Medicine and Science in Sports and Exercise最新文献

{"title":"PROSPECTIVE ASSOCIATIONS OF PHYSICAL ACTIVITY AND SEDENTARY TIME IN ADOLESCENCE WITH CARDIOMETABOLIC RISK IN YOUNG ADULTHOOD.","authors":"Anders Husøy, Elin Kolle, Jostein Steene-Johannessen, Lars Bo Andersen, Sigmund Alfred Anderssen, Ulf Ekelund","doi":"10.1249/MSS.0000000000003595","DOIUrl":"https://doi.org/10.1249/MSS.0000000000003595","url":null,"abstract":"<p><strong>Abstract: </strong>Purpose: The relationship between sedentary time, physical activity, and cardiometabolic risk factors during the transition from adolescence to adulthood remain uncertain. We examined the prospective associations of sedentary time and physical activity at age 15 with cardiometabolic risk markers at age 24.Methods: We used data from the Physical Activity among Norwegian Children Studies (PANCS). Sedentary time, moderate-to-vigorous physical activity (MVPA), and vigorous physical activity (VPA) were measured by accelerometry. Outcomes included body mass index (BMI), waist circumference, visceral fat, maximal oxygen uptake (VO2max), systolic blood pressure, LDL-cholesterol, insulin, high-sensitivity CRP, and a clustered risk Z-score. The prospective associations were modelled through regression.Results: A total of 731 boys and girls participated at age 9 (2005-2006) and 15 (2011-2012), and 258 of these participated again at age 24 (2019-2021). Multiple imputation was performed for all eligible individuals (n = 708). Each standard deviation increase (min/day) in sedentary time at age 15 was associated with lower VO2max at age 24 (β: -1.6 ml/kg/min; 95%CI: -2.8, -0.5). Each standard deviation increase (min/d) in MVPA (β: 1.6 ml/kg/min; 95%CI: 0.8, 2.4) and VPA (β: 1.6 ml/kg/min; 95%CI: 0.8, 2.4) at age 15 were associated with higher VO2max at age 24. VPA in adolescence was further inversely associated with visceral fat mass (β: -41 g; 95%CI: -78, -3), insulin level (β: -4.3 pmol/L; 95%CI: -8.2, -0.4), and the clustered risk Z-score (β: -0.09; 95%CI: -0.18, -0.01) in young adulthood. Childhood BMI modified the association of both MVPA and VPA with clustered risk, with the greatest magnitude of association observed in the highest BMI tertile.Conclusions: Physical activity, especially of vigorous intensity, during adolescence appear to beneficially affect cardiometabolic health in young adulthood. These health benefits may be most pronounced among overweight/obese youth.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Low-Impact Resistance Exercise Program Increases Strength and Balance in Females Irrespective of Menopause Status.","authors":"Erika Svensen, Christopher P Koscien, Nima Alamdari, Benjamin T Wall, Francis B Stephens","doi":"10.1249/MSS.0000000000003586","DOIUrl":"10.1249/MSS.0000000000003586","url":null,"abstract":"<p><strong>Introduction: </strong>The reduction in sex hormone production across the menopause transition is thought to accelerate age-related decline in muscle mass, strength, and stability, increasing the risk of falls and fractures. We aimed to investigate whether a novel low-impact resistance exercise program could improve strength, balance, and body composition and whether any improvement was affected by menopause status.</p><p><strong>Methods: </strong>Seventy healthy, moderately active pre- (PRE; 46.7 ± (SD) 3.2 years), peri- (PERI; 52.3 ± 2.2 years) or post- (POST; 57.0 ± 2.5 years) menopausal females, not taking hormone replacement therapy (HRT), were randomised to continue habitual physical activity (CON; n = 25) or complete a supervised resistance exercise program 4 days/week for 12 weeks (EXC; n = 45). Strength at the hip and shoulder (isokinetic dynamometer), dynamic balance (Y-balance), flexibility (sit-and-reach & back-scratch), muscle thickness (rectus femoris, vastus intermedius (VI) and medial deltoid), and lean and %body fat (dual-energy X-ray absorptiometry) were measured before and after training. Results: Hip abduction and flexion peak torque (19 ± 48 and 20 ± 17%, respectively, P < 0.05), posterolateral and posteromedial balance (12 ± 15 and 13 ± 15%, respectively, P < 0.001), flexibility (21 ± 36%, P < 0.001), VI thickness (12 ± 19%, P = 0.032), lean mass (2 ± 2%, P = 0.007), all increased over 12 weeks in EXC, but not CON, with no difference in response between PRE, PERI or POST. The changes in shoulder strength and body mass over 12 weeks were not different between CON and EXC.</p><p><strong>Conclusions: </strong>This is the first study to demonstrate that the decline in sex hormones, and increase in age, across the menopause transition does not affect the ability of lower limb (hip) strength and balance to adapt to a low-impact resistance exercise training program in females not taking HRT.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bolstering the Prognostic Utility of Coronary Risk Assessments with PAI: A Physical Activity Metric.","authors":"Javaid Nauman, Tania Mirzaamin, Barry A Franklin, Bjarne M Nes, Carl J Lavie, Patrick Dunn, Ross Arena, Chi Pang Wen, Atefe R Tari, Ulrik Wisløff","doi":"10.1249/MSS.0000000000003584","DOIUrl":"https://doi.org/10.1249/MSS.0000000000003584","url":null,"abstract":"<p><strong>Purpose: </strong>Personal Activity Intelligence (PAI) translates heart rate during physical activity (PA) into a weekly score, that credits vigorous over low- and moderate intensity PA. We prospectively investigated the association between PAI and fatal and non-fatal coronary heart disease (CHD) in self-reported healthy participants from Norway, with specific reference to improving the accuracy of conventional coronary risk assessment.</p><p><strong>Methods: </strong>We studied 40 961 healthy adults (56% women) from the population based Trøndelag Health Study (the HUNT study). Individual data were linked to hospital and cause of death registries. The weekly PAI score of each participant was divided into four groups (PAI scores of 0, ≤50, 51-99, or ≥ 100). Adjusted hazard ratios [aHRs] and 95% confidence intervals (CIs) for fatal and non-fatal CHD related to PAI were estimated using Cox proportional hazard regression analyses.</p><p><strong>Results: </strong>During a median follow-up period of 13.1 years (IQR, 12.7-13.6), 3303 (3109 non-fatal, 194 fatal) CHD events occurred. Compared with the inactive group (0 PAI), weekly PAI scores at baseline of 51-99 and ≥ 100 were associated with a lower risk of CHD [0.80 (0.71-0.91) and 0.86 (0.78-0.95), respectively]. By adding PAI to traditional risk factors, the net reclassification improvement of CHD was 0.472 (P < 0.001).</p><p><strong>Conclusions: </strong>PAI was inversely associated with CHD risk among healthy participants at baseline, and it's cardioprotective effect persisted across diverse risk factor profiles. A PAI score > 50 was substantially associated with a reduced risk of CHD. These findings have implications for improving the accuracy of conventional coronary risk assessments with PAI.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Durability of Running Economy: Differences between Quantification Methods and Performance Status in Male Runners.","authors":"Michele Zanini, Jonathan P Folland, Richard C Blagrove","doi":"10.1249/MSS.0000000000003499","DOIUrl":"10.1249/MSS.0000000000003499","url":null,"abstract":"<p><strong>Introduction: </strong>Running economy (RE) deteriorates during prolonged running, although the effect of measuring energy cost (EC) or oxygen cost (OC) on the magnitude of these changes has not been investigated. Similarly, it is unknown if runners' performance level may influence the deterioration of RE during prolonged running. The aims of this study were to compare changes in EC and OC measurements of RE during a prolonged run in a large cohort of well-trained male runners, and to compare changes between runners of high- and low-performance standard.</p><p><strong>Methods: </strong>Forty-four male runners (maximal oxygen uptake (V̇O 2max ) 62.4 mL·kg -1 ·min -1 ; 10-km time: 35:50 ± 4:40 mm:ss) completed an incremental test determining lactate threshold 1 (LT1) and V̇O 2max , and on a separate occasion, a 90-min run at LT1. Respiratory gases were collected at 15-min intervals. Subsequently, subgroups of high- (HP; 10-km time: 31:20 ± 01:00 mm:ss) and low-performing (LP; 10-km time: 41:50 ± 01:20 mm:ss) runners were compared.</p><p><strong>Results: </strong>RE deterioration was only fractionally larger when expressed as OC than EC (0.1% greater from 30-90 min; P < 0.001), perhaps due to the small change in respiratory exchange ratio (-0.01) in this study. For the HP group, increases were lower than LP after 90 min in both EC (+2.3% vs +4.3%; P < 0.01) and OC (+2.4% vs +4.5%; P < 0.01). Similarly, at standardized distances, changes were lower for HP versus LP, for example, at 16.7 km + 1.0 versus +3.2% for EC ( P < 0.01), and +1.2 vs +3.4% for OC ( P < 0.001).</p><p><strong>Conclusions: </strong>The deterioration of RE was dependent on athlete's performance level, with HP runners displaying superior RE durability. The use of EC or OC had only a fractional influence on RE durability, although this may gain importance with larger shifts in substrate metabolism.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2230-2240"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allostatic Load Is Associated with Overuse Musculoskeletal Injury during US Marine Corps Officer Candidates School.","authors":"Evan D Feigel, Matthew B Bird, Kristen J Koltun, Mita Lovalekar, Jennifer N Forse, Catherine R Gage, Elizabeth J Steele, Christopher K Kargl, Brian J Martin, Angelique Bannister, Angelito V Cruz, Tim L A Doyle, Karl E Friedl, Bradley C Nindl","doi":"10.1249/MSS.0000000000003507","DOIUrl":"10.1249/MSS.0000000000003507","url":null,"abstract":"<p><strong>Introduction: </strong>Overuse musculoskeletal injuries (MSKI) remain a significant medical challenge in military personnel undergoing military training courses; further understanding of the biological process leading to overuse MSKI development and biological signatures for injury risk are warranted. The purpose of this study was to determine the association between overuse MSKI occurrence and physiological characteristics of allostatic load characterized as maladaptive biological responses to chronic stress measured by wearable devices in US Marine Corps officer candidates during a 10-wk training course.</p><p><strong>Methods: </strong>Devices recorded energy expenditure (EE), daytime heart rate (HR), sleeping HR, and sleep architecture (time and percentage of deep, light, rapid eye movement sleep, awake time, total sleep). Flux was calculated as the raw or absolute difference in the average value for that day or night and the day or night beforehand. Linear mixed-effect model analysis accounting for cardiorespiratory fitness assessed the association between overuse MSKI occurrence and device metrics ( α = 0.05).</p><p><strong>Results: </strong>Sixty-nine participants (23 females) were included. Twenty-one participants (eight females) sustained overuse MSKI. Overuse MSKI occurrence in male participants was positively associated with daytime HR ( β = 5.316, P = 0.008), sleeping HR ( β = 2.708, P = 0.032), relative EE ( β = 8.968, P = 0.001), absolute flux in relative EE ( β = 2.994, P = 0.002), absolute EE ( β = 626.830, P = 0.001), and absolute flux in absolute EE ( β = 204.062, P = 0.004). Overuse MSKI occurrence in female participants was positively associated with relative EE ( β = 5.955, P = 0.026), deep sleep time ( β = 0.664, P < 0.001), and percent deep sleep ( β = 12.564, P < 0.001) and negatively associated with absolute flux in sleeping HR ( β = -0.660, P = 0.009).</p><p><strong>Conclusions: </strong>Overuse MSKI occurrences were associated with physiological characteristics of allostatic load, including chronically elevated HR and EE and greater time in restorative sleep stages, which may serve as biological signatures for overuse MSKI risk.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2220-2229"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141457965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Physiological and Performance Development of Two Multiple Olympic Champion Rowers: A 20-Year Follow-Up Study.","authors":"Pavle Mikulic, Jere Gulin","doi":"10.1249/MSS.0000000000003504","DOIUrl":"10.1249/MSS.0000000000003504","url":null,"abstract":"<p><strong>Purpose: </strong>This study reports the results of a 20-yr (2005 to 2024) follow-up study of two 2-time Olympic and 6-time world champion rowing athletes. To provide a comprehensive picture of adaptations in physiological and performance characteristics to long-term training, we monitored the athletes' physiological and performance data annually through five 4-yr developmental phases.</p><p><strong>Methods: </strong>Maximal oxygen uptake (V̇O 2max ), maximal minute power (MMP), and power output corresponding to anaerobic threshold (PAT) were derived from a rampwise exercise test on a rowing ergometer. In addition, average power output sustained during all-out tests over 2000 and 6000 m on a rowing ergometer was also obtained.</p><p><strong>Results: </strong>V̇O 2max peaked at age 22 for athlete A and at age 25 for athlete B (at ~7 L·min -1 ) before stabilizing and then gradually declining to a range of 6.2 to 6.5 L·min -1 for both athletes. MMP stabilized in both rowers at values between 550 and 575 W and displayed minimal fluctuations over the final two phases of the study. In addition, MMP closely resembled the corresponding average power output sustained during the 2000-m all-out tests on a rowing ergometer. Average power output during 2000 and 6000-m all-out tests showed steady improvements over the monitored phases of the study, with the highest power output crew averages for both 2000-m (532 W; 5 min 48 s) and 6000-m (463 W; 18 min 4 s) tests recorded during the last 4-yr phase of the assessment.</p><p><strong>Conclusions: </strong>Improvements in rowing ergometer performance over 2000 and 6000 m appear to be largely independent of the multiyear changes in V̇O 2max . Long-term rowing training resulted in continuous improvements in MMP and PAT throughout the monitored phases, which more closely mimicked improvements in rowing ergometer performance.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2211-2219"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Multi-Ingredient Protein versus Collagen Supplementation on Satellite Cell Properties in Males and Females.","authors":"Mai Wageh, Stephen A Fortino, Riley Pontello, Ahmed Maklad, Chris McGlory, Dinesh Kumbhare, Stuart M Phillips, Gianni Parise","doi":"10.1249/MSS.0000000000003505","DOIUrl":"10.1249/MSS.0000000000003505","url":null,"abstract":"<p><strong>Introduction: </strong>Skeletal muscle satellite cells (SC) contribute to the adaptive process of resistance exercise training (RET) and may be influenced by nutritional supplementation. However, little research exists on the impact of multi-ingredient supplementation on the SC response to RET.</p><p><strong>Purpose: </strong>We tested the effect of a multi-ingredient supplement (MIS) including whey protein, creatine, leucine, calcium citrate, and vitamin D on SC content and activity as well as myonuclear accretion, SC and myonuclear domain compared with a collagen control (COL) throughout a 10-wk RET program.</p><p><strong>Methods: </strong>Twenty-six participants underwent a 10-wk linear RET program while consuming either the MIS or COL supplement twice daily. Muscle biopsies were taken from the vastus lateralis at baseline and 48 h after a bout of damaging exercise, before and after RET. Muscle tissue was analyzed for SC and myonuclear content, domain, acute SC activation, and fiber cross-sectional area (fCSA).</p><p><strong>Results: </strong>MIS resulted in a greater increase in type II fCSA following 10 wk of RET (effect size (ES) = 0.89) but not myonuclear accretion or SC content. Change in myonuclei per fiber was positively correlated with type I and II and total fiber hypertrophy in the COL group only, indicating a robust independent effect of MIS on fCSA. Myonuclear domain increased similarly in both groups, whereas SC domain remained unchanged following RET. SC activation was similar between groups for all fiber types in the untrained state but showed a trend toward greater increases with MIS after RET (ES = 0.70).</p><p><strong>Conclusions: </strong>SC responses to acute damaging exercise and long-term RET are predominantly similar in MIS and COL groups. However, MIS can induce greater increases in type II fCSA with RET and potentially SC activation following damage in the trained state.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":"56 11","pages":"2125-2134"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142546336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Aging on the Unfolded Protein Response in Human Skeletal Muscle at Rest and after Acute Exercise.","authors":"Kelly L Michie, Hawley E Kunz, Surendra Dasari, Ian R Lanza","doi":"10.1249/MSS.0000000000003508","DOIUrl":"10.1249/MSS.0000000000003508","url":null,"abstract":"<p><strong>Background: </strong>The unfolded protein response (UPR) is a proteostatic process that is activated in response to endoplasmic reticulum stress. It is currently unclear how aging influences the chronic and adaptive UPR in human skeletal muscle. Here we determined the effect of aging on UPR activation at rest, in response to exercise, and the associations with muscle function.</p><p><strong>Methods: </strong>Thirty young (20-35 yr) and 50 older (65-85 yr) individuals were enrolled. Vastus lateralis biopsies were performed at rest and 3 and 48 h after a single bout of resistance exercise. The abundance of UPR-related transcripts and proteins was measured by RNA sequencing and Western blotting, respectively. Fractional synthetic rates of muscle protein were determined by mass spectrometry after intravenous infusion of 13 C 6 phenylalanine.</p><p><strong>Results: </strong>Older adults demonstrated elevated transcriptional and proteomic markers of UPR activation in resting muscle. Resting UPR gene expression was negatively associated with muscle strength and power in older adults. The UPR is similarly activated by acute resistance exercise in young and older adults and positively associated with muscle function but not the anabolic response to exercise.</p><p><strong>Conclusions: </strong>Skeletal muscle from older adults exhibits chronically activated UPR, which accompanies functional decline. The adaptive UPR is a proteostatic mechanism that is upregulated in response to exercise in young and older adults and positively associated with muscle function.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2135-2145"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141457969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Eccentric versus Concentric Cycling Exercise on Neuromuscular Fatigue and Muscle Damage in Breast Cancer Patients.","authors":"Elyse Hucteau, Joris Mallard, Chiara Barbi, Massimo Venturelli, Roland Schott, Philippe Trensz, Carole Pflumio, Michal Kalish-Weindling, Xavier Pivot, Fabrice Favret, Guillaume P Ducrocq, Stéphane P Dufour, Allan F Pagano, Thomas J Hureau","doi":"10.1249/MSS.0000000000003506","DOIUrl":"10.1249/MSS.0000000000003506","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigated the magnitude and etiology of neuromuscular fatigue and muscle damage induced by eccentric cycling compared with conventional concentric cycling in patients with breast cancer.</p><p><strong>Methods: </strong>After a gradual familiarization protocol for eccentric cycling, nine patients with early-stage breast cancer performed three cycling sessions in eccentric or concentric mode. The eccentric cycling session (ECC) was compared with concentric cycling sessions matched for power output (CON power ; 80% of concentric peak power output, 95 ± 23 W) or oxygen uptake ( ; 10 ± 2 mL·min·kg -1 ). Preexercise to postexercise changes (30-s through 10-min recovery) in knee extensor maximal voluntary contraction force (MVC), voluntary activation, and quadriceps potentiated twitch force ( Qtw ) were quantified to determine global, central, and peripheral fatigue, respectively. Creatine kinase and lactate dehydrogenase activities were measured in the plasma before and 24 h after exercise as markers of muscle damage.</p><p><strong>Results: </strong>Compared with CON power (-11% ± 9%) and (-5% ± 5%), the ECC session resulted in a greater decrease in MVC (-25% ± 12%) postexercise ( P < 0.001). Voluntary activation decreased only in ECC (-9% ± 6% postexercise, P < 0.001). The decrease in Qtw was similar postexercise between ECC and CON power (-39% ± 21% and -40% ± 16%, P > 0.99) but lower in ( P < 0.001). The CON power session resulted in twofold greater compared with the ECC and sessions ( P < 0.001). No change in creatine kinase or lactate dehydrogenase activity was reported from preexercise to 24 h postexercise.</p><p><strong>Conclusions: </strong>The ECC session induced greater neuromuscular fatigue compared with the concentric cycling sessions without generating severe muscle damage. ECC is a promising exercise modality for counteracting neuromuscular maladaptation in patients with breast cancer.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2103-2116"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aquatic High-Intensity Interval Deep Water Running Influence on Cardiometabolic Health and Cognitive Psychological Responses in Women.","authors":"Manny M Y Kwok, Shamay S M Ng, Jonathan Myers, Billy C L So","doi":"10.1249/MSS.0000000000003500","DOIUrl":"10.1249/MSS.0000000000003500","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effects of an 8-wk AHIIT-DWR intervention compared with land-based HIT training (LHIIT) on cardiometabolic health, cognitive, and psychological outcomes in inactive elderly women.</p><p><strong>Methods: </strong>Seventy inactive elderly women aged 60 yr or above were randomly assigned into two groups: AHIIT-DWR and LHIIT. The AHIIT-DWR group engaged in DWR sessions comprising 30 min of interval training, consisting of ten 2-min exercise bouts at 80%-90% of their maximal heart rate (HR max ), with 1-min active recovery at 70% HR max between bouts, for two sessions per week, for 8 wk. The LHIIT group performed treadmill running at the same intensity.</p><p><strong>Results: </strong>Both groups showed similar cardiovascular fitness, maximal aerobic capacity (V̇O 2max ), HR max , and RER improvement ( P > 0.05), whereas AHIIT-DWR showed a significant improvement in aerobic capacity minute ventilation (V̇E), metabolic equivalents (METs), and O 2 pulse ( P < 0.05) over the 8-wk intervention. Both AHIIT-DWR and LHIIT significantly decreased triglycerides, total cholesterol, HDL, and LDL postintervention ( P < 0.05). No significant group differences were observed for cognitive function assessed by MMSE and MOCA ( P > 0.05). Both groups showed similar enjoyment levels, self-efficacy scores, and high adherence rates (>90%).</p><p><strong>Conclusions: </strong>Our study suggests that AHIIT-DWR can elicit a similar improvement in cardiorespiratory health, metabolic blood markers, cognitive function assessed by MMSE and MOCA, and psychological responses as LHIIT in inactive elderly women.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"2203-2210"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141419801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}