{"title":"Residual gastric content after tirzepatide discontinuation: is one week enough?","authors":"Ela E Hidiroglu, Savas Altinsoy","doi":"10.23736/S0375-9393.26.20145-1","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20145-1","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is it feasible to reduce serious complications in regional anesthesia?","authors":"Germano DE Cosmo, Laura Levantesi","doi":"10.23736/S0375-9393.26.20229-8","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20229-8","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selcuk Alver, Volkan Ozen, Mehmet I Büget, Ertan Emek, Halil Erbis, Nadi N Oztürk, Bahadir Ciftci
{"title":"Dual block strategy for complex incision in pediatric kidney transplantation: M-TAPA and quadroiliac plane block combination.","authors":"Selcuk Alver, Volkan Ozen, Mehmet I Büget, Ertan Emek, Halil Erbis, Nadi N Oztürk, Bahadir Ciftci","doi":"10.23736/S0375-9393.26.20343-7","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20343-7","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence in health: small step for machines, giant leap for mankind.","authors":"Gerhardus J Kuiper, Fabian H Tijssen","doi":"10.23736/S0375-9393.26.20258-4","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20258-4","url":null,"abstract":"","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient blood management in cardiac valve surgery: combined effects of preoperative hemoglobin optimization and intraoperative blood conservation.","authors":"Esther Méndez, Jorge Vallés, Ángel Candela, Guillermo Puig, Misericòrdia Basora, Maria J Colomina","doi":"10.23736/S0375-9393.26.19940-4","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.19940-4","url":null,"abstract":"<p><strong>Background: </strong>Transfusion practices in cardiac valve surgery remain variable despite evidence supporting integrated patient blood management strategies. This study evaluated the independent and combined effects of preoperative hemoglobin status and intraoperative blood conservation techniques on transfusion requirements in elective open cardiac valve surgery.</p><p><strong>Methods: </strong>We conducted a nationwide retrospective multicenter cohort study using data from the national Maturity Assessment Model for Patient Blood Management registry. Adult patients undergoing elective open cardiac valve surgery between 2016 and 2022 in 23 Spanish hospitals were included. Anemia was defined as preoperative hemoglobin <13 g/dL, irrespective of sex. The primary outcome was red blood cell transfusion during the index hospital admission.</p><p><strong>Results: </strong>A total of 9889 patients were analyzed, with an overall transfusion rate of 53%. Anemic patients (37.3%) had higher transfusion rates than non-anemic patients (70.2% vs. 42.7%). In a separate model restricted to 5763 patients with intraoperative data, combined use of tranexamic acid and intraoperative cell salvage was associated with lower transfusion risk compared with no blood conservation strategy (47.7% vs. 52.3%; adjusted odds ratio 0.83; 95% confidence interval 0.71-0.97), whereas use of either strategy alone showed no meaningful transfusion reduction. When preoperative hemoglobin status and intraoperative strategies were analyzed jointly, the lowest transfusion rate (37.6%) occurred in non-anemic patients receiving both strategies, whereas anemic patients without blood conservation had the highest rate (74.9%; adjusted odds ratio 4.95; 95% confidence interval 4.10-5.97).</p><p><strong>Conclusions: </strong>Combined implementation of adequate preoperative hemoglobin levels and intraoperative blood conservation strategies was associated with lower transfusion rates in elective cardiac valve surgery, supporting the value of integrated perioperative patient blood management pathways in real-world practice.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burhan Dost, Yunus E Karapinar, Esra Turunc, Engin I Turan, Muzeyyen Beldagli, Madan Narayanan, Alessandro DE Cassai
{"title":"Wide-awake local anesthesia no tourniquet (WALANT) versus brachial plexus block for upper extremity surgery: a systematic review and meta-analysis.","authors":"Burhan Dost, Yunus E Karapinar, Esra Turunc, Engin I Turan, Muzeyyen Beldagli, Madan Narayanan, Alessandro DE Cassai","doi":"10.23736/S0375-9393.26.20029-9","DOIUrl":"https://doi.org/10.23736/S0375-9393.26.20029-9","url":null,"abstract":"<p><strong>Background: </strong>Wide-awake local anesthesia no tourniquet (WALANT) has increasingly been used as an alternative to brachial plexus block (BPB) for upper extremity surgery; however, comparative evidence regarding analgesic efficacy, recovery outcomes, and patient satisfaction remains inconsistent. This systematic review and meta-analysis aimed to compare WALANT with BPB in upper extremity surgery, with intraoperative pain prespecified as the primary outcome.</p><p><strong>Methods: </strong>A systematic search of PubMed, Embase, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials was conducted from inception to January 1<sup>st</sup>, 2026. Comparative randomized and non-randomized studies evaluating WALANT versus BPB in adult patients undergoing upper extremity surgery were included. Risk of bias was assessed using RoB 2 and ROBINS-I tools, and certainty of evidence was evaluated using the GRADE approach.</p><p><strong>Results: </strong>Fifteen studies involving 940 patients met the inclusion criteria. There was no significant difference in intraoperative pain between WALANT and BPB (MD 1.11, 95% CI -2.54 to 4.76). Postoperative pain scores were similar during the early postoperative period (0-2 h) and at 24 h; however, WALANT was associated with lower pain scores between 2 and 8 h postoperatively (MD -1.39, 95% CI -2.58 to -0.19). WALANT was also associated with a shorter length of hospital stay (MD -10.81 h, 95% CI -18.49 to -3.13). No significant differences were observed in complication rates, need for additional anesthesia or analgesia, or patient satisfaction. The certainty of evidence for key outcomes was rated as very low, primarily due to risk of bias, substantial heterogeneity, and imprecision.</p><p><strong>Conclusions: </strong>Based on very low-certainty evidence, WALANT appears to provide analgesic outcomes broadly comparable to BPB in upper extremity surgery and may be associated with shorter hospital stay. These findings should be interpreted cautiously and primarily considered hypothesis-generating, highlighting the need for well-designed randomized trials.</p>","PeriodicalId":18522,"journal":{"name":"Minerva anestesiologica","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148278056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}