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[Decreased vision due to hypovitaminosis A in children with food selectivity]. [有食物选择性的儿童因维生素 A 不足而导致视力下降]。
IF 0.6 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Natalia Moreno, Florencia C Lynch, María A Zalazar, Carla F Miranda, Sofía H Vidal, Marisa L Armeno
{"title":"[Decreased vision due to hypovitaminosis A in children with food selectivity].","authors":"Natalia Moreno, Florencia C Lynch, María A Zalazar, Carla F Miranda, Sofía H Vidal, Marisa L Armeno","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Vitamin A deficiency can cause eye disease and has been related to food selectivity in children with autism spectrum disorder (ASD).</p><p><strong>Methods: </strong>A series of 13 pediatric patients with severe ophthalmological involvement as an initial manifestation of hypovitaminosis A is described.</p><p><strong>Results: </strong>With significant Vitamin A deficiency, neuroimaging was performed in 11 patients. Of these, 8 had pathological findings with the presence of cranial hyperostosis. Lumbar puncture was performed in these patients and endocranial hypertension was detected in 7 of the 8 patients. All had food selectivity and 61.5% had ASD.</p><p><strong>Conclusions: </strong>Toxic-nutritional optic neuropathy is a rare pathology in children and presents with progressive, bilateral and painless visual loss due to damage to the optic nerve, which can generate severe and irreversible damage to it. Food history allows early detection of nutrient deficiencies in children with restrictive feeding, especially in neuro-atypical patients. This is essential to implement preventive measures and treatment with vitamin A in order to avoid irreversible consequences.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 5","pages":"860-867"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic autoinflammatory disease, IgA glomerulonephritis and renal cortical necrosis: coincidence or causation? 系统性自身炎症、IgA 肾小球肾炎和肾皮质坏死：巧合还是因果关系？
IF 0.6 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Carlos Chiurchiu, Pehuén Fernández, Walter Douthat, Javier De Arteaga, Marco Mazzotta, Maximiliano Alderete, Verónica Saurit, Francisco Caeiro, Jorge De La Fuente
{"title":"Systemic autoinflammatory disease, IgA glomerulonephritis and renal cortical necrosis: coincidence or causation?","authors":"Carlos Chiurchiu, Pehuén Fernández, Walter Douthat, Javier De Arteaga, Marco Mazzotta, Maximiliano Alderete, Verónica Saurit, Francisco Caeiro, Jorge De La Fuente","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present a patient with a rare systemic autoinflammatory disease (mevalonate kinase deficiency -MKD-) with the identification of two heterozygous variants (c.1129G>A and c.32C>T) in the Mevalonate Kinase gene, detected by next generation sequencing and a highly prevalent glomerulonephritis (IgA nephropathy). The patient presents clinically with a monthly recurrent periodic fever from 12 days of age, accompanied by mucocutaneous lesions (maculopapular rash in extremities, aphthous stomatitis), joint (arthralgias in ankles, wrists and knees), lymphoid (cervical lymphadenopathy, splenomegaly), gastrointestinal (diarrhea, abdominal pain) and kidney (hematuria and proteinuria) with repeated biopsies showing IgA nephropathy alternating activity with chronicity. During follow-up. The patients presented a poor therapeutic response to multiple immunosuppressive regimens used for 7 years (corticosteroids, azathioprine, mycophenolate, cyclophosphamide, rituximab and tocilizumab), and finally a good response to canakinumab. Four years after starting canakinumab, during the course of an infection due to a muscle abscess, the clinical presentation is complicated by a severe renal microvascular event (renal cortical necrosis -RCN-) with acute kidney injury and dialysis requirement. Therecurrent episodes of inflammation due to MKD could act as triggers for the reactivation of glomerulonephritis (which would explain the poor response to immunosuppressants and the rapid progression to histological chronicity) and to generate a microenvironment that predisposes the development of RCN in the face of a non-serious infection. A defect in IgA molecules has been described in MKD, a phenomenon also observed in IgA nephropathy. This raises the challenging hypothesis of a common pathogenetic link between all the patient's clinical manifestations.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"774-779"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mees lines associated with chemotherapy]. [与化疗有关的梅氏线]。
IF 0.6 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Daniel J Padilla Salcedo, Matías Carreras, Debora Pellegrini
{"title":"[Mees lines associated with chemotherapy].","authors":"Daniel J Padilla Salcedo, Matías Carreras, Debora Pellegrini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"794"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Raúl Carrea. A restless spirit. A tireless doer]. [劳尔-卡雷亚，永不停息的精神，孜孜不倦的实践者]。
IF 0.6 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Basilio A Kotsias
{"title":"[Raúl Carrea. A restless spirit. A tireless doer].","authors":"Basilio A Kotsias","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"809-810"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of long COVID in health personnel: comparing gender and work factors. 医务人员长期 COVID 分析：比较性别和工作因素。
IF 0.6 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Carlos Tajer, María José Martínez, Cecilia Straw, Débora Tajer, Manuel Riveiro, Laura Antonietti
{"title":"Analysis of long COVID in health personnel: comparing gender and work factors.","authors":"Carlos Tajer, María José Martínez, Cecilia Straw, Débora Tajer, Manuel Riveiro, Laura Antonietti","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to describe the reported prevalence of post-COVID-19 syndrome and its characteristics by gender, profession, and other determinants among health care workers.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among health workers with a history of COVID-19 in Latin America, and the 2030 responses from Argentina were selected for this analysis. Sociodemographic information, as well as data on initial course of COVID-19, and the persistence of 21 symptoms beyond the first month, their severity, clinical evolution, and health care demands were collected.</p><p><strong>Results: </strong>The reported prevalence of post-COVID-19 syndrome was higher in women for each of the symptom clusters studied. Severity of the initial symptoms, female gender, nursing profession, multi-employment, and working in emergency areas were all independent variables.</p><p><strong>Discussion: </strong>The greater strain of health care workers during the pandemic -highly feminized- and the associated gender conditions may partially explain these findings.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"605-618"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Anterior medullary infarction after procedure]. [手术后前髓梗塞]。
IF 0.8 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Ignacio Saguier Padilla, Irene De La Vega Vedoya, Silvia Folgar, Flavio Mercado
{"title":"[Anterior medullary infarction after procedure].","authors":"Ignacio Saguier Padilla, Irene De La Vega Vedoya, Silvia Folgar, Flavio Mercado","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"183"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acute cholangitis due to Candida glabrata and Klebsiella pneumoniae]. [念珠菌和肺炎克雷伯菌引起的急性胆管炎]。
IF 0.8 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
María Vanesa Durán, Romina V Viceconte, Ayelén La Torre
{"title":"[Acute cholangitis due to Candida glabrata and Klebsiella pneumoniae].","authors":"María Vanesa Durán, Romina V Viceconte, Ayelén La Torre","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute cholangitis is a bile duct infection associated with bile duct obstruction. Bile culture is positive in most cases, and the most frequent etiological agent is Escherichia coli. Candida sp acute cholangitis is a rare finding, which is more common in patients with immunosuppression, use of corticosteroids, prolonged antibiotic treatment or surgical procedures of the bile duct. We present the case of a 67-year-old woman with none of the above-mentioned history who consulted for fever, abdominal pain and jaundice. MRI of the abdomen revealed a lithiasic image in the common bile duct with dilation. It required endoscopic drainage of the biliary tract. Direct microscopic examination of the bile fluid revealed gram-negative bacilli and yeast, and in the culture of bile fluid Klebsiella pneumoniae producing extended spectrum beta-lactamase (ESBL) and Candida glabrata were isolated. The patient completed the antibiotic treatment with piperacillin tazobactam and anidulafungin with good evolution. Bile duct infection by association of Gram-negative bacilli and Candida sp is a rare entity, more in patients without underlying diseases.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"168-170"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Basilar skull fracture. Two semiological signs to remember]. [基底颅骨骨折。］
IF 0.8 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Adolfo Savia, Luis Barraza, María Ortiz De Rozas, Emanuel Sabaris Di Lorenzo, Ágata Fernández, Ignacio Rossi, Federico De Nicola, Johnson Larosse, Juan Copacaba, Rommel Maldonado
{"title":"[Basilar skull fracture. Two semiological signs to remember].","authors":"Adolfo Savia, Luis Barraza, María Ortiz De Rozas, Emanuel Sabaris Di Lorenzo, Ágata Fernández, Ignacio Rossi, Federico De Nicola, Johnson Larosse, Juan Copacaba, Rommel Maldonado","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"184"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Frailtry syndrome in the elderly: primary care approach]. [老年人体弱综合征：初级保健方法]。
IF 0.8 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Viviana A Londoño-Morales, Heider Bautista-Mier, Jheyson Parra-Saldarriaga, Jorge A Sánchez-Duque
{"title":"[Frailtry syndrome in the elderly: primary care approach].","authors":"Viviana A Londoño-Morales, Heider Bautista-Mier, Jheyson Parra-Saldarriaga, Jorge A Sánchez-Duque","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"179-182"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Geographic variability, health inequities and lethality due to COVID-19 in Bariloche, Río Negro, 2020-2021]. [2020-2021年巴里洛切、里奥内格罗的COVID-19造成的地理变异、健康不平等和致死率]。
IF 0.8 4区 医学
Medicina-buenos Aires Pub Date : 2024-01-01
Fernando Tortosa, Fernando Perre, Gabriela Carrasco, Gonzalo De Lusarreta, Natalia Artola, Dana Prandi, Rodrigo Bustamante, German Guaresti, Ariel Izcovich
{"title":"[Geographic variability, health inequities and lethality due to COVID-19 in Bariloche, Río Negro, 2020-2021].","authors":"Fernando Tortosa, Fernando Perre, Gabriela Carrasco, Gonzalo De Lusarreta, Natalia Artola, Dana Prandi, Rodrigo Bustamante, German Guaresti, Ariel Izcovich","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to analyze the geographic variability and the relationship between social determinants of health and COVID-19 lethality in Bariloche.</p><p><strong>Methods: </strong>A database from the National Epidemiological Surveillance System was used to analyze COVID-19 positive cases from January 2020 to December 2021. The data were geocoded and incorporated into a geographic information system (GIS). A three-step analytical framework was applied to measure health inequity, using socioeconomic indicators and access to services. A multivariate analysis was conducted to predict fatality.</p><p><strong>Results: </strong>A total of 25 020 COVID-19 cases were diagnosed in Bariloche during the study period. The fatality rate was 2.1%. Significant variability in socioeconomic indicators was observed among different territorial delegations of the city.</p><p><strong>Discussion: </strong>The results showed health inequities and an association between social determinants and COVID-19 lethality in Bariloche. Individuals living in areas with higher socioeconomic vulnerability had a higher risk of mortality. These findings highlight the importance of addressing health inequities in a pandemic response.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"29-46"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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