Medicina-buenos Aires最新文献_第9页

[Primary hepatic sarcomatoid carcinoma, an unusual case]. [原发性肝肉瘤样癌，一个不寻常的病例]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Darío A Rueda, Florencia Antinucci, Marcelo F Amante, Carlos A Bas

引用次数: 0

[Abscessed tuberculomas in immunocompetent patient]. [免疫功能正常患者的脓毒性结核瘤]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

María Victoria Perez Allub, Cinthya Reznik, Ignacio Saguier Padilla, Alberto R Aguirre, Silvia S Folgar, Flavio C B Mercado

引用次数: 0

[Brush migration in a tracheostomized patient]. [气管插管病人的刷子移位]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Hugo Paez Pastor, Juan Rouquaud, Artemio Garcia, Julieta Franzoy, Pablo Young

引用次数: 0

[Intestinal pneumatosis and pneumoperitonum: not always a surgical indication]. [肠积气和腹腔积气：不一定是手术指征]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Julio César Rotondaro, Manuel Maya, Magalí Gutierrez, Gonzalo L Echavarria, Gustavo H Badariotti

{"title":"[Intestinal pneumatosis and pneumoperitonum: not always a surgical indication].","authors":"Julio César Rotondaro, Manuel Maya, Magalí Gutierrez, Gonzalo L Echavarria, Gustavo H Badariotti","doi":"","DOIUrl":"","url":null,"abstract":"Pneumatosis intestinalis and pneumoperitoneum are not pathological entities in themselves, they are radiological signs that result from some underlying condition. In general, these are associated with serious intra-abdominal processes that result in emergency surgeries with bowel resections. Below, we present the case of an 80-year-old woman, diagnosed with stage IV breast cancer under treatment with fulvestrant and ribociclib, who was admitted to our center due to abdominal pain and vomiting. She was diagnosed with intestinal pneumatosis and pneumoperitoneum, so she underwent exploratory laparotomy for suspected intestinal ischemia. There was no evidence of intestinal necrosis or perforation, so resection was not performed. She progressed satisfactorily during hospitalization and in the tomographic control one month after discharge there was complete resolution of the condition. Although this condition has been described in relation to episodes of increased intra-abdominal pressure, such as emesis, it has also been described in patients with neoplasms, mainly of the digestive tract, either due to local damage or toxicity associated with chemotherapy. We found no reports in the literature of pneumatosis intestinalis linked to this antineoplastic medication in humans. Probably in our case the etiology was multifactorial. It is possible that ribociclib played a role, either through an indirect mechanism associated with vomiting and immunosuppression or directly on the enterocyte due to its non-specific cellular mechanism of action.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 3","pages":"574-578"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical predictor of volume hypoperfusion in patients treated with extended window mechanical thrombectomy: an external validation study. 延长窗机械取栓术患者容量灌注不足的临床预测因素：一项外部验证研究。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Santiago A Cutiller, Juan J Cirio, Celina Ciardi, Pedro Lylyk

{"title":"Clinical predictor of volume hypoperfusion in patients treated with extended window mechanical thrombectomy: an external validation study.","authors":"Santiago A Cutiller, Juan J Cirio, Celina Ciardi, Pedro Lylyk","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Treatment of ischemic stroke has expanded beyond the 6-hour window, but identification of eligible patients requires advanced imaging, which is often unavailable. This study aimed to validate a prediction model using the NIHSS score (a measure of stroke severity) to estimate hypoperfusion volume and determine eligibility for DEFUSE 3 treatment criteria.Materials and methods: Data from ischemic stroke patients with less than 24 hours' evolution were analyzed. A previously developed prediction rule based on the NIHSS score was used to estimate the volume of hypoperfused tissue with Tmax>6s, a marker for eligibility for the DEFUSE 3 treatment criteria. This estimated volume was compared with actual perfusion volumes obtained by magnetic resonance imaging or computed tomography with AI segmentation. Sensitivity, specificity and predictive values for determining DEFUSE 3 eligibility were calculated.Results: Sixty-one patients were included (age: 71.9 ± 14.8 years, female: 60%, NIHSS: 16.5 ± 7.4 points). The prediction rule showed high accuracy in determining DEFUSE 3 eligibility with a sensitivity of 0.96, specificity of 0.93, positive predictive value of 0.98 and negative predictive value of 0.87.Discussion: Estimating hypoperfusion volume directly from the NIHSS score using a simple prediction rule provides a reliable and readily available method for identifying patients potentially eligible for DEFUSE 3 treatment. Rapid and reliable estimation of hypoperfusion volume could improve access to advanced stroke care in settings with limited imaging resources.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 6","pages":"1071-1079"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Molecular diagnosis of bacteriaemia: benefits of using the FilmArray® BCID2 sepsis panel in a third level hospital]. [细菌血症的分子诊断：在一家三级医院使用 FilmArray® BCID2 败血症面板的益处]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Natalia A Díaz, Javier Farina, Liucó Zubeldía Brenner, Glenda Guzman, Sofía Lucini, Candela Serra, María Laura Negro, María Florencia Gil

{"title":"[Molecular diagnosis of bacteriaemia: benefits of using the FilmArray® BCID2 sepsis panel in a third level hospital].","authors":"Natalia A Díaz, Javier Farina, Liucó Zubeldía Brenner, Glenda Guzman, Sofía Lucini, Candela Serra, María Laura Negro, María Florencia Gil","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Delay in initiating appropriate antimicrobial therapy prolongs hospitalization, increases in-hospital mortality, and raises economic costs. Currently, the identification and susceptibility testing of bacteria in positive blood cultures require a considerable amount of time. The objective of this study was to assess the impact of the BCID2 FilmArray® (FA) panel on the timing of appropriate antimicrobial therapy and potential antimicrobial costs.Methods: This is a retrospective observational study focused on positive blood cultures in hospitalized patients. FA processing was conducted concurrently with routine sample processing. Changes in antibiotic treatments based on FA results were evaluated, and the reduction in antimicrobial therapy duration and associated cost savings were calculated.Results: Eighty-seven bacteremia episodes were analysed. In 42 (48%) of them antimicrobial therapy was de-escalated to narrower spectrum agents, while in 7 (8%) therapy was escalated to broader spectrum antimicrobials. Additionally, in 8 (9%) antimicrobials were switched without changing spectrum and in 30 (34%) no changes were made based on FA results. Antimicrobial changes were made 2.3 days faster than with routine sample processing resulting in calculated potential savings of US$ 7408.Conclusion: The implementation of FA facilitated a faster administration of appropriate antimicrobial therapy, leading to a reduction in the duration of broadspectrum empirical antimicrobial therapy and subsequent economic savings.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"649-655"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Lepromatous leprosy with respiratory failure in the City of Buenos Aires]. [布宜诺斯艾利斯市伴有呼吸衰竭的麻风病人]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Roberto A Villa

引用次数: 0

Acute pulmonary histoplasmosis. 急性肺组织胞浆菌病

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

M Florencia Courtois, Indalecio Carboni Bisso, María José Labanca, Ignacio Fernández Ceballos, Marcos Las Heras

引用次数: 0

Risk factors associated with invasive pulmonary aspergillosis in severe COVID-19 patients: a casecontrol study. 与严重 COVID-19 患者侵袭性肺部曲霉菌病相关的风险因素：一项病例对照研究。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Emilse D Díaz Lobo, Micaela Gomez Giglio, Emilio F Huaier Arriazu, Indalecio A Carboni Bisso, Marcos J Las Heras, María L Peroni

{"title":"Risk factors associated with invasive pulmonary aspergillosis in severe COVID-19 patients: a casecontrol study.","authors":"Emilse D Díaz Lobo, Micaela Gomez Giglio, Emilio F Huaier Arriazu, Indalecio A Carboni Bisso, Marcos J Las Heras, María L Peroni","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Since the onset of the COVID-19 pandemic, cases of COVID-19-associated pulmonary aspergillosis (CAPA) have been described. Possible risk factors for the development of this condition have been proposed, although evidence in Latin American populations is limited. The objectives were to identify risk factors for the development of CAPA and describe the characteristics of this infection.Materials and methods: A retrospective case-control study was conducted. The population consisted of adult patients with severe COVID-19, hospitalized in ICU and who had undergone diagnostic tests for invasive pulmonary aspergillosis.Results: Seventy-five patients were evaluated, 21 in the case group and 54 in the control group. 64% were male, with an average age of 62.7 years. It was found that a history of diabetes (OR 3.3, CI 1.09-9.95, p=0.03), smoking (OR 3.47, CI 1.20-10, p=0.02), coronary artery disease (OR 5, CI 1.24-20.08, p=0.02), and a Charlson score equal to or greater than 5 (OR 1.27, CI 1-1.60, p=0.013) could be associated with the development of CAPA. Most cases were considered as possible CAPA (87.5%). The time between orotracheal intubation to the diagnosis of CAPA was 11.5 days. Fever was the most common symptom (90%), and only 24% of patients had compatible radiographic findings. Mortality in the case group was 61.9%.Discussion: A history of diabetes, smoking, coronary artery disease, and a Charlson score equal to or greater than 5 may increase the risk of developing CAPA.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 6","pages":"1049-1060"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[High blood pressure and associated lifestyles in an urban population in Argentina]. [阿根廷城市人口的高血压和相关生活方式]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Mariana N Carrillo, Nancy Babio, Jesica Miño, Camila Niclis, Eugenia Haluszka, Stefano Staurini, Julia M Wirtz Baker, Lorena Viola, Sonia A Pou, Néstor H García, Sonia E Muñoz, Laura R Aballay

{"title":"[High blood pressure and associated lifestyles in an urban population in Argentina].","authors":"Mariana N Carrillo, Nancy Babio, Jesica Miño, Camila Niclis, Eugenia Haluszka, Stefano Staurini, Julia M Wirtz Baker, Lorena Viola, Sonia A Pou, Néstor H García, Sonia E Muñoz, Laura R Aballay","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The American Heart Association (AHA/ACC) sets as a goal for blood pressure (BP) control not to exceed values of 130/80 mmHg, both in individuals with and without a diagnosis of hypertension (HT), standards not evaluated so far in the Argentine population. The objective was to determine the prevalence of high BP (HBP) in individuals with and without a diagnosis of HT taking into account the AHA/ACC criteria and to evaluate its association with sociodemographic and lifestyle factors.Materials and methods: Cross-sectional populationbased study in 911 persons >18 years of age in Córdoba, Argentina (period 2020-2022). Sociodemographic and lifestyle data, history of HT, diabetes and medication use, anthropometric measurements, BP and dietary intake were collected. HBP was defined for systolic and/or diastolic BP ≥130 / ≥80mmHg, respectively at the time of measurement. The presence of HT was assessed by self-report and/or consumption of antihypertensive medication. The association of HBP with lifestyle was assessed using multiple logistic regression models.Results: 84.8% and 55.6% of the patients with and without hypertension had HBP, respectively. HBP was positively associated with age and BMI, the latter only in persons without HT (OR:1.10; 95%CI:1.06-1.14), while hours of sleep showed an inverse association (OR:0.63; 95%CI:0.45-0.88).Discussion: There is a high prevalence of HBP in the city of Córdoba, Argentina. It is of utmost importance and urgency to implement sanitary measures to control BP in order to avoid adverse health consequences.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 6","pages":"1146-1156"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0