Menopause: The Journal of The North American Menopause Society最新文献

{"title":"Effects of pelvic floor muscle training combined with patient education in genitourinary syndrome of menopause: a randomized controlled trial.","authors":"Gizem Taşkıran, Arda Taşkın Taşkıran, Serap Özgül","doi":"10.1097/GME.0000000000002914","DOIUrl":"https://doi.org/10.1097/GME.0000000000002914","url":null,"abstract":"<p><strong>Objective: </strong>Evidence supporting the effects of pelvic floor muscle training (PFMT) in the management of genitourinary syndrome of menopause (GSM) is limited; nevertheless, patient education constitutes a fundamental therapeutic component that is frequently neglected. Therefore, the aim of this study was to investigate the effects of PFMT combined with patient education specific to GSM in postmenopausal women.</p><p><strong>Methods: </strong>Fifty-eight postmenopausal women diagnosed with GSM were randomized to the PFMT plus structured patient education group (study group, n=28) or the patient education-only group (control group, n=30). PFMT was implemented as a supervised and progressive program for 8 weeks. Primary outcome measures were vulvovaginal and urogenital symptom levels. Secondary outcome measures included the urinary incontinence (UI) impact, ability to stop urine flow, pelvic floor strength, and menopause-specific QoL. Statistical analyses were performed using analysis of covariance (ANCOVA) under both the intention-to-treat (ITT) and per-protocol (PP) approaches. The significance level was set at 5%.</p><p><strong>Results: </strong>The study group showed greater reductions in vulvovaginal and urogenital symptoms, UI impact (P<0.001), and sexual QoL scores (P<0.001). Pelvic floor muscle strength (P=0.001) and the proportion of participants able to stop urine flow (P=0.010) were also significantly higher in the study group. No significant between-group differences were observed in vasomotor, psychosocial, or physical QoL subdomains (P>0.05).</p><p><strong>Conclusions: </strong>Supervised PFMT combined with GSM-specific patient education appears to be an effective approach for GSM in postmenopausal women. Further studies with larger sample sizes investigating conservative interventions for GSM management are warranted, and long-term outcomes should be evaluated.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applying the Behavior Change Wheel to design physical activity interventions for women undergoing the menopause transition.","authors":"Amie Woodward, Frances Butler","doi":"10.1097/GME.0000000000002904","DOIUrl":"https://doi.org/10.1097/GME.0000000000002904","url":null,"abstract":"<p><strong>Objective: </strong>Physical activity (PA) is critical for mitigating cardiovascular disease risk during the menopause transition, yet participation often declines during this life stage. This study applied the Behavior Change Wheel (BCW), a comprehensive framework for designing evidence-based interventions, to identify determinants of PA and develop tailored strategies to support women in meeting UK PA guidelines.</p><p><strong>Methods: </strong>We conducted a behavioral diagnosis by integrating primary data from three focus groups with perimenopausal and postmenopausal women (n=14, 51.5±2.2 years) and findings from six qualitative studies. Data were coded using the Theoretical Domains Framework and the COM-B model (Capability, Opportunity, Motivation-Behavior). We then used the BCW to systematically select intervention functions, policy categories, and behavior change techniques (BCTs) to address identified determinants.</p><p><strong>Results: </strong>We identified 14 behavioral determinants across all COM-B domains. Interventions should address menopause-related physical capabilities and self-efficacy, caregiving identities that de-prioritize personal health, and anxiety regarding public exercise environments. Intervention functions including Training, Education, and Enablement can build confidence and skills, while modeling, and persuasion can be used to elevate positive role models and reframe PA as health-promoting behavior compatible with caregiving roles.</p><p><strong>Conclusions: </strong>This study outlines a theory-informed intervention package that provides recommendations to support PA engagement during midlife. Recommendations include providing menopause-specific technical support for safe PA, creating inclusive, nonjudgmental environments, and using BCTs like action planning and graded tasks to build sustainable habits. These findings offer an actionable foundation to develop future PA interventions that reflect the specific needs and lived experiences of women undergoing the menopause transition.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representaton of sexual dysfunction among top menopause content creators on TikTok: a cross-sectional content analysis.","authors":"Leona Hariharan, Sara J Ahsan, Tami S Rowen","doi":"10.1097/GME.0000000000002938","DOIUrl":"https://doi.org/10.1097/GME.0000000000002938","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate how menopause-related sexual dysfunction is represented in content from top menopause creators on TikTok, including symptom frequency, content framing, and creator characteristics.</p><p><strong>Methods: </strong>A cross-sectional content analysis was conducted in October 2025 using the keyword \"menopause.\" The 100 most-viewed TikTok videos posted between April and October 2025 were identified, and the 10 most influential content creators were selected based on follower count and engagement metrics. All videos posted by these creators during the study period were screened for eligibility, and 834 videos meeting the inclusion criteria were analyzed. Videos were coded for mentions of sexual function symptoms (vaginal dryness, libido changes, arousal difficulties, dyspareunia, and orgasmic challenges), broader menopause-related symptoms (mood changes, fatigue, hot flashes, bone or joint pain, and urinary incontinence), and content framing (symptom validation or empowerment, management strategies, product endorsements, or other).</p><p><strong>Results: </strong>Sexual symptoms were infrequently mentioned: vaginal dryness (3.5%), libido changes (7.9%), arousal difficulties (1.3%), dyspareunia (2.0%), and orgasmic challenges (0.1%). Broader menopause-related symptoms were discussed more frequently, including mood changes (31.2%), hot flashes (13.5%), and bone or joint pain (12.9%). Most videos focused on symptom validation or empowerment (51.6%), followed by management strategies (19.3%) and product endorsements (13.2%). Among the 10 most influential content creators, one was a medical professional.</p><p><strong>Conclusion: </strong>Menopause-related sexual dysfunction is underrepresented in content from top menopause creators despite its high prevalence. Its limited presence in widely viewed menopause content may reduce recognition of sexual dysfunction as a clinically relevant concern during menopause.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating menopausal neurocognitive and psychosocial dynamics into economic behavior: the Behavioral Finance-Menopausal Cognition (BF-MC) Model (MARiE WP2A study).","authors":"Gayathri Delanerolle, Maria Alva, Ieera Madan Aggarwal, Vindya Pathiraja, Jian Shi, Julie Taylor, Lucky Saraswat, Nick Panay, Vikram Talaulikar, George U Eleje, Nana Afful-Minta, Lamya Al-Kharusi, Nihal Al-Riyami, Bernard Mbwele, Pradip K Mitra, Muhammad Irfan, Rabia Kareem, Cristina Benetti-Pinto, Teck-Hock Toh, Helen F Kemp, Gowri Vaidyanathan, Ramya Palanisamy, Jeremy Van Vlymen, Peter Phiri, Sohier Elneil, Sam Halabi","doi":"10.1097/GME.0000000000002881","DOIUrl":"https://doi.org/10.1097/GME.0000000000002881","url":null,"abstract":"<p><strong>Objective: </strong>Traditional behavioral finance-which examines how cognitive biases, emotions, and context shape economic decision-making- often assumes cognitive stability, rationality, and consistent risk evaluation, based largely on male-dominated samples. Emerging evidence from the Menopause and Ageing Research in International Environments (MARIE) WP2a program, encompassing over 6,300 women across thirteen countries, suggests that the menopause transition brings about significant neurocognitive, emotional, and sociostructural changes that may influence financial decision-making processes. These influences remain under-theorized within current behavioral economics models. This study proposes a new conceptual framework-the Behavioral Finance-Menopausal Cognition (BF-MC) Model-that integrates menopause-related cognitive, psychological, and sociostructural dynamics with behavioral finance theory.</p><p><strong>Methods: </strong>A theory-building synthesis was conducted using quantitative and qualitative findings from the MARIE WP2a cohort. Menopausal symptom domains were mapped onto established behavioral finance constructs, such as risk aversion, present bias, and liquidity preference. The synthesis also explored sociostructural moderators across diverse contexts that shape these pathways. No empirical financial behavior data were analyzed in this framework.</p><p><strong>Results: </strong>The BF-MC Model identifies four interrelated domains: (1) neurocognitive regulation, (2) affective-behavioral regulation, (3) sociostructural mediation, and (4) economic adaptation and resilience. Menopausal symptom domains interact with sociocultural factors, such as employment conditions, caregiving responsibilities, and financial system design, to influence decision-making pathways. The model reframes midlife women's financial behavior as a dynamic biopsychosocial process rather than a deficit, highlighting adaptive responses to fluctuating cognitive and emotional resources.</p><p><strong>Conclusion: </strong>The BF-MC Model provides a conceptual framework to understand how menopausal cognitive and psychosocial changes may shape financial decision-making. It highlights potential pathways and moderators that warrant empirical testing, offering a foundation for future research on gender-responsive financial behavior and policy. While the model identifies plausible mechanisms, its pathways remain theoretical and require validation with longitudinal financial data.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussing menopausal symptoms at work and associations with taboo, symptom severity, and need for recovery after work.","authors":"Bette Loef, Karin I Proper, Michelle G A Clevis, Annemarie Y A M Reilingh, Irene G M van Valkengoed, Karen Nieuwenhuijsen, Sandra H van Oostrom","doi":"10.1097/GME.0000000000002910","DOIUrl":"https://doi.org/10.1097/GME.0000000000002910","url":null,"abstract":"<p><strong>Objective: </strong>Although the impact of menopausal symptoms at work is increasingly recognized, it remains unclear to what extent and with whom menopausal symptoms that limit work functioning are discussed. We examined this and explored associations with taboo, symptom severity, and need for recovery.</p><p><strong>Methods: </strong>Cross-sectional data of 9,977 perimenopausal and postmenopausal women from the Dutch Lifelines cohort were used. In 2024, participants reported on experiencing and discussing menopausal symptoms that limit work functioning, perceived taboo, and the need for recovery. Descriptive statistics were used to examine how often symptoms were discussed and with whom (colleagues, supervisors, [occupational] professionals), and regression analyses were used to explore associations with taboo, symptom severity, and need for recovery.</p><p><strong>Results: </strong>In total, 36.7% of women reported limitations in work functioning due to menopausal symptoms. Among them, 45.5% did not discuss their symptoms at work. Women with limitations who did not discuss their symptoms were more likely to perceive talking about menopause at work as taboo than women without limitations, particularly those who felt the need to talk about it but did not (odds ratio: 5.12, 95% confidence interval: 3.54-7.41). This last subgroup, together with women with limitations who discussed their symptoms with an (occupational) professional, experienced the highest symptom severity and need for recovery.</p><p><strong>Conclusions: </strong>Of perimenopausal and postmenopausal women who report work limitations due to menopausal symptoms, nearly half did not discuss these symptoms at work. The perceived taboo among women who did not discuss symptoms highlights the importance of an open workplace culture and accessible support to promote work participation during menopause.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating menopausal symptom burden and treatment engagement in a predominantly Hispanic population on the United States-Mexico border.","authors":"Amber McFerren, Kelcy Steffen-Gutierrez, Sarah Johnson, Alok Dwivedi, Katelyn Welshans, Sireesha Y Reddy","doi":"10.1097/GME.0000000000002898","DOIUrl":"https://doi.org/10.1097/GME.0000000000002898","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate menopausal symptom burden, health care engagement, and treatment disparities among postmenopausal women at the United States-Mexico border.</p><p><strong>Methods: </strong>A cross-sectional bilingual survey was administered to postmenopausal women receiving care from 2021 to 2024 at a tertiary care center. Menopausal symptoms, treatment use, and health care clinician engagement were assessed. Associations were evaluated using multivariable logistic or Poisson regression.</p><p><strong>Results: </strong>Among 340 postmenopausal participants (mean age: 55.8 ± 7.0 y), the most frequently reported symptoms were sleep disturbances (73%; 95% CI: 68%-77%) and weight gain (68%; 95% CI: 63%-73%). Despite this high symptom burden, 58% (95% CI: 52%-63%) reported that their symptoms had never been addressed by a clinician. Younger participants (<55 y) had higher odds of vasomotor, sleep, and mood symptoms (all P<0.01), while older participants were more likely to have discussed menopause with a clinician (adjusted odds ratio [aOR] 1.86; 95% CI: 1.16-2.97, P= 0.01) or used hormone therapy (aOR 2.91; 95% CI: 1.53-5.50, P= 0.001). Higher education was associated with hormone therapy use (aOR: 5.63; 95% CI: 1.09-29.08; P= 0.039) and mental health treatment (aOR: 4.11; 95% CI: 1.30-13.02; P= 0.016). Despite similar symptom prevalence, Hispanic participants were less likely to have received mental health treatment (aOR: 0.35; 95% CI: 0.19-0.65; P= 0.001).</p><p><strong>Conclusions: </strong>Menopausal symptoms were common in this border-region cohort, yet clinician engagement and treatment use were low. Socioeconomic and ethnic disparities in treatment highlight the need for culturally and linguistically tailored menopause care.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative medical group visits for menopause (MENOGAP): results of a pilot single-site feasibility study.","authors":"Lisa Taylor-Swanson, Wen Tu, Bob Wong, Xiaoming Sheng, Tammy Dunklebarger, Micaela Besser, Susan Smaellie, Hallie M Pedersen, Camille Moreno","doi":"10.1097/GME.0000000000002905","DOIUrl":"https://doi.org/10.1097/GME.0000000000002905","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;Up to 82% of midlife women experience vasomotor and other symptoms during the menopausal transition and post menopause. Midlife women express interest in both conventional and integrative health approaches to symptom management. MENOGAP is an intervention with evidence-informed conventional and integrative health education content and acupuncture therapy delivered in a group medical visit, thus enabling clinicians to provide much-needed care to more women simultaneously. Women also learn self-care for stress management and wellness promotion. Limited research has been conducted on integrative group medical visits for women in perimenopause or postmenopause. This single-arm study was conducted in one site to ascertain the feasibility of recruiting and retaining participants, and the acceptability of study procedures, including data collection, and to assess participants' outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;MENOGAP was co-delivered by a menopause-certified physician and an acupuncturist. The primary outcome was level of feasibility, acceptability, and appropriateness, as measured by the Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM), and Feasibility of Intervention Measure (FIM). Secondary outcomes include changes in menopause-related symptoms, assessed with the Menopause Rating Scale (MRS), menopause self-efficacy, self-care behaviors, and menopause knowledge. Descriptive statistics were used for demographics and feasibility scales. Paired t tests and McNemar tests were used to assess changes between measures at baseline and post-intervention. Qualitative data were coded using thematic content analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;No enrolled participants withdrew and 90.4% attended three or more sessions. Participants reported high rates of acceptability, appropriateness, and feasibility. Statistically significant differences between pre-scores and post-scores were observed in MRS (P=0.005), somato-vegetative subscale (P=0.026), and psychological subscale (P=0.050), with overall MRS scores decreasing by 0.294 points and the somato-vegetative subscale by 0.300 points, suggesting modest but potentially clinically relevant improvement; knowledge of the menopausal transition increased by 1.727 points (95% CI: 0.729-2.725, P=0.002), and menopause self-efficacy increased by 0.612 points (95% CI: 0.139-1.085, P=0.013). Themes from the qualitative data included positive experiences and enjoyment, empowerment and emotional support, time constraints and travel challenges, useful information delivery and materials, environment and comfort concerns, and follow-up and communication needs.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;MENOGAP was found to be feasible, acceptable, and effective from the perspectives of the enrolled participants. Physical and psychological symptoms improved significantly after the 4-week visits compared with baseline, and participants' knowledge of menopaus","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond strength and balance: advancing fall risk assessment after menopause.","authors":"Xuezhi Daniel Jiang","doi":"10.1097/GME.0000000000002921","DOIUrl":"https://doi.org/10.1097/GME.0000000000002921","url":null,"abstract":"","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the referral: building menopause competency in primary care.","authors":"Kimberly Ingelmo, Pallavi Khanna","doi":"10.1097/GME.0000000000002916","DOIUrl":"https://doi.org/10.1097/GME.0000000000002916","url":null,"abstract":"","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Withania somnifera root extract on sleep quality, body composition, and menopausal symptoms in postmenopausal women: a randomized, double-blind, placebo-controlled trial.","authors":"Simran Obhrai, Shweta Shenoy, Minaxi Arora","doi":"10.1097/GME.0000000000002894","DOIUrl":"https://doi.org/10.1097/GME.0000000000002894","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of Withania somnifera (ashwagandha) root extract supplementation on sleep quality, body composition, and menopausal symptoms in postmenopausal women.</p><p><strong>Methods: </strong>This randomized, double-blind, placebo-controlled trial enrolled 66 postmenopausal women aged 45-65 years at a single center in Amritsar, India. Participants were randomly assigned to receive either ashwagandha root extract (600 mg/day; n=34) or placebo (n=32) for 12 weeks. Primary outcomes were sleep quality assessed by the Pittsburgh Sleep Quality Index, body composition assessed by dual-energy x-ray absorptiometry, and menopausal symptoms assessed by the Menopause Rating Scale. Secondary outcomes included health-related quality of life assessed by the 36-Item Short Form Health Survey. Bone mineral density was assessed as an exploratory outcome.</p><p><strong>Results: </strong>Sixty-three participants completed the study (ashwagandha n=33; placebo n=30). The ashwagandha group demonstrated significantly greater improvements in sleep quality (mean change -5.2 vs. -0.8; P<0.001), menopausal symptom scores (mean change -8.1 vs. -1.2; P<0.001), and body fat percentage (mean change -0.6% vs. +0.03%; P<0.01) compared with placebo. Quality of life improved significantly across multiple domains. No significant between-group differences in bone mineral density were observed. The intervention was well tolerated with no serious adverse events.</p><p><strong>Conclusions: </strong>Twelve weeks of ashwagandha supplementation significantly improved sleep quality, menopausal symptoms, and body composition in postmenopausal women, with an excellent safety profile.</p>","PeriodicalId":18435,"journal":{"name":"Menopause: The Journal of The North American Menopause Society","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148969549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}