Impact of Vegan Diets on Resistance Exercise-Mediated Myofibrillar Protein Synthesis in Healthy Young Males and Females: A Randomized Controlled Trial.

IF 3.9 2区 医学 Q1 SPORT SCIENCES
Andrew T Askow, Takeshi M Barnes, Zan Zupancic, Max T Deutz, Kevin J M Paulussen, Colleen F McKenna, Amadeo F Salvador, Alexander V Ulanov, Scott A Paluska, Jared W Willard, Steven J Petruzzello, Nicholas A Burd
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引用次数: 0

Abstract

Background: Protein ingestion stimulates muscle protein synthesis (MPS) rates to support the turnover of skeletal muscle protein mass. However, dietary patterns consist of a variety of protein foods with different amino acid compositions consumed at multiple meal times throughout the day. Omnivorous (OMN) and vegan (VGN) dietary patterns may differentially stimulate MPS. Moreover, the distribution and frequency of protein intake may also play an important anabolic regulatory role.

Objective: We aimed to determine the effect of OMN and VGN dietary patterns and protein distribution (balanced (B) and unbalanced (UB)) in regulating changes in daily myofibrillar protein synthesis rates during a 9-d resistance training intervention.

Design: Forty healthy, physically active males and females (28 males, 12 females; 25 ± 4 yr; body mass index, 24.1 ± 2.1 kg·m -2 ) consumed a weight-maintenance diet providing 1.1-1.2 g·kg -1 ·d -1 of dietary protein from an OMN or VGN dietary pattern with UB (10%, 30%, and 60% of daily protein at meals 1, 2, and 3, respectively) or B (20% of daily protein at five eating occasions) distribution. Participants completed whole-body resistance exercise three times during the controlled feeding trial while consuming deuterated water (D 2 O) for the measurement of daily myofibrillar protein synthesis rates.

Results: The percent kilocalories from carbohydrate was higher ( P = 0.045) in the OMN compared with VGN groups, but no other differences in dietary intakes were observed. Myofibrillar protein synthesis rates did not differ between the OMN-UB (3.04% ± 1.85%·d -1 ), OMN-B (2.43% ± 1.21%·d -1 ), VGN-UB (2.52% ± 1.77%·d -1 ), and VGN-B (2.49% ± 1.56%·d -1 ) groups (all P > 0.05).

Conclusions: Our results demonstrated that the anabolic action of animal versus vegan dietary patterns is similar. Moreover, there is no regulatory influence of distribution between the two dietary patterns on the stimulation of myofibrillar protein synthesis rates in young adults.This trial was registered with ClinicalTrials.gov (NCT04232254).

纯素饮食对健康年轻男性和女性抵抗运动介导的肌原纤维蛋白合成的影响:一项随机对照试验。
背景:蛋白质摄入刺激肌肉蛋白质合成率(MPS),以支持骨骼肌蛋白质质量的周转。然而,饮食模式是由各种蛋白质食物组成的,这些食物含有不同的氨基酸组成,在一天中的不同用餐时间被食用。杂食(OMN)和素食(VGN)的饮食模式可能会不同地刺激MPS。此外,蛋白质摄入的分布和频率也可能起着重要的合成代谢调节作用。目的:我们旨在确定OMN和VGN饮食模式和蛋白质分布(平衡[B]和不平衡[UB])在9天阻力训练干预期间调节每日肌原纤维蛋白合成率变化的作用。设计:40名身体健康,身体活跃的男性和女性(28 M, 12 F;25±4 y;体重指数= 24.1±2.1 kg·m-2),采用OMN或VGN饮食模式,提供1.1-1.2 g·kg-1·d-1的膳食蛋白质,其中UB(第1、2和3餐分别占每日蛋白质的10%、30%和60%)或B(5次进食时每日蛋白质的20%)分布。在控制喂养试验期间,参与者完成了三次全身阻力运动,同时消耗了氘水(D2O)来测量每日肌原纤维蛋白合成率。结果:与VGN组相比,OMN组来自碳水化合物的%kcal更高(P = 0.045),但在饮食摄入量方面没有观察到其他差异。OMN-UB组(3.04±1.85%·d-1)、OMN-B组(2.43±1.21%·d-1)、VGN-UB组(2.52±1.77%·d-1)、VGN-B组(2.49±1.56%·d-1)肌原纤维蛋白合成率差异无统计学意义(P < 0.05)。结论:我们的研究结果表明动物与纯素饮食模式的合成代谢作用是相似的。此外,两种饮食模式之间的分布对青壮年肌原纤维蛋白合成率的刺激没有调节影响。该试验已在ClinicalTrials.gov注册(NCT04232254)。
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来源期刊
CiteScore
7.70
自引率
4.90%
发文量
2568
审稿时长
1 months
期刊介绍: Medicine & Science in Sports & Exercise® features original investigations, clinical studies, and comprehensive reviews on current topics in sports medicine and exercise science. With this leading multidisciplinary journal, exercise physiologists, physiatrists, physical therapists, team physicians, and athletic trainers get a vital exchange of information from basic and applied science, medicine, education, and allied health fields.
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