Medicina-buenos Aires最新文献_第9页

[Prevalence, phenotype distribution and cardiometabolic risk of polycystic ovarian syndrome in transgender population]. [跨性别人群多囊卵巢综合征患病率、表型分布及心脏代谢风险分析]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Cecilia E Calvar, Milagros Di Noto, Mayra Lema Villacis, Natalia Blanco Hirota, María Isabel Anticona Sayán

{"title":"[Prevalence, phenotype distribution and cardiometabolic risk of polycystic ovarian syndrome in transgender population].","authors":"Cecilia E Calvar, Milagros Di Noto, Mayra Lema Villacis, Natalia Blanco Hirota, María Isabel Anticona Sayán","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The prevalence of polycystic ovary syndrome (PCOS) in transgender and non-binary genders assigned female at birth (TMNBG) men is controversial. Our objectives were to investigate the prevalence, phenotypic characteristics of PCOS, and cardiometabolic risk of TMNBG with and without PCOS prior to hormone therapy.Materials and methods: This was a retrospective study of 346 TMNBG adults presenting to our service for gender-affirming hormone therapy. PCOS was diagnosed according to the evidence-based international guideline for the evaluation and treatment of PCOS 2018 and the Rotterdam consensus of 2003.Results: The described transgender population had a prevalence of PCOS of 23.8%. Phenotype B was the most common one (39.1%), followed by phenotype A (33.7%). Transgender people with PCOS had statistically higher body mass index (BMI), systolic and diastolic blood pressure, plasma insulin levels, HOMA-IR, and HOMA-B than those who did not meet PCOS criteria. However, blood pressure and markers of insulin resistance were similar for both groups after controlling for BMI.Discussion: PCOS appears to be prevalent among TMNBG. Transgender people with PCOS may exhibit an unfavorable cardiometabolic risk profile compared to those without PCOS, especially due to a higher BMI. It is necessary to evaluate the specific components of PCOS before starting hormonal therapy due to the long-term implications it could have.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 1","pages":"31-38"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Novel mutations in the calcium-sensing receptor encoding genes as a cause of familial hypocalciuric hypercalcemia]. [钙敏感受体编码基因的新突变是家族性低钙高钙血症的原因]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Marcelo Sarli, Elbio Genovesi, Luciana Levi, Damián Robbiani

引用次数: 0

Pseudomembranous Aspergillus fumigatus tracheobronchitis.

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

M Florencia Courtois, Indalecio Carboni Bisso, Ignacio Fernández Ceballos, Marcos Las Heras

引用次数: 0

[Emphysematous gastritis with portal pneumatosis in a patient with distal esophageal cancer]. [食管癌远端并发肺气肿性胃炎合并门脉气积1例]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

M Dolores Silveyra, Valentín Jarach, Luz Fernández Ugarte, Silvia Hernández, Paola Finocchietto, Diego Carrozza, Damián Contardo

引用次数: 0

[To leave the WHO: a decision that puts Argentine Public Health at risk]. [离开世卫组织：一个将阿根廷公共卫生置于危险境地的决定]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

引用次数: 0

Assessment of iodine intake in rural schoolchildren from La Pampa, Argentina: a comparative analysis between 2002 and 2023. 阿根廷拉潘帕农村学童碘摄入量评估：2002年至2023年的比较分析

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Jorge L Olivares, María Del Carmen Silva Croome, María Julia Gutierrez, Fany Arrese, Marina Villarreal, Luis A Ramírez Stieben

{"title":"Assessment of iodine intake in rural schoolchildren from La Pampa, Argentina: a comparative analysis between 2002 and 2023.","authors":"Jorge L Olivares, María Del Carmen Silva Croome, María Julia Gutierrez, Fany Arrese, Marina Villarreal, Luis A Ramírez Stieben","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Iodine is an essential micronutrient for the synthesis of thyroid hormones, crucial for neurological development. In 2002, a mild iodine deficiency was identified in schoolchildren from La Pampa, Argentina. This study aims to reassess iodine intake in the same rural school population in 2023 by analyzing urinary iodine concentration (UIC), goiter prevalence, and salt iodization.Materials and methods: A cross-sectional study was conducted in 6- to 12-year-old schoolchildren from School No. 45 in Ataliva Roca, La Pampa. Parents provided informed consent. UIC, weight, height, blood pressure, and goiter were assessed. UIC was measured using the modified Sandell-Kolthoff method, and salt iodization was analyzed using sodium thiosulfate titration. The results were compared with those from 2002.Results: A total of 74 schoolchildren were evaluated in 2023. The median UIC was 145.45 υg/L, with 28.8% of students showing levels below 50 υg/L. Goiter prevalence was 21.6%, compared to 17.9% in 2002. In 85.5% of the salt samples, iodine levels were adequate. There were no statistically significant differences between the 2002 and 2023 cohorts in the prevalence of goiter or iodine fortification of salt.Discussion: Despite improvements in iodine intake since 2002, a considerable percentage of schoolchildren still show moderate iodine deficiency.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 2","pages":"314-321"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Klebsiella pneumoniae liver abscess syndrome: an emerging global disease]. [肺炎克雷伯菌肝脓肿综合征：一种新兴的全球性疾病]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Camila Alves, María Belén López, Anahí Ossio, Paula Zamorano, Ruben Solari, Julian García, Andrés Benchetrit

引用次数: 0

[Can changes in diastolic function be predicted according to risk factors?] 舒张功能的改变是否可以根据危险因素来预测？］

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Juan S Alvarado Giménez, Beder G Farez, Gustavo G Vega

{"title":"[Can changes in diastolic function be predicted according to risk factors?]","authors":"Juan S Alvarado Giménez, Beder G Farez, Gustavo G Vega","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Diastolic function has a dynamic behavior according to modifying factors. We describe the variables used in its assessment by echocardiography in different population groups of men and women to determine whether changes can be predicted according to their risk factors.Materials and methods: Observational and descriptive cross-sectional registry. A systematic collection of anthropometric characteristics, risk factors and specific echocardiographic variables of diastolic function was performed in an outpatient echocardiography laboratory. Quantitative variables were expressed as mean and standard deviation for Gaussian distribution variables. Discrete variables were analyzed using contingency tables, qualitative variables are expressed as percentages. Means were compared using the Student t test.Results: A total of 107 patients were admitted. Those with sedentary lifestyle had a mean left atrial volume of 29 ml/m2, a deceleration time of 218 ms, a transmittal flow ratio E/A (EA) of 1.5, tissue Doppler ratio Ee´ (Ee) of 6 and e´a´ (ea) of 1.4; those who performed physical activity 3 times a week were characterized by having a left atrial volume of 35 ml/m2, a deceleration time of 210 ms, EA of 1.8, Ee of 5 and ea of 1.8. Patients with obesity had a left atrial volume of 35 ml/m2, deceleration time of 226 ms, E/A 1.1, Ee of 9 and ea of 1.2. Those with arterial hypertension had a left atrial volume of 33 ml/m2, deceleration time of 224 ms and E/A ratio of 1, Ee of 8 and ea of 1.Discussion: The inclusion of certain risk factors in the history prior to echocardiographic evaluation can predict subgroups with different diastolic function.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 1","pages":"23-30"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Myositis secondary to all-transretinoic acid during induction in acute promyelocytic leukemia]. [急性早幼粒细胞白血病诱导过程中全转维甲酸继发的肌炎]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Cristian L Rodríguez, Martín Milanesio, Ana R Montivero, María B Castro, Ana L Basquiera

{"title":"[Myositis secondary to all-transretinoic acid during induction in acute promyelocytic leukemia].","authors":"Cristian L Rodríguez, Martín Milanesio, Ana R Montivero, María B Castro, Ana L Basquiera","doi":"","DOIUrl":"","url":null,"abstract":"Acute promyelocytic leukemia (APL) is a specific subtype of acute myeloid leukemia (AML) characterized by the presence of the 15;17 translocation, that generates the PML/RARalpha fusion gene. First-line induction treatment includes the combination of all-transretinoic acid (ATRA) and arsenic trioxide, with which complete response rates greater than 90% are achieved. Although the combination is very effective, there are adverse reactions associated with the treatment, which include cellular differentiation syndrome, headache, fatigue, elevated triglycerides, and myositis. The latter is rare and is manifested by intense muscle pain a few days after starting ATRA. Creatine phosphokinase (CPK) values are not always elevated and this can make diagnosis difficult with delayed treatment and increased risk of complications. We report the case of a woman with APL who, during the induction phase of treatment, presented myositis of the pelvic muscles and lower extremities secondary to the administration of ATRA. The condition resolved after the administration of corticosteroids and temporary suspension of ATRA, with no recurrence after its restart.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 2","pages":"449-453"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaccination in adults: practical strategies to promote adherence. 成人疫苗接种：促进依从性的实用策略。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

María Natalia Nachón, Matías Mirofsky, María Vanesa Durán, Adolfo Savia, Alejandra Rosas, Sergio Zunino, Luis Cámera, Raul Ledesma, Hugo Milione, Pascual Valdez

引用次数: 0