{"title":"Pregabalin for sleep quality and postoperative pain: a potential strategy for long-term recovery.","authors":"Wen-Yi Lai, Ching-Wei Chuang","doi":"10.23736/S0375-9393.25.18964-5","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18964-5","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Engin I Turan, Volkan Özen, Duygu Gürel, Ayça S Şahin
{"title":"Efficacy of modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) for analgesia in a pediatric patient operated for hydatid cyst.","authors":"Engin I Turan, Volkan Özen, Duygu Gürel, Ayça S Şahin","doi":"10.23736/S0375-9393.25.18891-3","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18891-3","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative evaluation of glottis and trachea using mixed reality technology in neurosurgical patients.","authors":"Balaji Vaithialingam, Satish Rudrappa","doi":"10.23736/S0375-9393.25.18852-4","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18852-4","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Engin I Turan, Salih Karabelli, Abdurrahman E Baydemir, Ayça S Şahin
{"title":"Evaluation of the serratus posterior superior intercostal plane block for postoperative analgesia in posterior cervical stabilization surgery.","authors":"Engin I Turan, Salih Karabelli, Abdurrahman E Baydemir, Ayça S Şahin","doi":"10.23736/S0375-9393.25.18798-1","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18798-1","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva anestesiologicaPub Date : 2025-03-01Epub Date: 2024-11-04DOI: 10.23736/S0375-9393.24.18506-9
Engin I Turan, Abdurrahman E Baydemir, Ayça S Şahin
{"title":"Efficacy of the quadro-iliac plane block in postoperative pain management for proximal femoral nail surgeries.","authors":"Engin I Turan, Abdurrahman E Baydemir, Ayça S Şahin","doi":"10.23736/S0375-9393.24.18506-9","DOIUrl":"10.23736/S0375-9393.24.18506-9","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"221-223"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Irrational refusal of medical treatment: ethical considerations.","authors":"Enrico Furlan, Alberto Giannini","doi":"10.23736/S0375-9393.25.18656-2","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18656-2","url":null,"abstract":"<p><p>This paper examines the ethical issues surrounding a specific case of patient refusal of medical treatment: refusal stemming from irrational beliefs or misinformation. While respecting patient autonomy is a foundational principle of contemporary medical ethics, its application becomes challenging when patients reject life-saving treatments based on irrational beliefs (e.g., conspiracy theories, as seen during the COVID-19 pandemic). This situation creates a paradox: the doctrine of informed consent and dissent, while designed to protect conscious and autonomous choices, can also enable misinformed, irrational decisions. Upon distinguishing three kinds of treatment refusal (rational, non-rational, and irrational), the paper clarifies why the moral distress experienced by healthcare professionals when dealing with irrational refusals is justified and reflects a proper moral disposition. It argues that immediate acceptance of such refusals reflects a shallow understanding of both patient autonomy and the doctor-patient relationship. Furthermore, the paper advocates for a deliberative model, wherein physicians are morally obliged to engage patients in thoughtful dialogue and attempt to persuade them - within available time constraints. Attempts to persuade patients are not forms of disguised paternalism, nor are they primarily inspired by the principle of beneficence. On the contrary, such attempts derive from a proper understanding of autonomy: physicians respect their patients as moral agents by engaging them in frank exchanges, thus creating the conditions for more authentic autonomous choices.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"91 3","pages":"214-219"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of estazolam plus remimazolam on attenuating preoperative anxiety and remifentanil-induced postoperative hyperalgesia in elective gynecological laparoscopic surgery: a randomized clinical trial.","authors":"Yu Huang, Rui-Jia Gao, Shi-Meng Mao, Jin-Liang Yao, Hong-Yan He, Ying Wang, Ji-Ying Feng","doi":"10.23736/S0375-9393.24.18563-X","DOIUrl":"10.23736/S0375-9393.24.18563-X","url":null,"abstract":"<p><strong>Background: </strong>Preoperative anxiety is closely related to opioid-induced hyperalgesia, and high levels of preoperative anxiety have the potential to aggravate opioid-induced hyperalgesia. We aimed to estimate the effect of estazolam, remimazolam, and their combination on preoperative anxiety and opioid-induced hyperalgesia in patients undergoing elective gynecological laparoscopic surgery.</p><p><strong>Methods: </strong>We carried out a randomized, double-blind, placebo-controlled experiment between October 2020 and April 2021. Starting on 9, October 2020,a total of 108 patients were split into four groups: (1 mg estazolam or starch was taken orally on the evening before surgery; 0.1 mg/kg remimazolam or normal saline was administered intravenously after entering the operating room) Group E received estazolam and normal saline; Group R received starch and remimazolam; participants in Group ER were given not only estazolam but also remimazolam; participants in Group C were given starch and normal saline. We recorded pain intensity at rest at 24 hours postoperatively as the primary outcome and measured pain intensity, sufentanil consumption, and adverse events within 72 hours postoperatively.</p><p><strong>Results: </strong>The mean anxiety scores were significantly lower in Groups E, R, and ER than in Group C before surgery. Compared with Group C, mean pain scores were significantly lower in Group ER at 0.5, 1, 4, 8, 24, 48, and 72 hours after surgery and lower in Groups R or E at 4, 8, and 24 hours after surgery. The mean pain scores in Group E (at 8 and 24 hours postoperatively) and Group R (at 8 hours postoperatively) were both significantly higher than those in Group ER. Moreover, the mean cumulative sufentanil consumption was significantly lower in Group ER at 0.5, 1, 4, 8, 24, 48, and 72 hours after surgery and lower in Groups E or R at 0.5 hours after surgery, compared with Group C.</p><p><strong>Conclusions: </strong>The preoperative application of estazolam, remimazolam, and their combination can relieve preoperative anxiety and postoperative pain for patients undergoing gynecological laparoscopic surgery. Moreover, the preoperative combination can also significantly reduce postoperative sufentanil consumption.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":"164-175"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of high vs. low perioperative inspired oxygen fraction on length of hospital stay and postoperative complications: a systematic review, meta-analysis, and trial sequential analysis.","authors":"Mimi Wu, Lanlan Chang, Leying Sun, Zhao Dai, Jinhua Bo, Xin Xu","doi":"10.23736/S0375-9393.25.18649-5","DOIUrl":"https://doi.org/10.23736/S0375-9393.25.18649-5","url":null,"abstract":"<p><strong>Introduction: </strong>Prolonged length of hospital stay (LOS) and postoperative complications in surgical patients are major public health issues worldwide. Perioperative hyperoxia may increase LOS, and the incidence of cardiac, cerebral, renal, and pulmonary injury; however, the supporting clinical evidence is controversial. Therefore, the current meta-analysis included all relevant randomized controlled trials (RCTs) to investigate the effect of high and low inspired oxygen fraction (FiO<inf>2</inf>) on LOS, according to postoperative complications.</p><p><strong>Evidence acquisition: </strong>Standard published RCTs were searched from bibliographic databases to identify all evidence reporting perioperative FiO<inf>2</inf> for patients undergoing surgeries. The primary outcome was LOS, and the secondary outcomes were postoperative organ complications, surgical site infection (SSI), and postoperative mortality. The relative risk (RR) and Peto-odds ratio (Peto-OR) for dichotomous outcomes and the mean difference (MD) and standardized mean difference (SMD) for continuous outcomes were estimated using a random-effects model. Trial sequential analysis (TSA) was performed in the meta-analysis to evaluate the required information sizes and assess whether the primary outcome in our meta-analysis was conclusive.</p><p><strong>Evidence synthesis: </strong>Thirty-one RCTs with 10506 participants undergoing different surgeries were included. The LOS in the high FiO<inf>2</inf> group did not differ significantly from that in the low FiO<inf>2</inf> group (MD -0.01, 95% CI -0.10 to 0.08, P=0.81). Moreover, we found no meaningful evidence of subgroup differences in the primary outcome, in comparisons of FiO<inf>2</inf>, RCT type, surgery type, duration of oxygen inhalation or timing of oxygen inhalation. TSA results further suggested that the number of included studies was sufficient for the primary outcome. There was also no significant difference in postoperative organ complications (cardiac, cerebral, renal, and pulmonary), SSI (rate of SSI, ASEPSIS score, and ASEPSIS score > 20 cases), or postoperative mortality. For postoperative atelectasis, sensitivity analysis showed that after exclusion of one study, \"Myles 2007,\" high FiO<inf>2</inf> was associated with increased postoperative atelectasis.</p><p><strong>Conclusions: </strong>The use of low FiO<inf>2</inf> has no effect on LOS, or the incidence of cardiac, cerebral, and renal injury or postoperative mortality. Compared with low FiO<inf>2</inf>, high FiO<inf>2</inf> did not reduce SSI which was contrary to the guidelines. Meanwhile, high FiO<inf>2</inf> may increase postoperative atelectasis in surgical patients.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":"91 3","pages":"201-213"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}