Medicina-buenos Aires最新文献_第9页

[Evaluation of bone health in transgender people. Position of the Argentine Osteoporosis Society]. [变性人骨骼健康评估。阿根廷骨质疏松症协会的立场]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Alberto Nagelberg, Rubén Abdala, María S Larroudé, Vanina Farías, Mariano Garabito, María C Balonga, Evangelina Giacoia, Silvia Karlsbrum, María M Pavlove, Adriana Frigeri, Mirena Buttazzoni, Pablo Costanzo, Sebastián Suarez, Andrés De Benito, Veronica Pappalardo, Mónica Drnovsek, Patricia San Martin, Cecilia Calvar, Adrian Helien

引用次数: 0

[Bazex syndrome: a rare paraneoplastic disease]. [巴泽克斯综合征：一种罕见的副肿瘤性疾病]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Anamá Di Prinzio, Ana C Torre, Susana E Perez Rios, Luis D Mazzuoccolo

引用次数: 0

[I have Parkinson's, what now?] [我有帕金森症，现在怎么办？]

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Daniel Manigot

引用次数: 0

Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic. COVID-19 大流行期间地方性人类冠状病毒感染的特征。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk

{"title":"Characteristics of endemic human coronavirus infections during times of COVID-19 pandemic.","authors":"Eric E Crocci, Delfina Schreiner, Emilia A García, Esteban C Nannini, Manuela Cobos, Paula Doubik, Juan P Balbuena, Agustin Romandetta, Bettina Cooke, María F Alzogaray, Elsa Baumeister, Analia Mykietiuk","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: After the implementation of mitigation strategies during the COVID-19 pandemic, the incidence of respiratory viruses, including human coronaviruses (HCoV), experienced a significant decrease. The aim of this study is to characterize the epidemiology and clinical aspects of HCoV infections in ambulatory adults during COVID-19 pandemic times.Methods: descriptive, prospective, longitudinal study performed in a private hospital in La Plata, Buenos Aires, Argentina between November 2020 and October 2022; 458 outpatient adults with upper respiratory tract infections (URTI) were studied undergoing clinical and microbiological follow-up.Results: 44 (9.6%) subjects were positive by multiplex PCR for HCoV. 14 of them for 229E (31.8%), 13 for OC43 (29.5%), 11 for HKU-1 (25.1%) and 6 for NL63 (13.6%). A repeated PCR was positive for the same HCoV in 19 (57%) of 33 patients on day 3-5. No hospitalizations or deaths were reported.Discussion: Endemic HCoV caused a significant proportion of URTI among outpatient adults during COVID-19-related restrictions times. An alternating pattern of circulation between alfa-HCoV and beta-HCoV was observed.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 1","pages":"102-107"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139564449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Dengue in Argentina and current strategies for its control]. [阿根廷的登革热及其控制策略]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Isabel N Kantor

引用次数: 0

[Observations on the dengue vaccination strategy in Argentina]. [阿根廷登革热疫苗接种策略观察]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Pablo Orellano, Dario Vezzani

{"title":"[Observations on the dengue vaccination strategy in Argentina].","authors":"Pablo Orellano, Dario Vezzani","doi":"","DOIUrl":"","url":null,"abstract":"A new dengue vaccine has recently been licensed in Argentina, with the Argentine government planning to acquire it in order to develop a vaccination strategy. As the disease is gradually following a path to endemicity in some regions of the country, the incorporation of these vaccines will have the potential to tackle the growing incidence of the disease and to reduce the disease burden. However, the establishment of the vaccination programme may also be susceptible of threats related to the epidemiological shift of the disease. Selecting a specific age group for the vaccine may result in a change in the peak incidence to other age groups more susceptible to severe forms of the disease, such as children or the elderly. Furthermore, the perception of protection following vaccine introduction in one jurisdiction may reduce adherence to vector control activities, increasing the risk of virus introduction and transmission in other areas not prioritised by the vaccination strategy, and the risk of other arboviral diseases such as Zika and chikungunya fever. These and other potential limitations to be considered prior to the implementation of vaccination programmes are discussed in this article, with a series of recommendations on how to address these concerns. These recommendations can help decision makers and public health practitioners at this early stage of the vaccination programme development.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"734-740"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Perception and identification of barriers to the use of digital technologies in arterial hypertension]. [动脉高血压患者对数字技术使用障碍的认识和识别]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Rodrigo Sabio, Walter Espeche, Jessica Barochiner, Alejandro Díaz, Pedro Grosse, Roberto Flores, Roberto Parodi, José Romano, Alejandra Gaydou, Nicolas Renna

{"title":"[Perception and identification of barriers to the use of digital technologies in arterial hypertension].","authors":"Rodrigo Sabio, Walter Espeche, Jessica Barochiner, Alejandro Díaz, Pedro Grosse, Roberto Flores, Roberto Parodi, José Romano, Alejandra Gaydou, Nicolas Renna","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Electronic devices and communication technologies are increasingly used to provide medical care to patients with high blood pressure. The main objective was to evaluate doctors' perception on the usefulness of digital technologies in hypertension. The secondary objectives were to evaluate the prevalence of use of digital technologies in the follow-up of patients with hypertension and to identify the barriers perceived by doctors for their implementation in the Argentine Republic.Methods: Observational, cross-sectional, multicenter study, based on a self-administered questionnaire, in the Argentine Republic, and coordinated by the Epidemiology group of the Argentine Society of Arterial Hypertension.Population: Doctors who care for patients with high blood pressure.Results: 247 responses were obtained, 35.6% were women and 64.4% men; 92.3% indicated that the use of digital technologies was useful to improve therapeutic adherence; 54.7% received blood pressure results at home through some digital means; 41.3% regularly carry out teleconsultations, only 6.1% through specific digital health platforms, 29.1% through non-specific platforms, by telephone 21.9% and by email (asynchronous) 10.9%. The main perceived barriers were: availability, financial remuneration, regulations, connectivity problems and lack of time.Conclusion: The perception of professionals is favorable, as they considered these technologies useful to improve therapeutic adherence, which could have a facilitating effect on their implementation, although the perceived barriers are part of organizational issues to be resolved.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 4","pages":"629-634"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of sodium dichloroacetate for cancer treatment: a scoping review. 使用二氯乙酸钠治疗癌症：范围综述。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Cecilia Bianchi, Romina P Martinelli, Viviana R Rozados, O Graciela Scharovsky

{"title":"Use of sodium dichloroacetate for cancer treatment: a scoping review.","authors":"Cecilia Bianchi, Romina P Martinelli, Viviana R Rozados, O Graciela Scharovsky","doi":"","DOIUrl":"","url":null,"abstract":"In recent years, drug repurposing (DR) has gained significant attention as a promising strategy for identifying new therapeutic uses of existing drugs. One potential candidate for DR in cancer treatment is sodium dichloroacetate (DCA), which has been shown to alter tumor metabolism and decrease apoptosis resistance in cancer cells. In this paper, we present a scoping review of the use of DCA for cancer treatment in adult patients, aiming to identify key research gaps in this area. This scoping review aims to explore the existing scientific literature to provide an overview of the use of DCA (any dose, frequency, or route of administration) in adults with cancer. A comprehensive literature search of the medical databases MEDLINE/PubMed, LILACS, EPISTEMONIKOS, the Cochrane Library, and ClinicalTrials was performed. We included publications reporting on adult patients diagnosed with any type of cancer treated with sodium dichloroacetate in combination or not with other drugs. All types of study design were included. A total of 12 articles were included, most of them were case reports. We found a high degree of heterogeneity between them. The most frequent adverse events in the evaluated studies were asthenia, reversible toxicity, and an increase in liver enzymes. Effectiveness was difficult to evaluate. We conclude that there is insufficient evidence to affirm that treatment with DCA in cancer patients is effective or is safe.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 2","pages":"313-323"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering the causes of advanced-stage disease at diagnosis among breast cancer patients who attended a suburban hospital in Buenos Aires. 破解在布宜诺斯艾利斯郊区医院就诊的乳腺癌患者确诊时已是晚期的原因。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Marcela I Coianis, Leo Saldain, María Victoria Grandoni, Cecilia Surdo, Javier Burruchaga, Paula Martínez Vázquez, Andrea Donati, Nancy De Mori, Pedro L Casserly, Beatriz L Kennel, Eunice Spengler, Claudia Lanari, Caroline A Lamb

{"title":"Deciphering the causes of advanced-stage disease at diagnosis among breast cancer patients who attended a suburban hospital in Buenos Aires.","authors":"Marcela I Coianis, Leo Saldain, María Victoria Grandoni, Cecilia Surdo, Javier Burruchaga, Paula Martínez Vázquez, Andrea Donati, Nancy De Mori, Pedro L Casserly, Beatriz L Kennel, Eunice Spengler, Claudia Lanari, Caroline A Lamb","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Breast cancer is still one of the main causes of cancer mortality in women worldwide, and death rates are even greater in vulnerable populations. A delay in diagnosis usually comes with advanced-stage disease, which impacts patient survival. The aim of this study was to evaluate the time for first medical consultation among women with breast cancer attending the Magdalena V. de Martínez Hospital and to determine the causes that may influence patient delay and its impact on cancer stage at diagnosis.Materials and methods: Three hundred and six breast cancer patients were interviewed using a self-report questionnaire, and socioeconomic and demographic variables, namely, highest education level completed, employment status and breast cancer awareness, were collected. The answers were associated with patient clinical records, such as clinical staging and tumor size.Results: Forty-nine percent of the patients were diagnosed with advanced-stage disease. These women had either a deficiency in breast cancer awareness, did not visit a gynecologist after age 40 or, were unemployed, while those patients diagnosed with early-stage breast cancer had nonpalpable tumors, declared a sufficient household income or delayed less than four weeks in seeking medical attention. Moreover, the delay in the first medical visit was more than one month in 78% of the patients, being disregard the most common cause of postponement. Additionally, patient delays were associated with larger tumors and with incomplete education.Discussion: These results indicate that early detection efforts should be made to reduce the disease stage at diagnosis, which may impact on overall survival.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"84 5","pages":"811-822"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chikungunya: an emerging problem and an approved vaccine]. [基孔肯雅病：新出现的问题和已获批准的疫苗]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Isabel N Kantor

引用次数: 0