Medicina-buenos Aires最新文献_第9页

Analysis of long COVID in health personnel: comparing gender and work factors. 医务人员长期 COVID 分析：比较性别和工作因素。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Carlos Tajer, María José Martínez, Cecilia Straw, Débora Tajer, Manuel Riveiro, Laura Antonietti

引用次数: 0

[Effect of COVID-19 pandemics in treatment of cervical cancer: pre/post study]. [COVID-19大流行对宫颈癌治疗的影响：前后研究]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Silvina Arrossi, Fernando Binder, Carolina Ituarte, Natalia Martiarena, Alicia Campanera, Martín Bárcena, Melisa Paolino

{"title":"[Effect of COVID-19 pandemics in treatment of cervical cancer: pre/post study].","authors":"Silvina Arrossi, Fernando Binder, Carolina Ituarte, Natalia Martiarena, Alicia Campanera, Martín Bárcena, Melisa Paolino","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Little evidence exists on the impact of the COVID-19 pandemics on the compliance with cervical cancer treatment.Methods: We carried out a population-based, before-and-after retrospective cohort study of all cervical cancer patients diagnosed in the Jujuy province public health sector (n=140), Argentina, between 2017 and 2020. Patients diagnosed in 2020 were considered exposed to the COVID-19 pandemic (n=21). We used multivariable logistic regression to assess the relationship between the pandemics and compliance with treatment. We also measured treatment duration for women who were indicated brachytherapy and time to treatment initiation by stage.Results: Compared with women diagnosed in 2017-2019 the odds ratio of non-complying with treatment was 1.77 (95%CI 0.59-5.81; p = 0.32) for women diagnosed during 2020. An increased risk of non-compliance was found in patients with prescribed brachytherapy (OR 4.14. 95%CI 1.95-9.11; p < 0.001). Median treatment duration for women with prescribed brachytherapy was 12.8 and 15.7 weeks in 2017-2019 vs. 2020 (p = 0.33); median time to treatment initiation for women with early-stage disease was 9 and 5 weeks during 2017-2019 and 2020 respectively (p = 0.06), vs 7.2 and 9 weeks in 2017-2019 and 2020 respectively (p = 0.36) for patients with stages IIB+ disease.Conclusions: Low access to brachytherapy was a major determinant of non-compliance. irrespective of the effect of the pandemics.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Mees lines associated with chemotherapy]. [与化疗有关的梅氏线]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Daniel J Padilla Salcedo, Matías Carreras, Debora Pellegrini

引用次数: 0

[Immunogenicity and adverse events of SARS-CoV-2 vaccine in health workers]. [卫生工作者接种 SARS-CoV-2 疫苗的免疫原性和不良反应]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Vicente Juárez, Gabriela Marina, Claudia Ramón, Mariangeles Parentis, Lorena Mamaní, Gustavo A Rúa, Maria E Crespo Espindola, Emilio A Buschiazzo, Mariana M Aciar, Leila N Belbruno, María B Lecumberri, Ana C Ralle, Juan M Luna Murillo, Lucía Delgado, Ivanna Miranda Cáceres, Juan P Bonnal, Valeria E Guzman, Bernardo A Eddelcop

{"title":"[Immunogenicity and adverse events of SARS-CoV-2 vaccine in health workers].","authors":"Vicente Juárez, Gabriela Marina, Claudia Ramón, Mariangeles Parentis, Lorena Mamaní, Gustavo A Rúa, Maria E Crespo Espindola, Emilio A Buschiazzo, Mariana M Aciar, Leila N Belbruno, María B Lecumberri, Ana C Ralle, Juan M Luna Murillo, Lucía Delgado, Ivanna Miranda Cáceres, Juan P Bonnal, Valeria E Guzman, Bernardo A Eddelcop","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The aim of this study was to evaluate the adverse effects and immune response associated with IgG anti S1 SAEA-CoV-2 antibodies among healthcare workers at Señor del Milagro Hospital in Salta city, after receiving two doses of COVID-19 vaccine.Methods: A prospective cohort study was carried out from March 2021 to April 2022. Demographic, clinical data, adverse events supposedly attributed to vaccination (AEFIs) were collected and two samples were taken to measure serum antibody levels.Results: 408 volunteers participated, 401 (98%) were vaccinated with Sputnik-V. The average age was 45.5 years with a predominance of the female sex (71%). AEFIs were reported in 188 (46.1%) and 121 (29.7%) after the first and second doses respectively (p<0.001). These events were mostly mild and transient, more frequent after the first dose. The first antibody test was positive in 99% with a mean titer of 9.7 (SD 3.7). The second dosage was positive in 88% with a mean titer of 6.4 (SD 4.4). Participants with a history of infection and previous positive testing showed significantly higher antibody titers (p<0.001).Conclusion: The AEFIs reported were mostly mild and transient. Mass vaccination and administration of the recommended dose are essential to achieve effective herd immunity. The majority of vaccinated healthcare workers developed antibodies and those who had the disease prior to vaccination had significant antibody titers.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Atypical clinical presentation of chikungunya fever in critical care]. [重症监护中基孔肯雅热的非典型临床表现]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Yesica Lamberto, Pablo Saul, Susana Caceres, Milagro Sánchez Cunto, Viviana Chediack, Eleonora Cunto

{"title":"[Atypical clinical presentation of chikungunya fever in critical care].","authors":"Yesica Lamberto, Pablo Saul, Susana Caceres, Milagro Sánchez Cunto, Viviana Chediack, Eleonora Cunto","doi":"","DOIUrl":"","url":null,"abstract":"Chikungunya virus is an Alphavirus, it belongs to the family Togaviridae and is transmitted by mosquitoes. It was first described during an outbreak in Southern Tanzania in 1952. It generally causes a febrile syndrome, accompanied by joint pain and arthritis, which is often debilitating and may persist for months or years. Its overall fatality rate is not high, around 0.1%. Atypical and severe cases have been reported. This virus has been detected in more than 110 countries globally. In Northeastern Brazil autochthonous cases have been diagnosed since September 2014. In Argentina, as well as in neighboring countries, cases were increasing during 2023, compared to the same periods in previous years. Until epidemiological week 26 of 2023, 1460 cases of chikungunya fever were reported in Argentina, 72% of them were considered of autochthonous transmission. The case of a 76-year-old female patient is here presented, her comorbidities were hypertension and aortic stenosis, who was admitted to intensive care unit due to septic shock with respiratory focus, interstitial pneumonia in X-ray pattern, and torpid evolution. She died within 24 hours of admission. A report of detectable Chikungunya virus by real-time polymerase chain reaction in real time was received post-mortem. This case results of clinical relevance due to its atypical presentation and the country low prevalence of severe infections by this virus. It warns of the need to include the differential diagnosis in cases with suspected diagnosis.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Subacute ataxia associated with cerebellar ataxia, neuropathy and vestibular areflexia (CANVAS)]. [亚急性共济失调伴有小脑共济失调、神经病变和前庭反射障碍（CANVAS）]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Darío A Yacovino, Alan Gomez, María Belén Mayer, Fabián Fay

{"title":"[Subacute ataxia associated with cerebellar ataxia, neuropathy and vestibular areflexia (CANVAS)].","authors":"Darío A Yacovino, Alan Gomez, María Belén Mayer, Fabián Fay","doi":"","DOIUrl":"","url":null,"abstract":"Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS) is a late onset neurodegenerative disorder. Its genetic basis has recently been identified in the gene encoding a subunit of the Replication Factor C (RFC1). We present the case of a 62-year-old woman who experienced a history of a biphasic presentation of imbalance and gait disorders, with rapid onset of symptoms followed by slow and progressive neurological deterioration. The diagnostic process was challenging, and numerous tests were conducted to rule out acquired and genetic causes of ataxia, leading to a diagnosis of late-onset idiopathic cerebellar ataxia. Subsequently, vestibular function tests identified severe bilateral vestibulopathy. This led to considering CANVAS among the diagnoses, which was ultimately confirmed through genetic testing (biallelic expansion of the pentanucleotide AAGGG in the RFC1 gene). This case highlights the importance of this new described genetic disease and its subacute presentation variant, emphasizing the relevance of objective vestibular function tests in idiopathic ataxias to achieve proper diagnosis and eventual genetic counseling for offspring.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Use and impact of artificial intelligence in medicinal chemistry]. [人工智能在药物化学中的应用和影响]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Sebastián A Correa

引用次数: 0

Tracheobronchial jaundice. 气管支气管黄疸。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Indalecio Carboni Bisso, Leiniker Navarro Rey, Julieta González Anaya, Ignacio Fernández Ceballos, Marcos Las Heras

引用次数: 0

[Effectiveness of strategies to increase adherence to colorectal cancer screening: a systematic review]. [提高大肠癌筛查依从性策略的有效性：系统综述]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Iñaki M Dopazo Danieli, Manuel Robles, María Belén Bellando, Gonzalo Picardi, Yamila Schenfeld, Ariana Bruzzone, María Eugenia Esandi

{"title":"[Effectiveness of strategies to increase adherence to colorectal cancer screening: a systematic review].","authors":"Iñaki M Dopazo Danieli, Manuel Robles, María Belén Bellando, Gonzalo Picardi, Yamila Schenfeld, Ariana Bruzzone, María Eugenia Esandi","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Coverage for colorectal cancer screening in Argentina is very low. The objective of this review is to assess and synthesize the evidence on the effectiveness of strategies aimed at increasing adherence to colorectal cancer screening among healthcare personnel and the general population at average risk.Methods: A review of systematic reviews (SRs) that evaluated the effectiveness of these strategies was conducted. Searches were performed in electronic databases, meta-search engines, the Cochrane Library, and through manual searching. Eligibility and inclusion criteria were applied, with assessment of the quality of the SRs using AMSTAR II and the certainty of evidence using the GRADE approach. Thematic synthesis was conducted based on the taxonomy of strategies proposed by Dougherty (patient/community-targeted, professionaltargeted, and other types of strategies).Results: A total of 635 studies were identified, with 36 deemed eligible and 11 excluded due to insufficient quality, resulting in the inclusion of 10 SRs. A multiplicity of strategies with varying effectiveness were identified, with the majority targeting the population. Among these, education, self-testing with specimen collection at specific locations, and reminders stood out. For professionals, only education and reminders showed effectiveness. Combined strategies demonstrated greater effectiveness than isolated strategies.Conclusions: There is more evidence on strategies targeting the population than professionals. Combined strategies showed greater effectiveness, highlighting the need to explore barriers in both the population and professionals in each specific context in order to prioritize and combine those that have proven effective and would have a greater impact.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Muscle spasms and hypoesthesia in the lower limbs associated with optic neuritis]. [与视神经炎有关的下肢肌肉痉挛和感觉减退]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Lucas G De Feo

引用次数: 0