Medicina-buenos Aires最新文献_第10页

[Benign infant myositis associated to influenza B]. [与乙型流感有关的婴儿良性肌炎]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Jimena Bergilli, Antonella Magnano, Romanette Hurtado Latapiat, Sandra Barreiro, Martín Brizuela

引用次数: 0

[Borges, physics and art]. [博尔赫斯、物理学和艺术］

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Pablo Young, Alberto Rojo

引用次数: 0

[Disorders in plasmatic levels of potassium, magnesium, and calcium in elderly adults associated with colistin: time series]. [老年人血浆中钾、镁和钙水平的紊乱与可乐定有关：时间序列]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Angélica Tang, Matías Zamudio, Ernesto Federico Sena, María Pía Izaguirre Germain, Diego Caruso

{"title":"[Disorders in plasmatic levels of potassium, magnesium, and calcium in elderly adults associated with colistin: time series].","authors":"Angélica Tang, Matías Zamudio, Ernesto Federico Sena, María Pía Izaguirre Germain, Diego Caruso","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Water and electrolyte disturbances associated with colistin are understudied adverse effects in the medical literature. We aim to evaluate their incidence in hospitalized older adult patients.Materials and methods: A longitudinal retrospective study of the interrupted time series type was conducted on patients admitted to Dr. César Milstein Hospital. We included adults aged 65 and older who received colistin with normal serum potassium, magnesium, and calcium at the outset. Electrolyte values were collected before, during and after suspending the antibiotic. Values were compared using non-parametric tests, and a multivariate linear regression model with robust intervals was performed to assess sociodemographic and clinical characteristics associated with serum concentrations.Results: A total of 89 patients were included. The rate of hypokalemia was 77.5% (n=69), and factors associated with potassium decline included older age, increased creatinine levels, and longer colistin treatment duration. Serum magnesium disturbances were reported in 66 (79.5%) of the 83 patients evaluated. The decrease in both electrolytes was statistically significant in the measured times and both values normalized after 72 hours of stopping antibiotic therapy. The incidence of acute kidney injury during colistin treatment in patients with normal baseline creatinine was 63.6% (n = 42/66), and in those with abnormal baseline creatinine, it was 47.8% (n = 11/23).Conclusion: We report high rates of electrolyte disturbances in patients treated with colistin, with hypokalemia being the most frequent, showing resolution following discontinuation of antibiotic therapy. Continuous monitoring of electrolyte levels and renal function during colistin treatment is crucial.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 5","pages":"922-928"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Evaluation of bone health in transgender people. Position of the Argentine Osteoporosis Society]. [变性人骨骼健康评估。阿根廷骨质疏松症协会的立场]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Alberto Nagelberg, Rubén Abdala, María S Larroudé, Vanina Farías, Mariano Garabito, María C Balonga, Evangelina Giacoia, Silvia Karlsbrum, María M Pavlove, Adriana Frigeri, Mirena Buttazzoni, Pablo Costanzo, Sebastián Suarez, Andrés De Benito, Veronica Pappalardo, Mónica Drnovsek, Patricia San Martin, Cecilia Calvar, Adrian Helien

引用次数: 0

[Bazex syndrome: a rare paraneoplastic disease]. [巴泽克斯综合征：一种罕见的副肿瘤性疾病]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Anamá Di Prinzio, Ana C Torre, Susana E Perez Rios, Luis D Mazzuoccolo

引用次数: 0

[I have Parkinson's, what now?] [我有帕金森症，现在怎么办？]

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Daniel Manigot

引用次数: 0

Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic. COVID-19 大流行期间地方性人类冠状病毒感染的特征。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk

{"title":"Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic.","authors":"Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: After the implementation of mitigation strategies during the COVID-19 pandemic, the incidence of respiratory viruses, including human coronaviruses (HCoV), experienced a significant decrease. The aim of this study is to characterize the epidemiology and clinical aspects of HCoV infections in ambulatory adults during COVID-19 pandemic times.Methods: descriptive, prospective, longitudinal study performed in a private hospital in La Plata, Buenos Aires, Argentina between November 2020 and October 2022; 458 outpatient adults with upper respiratory tract infections (URTI) were studied undergoing clinical and microbiological follow-up.Results: 44 (9.6%) subjects were positive by multiplex PCR for HCoV. 14 of them for 229E (31.8%), 13 for OC43 (29.5%), 11 for HKU-1 (25.1%) and 6 for NL63 (13.6%). A repeated PCR was positive for the same HCoV in 19 (57%) of 33 patients on day 3-5. No hospitalizations or deaths were reported.Discussion: Endemic HCoV caused a significant proportion of URTI among outpatient adults during COVID-19-related restrictions times. An alternating pattern of circulation between alfa-HCoV and beta-HCoV was observed.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"102-107"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Dengue in Argentina and current strategies for its control]. [阿根廷的登革热及其控制策略]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Isabel N Kantor

引用次数: 0

[Observations on the dengue vaccination strategy in Argentina]. [阿根廷登革热疫苗接种策略观察]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Pablo Orellano, Dario Vezzani

{"title":"[Observations on the dengue vaccination strategy in Argentina].","authors":"Pablo Orellano, Dario Vezzani","doi":"","DOIUrl":"","url":null,"abstract":"A new dengue vaccine has recently been licensed in Argentina, with the Argentine government planning to acquire it in order to develop a vaccination strategy. As the disease is gradually following a path to endemicity in some regions of the country, the incorporation of these vaccines will have the potential to tackle the growing incidence of the disease and to reduce the disease burden. However, the establishment of the vaccination programme may also be susceptible of threats related to the epidemiological shift of the disease. Selecting a specific age group for the vaccine may result in a change in the peak incidence to other age groups more susceptible to severe forms of the disease, such as children or the elderly. Furthermore, the perception of protection following vaccine introduction in one jurisdiction may reduce adherence to vector control activities, increasing the risk of virus introduction and transmission in other areas not prioritised by the vaccination strategy, and the risk of other arboviral diseases such as Zika and chikungunya fever. These and other potential limitations to be considered prior to the implementation of vaccination programmes are discussed in this article, with a series of recommendations on how to address these concerns. These recommendations can help decision makers and public health practitioners at this early stage of the vaccination programme development.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"734-740"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Therapeutic monitoring of itraconazole in patients with chronic pulmonary aspergillosis: a possible solution to a frequent problem]. [慢性肺曲霉菌病患者伊曲康唑的治疗监测：一个常见问题的可能解决方案]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Florencia Capaccioli, Fernando Messina, Gabriela Santiso, Emmanuel Marin, Mercedes Romero, Christian Höcht, Javier Opezzo, Facundo Bertera

{"title":"[Therapeutic monitoring of itraconazole in patients with chronic pulmonary aspergillosis: a possible solution to a frequent problem].","authors":"Florencia Capaccioli, Fernando Messina, Gabriela Santiso, Emmanuel Marin, Mercedes Romero, Christian Höcht, Javier Opezzo, Facundo Bertera","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Chronic pulmonary aspergillosis is a fungal disease that, without specific treatment, generates a slow and progressive destruction of the lung parenchyma. The recommended pharmacological therapy is long-term oral antifungal administration. The efficacy of the treatment (especially with itraconazole) is around 65% and the frequency of recurrences 10-15%. One of the causes could be a deficient plasma level of itraconazole. The objective was to implement therapeutic monitoring (TM) of itraconazole using a sensitive, precise, rapid and reproducible method. Then, based to the results obtained, take a therapeutic approach.Materials and methods: Two venous blood samples of approximately 2 ml were obtained from each patient, which were analyzed by liquid chromatography (HPLC).Results: Samples were taken from 36 patients and mycological, antibody and MT of itraconazole studies were performed. A total of 10 patients (27.8 %) showed levels outside the therapeutic range.Discussion: The TM of itraconazole is a useful tool to improve the effectiveness of chronic pulmonary aspergillosis treatment, the prognosis of the pathology and reduce the percentage of recurrences. The developed method is fast, precise and reproducible, for this reason it can be very useful to be applied in the public hospital setting, where there is precisely no similar one, and thus modify therapeutic behaviors in order to optimize treatments.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 6","pages":"1110-1115"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0