Minerva anestesiologica最新文献

{"title":"Time to collect informed consent to participate to randomized control trials in Intensive Care Unit patients: a single-center retrospective study over 7 years.","authors":"Fabien Coisy, Benoit Barbier, Loubna Elotmani, Myriam Mezzarobba, Shreeja Tripathi, Audrey Ambert, Edouard Wacheux, Càtia Meirinhos Aparicio, Jerome Maillot, Christophe Masseguin, Jean-Yves Lefrant, Philippe Cuvillon, Yann Gricourt, Nicolas Boulet, Mircea T Sofonea","doi":"10.23736/S0375-9393.26.19815-0","DOIUrl":"10.23736/S0375-9393.26.19815-0","url":null,"abstract":"<p><strong>Background: </strong>This retrospective study analyzed the time interval to obtain patient consent for participation in 14 randomized clinical trials (RCTs)(505 patients) across three French Intensive Care Units.</p><p><strong>Methods: </strong>The following time intervals (median values and interquartile ranges [IQR]) were measured: from patient consent to inclusion; from relative consent to inclusion; from inclusion to patient consent (initial relative consent); from emergency procedure inclusion to direct final patient consent; from emergency procedure to relative consent; and from relative consent to final patient consent. The distribution of the time to first consent was modelled using maximum likelihood parameter estimation of a zero-inflated log-normal distribution accounting for right-censoring.</p><p><strong>Results: </strong>Pre-inclusion consents were obtained from 106 (21.0%) patients and from 36 (7.1%) patient relatives (with deferred patient consent in 21 patients (4.2%) (median time = 12 [5-29] days), and no deferred consent in 15 patients [3.0%]). Emergency procedure was necessary in 363 patients (71.9%): 147 patients (29.1%) gave deferred consent directly (median time = 4 [2-9] days). In 156 patients (30.9%), relatives gave initial consent (median time: 3 [1-7] days), with subsequent 60 patient consents (11.9%) (median time = 19 [7-51] days). No further patient consent was obtained in 96 cases (19%). Additionally, in 60 patients (11.9%), neither patient nor relative consent could be secured.</p><p><strong>Conclusions: </strong>Emergency procedure was the predominant method of patient enrolment (71.9%) in RCTs. The median time to obtain patient consent ranged from 0 to 19 days. A final consent could not be obtained in 33.9% patients.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"858-867"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shock-press: an Italian national survey investigating the use of vasopressors in cardiac patients experiencing cardio-circulatory shock.","authors":"Antonio Giorgi, Ferdinando Delor, Calogero Blanda, Andrea Crosignani, Giovanna Landi, Fabio Sangalli, Sabino Scolletta, Simona Silvetti, Massimo Baiocchi, Fabrizio Monaco, Alessandro Marzio, Valentina Ajello, Tommaso Aloisio, Marco Ranucci, Cristina Santonocito, Michele Mondino, Gianluca Paternoster, Paolo Meani","doi":"10.23736/S0375-9393.26.19838-1","DOIUrl":"10.23736/S0375-9393.26.19838-1","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"915-917"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided recto-intercostal fascial plane block with continuous catheter placement for multimodal analgesia after laparoscopic subtotal gastrectomy.","authors":"Mehmet G Taflan, Suna Kara Gormus, Elif Sarikaya Özel, Hatice Kusderci, Emre C Soydan","doi":"10.23736/S0375-9393.26.19984-2","DOIUrl":"10.23736/S0375-9393.26.19984-2","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"928-931"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is informed consent in the critically ill informed?","authors":"Arieh Eden, Charles L Sprung","doi":"10.23736/S0375-9393.26.20232-8","DOIUrl":"10.23736/S0375-9393.26.20232-8","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"796-797"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of doppler renal resistive index in early detection of postoperative acute kidney injury in prolonged cardiopulmonary bypass cardiac surgeries.","authors":"Musa H Uçar, Canan Yilmaz, Filiz Ata, Derya Karasu, Şule Balk Uçar, Aycan Kurtarangil Doğan, Nurcan K Kat, Mehmet Gamli","doi":"10.23736/S0375-9393.26.19699-0","DOIUrl":"10.23736/S0375-9393.26.19699-0","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study is to investigate the value of renal Doppler ultrasonography-derived Renal Resistive Index (RRI) for early prediction of cardiac surgery-associated acute kidney injury (CSA-AKI) in patients undergoing prolonged cardiopulmonary bypass (CPB) and aortic cross-clamp (ACC) times, and to assess perioperative risk factors, length of stay, and short-term outcomes.</p><p><strong>Methods: </strong>Ninety adult patients (>18 years) scheduled for elective cardiac surgery under general anesthesia, with CPB >70 minutes and ACC >60 minutes, without preexisting acute or chronic renal failure. Patients were stratified according to KDIGO criteria as Group 1 (no CSA-AKI, N.=64) and Group 2 (CSA-AKI, N.=26). Preoperative and postoperative (first hour) RRI measurements were performed by a single radiologist. Demographic, intraoperative, and postoperative parameters including transfusion, urine output, fluid balance, vasoactive/inotropic agent and diuretic use, serum creatinine, and hematocrit levels were collected.</p><p><strong>Results: </strong>The postoperative RRI cutoff of 0.70 predicted CSA-AKI with 76.9% sensitivity and 73.4% specificity (P<0.001). Group 2 had significantly lower hematocrit levels during CPB rewarming (P=0.04). On postoperative days 2 and 3, urine output and fluid balance differed significantly between groups (P: 0.004-0.005 and P<0.001 - P<0.001, respectively). Inotropic/vasopressor requirements were higher in Group 2 on day 3 (P=0.003). Stage 1 AKI was most common (80.8%), predominantly on postoperative day 2. Group 2 demonstrated longer mechanical ventilation, prolonged ICU stay, and higher 30-day mortality (P=0.016, P=0.012, and P=0.006).</p><p><strong>Conclusions: </strong>Routine postoperative assessment of RRI in high-risk cardiac surgeries may enable earlier detection of CSA-AKI compared with KDIGO criteria, allowing earlier initiation of renal-protective strategies and potentially improving patient outcomes.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"832-844"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147776092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of intraoperative transcutaneous electrical acupoint stimulation in patients undergoing hip arthroplasty or femur fracture fixation under general anesthesia.","authors":"Zhen Lei, Jingjing Yang, Li Ye, Linzhi Xia, Wenxiu Li, Xugui Li","doi":"10.23736/S0375-9393.26.19740-5","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.19740-5","url":null,"abstract":"<p><strong>Background: </strong>This study assesses the efficacy of transcutaneous electrical acupoint stimulation (TEAS) -assisted general anesthesia in orthopedic surgeries, focusing on perioperative parameters, hemodynamics, biochemical responses, pain, cognitive function, adverse reactions, and patient satisfaction.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted with 217 patients who underwent hip replacement surgery or femoral fracture fixation under general anesthesia at the Affiliated Hospital of Wuhan Sports University from August 2021 to August 2023. Patients were divided into two groups: the control group (N.=111) receiving conventional general anesthesia and the TEAS group (N.=106) receiving TEAS-assisted general anesthesia. Data collected included hemodynamic parameters, biochemical markers (cortisol, endothelin, alanine transaminase, aspartate transaminase, and serum creatinine levels), Visual Analogue Scale (VAS) for pain, Mini-Mental State Examination (MMSE) for cognitive function, incidence of adverse reactions, and postoperative satisfaction.</p><p><strong>Results: </strong>The TEAS group showed significantly lower intraoperative medication use (propofol, remifentanil, and sufentanil) and fewer rescue analgesia requirements (P<0.001). Postoperative VAS scores were lower at all time points (P<0.001), and MMSE scores indicated better early postoperative cognitive function (P<0.001). TEAS correlated with reduced hemodynamic fluctuations, lower heart rates, and stable mean arterial pressures (P<0.05). Biochemical responses were favorable, with lower cortisol and endothelin levels (P<0.05). The incidence of adverse reactions was lower (P=0.033), and patient satisfaction was higher (P=0.004) in the TEAS group.</p><p><strong>Conclusions: </strong>TEAS-assisted general anesthesia significantly improves perioperative outcomes in orthopedic surgery patients by enhancing hemodynamic stability, reducing medication needs, mitigating stress responses, decreasing pain, and preserving cognitive function, while increasing satisfaction and lowering adverse reactions. Further prospective studies are needed to validate these findings.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"92 9","pages":"817-831"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highlights from the September 2026 issue.","authors":"Franco Cavaliere","doi":"10.23736/S0375-9393.26.20572-2","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20572-2","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"92 9","pages":"787-789"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute meralgia paresthetica during labor: diagnostic and therapeutic lateral femoral cutaneous nerve block.","authors":"Paula Gil-Esteller, Roger Queralt, Eva M Sola, Carles Espinós","doi":"10.23736/S0375-9393.26.20016-0","DOIUrl":"10.23736/S0375-9393.26.20016-0","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"935-936"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) for postoperative analgesia in an infant undergoing open pyeloplasty.","authors":"Volkan Özen, Engin I Turan, Selçuk Alver, Doğakan Yiğit, Kübra Demir, Bahadir Çiftçi","doi":"10.23736/S0375-9393.26.19976-3","DOIUrl":"10.23736/S0375-9393.26.19976-3","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"925-927"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From image to insight: why videolaryngoscopy needs its own language.","authors":"Manuel Á Gómez-Ríos, Alfredo Abad-Gurumeta","doi":"10.23736/S0375-9393.26.19896-4","DOIUrl":"10.23736/S0375-9393.26.19896-4","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"790-792"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}