Medicine Science | International Medical Journal最新文献

{"title":"The mediating role of resilience and perceived stress in the relationship between childhood traumas and depression in young adults","authors":"Emre Ciydem, E. Ozturk, Osman Usta, Gorkem Derin","doi":"10.5455/medscience.2023.06.096","DOIUrl":"https://doi.org/10.5455/medscience.2023.06.096","url":null,"abstract":"It is still unclear whether childhood traumas cause depression by first decreasing the individual's resilience and impairing stress perception or by first increasing the individual's stress perception and impairing resilience. The aim of this study is to investigate the mediating role of resilience and perceived stress in the relationship between childhood trauma and depression in young adults. The convenience sample of the cross-sectional correlational study consisted of 481 young adults with at least one childhood trauma. The data was analysed with structural equation modeling. Childhood traumas may increase perceived stress level by decreasing resilience and both of them may lead to depressive symptoms. At the same time, it has been found that childhood traumas may decrease resilience by increasing the perceived stress level and both may lead to depressive symptoms. The childhood traumas-resilience-perceived stress-depression pathway and childhood traumas-perceived stress-resilience-depression pathway were found to be significant.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77949645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of some biochemical parameters of pediatric patients hospitalized for rotavirus in Şirnak Province: A retrospective review","authors":"Erhan Sonmez, Veysel Tahiroğlu, Erkam Coşkun, N. Alayunt","doi":"10.5455/medscience.2023.07.100","DOIUrl":"https://doi.org/10.5455/medscience.2023.07.100","url":null,"abstract":"Rotavirus gastroenteritis is an important cause of worldwide morbidity and mortality in infants and children. The main cause of mortality is dehydration due to fluid loss and malnutrition. This study aims to examine the guiding parameters of uric acid and creatinine levels in the detection of dehydration and fluid deficit and inpatient management in cases of rotavirus gastroenteritis. Children who applied to Şirnak State Hospital, Pediatrics Polyclinics, children (6 months-18 years old) whose faecal samples were sent to the laboratory by the research pediatrician considering the diagnosis of rotavirus and whose microbiological examinations were confirmed by immunochromatographic methods (6 months-18 years old), were included in the study by scanning the system. When positive patients were evaluated, the mean age for serum uric acid was 1.06±1.53 and the mean age for serum creatinine was 1.10±1.37. The median value was 3.75 mg/dL in negative patients with serum uric acid levels, and 5.25 mg/dL in positive patients, which was statistically significant (p<0.01). The median value of serum creatinine level was 0.41 mg/dL in negative patients and 0.43 mg/dL in positive patients, which was statistically significant (p<0.05). With this study carried out in Şirnak province, we think that children in the region are severely affected by the rotavirus and face severe dehydration. Therefore, we think that all parameters affected by rotavirus should be evaluated according to regions and parents should be educated about the importance of rotavirus vaccine in the prevention of rotavirus gastroenteritis.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80341981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of serum vaspin level on infarct volume and severity in patients with acute ischemic stroke","authors":"Filiz Demirdogen, G. Ozdemir, G. Akcay, Ibrahim Iyigun","doi":"10.5455/medscience.2023.03.040","DOIUrl":"https://doi.org/10.5455/medscience.2023.03.040","url":null,"abstract":"Stroke has a major impact worldwide in terms of mortality and morbidity. The aim of our research was to determine the effect of serum Vaspin level on acute ischemic stroke and to investigate the relationship between serum Vaspin level, National Institutes of Health Stroke Scale (NIHSS) and infarct volume. This study was carried out in 100 patients hospitalized with acute ischemic stroke diagnosis in the Neurology Department of Yakutiye Research Hospital of Atatürk University Faculty of Medicine and 80 healthy controls. The age and sex of the patient and control groups were consistent. Patients who met the following criteria were selected to be included in the study. Exclusion criteria: patients with ischemic stroke presenting after the first 24 hours to overcome the potential bias associated with inflammatory conditions, patients diagnosed with rheumatic and autoimmune diseases, diseases that cause hypoxia and coronary artery disease. Vaspin levels were measured and compared in patients with acute ischemic stroke (AIS) and in the control group. NIHSS calculated. Infarct volume was also measured with Cavalieri's principle. The correlation between them was calculated statistically. Vaspin level was higher in patients with ischemic stroke compared to the control group (825 vs. 939; p<0.001). Vaspin levels were significantly higher in patients who had acute ischemic stroke. Since examination of Vaspin levels in patients presented with acute ischemic stroke suggested the severity of the stroke, it was found to be important in terms of mortality and morbidity affiliated with it.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80456917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism","authors":"Hakan Şıvgın, M. Bostan","doi":"10.5455/medscience.2022.11.239","DOIUrl":"https://doi.org/10.5455/medscience.2022.11.239","url":null,"abstract":"We aimed to investigate correlation between perioperative biochemical values and adenoma volume, the effects of perioperative biochemical values and clinicopathological variables on postoperative hypocalcemia after parathyroidectomy. A retrospective study planned in tertiary university hospital on patients undergone surgery for primer hyperparathyroidism. Preoperative calcium (first, close to surgery, maximum), PTH (first, close to surgery, maximum), alkaline phosphatase (ALP) and phosphorus (P) values, postoperative calcium (early, late), postoperative PTH (early, late), 24-hour urinary calcium calculation, time from the first diagnosis of elevated calcium until surgery, preoperative hypercalcemia treatments, excised parathyroid gland, histopathologic diagnosis, maximum diameter and volume of the excised parathyroid on histopathologic examination, postoperative intravenous calcium supplement were analyzed. 73 patients were included in the study. The median age of the patients was 54 years (range, 18-82), and 83.6% were female. In univariate analysis, patients who were administrated intravenous (IV) calcium supplement had higher preoperative PTH (p=0.024). adenoma volume correlated moderate with preoperative PTH first (r=0.396, p=0.001), preoperative maximum parathormone (r=0.380, p=0.001), preoperative PTH CS (r=0.432, p<0.001) and preoperative first elevated calcium (r=0.240, p=0.041) levels. We conclude that biochemical parameters and adenoma size are not predictive factors in determining the requirement of IV calcium supplement. Preoperative PTH and calcium levels were moderately associated with adenoma volume.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"30 7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82428277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"YouTube as a source of information on coccydynia","authors":"C. Uz, E. Umay","doi":"10.5455/medscience.2023.01.018","DOIUrl":"https://doi.org/10.5455/medscience.2023.01.018","url":null,"abstract":"In recent years, the use of YouTube for obtaining medical information has increased. In this article, we aimed to determine the usefulness, quality,and reliability of YouTube videos on coccydynia. Coccydynia and \"coccyx pain\" were searched for on YouTube on October 2, 2022. The study comprised 80 of the 120 videos that were discovered as a consequence of the search and met the inclusion criteria. The videos' videometric properties were noted. Depending on whether the content utilized information from evidence-based scientific sources,the videos were separated into two groups: useful and misleading. The measure popularity, the Video Power Index (VPI) was applied. To measure reliability, the modified DISCERN (mDISCERN) was applied. To evaluate quality, the Global Quality Score (GQS) was applied. This study found that 28.7% of the video sources were from physicians and 73.8% of the videos were classified as useful, while 26.2% were classified as misleading. Videos posted by doctors and academic institutions/professional organizations were all in the useful group, while all videos uploaded by independent users and patients were in the misleading group. The useful videos had higher VPI, GQS, and mDISCERN scores, indicating that videos posted by healthcare professionals and academic institutions were more reliable and of higher quality than those from patients and independent users. The significant number of the coccydynia-related YouTube videos were reliable, useful, and of high quality. Healthcare providers should be aware of the value of YouTube's health-related content and maintain high-quality content.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82318098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of lipids on inflammation and DNA damage in diabetes mellitus patients","authors":"G. Gulbay, Y. Kaya","doi":"10.5455/medscience.2023.07.115","DOIUrl":"https://doi.org/10.5455/medscience.2023.07.115","url":null,"abstract":"We aimed to see the effect of lipids on 8-hydroxy-2'-deoxyguanosine (8-OHdG), a marker of DNA damage, and Interleukin-6 (IL-6), an inflammatory cytokine, in Diabetes Mellitus (DM) patients. Serum IL-6, and 8-OHdG levels were determined using kits based on the ELISA principle. The groups were different in terms of total cholesterol, LDL cholesterol and triglyceride. Group 2 (dyslipidemia positive DM positive) was significantly higher than the other groups. There was no statistical difference between group 1 (dyslipidemia negative DM positive) and the control group (p<0.001). 8-OHdG levels differ between groups. The level of 8-OHdG was significantly higher in group 2 compared to the other groups (p<0.001). IL-6 was different between groups. Group 2, IL-6 level was found to be significantly higher than the other groups (p<0.001). A positive correlation was found between serum 8-OHdG level and total cholesterol (r=0.417 p<0.001), LDL cholesterol (r=0.491 p<0.001) and triglyceride (r=0.441 p<0.001). A positive correlation was found between IL-6 and total cholesterol (r=0.522 p<0.001), LDL cholesterol (r=0.646 p<0.001) and triglyceride (r=0.495 p<0.001). IL-6 and 8-OHdG levels are high in dyslipidemic DM patients with a high lipid profile. IL-6 and 8-OHdG levels are elevated in dyslipidemic DM patients with a high lipid profile. IL-6 and 8-OHdG can be used as biomarkers to evaluate dyslipidemic complications seen in DM patients in the early diagnosis.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83192720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mystery of morphometric measurements of the coxal bone","authors":"H. Guler, Emre Uğuz, H. Yılmaz, Hande Taşdemir, Eylem Yalman, G. Uzun","doi":"10.5455/medscience.2023.05.059","DOIUrl":"https://doi.org/10.5455/medscience.2023.05.059","url":null,"abstract":"Coxal bone, which is included in the structure of the pelvic skeleton, is in close relationship with the pelvic organs and great vessels. The aim of this study is to show the harmony between morphometric measurements using the correlation technique, based on the idea that the proportional harmony in different parts of our body will also be in the coxal bone. In the study, 95 dry coxal bone belonging to the Turkish population were examined. In dry bones of adults, the distance between anterior superior iliac spine and posterior superior iliac spine (A), distance between anterior inferior iliac spine and posterior inferior iliac spine (B), distance between anterior superior iliac spine and anterior inferior iliac spine (C), distance between posterior superior iliac spine and posterior inferior iliac spine (D), symphysial surface length (E), symphysial surface width (F), ischial tuberosity width (G), ischion-pubis arm thickness (H), coxal bone length (I), distance between the symphysial surface and the most protruding part of the ischial tuberosity (J) were measured with caliper. There was no statistical difference in the comparison of different measurements made on the right and left coxal bone in our study. In correlation studies, between (B) and (A) (r: 0.566), between (I) and (A) (r: 0.595), between (J) and (A) (r: 0.600), between (E) and (J) (r: 0.563) measurements showed a positive correlation relationship. In this study, excellent agreement was found in different morphometric measurements in coxal bone.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83540981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A society, a disease, a survey and the expected result","authors":"B. Demir, D. Karahan","doi":"10.5455/medscience.2022.11.246","DOIUrl":"https://doi.org/10.5455/medscience.2022.11.246","url":null,"abstract":"COVID-19, which affects the whole world, has affected people, societies and human relations throughout the process. The COVID-19 pandemic both limited people's social lives and changed the perspective of people who carry the virus. Anxiety, fear, haste, loneliness, worry were the most common emotions. In this study, we aimed to evaluate how social warnings affect people, the effects of death risk due to the disease, the side effects of the drugs used on behavior change, and the underlying factors. 189 cases were included in the study. The study was designed in the style of a 20-question questionnaire on the effects of covid-19 and treatment options on the behavior pattern. The responses were evaluated and interpreted as percentages. Variables on family and social behavior related to anxiety, fear, panic, and loneliness caused by COVID-19 and the drugs used in its treatment were observed. Negative effects of COVID-19 were observed in family and community relations. COVID-19 has caused psychological and sociological changes in interpersonal and social behaviors all over the world. There are differences in behavioral patterns among societies. In Turkish society, behavioral changes arising from the characteristic and patriarchal characteristics of the society have been observed. A more detailed assessment of the effects of COVID-19 and subsequent pandemics on the individual and society remains important.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88697317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the findings affecting the treatment decision in cases of adhesive intestinal obstruction","authors":"A. Isler, M. Bozan, A. Şanlı, F. Yaşar","doi":"10.5455/medscience.2022.12.266","DOIUrl":"https://doi.org/10.5455/medscience.2022.12.266","url":null,"abstract":"To establish a standard approach in patient management by determining the parameters that affect the decision of surgical or conservative treatment in adhesive small bowel obstructions. 94 patients who were admitted to the emergency department with symptoms of ileus and were diagnosed with adhesive intestinal obstruction according to clinical, examination and imaging findings were grouped as patients who were followed up with conservative methods (Group 1) and patients who underwent surgery (Group 2). All patients' laboratory values (hemoglobin, white blood cell (WBC), C- reactive protein (CRP), Blodd urea nitrogen (BUN)/creatinin, sodium, potassium, Lactate dehydrogenase (LDH), lactate and amylase) and imaging findings (air-fluid level in direct abdominal X-ray, increase in small intestine diameter (≥3.95 cm) in computerized tomography), wall thickness increase (>3mm), transition zone, fecal sign, and presence of contrast in the colon) were evaluated, and criteria for early surgery and non-operative follow-up-treatment criteria were determined. 72% (n:68) of the patients were classified as Group 1 and 28% (n:26) as Group 2, and no significant difference was found between the groups according to age and gender. Surgical treatment with increased lactate (r:0.326, p=0.001), diameter increase in the small intestine (r:0.299, p=0.003) and wall thickness increase (r:0.540, p<0.001), change in air-fluid levels on direct X-ray ( A significant correlation was found between r:-0.291, p=0.004) and contrast transfer to the colon on tomography (r:-0.668, p<0.001) and the decision for conservative treatment. Although adhesive intestinal obstruction is a condition that can mostly be managed non-operatively, the early surgical decision significantly reduces mortality and morbidity in cases with an operation indication. It was concluded that the standard approach protocol based on laboratory and imaging findings determined in the non-operative or operative treatment management helps in the differential diagnosis and early surgical decision and reduces the length of stay of the patient.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77321935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the prognostic value of blood parameters in patients with rinoserebral mucormycosis","authors":"I. Demir, M. Yalcin, Sukru Aydin, N. Muluk, V. Burulday","doi":"10.5455/medscience.2023.06.095","DOIUrl":"https://doi.org/10.5455/medscience.2023.06.095","url":null,"abstract":"Mucormycosis is a rapidly invasive, life-threatening opportunistic fungal infection, usually in immunocompromised patients. Suspicion, early diagnosis, debridement and anti-fungal treatment are important prognostic factors. The most common clinical manifestations of rhinocerebral mucormycosis are fever, headache, facial and ocular oedema. Invasion of surrounding tissues, the eye, skull base and brain is critical for disease progression. The purpose of this study was to investigate the predictive value of blood parameters in patients with mucormycosis. The preoperative 10-day blood parameters of 23 patients with clinical, radiological and pathological diagnoses of mucormycosis were compared in terms of etiology, gender and site of involvement. When the results were compared, the neutrophil-lymphocyte ratio (NLR) on days 1, 2, 5, 7, 8, 9, and 10 was significantly higher in patients with skull base involvement compared to those without skull base involvement (p<0.05). When comparing the regions of involvement, a significant correlation was found between cranial and turbinate involvement and between lamina papricea and ocular involvement (p<0.05). It was suggested that the NLR rate could be predicted as a poor prognostic factor in patients with mucormycosis.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88464088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}