Medicina-buenos Aires最新文献_第8页

[An electronic synapse]. [电子突触]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Basilio A Kotsias

引用次数: 0

[Bronchial infestation due to myiasis]. [因蝇蛆病引起的支气管感染]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Agustina Carrabs, Marisol Zinni, Emanuel J Saad, Manuel España, Mario E F Bustos

引用次数: 0

Perspectives on the efficacy and effectiveness of the recombinant herpes zoster vaccine. 重组带状疱疹疫苗的疗效和有效性研究进展。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Sebastián Garcia-Zamora, Laura Pulido, Álvaro Sosa-Liprandi

引用次数: 0

[Phlegmonous gastritis in a patient with chemotherapy induced neutropenia]. 化疗引起中性粒细胞减少的痰性胃炎1例。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Eugenio Cautures, Octavio E Chiocca, María Antonela Orellano, Juan Ignacio Ibarzabal, Juan Carlos Pendino, Lisandro R Bettini

引用次数: 0

[Encapsulated pseudoaneurysm post-left ventricular rupture: unusual presentation and follow-up]. 左心室破裂后包裹性假性动脉瘤：不寻常的表现和随访。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Mariano G Bergier, Santiago Del Castillo, Rodrigo Bagnati, Juan Benger, Sebastián Tonso, Diego Pérez De Arenaza, Mariano Falconi, Rodolfo Pizarro

{"title":"[Encapsulated pseudoaneurysm post-left ventricular rupture: unusual presentation and follow-up].","authors":"Mariano G Bergier, Santiago Del Castillo, Rodrigo Bagnati, Juan Benger, Sebastián Tonso, Diego Pérez De Arenaza, Mariano Falconi, Rodolfo Pizarro","doi":"","DOIUrl":"","url":null,"abstract":"External cardiac rupture with the development of a pseudoaneurysm is an uncommon complication of acute myocardial infarction (AMI) and do not always have typical presentations and can be challenging to diagnose. We present the case of a 59-year-old woman with no relevant cardiovascular history whose disease course was unusual. She initially presented with chest pain, dyspnea, and fever, and was diagnosed and treated for community-acquired pneumonia. Due to persistent symptoms, she went to the hospital where an electrocardiogram showed signs of an infarction. An echocardiogram revealed apical akinesia with a severely depressed ejection fraction and an associated thrombus. An AMI with differential diagnoses of an apical aneurysm versus a pseudoaneurysm was considered, and she was transferred to our center for further evaluation. The coronary angiography revealed an occlusion in the mid-left anterior descending artery, with no other significant lesions. The magnetic resonance imaging and the computed tomography scans showed severe left ventricular dysfunction, subacute infarction, and an apical pseudoaneurysm with a fragmented thrombus. A surgical resolution was considered, but the computed tomography scans revealed severe emphysema, and the pulmonary function tests showed severe obstructive ventilatory impairment. Any type of intervention was considered high risk, and it was decided to continue with medical treatment. Nine months later, the patient is still alive and asymptomatic.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 1","pages":"225-228"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Definition of high-priced and very high-priced drugs for Argentina]. [阿根廷高价和非常高价药品的定义]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Manuel Donato, Fernando Tortosa, Guadalupe Montero, Daniel E Manoukian, Agustín Iglesias, María Julia Meschini, Gustavo H Marin

{"title":"[Definition of high-priced and very high-priced drugs for Argentina].","authors":"Manuel Donato, Fernando Tortosa, Guadalupe Montero, Daniel E Manoukian, Agustín Iglesias, María Julia Meschini, Gustavo H Marin","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: New drugs contribute to improving people's quality of life with more precise and effective treatments; however, their high acquisition prices continually put the sustainability of the health system and equitable access at risk throughout the world. A starting point for its approach should be to delimit the concept of \"high-price\" and \"very high-price\" drugs, but there is no global consensus and it is not defined for Argentina. The objective was to establish the definition of high-price and very high-price drugs for Argentina through a panel with modified Delphi technique with representatives of the health system.Materials and methods: A descriptive study was conducted with a qualitative-quantitative approach in three phases that include a Phase 1 systematic review of the literature, a Phase 2 analysis of the profile of selected drugs, and a Phase 3 panel.Results: For the systematic review, 1895 publications were identified, of which 23 were included with some type of definition of high-cost or high-price drugs. A clinical and economic analysis was performed for ten reference drugs that provided examples to the panel. The modified Delphi panel consisted of a first round of 14 and a second round of consensus of 27 representatives, which resulted in the agreed definition.Discussion: This work collect the experience and vision of representatives of important institutions in our country and provides a key definition for addressing these technologies.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 2","pages":"261-280"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracic outlet syndrome secondary to a cavernous hemangioma of the first rib. 继发于第一肋骨海绵状血管瘤的胸廓出口综合征。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Agustín Buero, Soledad Olivera Lopez, Constanza Pereyra, Michel David, Leonardo G Pankl, Mayra Samudio, Julián Méndez, Gustavo A Lyons, Domingo J Chimondeguy

引用次数: 0

[Surgical outcomes post neoadjuvant immunotherapy in lung cancer: CheckMate 816 in Argentine subpopulation]. [肺癌新辅助免疫治疗后的手术结果：阿根廷亚群的CheckMate 816]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Alejandro Damonte, Joaquín García Morato, Soledad Courreges, Agustín Omati Porte, Aldo Perfetti, Patricio Levit, José A Rodriguez Zamboni

{"title":"[Surgical outcomes post neoadjuvant immunotherapy in lung cancer: CheckMate 816 in Argentine subpopulation].","authors":"Alejandro Damonte, Joaquín García Morato, Soledad Courreges, Agustín Omati Porte, Aldo Perfetti, Patricio Levit, José A Rodriguez Zamboni","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The CheckMate 816 study, a global phase III randomized trial, demonstrated that neoadjuvant treatment with nivolumab plus chemotherapy significantly improves event-free survival in patients with resectable non-small cell lung cancer (NSCLC). Additionally, the treatment significantly increases the rate of complete pathological response. We present the results of CheckMate 816 in an Argentine subpopulation to evaluate the efficacy and safety of the neoadjuvant treatment.Materials and methods: A retrospective observational and descriptive study was conducted at a high-volume single center in Argentina from January 2023 to March 2024. Patients received 360 mg of nivolumab plus chemotherapy and a platinum doublet every three weeks for three cycles before undergoing definitive surgery. The results were compared with the international trial and the Japanese population subgroup.Results: Nine patients received neoadjuvant therapy, of whom eight underwent definitive surgery. All patients achieved complete (R0) resection, and in three cases, a complete pathological response was observed. Currently, all are alive and disease-free.Discussion: The results obtained in the Argentine subpopulation were consistent with those observed in the global population and the Japanese subgroup. A high proportion of patients achieved a complete pathological response, an early indicator of therapeutic efficacy. Neoadjuvant therapy with nivolumab plus chemotherapy could be considered an effective treatment option for Argentine patients with resectable NSCLC.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 1","pages":"47-55"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Uncommon or unusual encephalopathies]. [不常见或不寻常的脑病]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Sebastián Villate, Natalia Lucero, Natalia Conci, Cecilia Cabanellas, Carla Buonanotte, Federico Buonanotte

引用次数: 0

[The role of pre-test probability in calculating predictive values in diagnostic studies]. [预测概率在诊断研究中计算预测值中的作用]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Gabriela V Carro, Alberto Velazquez

引用次数: 0