Medicina-buenos Aires最新文献

[Autism spectrum disorder: a functional approach to development]. [自闭症谱系障碍：发展的功能性方法]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Silvana B Napoli, María P Vitale, María G Urinovsky, Juan J López Luro, Bárbara Gouguenheim, María P Fassero, Juan P Molina, Lucía Bujan, Paula Pedernera Bradichansky, Celina Lejarraga, Emanuel Bellantonio, Anabella Escalante, María B Micheletti, Laura Rodriguez, Fernando Russo, José Argento, Nadia Wieczorko, Pablo Cafiero

{"title":"[Autism spectrum disorder: a functional approach to development].","authors":"Silvana B Napoli, María P Vitale, María G Urinovsky, Juan J López Luro, Bárbara Gouguenheim, María P Fassero, Juan P Molina, Lucía Bujan, Paula Pedernera Bradichansky, Celina Lejarraga, Emanuel Bellantonio, Anabella Escalante, María B Micheletti, Laura Rodriguez, Fernando Russo, José Argento, Nadia Wieczorko, Pablo Cafiero","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Children and adolescents with autism spectrum disorder (ASD) exhibit diverse functioning and share challenges in social communication and repetitive behaviors. Diagnostic classifications do not fully capture their daily strengths and limitations, making functional assessments essential. The International Classification of Functioning, Disability and Health (ICF) highlights activities and participation as fundamental aspects to describe health conditions. TEA-CIFunciona, an ICF based tool, standardizes functional assessment and defines intervention goals for children with ASD in Argentina. This study aims to: 1) describe the functioning of children with ASD across age-based groups and 2) compare functional needs and intervention goals within each subgroup.Materials and methods: TEA-CIFunciona was administered in follow-up consultations of children under 16 years of age with a confirmed ASD diagnosis, from 2019 to October 2024.Results: The functional profile of a sample of 497 children and adolescents was established. Functional categories (activities, participation and contextual factors) were compared between two age subgroups.Discussion: TEA-CIFunciona facilitated the functional assessment, the systematization of data collection necessary to adapt the follow-up of children and adolescents with ASD at national level. It also enabled the identification of individual and group intervention objectives.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 1","pages":"44-59"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental allergen exposure in patients with allergic rhinitis in Zhangjiagang: findings from a skin prick test study. 张家港地区变应性鼻炎患者环境变应原暴露：皮肤点刺试验研究结果

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Chen Chen, Li Menglin, Liu Jianyong, Ma Xingkai, Wu Geping

{"title":"Environmental allergen exposure in patients with allergic rhinitis in Zhangjiagang: findings from a skin prick test study.","authors":"Chen Chen, Li Menglin, Liu Jianyong, Ma Xingkai, Wu Geping","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This study aimed to identify the main allergens causing allergic rhinitis (AR) in Zhangjiagang and analyze their epidemiological features.Materials and methods: From July 2018 to June 2019, 1684 patients with suspected allergic rhinitis in the outpatient department of the First People's Hospital of Zhangjiagang City were tested with an allergen skin prick test (SPT) and statistically analyzed.Results: The overall SPT positive rate was 65.3%. House dust mites (56.2%) and dust mites (56.0%) were the predominant inhalant allergens. Inhalant allergen positivity (59.4%) significantly exceeded ingested allergens (3.4%). The positive rate of inhalation allergens was significantly higher than that of ingestion allergens (χ2=1224.83, p<0.05). There was no significant difference in SPT positive rate between males and females (χ2=1.342, p>0.05). Positivity rates declined with age. Seasonally, autumn showed the highest positivity (74.0%), followed by winter (69.3%), summer (64.6%), and spring (54.7%). Specific allergens like birch, willow, rapeseed, Chinese parasol, and ragweed peaked in autumn, while Alternaria alternata peaked in summer, and cockroach was higher in autumn/winter.Conslusion: House dust mites (56.2%) and dust mites (56.0%) are the predominant allergens triggering allergic rhinitis in Zhangjiagang's humid subtropical climate, with inhalant allergens (59.4%) significantly exceeding ingested allergens (3.4%). The distinct age-related decline in allergen positivity, higher cockroach sensitization in males compared to females, and seasonal variation with peak positivity in autumn (74.0%) collectively inform tailored prevention strategies and region-specific immunotherapy protocols for allergic rhinitis management in this region.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 1","pages":"73-83"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

["All I know is that I know nothing": a pedagogical foundation in medical and health sciences]. [“我所知道的就是我一无所知”：医学和健康科学的教学基础]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Sebastián A Correa

引用次数: 0

[Stephen Hales and the origins of hemodynamic monitoring]. [Stephen Hales和血液动力学监测的起源]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Eduardo Herrera-Aliaga, Manuel E Cortés

引用次数: 0

The "Coca-Cola bottle sign" in Graves' ophthalmopathy. 格雷夫斯眼病中的“可口可乐瓶标志”。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Gabriela Limeres Alvares, Márcio L Duarte, Mayara Oliveira Da Silva, Guilherme Gonçalves Comparini

引用次数: 0

Checkpoint inhibitor-related pneumonitis. 检查点抑制剂相关性肺炎。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Máximo Rousseau-Portalis, Indalecio Carboni Bisso

引用次数: 0

[Argentine National Immunization Commission: some reflections on recent changes]. [阿根廷国家免疫委员会：对最近变化的一些思考]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Daniel Stecher

引用次数: 0

Comparative analysis of procalcitonin kinetics between the first and second infectious events in the intensive care unit. 重症监护病房第一次和第二次感染事件降钙素原动力学的比较分析。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Eduardo M Prado, Jorge F Sinner, Joaquín Cantos, Nicolás Contrera Rolón, Indalecio Carboni Bisso, Ignacio Fernandez Ceballos, Mariana Vaena, Verónica Monzon, Iván A Huespe

{"title":"Comparative analysis of procalcitonin kinetics between the first and second infectious events in the intensive care unit.","authors":"Eduardo M Prado, Jorge F Sinner, Joaquín Cantos, Nicolás Contrera Rolón, Indalecio Carboni Bisso, Ignacio Fernandez Ceballos, Mariana Vaena, Verónica Monzon, Iván A Huespe","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Sepsis arises from a dysregulated host response to infection. After the initial hyperinflammatory phase, some patients may develop sepsis-induced immunosuppression, predisposing them to new infectious episodes whose immunological behavior remains poorly understood. Procalcitonin (PCT) is a widely used biomarker in sepsis management, but its kinetics during recurrent infections have not been systematically evaluated.Materials and methods: Retrospective cohort study at a tertiary university hospital in Argentina, including adult intensive care unit patients who experienced two infectious events separated by 7 to 30 days. PCT levels and SOFA scores were analyzed using mixed-effects models, adjusting for infection source, bacterial isolation, and renal function.Results: 55 patients met inclusion criteria. During the first infectious event, PCT levels were significantly higher: 42.13 pg/mL (95% CI 33.59-50.67) and showed a rapid daily decline of 5 pg/mL (95% CI -5.9 to -4; p<0.01). In contrast, the second event showed lower PCT peaks: 32.47 pg/mL (-9.66 pg/mL difference; p<0.01) and a slower decline (interaction coefficient 1.45; p=0.04). Organ dysfunction was greater during the first event, with higher delta SOFA scores compared to the second median 5 vs. 2 (coefficient -2.53; p<0.01).Conclusion: These findings show distinct PCT kinetics between initial and subsequent infectious episodes, suggesting attenuated inflammatory responses and reduced organ dysfunction during the second event. The observed alteration in PCT values could reflect a change in the dynamics of the immune response secondary to the first infectious event.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 2","pages":"415-424"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Application of a short version of the Barthel Index for functional stratification in inpatients with multiple pathology (Mini-Barthel)]. [简易Barthel指数在多重病理住院患者功能分层中的应用（Mini-Barthel）]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

Dino Moretti, Guido Novello, Carina Cadavay, Matias Talamona, Karen Claverie, María Florencia Michel, María Paz Olivieri, Victoria Cagliero, Martín Migliaro, Juliana Castro, Francisco Rossi, Nadia Quiñones, Martín Buncuga

{"title":"[Application of a short version of the Barthel Index for functional stratification in inpatients with multiple pathology (Mini-Barthel)].","authors":"Dino Moretti, Guido Novello, Carina Cadavay, Matias Talamona, Karen Claverie, María Florencia Michel, María Paz Olivieri, Victoria Cagliero, Martín Migliaro, Juliana Castro, Francisco Rossi, Nadia Quiñones, Martín Buncuga","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Functional impairment is prevalent in patients with multiple pathologies (PP) and implies the need for caregivers, impaired quality of life, and increased mortality. The objective was to evaluate the functional stratification and prognostic performance of the MiniBarthel (MB), a short, simplified, three-dimensional version of the Barthel Index (BI), in hospitalized PP.Materials and methods: A prospective, observational study was conducted. The PROFUND prognostic score was administered upon admission, and patients were classified as MB0 (cannot do anything alone), MB1 (can feed themselves), MB2 (can feed and ambulate alone), and MB3 (can feed, ambulate, and climb stairs alone) by the attending physician. The BI was determined by the physical therapist to maintain the blinding. A 12-month follow-up was conducted to assess survival.Results: Ninety-nine patients were enrolled in the study, of whom 50 (50.5%) died during follow-up. They classified 21%, 17%, 17%, and 44% of patients as MB0, MB1, MB2, and MB3, with a median (IQR) BI of 10 (5- 20), 50 (40-60), 85 (75-90), and 95 (80-100) p < 0.001 and mortality of 66%, 64%, 52%, and 34% p 0.014, respectively. The area under the curve (AUC) (95% CI) of PROFUND, IB, and MB to discriminate 12-month mortality was 0.661 (0.553-0.769), 0.655 (0.547-0.762), and 0.654 (0.546-0.749), respectively.Conclusion: The Mini-Barthel's high performance, simplicity, and ease of use for functional stratification would enable a proactive approach to frailty and dependency care, focusing on functional decline and prognosis in hospitalized patients with multiple pathologies.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 2","pages":"425-438"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Analysis of a population of patients with hip fracture in Argentina]. [阿根廷髋部骨折患者人群分析]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2026-01-01

María Cecilia Tibaldo, Mariana González Pernas, Vanesa Longobardi, Sergio Giordano, Emanuel J Saad, María Belén Zanchetta

{"title":"[Analysis of a population of patients with hip fracture in Argentina].","authors":"María Cecilia Tibaldo, Mariana González Pernas, Vanesa Longobardi, Sergio Giordano, Emanuel J Saad, María Belén Zanchetta","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: In older adults, hip fracture (HF) is one of the main clinical consequences of osteoporosis. The objective of this study was to describe the clinical characteristics, biochemical parameters of bone metabolism, and densitometric findings in patients with fragilityrelated HF evaluated in a specialized center.Materials and methods: We conducted a retrospective descriptive study of patients over 18 years old diagnosed with fragility-related HF and evaluated at the Metabolic Research Institute in Buenos Aires between 2012 and 2022. Patients with fractures secondary to neoplasms, traffic accidents, or atypical femoral fractures were excluded.Results: Eighty patients were included, of whom 77 (96.3%) were women. The median age was 73 years (IQR 66-80). The most frequent fracture site was the femoral neck (74/80; 92.5%). Thirty-one patients (38.8%) had a history of previous fractures, and 20/31 (64.5%) had more than one. Bone densitometry was performed in 62/80 patients (77.5%) at trabecular sites, showing osteoporosis in 26/62 (41.9%) and osteopenia in 23/62 (37.1%), and in 54/80 (67.5%) at cortical sites, showing osteoporosis in 27/54 (50%) and osteopenia in 26/54 (48.1%). Forty-four patients (55%) had previously received osteoporosis treatment, and 17/80 (21.3%) were on active treatment at the time of the fracture. The median duration of prior bisphosphonate use was 44.7 months (IQR 13.5-60).Conclusion: Most patients with HF were older women. Among those who had undergone prior bone densitometry, half had osteoporosis, and approximately one-third were receiving active pharmacological treatment at the time of the fracture.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 2","pages":"360-369"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0