle concentration. These features offer a deeper understanding of samples, making\u0000the Zetasizer a vital instrument in numerous scientific and industrial applications. In this review,\u0000we have discussed Zetasizer’s principles for the determination of particle size, zeta potential,\u0000and molecular weight, along with its qualification and applications in different formulations.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141345634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global RC Interconnects with ADL Buffers for Low-Power Applications 针对低功耗应用的带 ADL 缓冲器的全局 RC 互连器件
Micro and Nanosystems Pub Date : 2024-05-17 DOI: 10.2174/0118764029298466240508091306
Himani Bhardwaj, Shruti Jain, Harsh Sohal
{"title":"Global RC Interconnects with ADL Buffers for Low-Power Applications","authors":"Himani Bhardwaj, Shruti Jain, Harsh Sohal","doi":"10.2174/0118764029298466240508091306","DOIUrl":"https://doi.org/10.2174/0118764029298466240508091306","url":null,"abstract":"\u0000\u0000Interconnects are an essential requirement for any circuit completion. They\u0000are utilised to connect two or more blocks, yet when creating a circuit, certain problems have been\u0000observed. Scaling back technology is one such problem.\u0000\u0000\u0000\u0000With technology scaled down their aspects change which can straightforwardly affect the\u0000circuit boundaries. Because of this, the time constant and power consumption in the interconnect circuits\u0000has increased. Certain wire (RC) models and techniques have previously been characterized to\u0000control these performance parameters however in this paper, authors have proposed a new interconnect\u0000structure with a buffer insertion technique using adiabatic dynamic logic (ADL).\u0000\u0000\u0000\u0000To optimise power, a Schmitt trigger is inserted as a buffer between lengthy interconnect\u0000circuits utilising an energy-recovery mechanism. The TSPICE tool is used to model and simulate the\u0000entire circuit.\u0000\u0000\u0000\u0000The suggested model's performance is compared to that of other cutting-edge methods.\u0000\u0000\u0000\u0000The complete circuits are modelled and simulated using the SPICE tool. A performance comparison is done between the existing model and the proposed model.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141126930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transethosomal Carrier of Curcumin for Improved Topical Delivery:Optimization, In-vitro and Stability Assessment 用于改善局部给药的姜黄素转运载体:优化、体外试验和稳定性评估
Micro and Nanosystems Pub Date : 2024-04-09 DOI: 10.2174/0118764029301002240326144814
R. Rathod, P. Pawar
{"title":"Transethosomal Carrier of Curcumin for Improved Topical Delivery:\u0000Optimization, In-vitro and Stability Assessment","authors":"R. Rathod, P. Pawar","doi":"10.2174/0118764029301002240326144814","DOIUrl":"https://doi.org/10.2174/0118764029301002240326144814","url":null,"abstract":"\u0000\u0000Currently, there is a clear lack of effective topical treatments for psoriasis. In\u0000light of this unaddressed requirement, the work intends to develop, enhance, and assess the effectiveness\u0000of a curcumin transethosomal gel for managing psoriasis. This work signifies the delivery\u0000of a potential solution to fill the gap in topical psoriasis treatment.\u0000\u0000\u0000\u0000Curcumin-loaded transethosomes were prepared using a mechanical dispersion\u0000method. An initial study was conducted to determine the ideal concentrations of Lipoid\u0000S100 and Isopropyl Myristate (IPM). To refine the ultimate transethosomal formulation, a full factorial\u0000design (32) was employed, incorporating different levels of Lipoid S100 and IPM. Drug release\u0000investigations and pharmacokinetics assessments of curcumin concentrations were performed\u0000using a specialized dissolution apparatus and an animal model, respectively.\u0000\u0000\u0000\u0000The characterization profile and analytical examinations have affirmed the stability of the\u0000formulation throughout the study duration. Our findings indicate that the drug release mechanism\u0000conforms to a diffusion pattern akin to Fickian transport. Furthermore, In-vivo investigations revealed\u0000that the curcumin concentration in the bloodstream after oral administration was significantly\u0000superior to that of the conventional formulation.\u0000\u0000\u0000\u0000Using curcumin-loaded transethosomes extends drug contact time and facilitates controlled\u0000drug release, leading to enhanced bioavailability, decreased dosage needs, and heightened\u0000patient safety.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140725990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Microsponges in Dermatology: Opportunities and HurdlesAhead 探索微海绵在皮肤科中的应用:机遇与挑战并存
Micro and Nanosystems Pub Date : 2024-04-08 DOI: 10.2174/0118764029295903240328054858
Prerna Sharma, Peeyush Kaushik, Satish Kumar Sharma, Sanchit Dhankar, Nitika Garg, Nidhi Rani
{"title":"Exploring Microsponges in Dermatology: Opportunities and Hurdles\u0000Ahead","authors":"Prerna Sharma, Peeyush Kaushik, Satish Kumar Sharma, Sanchit Dhankar, Nitika Garg, Nidhi Rani","doi":"10.2174/0118764029295903240328054858","DOIUrl":"https://doi.org/10.2174/0118764029295903240328054858","url":null,"abstract":"\u0000\u0000Microsponges are porous, polymeric particles that have been extensively explored in the\u0000field of dermatology. They offer numerous advantages as a topical delivery system, including controlled\u0000release of active ingredients, enhanced bioavailability, and improved stability. Microsponges\u0000have been used for a wide range of dermatological applications, including the treatment of acne,\u0000psoriasis, and other skin disorders. This review article provides an overview of the various applications\u0000of microsponges in dermatology, along with the challenges associated with their development\u0000and use. The article begins with a brief introduction to microsponges, the benefits of microsponges,\u0000and their properties. It then discusses the different methods of microsponge preparation, such as\u0000emulsion solvent evaporation and spray drying, along with their mechanism of drug release and also\u0000applications of microsponges in dermatology, including their use in the treatment of acne, psoriasis,\u0000and other skin disorders, are discussed in detail. Overall, microsponges have shown great promise as\u0000a topical delivery system in dermatology, and their continued development and use will likely lead\u0000to significant advances in the field.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140731279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SmartLipids: Ushering in a New Era of Lipid Nanoparticles for Drug Delivery 智能脂质:开创脂质纳米颗粒给药新时代
Micro and Nanosystems Pub Date : 2024-04-03 DOI: 10.2174/0118764029294004240318094405
Bhawna Sharma, Iti Chauhan, Gaurav Kumar, Raj kumar Tiwari
{"title":"SmartLipids: Ushering in a New Era of Lipid Nanoparticles for Drug Delivery","authors":"Bhawna Sharma, Iti Chauhan, Gaurav Kumar, Raj kumar Tiwari","doi":"10.2174/0118764029294004240318094405","DOIUrl":"https://doi.org/10.2174/0118764029294004240318094405","url":null,"abstract":"\u0000\u0000In the realm of drug delivery, lipid nanoparticles have emerged as versatile carriers, offering\u0000enhanced encapsulation, protection, and targeted delivery of therapeutic agents. Among these\u0000innovative systems, SmartLipids stands out as a groundbreaking advancement, representing the latest\u0000generation of lipid nanoparticles. Characterized by their unique \"chaotic\" and disordered particle\u0000matrix structure, SmartLipids exhibit remarkable properties that set them apart from conventional\u0000drug delivery systems. This comprehensive review delves into the intricate world of SmartLipids,\u0000unraveling their distinctive features and exploring their immense potential in the field of drug delivery.\u0000It meticulously outlines their production methods, shedding light on the solvent-free, highpressure\u0000homogenization technique that ensures biocompatibility and safety. The review meticulously\u0000examines the physicochemical characterization of SmartLipids, providing insights into their particle\u0000size, morphology, and encapsulation efficiency. It further delves into their in vitro and in vivo\u0000performance, highlighting their ability to enhance drug solubility, permeability, and bioavailability.\u0000The study collectively underscores the versatility and customizable nature of SmartLipids, emphasizing\u0000their suitability for a wide range of drug delivery applications. From encapsulating hydrophilic,\u0000lipophilic, and amphiphilic compounds to tailoring specific release profiles, SmartLipids offer\u0000a remarkable degree of flexibility in drug delivery strategies.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140749991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Investigation on Efficacy of Eudragit RS 100 Polymer inProlonging Glibenclamide Release by Intragastric Floating MicrosphereFormulation and Physicochemical Evaluation Eudragit RS 100 聚合物通过胃内漂浮微球配方延长格列本脲释放时间的功效实验研究与理化评价
Micro and Nanosystems Pub Date : 2024-03-28 DOI: 10.2174/0118764029286890240314060427
Devika Tripathi, Princy Yadav, Gauransh Mishra, A. Rai
{"title":"Experimental Investigation on Efficacy of Eudragit RS 100 Polymer in\u0000Prolonging Glibenclamide Release by Intragastric Floating Microsphere\u0000Formulation and Physicochemical Evaluation","authors":"Devika Tripathi, Princy Yadav, Gauransh Mishra, A. Rai","doi":"10.2174/0118764029286890240314060427","DOIUrl":"https://doi.org/10.2174/0118764029286890240314060427","url":null,"abstract":"\u0000\u0000The amalgamation of targeted transportation and enhancement of the release\u0000profile of the active pharmaceutical ingredient is a contemporary trend in the evolution of oral\u0000medicinal products. A renowned method to actualize this concept is to develop floating gastroretentive\u0000delivery systems that ensure an extended stay of the dosage form on the gastric surface. The\u0000success of drug delivery is largely dependent on the type of polymer used that sustains the release\u0000and avoids any toxic effects. Intragastric floating drug delivery systems are designed to remain\u0000buoyant in the stomach without affecting the gastric emptying rate for a prolonged period. This allows\u0000for a slow release of the drug in the stomach, which can be particularly beneficial for drugs\u0000with a narrow absorption window, like Glibenclamide, an anti-diabetic medication.\u0000\u0000\u0000\u0000The current research focused on the sustained drug delivery of Glibenclamide as intragastric\u0000floating microspheres. The goal was to adjust the floatation and drug release pattern using\u0000Eudragit RS 100 and magnesium stearate as a droplet stabilizer. Different batches of floating microspheres\u0000were optimized based on the polymer, drug-polymer concentration, and the amount of\u0000magnesium stearate. The strategy aimed to enhance the effectiveness of Glibenclamide, particularly\u0000for individuals with diabetes, by facilitating a controlled and consistent release of the drug in the\u0000gastric environment.\u0000\u0000\u0000\u0000The solvent evaporation method was used to create four batches of intragastric\u0000microspheres. The maximum absorbance of the drug, also known as lambda max, was observed\u0000at 212 nm. The prepared batches were evaluated for various in-vitro physicochemical parameters.\u0000The average particle size was found to be 619 nm. Rheological studies indicated excellent\u0000flow properties. The microspheres exhibited in-vitro buoyancy for up to 7 hours\u0000\u0000\u0000\u0000The entrapment efficiency was as high as 93.19%. Scanning Electron Microscopy (SEM)\u0000analysis revealed that the microspheres have a porous structure, which allows for the easy movement\u0000of solvents and solutes into and out of the microspheres. Differential Scanning Calorimetry\u0000(DSC) and Thermogravimetric Analysis (TGA) indicated the physical and chemical properties of\u0000the microspheres. All in-vitro drug release and kinetic studies for the optimized batch (F-M4) revealed\u0000that Eudragit RS 100 effectively sustained the intragastric delivery of Glibenclamide.\u0000\u0000\u0000\u0000Floating drug delivery systems enhance oral dosage forms and the range of APIs by\u0000ensuring targeted gastric delivery and modified release. This improves bioavailability, reduces drug\u0000losses, and partially mitigates side effects.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrochemical Sensing of Vitamin C Using Graphene/ Poly-Thionine Composite Film Modified Electrode 利用石墨烯/聚硫氨酸复合膜改性电极对维生素 C 进行电化学传感
Micro and Nanosystems Pub Date : 2024-02-23 DOI: 10.2174/0118764029290865240209072023
Ridhu Varshini Murugan, V. Magesh, K. Vijayalakshmi, R. Atchudan, Sandeep Arya, A. Sundramoorthy
{"title":"Electrochemical Sensing of Vitamin C Using Graphene/ Poly-Thionine Composite Film Modified Electrode","authors":"Ridhu Varshini Murugan, V. Magesh, K. Vijayalakshmi, R. Atchudan, Sandeep Arya, A. Sundramoorthy","doi":"10.2174/0118764029290865240209072023","DOIUrl":"https://doi.org/10.2174/0118764029290865240209072023","url":null,"abstract":"\u0000\u0000Gastric irritation and kidney problems occur due to excess ascorbic acid\u0000content, whereas the lack of ascorbic acid in the human body leads to poor wound healing, muscle\u0000degeneration, and anemia.\u0000\u0000\u0000\u0000Herein, we report the development of an electrochemical sensor for the detection of\u0000ascorbic acid using poly-thionine/ graphene (P-Th/Gr) modified glassy carbon electrode (GCE) in\u00000.1 M phosphate buffer solution (PBS) (pH 7.4). Electrostatically fused graphene affixed with\u0000poly-thionine was successfully illustrated for effective voltammetric sensing of ascorbic acid.\u0000\u0000\u0000\u0000FE-SEM indicated the blended edge of a 2D graphene sheet with a deposited thin\u0000layer of polymer, which confirmed the formation of a poly-thionine/ graphene composite. The cyclic\u0000voltammetry (CV) technique was utilized for the electrochemical ascorbic acid (AsA, Vitamin\u0000C) assay.\u0000\u0000\u0000\u0000With the increased concentrations of AsA, the oxidation peak current of ascorbic acid increased\u0000at 0.0 V, and the overpotential showed a decrease compared to bare GCE. The effect of\u0000scan rate on cyclic voltammograms was recorded with 500 μM of ascorbic acid from 10 mV/s to\u0000250 mV/s, which indicated that AsA oxidation is a diffusion-controlled process on poly-thionine/\u0000graphene-modified electrode.\u0000\u0000\u0000\u0000With the increased concentrations of AsA, the oxidation peak current of ascorbic acid increased at 0 V and also the over potential showed a decrease compared to bare GCE. The effect of scan rate on cyclic voltammograms (CVs) were recorded with 500 μM of ascorbic acid from 10 mV/s to 250 mV/s, which indicated that AsA oxidation is a surface-controlled process on polythionine/graphene modified electrode.\u0000\u0000\u0000\u0000It was concluded that a poly-thionine/ graphene composite-based sensor could be useful\u0000for the determination of ascorbic acid in various biological samples.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140436672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical and Morphological Analysis of Aramid Fiber (PPTA), GlassWool (GW), Aluminum (Al), and Silicon Carbide (SiC) ParticlesEmbedded High-density Polyethylene (HDPE) Hybrid Composites 芳纶纤维 (PPTA)、玻璃丝 (GW)、铝 (Al) 和碳化硅 (SiC) 粒子嵌入高密度聚乙烯 (HDPE) 混合复合材料的力学和形态分析
Micro and Nanosystems Pub Date : 2024-01-29 DOI: 10.2174/0118764029287700240116102226
Rajib Ahmed, Mahbub Hasan, Md. Rezaul Karim Sheikh, A. Faruqui
{"title":"Mechanical and Morphological Analysis of Aramid Fiber (PPTA), Glass\u0000Wool (GW), Aluminum (Al), and Silicon Carbide (SiC) Particles\u0000Embedded High-density Polyethylene (HDPE) Hybrid Composites","authors":"Rajib Ahmed, Mahbub Hasan, Md. Rezaul Karim Sheikh, A. Faruqui","doi":"10.2174/0118764029287700240116102226","DOIUrl":"https://doi.org/10.2174/0118764029287700240116102226","url":null,"abstract":"\u0000\u0000Composite research is adopting innovative materials in the current period\u0000due to their better qualities, such as being lightweight, having excellent mechanical properties, being\u0000relatively inexpensive, having a low coefficient of thermal expansion, etc.\u0000\u0000\u0000\u0000Composite materials play a crucial part in this challenge, with the fast market growth for\u0000lightweight and high-performance materials. In the present research, different weight percentages of\u0000aramid fiber, glass wool, aluminum, and silicon carbide-reinforced high-density polyethylene hybrid\u0000composite are introduced. The degree of adhesion between the matrix and reinforcement was determined through microstructural investigation utilizing an optical and scanning electronic microscope.\u0000\u0000\u0000\u0000Mechanical properties (tensile behaviors, flexural behavior, impact strength and hardness\u0000property) of the fabricated composites are investigated. Comparative study of mechanical properties\u0000for different combinations of fabricated composites reveals an increase in elongation at break, flexural\u0000strength, flexural modulus and hardness, while tensile strength and impact strength have decreased\u0000sequentially from 5 to 40 wt.%.\u0000\u0000\u0000\u0000The mechanical properties of HDPE-PPTA-GW-Al-SiC hybrid composites obtained at\u000040 wt.% PPTA [Poly (p-phenylene terephthalamide)], GW (glass wool), Al, and SiC powder loading\u0000are superior as compared to other hybrid composites.\u0000","PeriodicalId":18543,"journal":{"name":"Micro and Nanosystems","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140489872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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