粘连性肠梗阻对治疗决策的影响

A. Isler, M. Bozan, A. Şanlı, F. Yaşar
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摘要

通过确定影响粘连性小肠梗阻手术或保守治疗决策的参数,建立患者管理的标准方法。将94例因肠梗阻症状入院急诊科,经临床、检查及影像学检查诊断为粘连性肠梗阻的患者分为保守随访组(1组)和手术随访组(2组)。所有患者的实验室指标(血红蛋白、白细胞(WBC)、C反应蛋白(CRP)、血尿素氮(BUN)/肌素、钠、钾、评估乳酸脱氢酶(LDH)、乳酸和淀粉酶)和影像学表现(腹直x线气液水平、计算机断层扫描小肠直径增大(≥3.95 cm)、肠壁厚度增大(>3mm)、过渡区、粪便征象、结肠造影剂),确定早期手术标准和非手术随访治疗标准。72% (n:68)的患者被归为第1组,28% (n:26)的患者被归为第2组,两组间年龄、性别差异无统计学意义。手术治疗乳酸升高(r:0.326, p=0.001),小肠直径增加(r:0.299, p=0.003),肠壁厚度增加(r:0.540, p<0.001), x线直接气液水平变化(r: -0.291, p=0.004)和断层扫描结肠造影剂转移(r:-0.668, p<0.001)与保守治疗的决定有显著相关性。虽然粘连性肠梗阻大多可以非手术治疗,但在有手术指征的病例中,早期手术决定可显著降低死亡率和发病率。由此得出结论,在非手术或手术治疗管理中确定的基于实验室和影像学结果的标准入路方案有助于鉴别诊断和早期手术决策,并缩短患者的住院时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the findings affecting the treatment decision in cases of adhesive intestinal obstruction
To establish a standard approach in patient management by determining the parameters that affect the decision of surgical or conservative treatment in adhesive small bowel obstructions. 94 patients who were admitted to the emergency department with symptoms of ileus and were diagnosed with adhesive intestinal obstruction according to clinical, examination and imaging findings were grouped as patients who were followed up with conservative methods (Group 1) and patients who underwent surgery (Group 2). All patients' laboratory values (hemoglobin, white blood cell (WBC), C- reactive protein (CRP), Blodd urea nitrogen (BUN)/creatinin, sodium, potassium, Lactate dehydrogenase (LDH), lactate and amylase) and imaging findings (air-fluid level in direct abdominal X-ray, increase in small intestine diameter (≥3.95 cm) in computerized tomography), wall thickness increase (>3mm), transition zone, fecal sign, and presence of contrast in the colon) were evaluated, and criteria for early surgery and non-operative follow-up-treatment criteria were determined. 72% (n:68) of the patients were classified as Group 1 and 28% (n:26) as Group 2, and no significant difference was found between the groups according to age and gender. Surgical treatment with increased lactate (r:0.326, p=0.001), diameter increase in the small intestine (r:0.299, p=0.003) and wall thickness increase (r:0.540, p<0.001), change in air-fluid levels on direct X-ray ( A significant correlation was found between r:-0.291, p=0.004) and contrast transfer to the colon on tomography (r:-0.668, p<0.001) and the decision for conservative treatment. Although adhesive intestinal obstruction is a condition that can mostly be managed non-operatively, the early surgical decision significantly reduces mortality and morbidity in cases with an operation indication. It was concluded that the standard approach protocol based on laboratory and imaging findings determined in the non-operative or operative treatment management helps in the differential diagnosis and early surgical decision and reduces the length of stay of the patient.
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