{"title":"Applications of paper spray ionization mass spectrometry in forensic science: A mini review.","authors":"Sachil Kumar, Tulsidas R Baggi","doi":"10.1177/00258024251363088","DOIUrl":"10.1177/00258024251363088","url":null,"abstract":"<p><p>Paper spray ionization (PSI) has emerged as a key ambient ionization technique in microanalysis over the past decade, valued for its ease of use and minimal sample preparation. This study reviews PSI's applications in forensic science, covering areas such as biomolecules, drugs of abuse, inks, explosives, toxicology, and trace evidence. To achieve these objectives, electronic searches were performed across several databases-Scopus, Web of Science, Science Direct, and PubMed-covering publications from 2010 through December 2023, with a focus on English-language articles. This search strategy yielded 40 relevant studies, which were reviewed to assess PSI-MS's current capabilities and advancements. The review underscores Paper Spray Ionization Mass Spectrometry's (PSI-MS) versatility, particularly its compatibility with various sampling methods like dried blood spots, which enhances its utility for rapid point-of-care (POC) analysis. This capability facilitates the efficient analysis of biochemical and forensic samples while bypassing lengthy separation procedures, marking a significant advancement in forensic analysis techniques.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"130-141"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144794890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep learning-based CNN model for multiclass classification of fingerprint patterns.","authors":"Apurav Mahajan, Damini Siwan, Peehul Krishan, Akansha Rana, Ritika Verma, Ankita Guleria, Rakesh Meena, Nandini Chitara, Ayushi Srivastava, Kewal Krishan","doi":"10.1177/00258024251355042","DOIUrl":"10.1177/00258024251355042","url":null,"abstract":"<p><p>Fingerprints are widely used as biometric parameters for identification purposes because of their uniqueness. Moreover, many digital devices have employed fingerprints for security purposes throughout the world. An automatic artificial intelligence-based classification system can reduce the time spent running through the database for fingerprint matching by arranging fingerprints into disjoint classes. It can also help classify fingerprints at the crime scene easily and quickly. The present study proposed a convolutional neural network (CNN) model for the multiclass classification of fingerprint patterns (Arches, Loops, Whorls, and Composites) according to Henry's classification. The model was trained on 2000 fingerprint patterns collected from the fingers of 200 participants. The dataset was split into train, test, and validation part with the ratio of 8:1:1, respectively. The presented CNN model was evaluated by using a confusion matrix for the testing process. Training, validating, and testing the accuracy of the CNN model for classifying fingerprint datasets into four main classes were 89%, 84%, and 85.5%, respectively. This model shows its application as an aiding tool for fingerprint analysis in crime scene investigation, forensic examinations, and fingerprint research.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"114-121"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AI in the criminal justice system: From 'AI ethics' to 'hermeneutic risk'.","authors":"Karen McGregor Richmond, Charlotte Primeau","doi":"10.1177/00258024251407531","DOIUrl":"10.1177/00258024251407531","url":null,"abstract":"","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"75-79"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145810320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The shape of justice: Sentencing of mentally ill defendants convicted of manslaughter.","authors":"Tim Exworthy","doi":"10.1177/00258024251380965","DOIUrl":"10.1177/00258024251380965","url":null,"abstract":"<p><p>In June 2023, a mentally ill man stabbed to death three people in the street and seriously injured three others. A plea of guilty to manslaughter on the grounds of diminished responsibility (DR) was accepted by the Crown Prosecution Service and he subsequently received a restricted hospital order (sections 37 & 41) under the Mental Health Act 1983. There has been considerable public discussion around this case. This paper sets out the background to the partial defence to murder of DR as well as the current approach to the sentencing of mentally ill defendants convicted of manslaughter. The Court of Criminal Appeal later considered a referral that the sentence had been 'unduly lenient'. The court considered the legal factors of the degree of retained responsibility and the extent to which a penal element should be reflected in the sentence. From the psychiatric perspective, the release regimes of the two options of a restricted hospital order or a hybrid order were also examined by the Court, as these related directly to protection of the public.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"168-173"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145176452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ken Inoue, Sultana Razia, Haruo Takeshita, Tatsushige Fukunaga
{"title":"Urgent need for suicide prevention among females: Analysis of suicide statistics from 47 prefectures nationwide in Japan.","authors":"Ken Inoue, Sultana Razia, Haruo Takeshita, Tatsushige Fukunaga","doi":"10.1177/00258024251363097","DOIUrl":"10.1177/00258024251363097","url":null,"abstract":"","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"180-181"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Donato, Douglas H Ubelaker, Luigi Tonino Marsella, Marcela Lerda, Michele Treglia, Margherita Pallocci, Anna Laurathe Santunione, Jessika Camatti, Rossana Cecchi
{"title":"The age progression technique to support Missing Children Argentina: A case report.","authors":"Laura Donato, Douglas H Ubelaker, Luigi Tonino Marsella, Marcela Lerda, Michele Treglia, Margherita Pallocci, Anna Laurathe Santunione, Jessika Camatti, Rossana Cecchi","doi":"10.1177/00258024251380953","DOIUrl":"10.1177/00258024251380953","url":null,"abstract":"<p><p>The phenomenon of missing persons draws the attention of authorities, who implement measures to address the issue. Missing Children Argentina (MCA) is a non-profit organization that supports the families of missing individuals in Argentina. MCA receives support with age progression techniques from the Italian non-profit organization Italian Missing Children (IMC). MCA and IMC have been collaborating since 2020, processing nine cases of digital aging. This paper presents the case of a missing girl, and her age progression is reported as an example to document the collaborative work between the two organizations. The age progression technique, performed due to photographs of the missing person's relatives, is based on scientific standards of facial aging. Through the use of Adobe Photoshop (2022<sup>®</sup>), specific facial morphological features were identified in high-resolution reference photos and combined to create an updated image of the missing individual. The digitally aged image is then included in a poster and shared on social media. The poster includes the time and place of the disappearance, personal details of the missing person, contact information for potential sightings, original photos taken closest to the time of disappearance, and the digitally age-progressed images. It is crucial to inform the public about the possibility of requesting age progression for long-term missing persons. This technique can update the appearance of the individual and significantly support search efforts.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"174-179"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Greta Seveso, Mateus Eduardo Romão, Serena Barello, Silvia Damiana Visonà, Giovanni Cecchetto, Giacomo Belli
{"title":"Medically assisted suicide in Italy after regional law No. 16/2025: Perspectives, challenges, and the need for psychological support and specialized training for healthcare professionals.","authors":"Greta Seveso, Mateus Eduardo Romão, Serena Barello, Silvia Damiana Visonà, Giovanni Cecchetto, Giacomo Belli","doi":"10.1177/00258024251380962","DOIUrl":"10.1177/00258024251380962","url":null,"abstract":"<p><p>On 11 February 2025, Tuscany became the first region in Italy to approve a law regulating medically assisted suicide. However, the law makes no provision for psychological support or educational and training programs for healthcare professionals involved in the procedure. Studies from countries where assisted suicide has long been legal highlight its significant psychological and emotional impact on care providers. In response, various forms of psychological support have been implemented to help and protect healthcare staff from the side effects of these events. Moreover, specialized training programs have been developed to equip healthcare providers with the necessary skills to handle assisted suicide requests appropriately. Tuscany's initiative may pave the way for other regions to adopt similar measures and, ideally, for a parliamentary law to regulate the practice nationwide. Therefore, this paper strongly argues that the inclusion of structured psychological support and specialized training programs is a fundamental requirement for developing an ethical, sustainable, and comprehensive end-of-life framework in Italy.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"160-167"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessika Camatti, Anna Laura Santunione, Silvia Ciuffreda, Erjon Radheshi, Francesco Saverio Romolo, Rossana Cecchi
{"title":"Updates on medically assisted suicide in Italy: Approval of first regional law in February 2025.","authors":"Jessika Camatti, Anna Laura Santunione, Silvia Ciuffreda, Erjon Radheshi, Francesco Saverio Romolo, Rossana Cecchi","doi":"10.1177/00258024251362541","DOIUrl":"10.1177/00258024251362541","url":null,"abstract":"<p><p>In Italy, the issue of medically assisted suicide is addressed by the sentence number 242 of the Constitutional Court (22<sup>nd</sup> November 2019). Further indications of organisational nature are needed, which are under the responsibility of the Italian Parliament and each regional health administration. Recently, the sentence number 135 of the Constitutional Court (1<sup>st</sup> July 2024) has provided further specifications regarding '<i>life-support treatment'</i>, which still remains controversial. Regional differences in Italy regarding medically assisted suicide are reported in this article, showing that, on the date of 11<sup>th</sup> February 2025, Tuscany is the first and only Italian region to have passed a regional law on medically assisted suicide. One possible approach to discussion and management of this sensitive and controversial issue could be cooperative forms of regionalism while waiting for a national law. To date, after the first Italian case, which refers to Marche region and occurred on 16<sup>th</sup> June 2022 (Federico Carboni, also known as 'Mario'), four more individuals in Italy have resorted to medically assisted suicide: 'Gloria' in Veneto, 'Anna' in Friuli-Venezia Giulia, a man in Emilia Romagna, and 'Vittoria' in Veneto. It is hoped that a national law will be approved soon, as strongly urged by the Constitutional Court; if not, efforts should be made to identify and implement shared and standardised procedures throughout the Italian territory, encouraging cooperative forms of regionalism. This would allow patients to know that the request is followed by unambiguous responses from the authorities, within a reasonable time.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"107-113"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visual analysis of hotspots and evolutionary trends in the field of postmortem interval estimation.","authors":"Chengqiang Du, Yehui Lv","doi":"10.1177/00258024251348722","DOIUrl":"10.1177/00258024251348722","url":null,"abstract":"<p><p><b>Purpose:</b> Through a visual analysis of the literature on postmortem interval estimation research collected in the Web of Science database, this study aims to explore the development process, research hotspots, and technical approaches in this field, providing a reference for scholars and professionals in related fields. <b>Methods:</b> It retrieves English-language articles related to postmortem interval estimation published in the Web of Science Core Collection from its inception until December 31, 2023, that meet the inclusion criteria. The study calculates the annual number of publications and citations and analyzes the trends. Based on these annual publication volumes, a second search is conducted for the period during which the number of publications in this field exceeded 100 per year, specifically from January 1, 2014, to December 31, 2023. CiteSpace 6.2.R4 software is used to perform a visual analysis of the second set of retrieved documents. <b>Results:</b> The first search retrieved 1778 articles related to postmortem interval estimation research. The second search retrieved 1265 articles, with an average annual growth rate of 6.84%. Based on the publication trend line for this period, it is predicted that approximately 150 articles will be published in this field in 2024. <b>Conclusion:</b> In the future, the development of postmortem interval estimation will likely remain in a steady phase. Interdisciplinary interactions and constraints still exist. The future direction may focus on using multiomics approaches, combined with advancements in artificial intelligence, to establish comprehensive data models for more accurate postmortem interval estimation.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"86-97"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunita Das, Munesh Kumar, Vijay Sharma, Deep Roy, S K Tandon
{"title":"Sudden deaths linked to undiagnosed intracranial colloid cysts of third ventricle on autopsy: Series of five cases.","authors":"Sunita Das, Munesh Kumar, Vijay Sharma, Deep Roy, S K Tandon","doi":"10.1177/00258024251348729","DOIUrl":"10.1177/00258024251348729","url":null,"abstract":"<p><p>Sudden deaths may result from many conditions which are either not apparent at autopsy or might be missed and such cases can be tricky as there is no definite cause of death. One such entity is Intracranial colloid cysts, they are congenital neuroepithelial cysts which might be missed or might rupture at the time of dissection. They typically arise within the third ventricle of the brain and can pose a significant risk of sudden death if left undiagnosed or untreated. These are rare entity and on cut-section, these cysts contain mucoid and gelatinous material. In this paper, we have discussed in depth about five cases of colloid cysts, most of which were brought dead to the hospital and were discovered during autopsy without any prior history suggesting the same.</p>","PeriodicalId":18484,"journal":{"name":"Medicine, Science and the Law","volume":" ","pages":"80-85"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}