{"title":"Comparison of dexmedetomidine, ketamine, and magnesium sulfate for the prevention of emergence agitation following sevoflurane-based anesthesia in pediatric cardiac catheterization.","authors":"Passaint F Hassan, Amany H Saleh","doi":"10.23736/S0375-9393.24.18306-X","DOIUrl":"https://doi.org/10.23736/S0375-9393.24.18306-X","url":null,"abstract":"<p><strong>Background: </strong>Emergence agitation (EA) is non-purposeful agitation that occurs during the early stages of general anesthesia recovery. This randomized, double-blinded trial aimed to compare the effect of dexmedetomidine, ketamine, and magnesium sulfate on the severity of EA following sevoflurane-based anesthesia in pediatric cardiac catheterization. We examined the fixed doses and assessed the severity of agitation using the Pediatric Anesthesia Emergence Delirium Scale (PAED) score.</p><p><strong>Methods: </strong>One hundred children undergoing heart catheterization without local anesthetic in the skin were randomly divided into four groups. The Dexmedetomidine (D) Group (N.=25) received dexmedetomidine 1 μg/kg IV over 10 min, then 0.5 μg/kg/h. The Magnesium Sulfate (M) Group (N.=25) received 15 mg/k MgSo4 IV over 10 min and then 10 mg/kg/h. The Ketamine (K) Group (N.=25) received 1 mg/kg ketamine over 10 min, then 1 mg/kg/h. The Control (C) Group (N.=25) received 0.9% saline at the same rate as other groups. All medications were diluted in 50 mL 0.9% saline.</p><p><strong>Results: </strong>The dexmedetomidine group exhibited a 0% incidence of EA, compared to 4% in the ketamine group, 12% in the MgSO4 group, and 40% in the control groups (P<0.001). Dexmedetomidine significantly reduced the PAED Scale and pain scores compared to the other groups. The effects of ketamine and MgSO4 on PAED and pain scores were comparable, with both treatments demonstrating significantly lower scores than the control group.</p><p><strong>Conclusions: </strong>Dexmedetomidine exhibited higher efficacy than ketamine and magnesium sulfate in reducing the severity of postoperative EA. However, ketamine and magnesium sulfate demonstrated comparable efficacy, exceeding that of the control group.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-frequency very low-tidal volume ventilation during very high-power short-duration ablation for pulmonary vein isolation. A case series of patients with atrial fibrillation.","authors":"Tomoyuki Saito","doi":"10.23736/S0375-9393.24.18400-3","DOIUrl":"https://doi.org/10.23736/S0375-9393.24.18400-3","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Engin I Turan, Abdurrahman E Baydemir, Ayça S Şahin
{"title":"Efficacy of the quadro-iliac plane block in postoperative pain management for proximal femoral nail surgeries.","authors":"Engin I Turan, Abdurrahman E Baydemir, Ayça S Şahin","doi":"10.23736/S0375-9393.24.18506-9","DOIUrl":"https://doi.org/10.23736/S0375-9393.24.18506-9","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammed H Satici, Mahmut S Tutar, Yasin Tire, Orhan Binici, Osman Çiçekler, Elif Korkmaz, Oğuzhan Pekince, Betül Kozanhan
{"title":"The effect of sacral erector spinae plane block on the quality of recovery after total hip arthroplasty: a prospective, randomized, controlled, multicenter study.","authors":"Muhammed H Satici, Mahmut S Tutar, Yasin Tire, Orhan Binici, Osman Çiçekler, Elif Korkmaz, Oğuzhan Pekince, Betül Kozanhan","doi":"10.23736/S0375-9393.24.18353-8","DOIUrl":"https://doi.org/10.23736/S0375-9393.24.18353-8","url":null,"abstract":"<p><strong>Background: </strong>Total hip arthroplasty, commonly performed to alleviate hip pain and enhance functionality in elderly patients, requires effective postoperative pain management to reduce opioid consumption and its associated side effects. A novel regional anaesthesia technique, the sacral erector spinae plane block, has the potential to enhance the quality of postoperative recovery significantly.</p><p><strong>Methods: </strong>This prospective, randomized, controlled multicenter study investigated the effects of the sacral erector spinae plane block on recovery quality in patients undergoing total hip arthroplasty. The study comprised 50 patients, divided into Group S (patients receiving patients receiving sacral erector spinae plane block [S-ESPB]) and Group C (patients getting just multimodal analgesia). The primary outcome measured was the Quality of Recovery-15 score 24 hours post-surgery. Secondary outcomes included postoperative numerical rating scale scores (A score of 0 indicates no pain, while 10 indicates the most severe pain), total consumption of rescue analgesics, time to first rescue analgesic administration, patient satisfaction, time to first ambulation, the occurrence of complications, and the need for antiemetics.</p><p><strong>Results: </strong>Group S had markedly higher quality of recovery-15 scores compared to Group C (Group S: median 117 percentiles [97-121]; Group C: median 89 percentiles [75-96]; P<0.001). Group S scored higher in postoperative pain, physical comfort, support, emotional state, and general quality of recovery-15 (P<0.001). Nevertheless, the physical independence category ratings were comparable across both groups (P=0.286).</p><p><strong>Conclusions: </strong>Sacral erector spinae plane block is a promising analgesic technique that enhances postoperative recovery and patient comfort in total hip arthroplasty.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic value of circulating IL-6 in adult sepsis: a meta-analysis.","authors":"Kao Gan, Yun Chen, Lanting Tao, Jiqiang Li","doi":"10.23736/S0375-9393.24.18100-X","DOIUrl":"10.23736/S0375-9393.24.18100-X","url":null,"abstract":"<p><strong>Introduction: </strong>In recent years, numerous studies have been published on the diagnostic performance of circulating IL-6 levels in adult sepsis, but the conclusions are not consistent. This meta-analysis aims to systematically evaluate the accuracy of circulating IL-6 in the diagnosis of adult sepsis.</p><p><strong>Evidence acquisition: </strong>Literature on the diagnostic value of circulating IL-6 in adult sepsis published on CNKI, Wanfang Data, PubMed, Embase, Cochrane Library, and Web of Science were searched up to December 2023. QUADAS-2 scale was used to evaluate the quality of the included literature. Stata 15.0 statistical software was used for data processing. The pooled sensitivity, specificity, diagnostic odds ratio (DOR), positive likelihood ratio (PLR), and negative likelihood ratio (NLR) were calculated. The summary receiver operating characteristic curve (SROC) was drawn, with the area under the curve (AUC) calculated.</p><p><strong>Evidence synthesis: </strong>A total of 31 articles were included in this meta-analysis. The results of the meta-analysis showed that the combined sensitivity, specificity, DOR, PLR, and NLR of circulating IL-6 for the diagnosis of adult sepsis were 0.74 (95%CI: 0.69-0.78), 0.73 (95%CI: 0.68-0.78), 7.71 (95%CI: 5.66-10.52), 2.77 (95%CI: 2.29-3.35), 0.36 (95%CI: 0.30-0.43), respectively. The AUC was 0.80 (95%CI: 0.76-0.83).</p><p><strong>Conclusions: </strong>Circulating IL-6 has a good diagnostic value in adult sepsis, with moderate sensitivity and specificity. Therefore, IL-6 can provide a basis for the diagnosis of adult sepsis.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"90 11","pages":"1041-1050"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva anestesiologicaPub Date : 2024-11-01Epub Date: 2024-07-09DOI: 10.23736/S0375-9393.24.18273-9
Tetsuro Kimura
{"title":"A novel technique to exchange tracheal tubes using an Aintree Intubation CatheterTM over an airway exchange catheter.","authors":"Tetsuro Kimura","doi":"10.23736/S0375-9393.24.18273-9","DOIUrl":"10.23736/S0375-9393.24.18273-9","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"1057-1058"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141559116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva anestesiologicaPub Date : 2024-11-01Epub Date: 2024-07-25DOI: 10.23736/S0375-9393.24.18288-0
Franca Benini, Rossana Berardi, Laura Bogliolo, Fabio Borrometi, Francesco Cellini, Leonardo Consoletti, Gabriele Finco, Diego Fornasari, Marta Gentili, Gino Gobber, Pierangelo Lora Aprile, Ernesto Maranzano, Franco Marinangeli, Paola Miglioranzi, Alessia Violini
{"title":"The need for consistent epidemiological data on chronic pain in Italy and beyond.","authors":"Franca Benini, Rossana Berardi, Laura Bogliolo, Fabio Borrometi, Francesco Cellini, Leonardo Consoletti, Gabriele Finco, Diego Fornasari, Marta Gentili, Gino Gobber, Pierangelo Lora Aprile, Ernesto Maranzano, Franco Marinangeli, Paola Miglioranzi, Alessia Violini","doi":"10.23736/S0375-9393.24.18288-0","DOIUrl":"10.23736/S0375-9393.24.18288-0","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"1060-1062"},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Highlights of the November 2024 issue.","authors":"Franco Cavaliere","doi":"10.23736/S0375-9393.24.18635-X","DOIUrl":"https://doi.org/10.23736/S0375-9393.24.18635-X","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"90 11","pages":"951-953"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guilherme H Ortegal, Eduardo C Barbosa, Pedro C Faria, João V Couto, Guilherme C Silva, Márcio H Souza, Lucas N Ferreira, Vitor R Moraes, Maria C Campos, Luiza A Campos
{"title":"Ciprofol versus propofol for adult sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis.","authors":"Guilherme H Ortegal, Eduardo C Barbosa, Pedro C Faria, João V Couto, Guilherme C Silva, Márcio H Souza, Lucas N Ferreira, Vitor R Moraes, Maria C Campos, Luiza A Campos","doi":"10.23736/S0375-9393.24.18203-X","DOIUrl":"10.23736/S0375-9393.24.18203-X","url":null,"abstract":"<p><strong>Introduction: </strong>Although propofol is widely preferred as a sedative agent in gastrointestinal endoscopy, its use is commonly associated with hemodynamic adverse events. New sedatives, such as ciprofol, are emerging with promising results. Thus, we aimed to perform a systematic review and meta-analysis to compare efficacy-, safety-, and satisfaction-related outcomes between ciprofol and propofol for adult sedation in gastrointestinal endoscopy.</p><p><strong>Evidence acquisition: </strong>We systematically searched MEDLINE, Embase, and Cochrane databases for randomized controlled trials comparing sedation with ciprofol vs. propofol in adult patients undergoing gastrointestinal endoscopy. Risk ratios (RRs) and mean differences (MDs) with their 95% confidence intervals (95% CIs) were employed for dichotomous and continuous outcomes, respectively, using a random-effects model. We conducted all statistical analyses using R software (version 4.2.1).</p><p><strong>Evidence synthesis: </strong>We included six trials (1225 patients). The ciprofol group had a significantly lower risk of respiratory depression (RR 0.47; 95% CI 0.31, 0.71) and injection pain (RR 0.09; 95% CI 0.04, 0.20) compared with the propofol group, while there were no significant differences in other adverse events between both drugs. There were no significant differences between both groups in time-related outcomes, as well as in the probability of procedure success (RR 1.01; 95% CI 0.99, 1.03). Additionally, ciprofol provided a significantly higher patient satisfaction compared with propofol (MD 0.19; 95% CI 0.08, 0.31).</p><p><strong>Conclusions: </strong>This systematic review and meta-analysis demonstrated similar clinical efficacy and better safety profile of ciprofol compared with propofol for adult sedation in gastrointestinal endoscopies. Furthermore, patient satisfaction scores were higher with ciprofol.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"90 11","pages":"1013-1021"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}