Medicina-buenos Aires最新文献_第3页

Assessment of Greek and Latin terminology by medical students. 医学生对希腊语和拉丁语术语的评估。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Manuel E Cortés, Eduardo Herrera-Aliaga, Luis Vicencio-Villaseca

引用次数: 0

[Intestinal pneumatosis and pneumoperitonum: not always a surgical indication]. [肠积气和腹腔积气：不一定是手术指征]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Julio César Rotondaro, Manuel Maya, Magalí Gutierrez, Gonzalo L Echavarria, Gustavo H Badariotti

{"title":"[Intestinal pneumatosis and pneumoperitonum: not always a surgical indication].","authors":"Julio César Rotondaro, Manuel Maya, Magalí Gutierrez, Gonzalo L Echavarria, Gustavo H Badariotti","doi":"","DOIUrl":"","url":null,"abstract":"Pneumatosis intestinalis and pneumoperitoneum are not pathological entities in themselves, they are radiological signs that result from some underlying condition. In general, these are associated with serious intra-abdominal processes that result in emergency surgeries with bowel resections. Below, we present the case of an 80-year-old woman, diagnosed with stage IV breast cancer under treatment with fulvestrant and ribociclib, who was admitted to our center due to abdominal pain and vomiting. She was diagnosed with intestinal pneumatosis and pneumoperitoneum, so she underwent exploratory laparotomy for suspected intestinal ischemia. There was no evidence of intestinal necrosis or perforation, so resection was not performed. She progressed satisfactorily during hospitalization and in the tomographic control one month after discharge there was complete resolution of the condition. Although this condition has been described in relation to episodes of increased intra-abdominal pressure, such as emesis, it has also been described in patients with neoplasms, mainly of the digestive tract, either due to local damage or toxicity associated with chemotherapy. We found no reports in the literature of pneumatosis intestinalis linked to this antineoplastic medication in humans. Probably in our case the etiology was multifactorial. It is possible that ribociclib played a role, either through an indirect mechanism associated with vomiting and immunosuppression or directly on the enterocyte due to its non-specific cellular mechanism of action.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Primary hepatic sarcomatoid carcinoma, an unusual case]. [原发性肝肉瘤样癌，一个不寻常的病例]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Darío A Rueda, Florencia Antinucci, Marcelo F Amante, Carlos A Bas

引用次数: 0

[Molecular diagnosis of bacteriaemia: benefits of using the FilmArray® BCID2 sepsis panel in a third level hospital]. [细菌血症的分子诊断：在一家三级医院使用 FilmArray® BCID2 败血症面板的益处]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Natalia A Díaz, Javier Farina, Liucó Zubeldía Brenner, Glenda Guzman, Sofía Lucini, Candela Serra, María Laura Negro, María Florencia Gil

{"title":"[Molecular diagnosis of bacteriaemia: benefits of using the FilmArray® BCID2 sepsis panel in a third level hospital].","authors":"Natalia A Díaz, Javier Farina, Liucó Zubeldía Brenner, Glenda Guzman, Sofía Lucini, Candela Serra, María Laura Negro, María Florencia Gil","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Delay in initiating appropriate antimicrobial therapy prolongs hospitalization, increases in-hospital mortality, and raises economic costs. Currently, the identification and susceptibility testing of bacteria in positive blood cultures require a considerable amount of time. The objective of this study was to assess the impact of the BCID2 FilmArray® (FA) panel on the timing of appropriate antimicrobial therapy and potential antimicrobial costs.Methods: This is a retrospective observational study focused on positive blood cultures in hospitalized patients. FA processing was conducted concurrently with routine sample processing. Changes in antibiotic treatments based on FA results were evaluated, and the reduction in antimicrobial therapy duration and associated cost savings were calculated.Results: Eighty-seven bacteremia episodes were analysed. In 42 (48%) of them antimicrobial therapy was de-escalated to narrower spectrum agents, while in 7 (8%) therapy was escalated to broader spectrum antimicrobials. Additionally, in 8 (9%) antimicrobials were switched without changing spectrum and in 30 (34%) no changes were made based on FA results. Antimicrobial changes were made 2.3 days faster than with routine sample processing resulting in calculated potential savings of US$ 7408.Conclusion: The implementation of FA facilitated a faster administration of appropriate antimicrobial therapy, leading to a reduction in the duration of broadspectrum empirical antimicrobial therapy and subsequent economic savings.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Abscessed tuberculomas in immunocompetent patient]. [免疫功能正常患者的脓毒性结核瘤]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

María Victoria Perez Allub, Cinthya Reznik, Ignacio Saguier Padilla, Alberto R Aguirre, Silvia S Folgar, Flavio C B Mercado

引用次数: 0

[Brush migration in a tracheostomized patient]. [气管插管病人的刷子移位]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Hugo Paez Pastor, Juan Rouquaud, Artemio Garcia, Julieta Franzoy, Pablo Young

引用次数: 0

[Cholestasis, delirium and pulmonary nocardiosis in a man with systemic lupus erythematosus of late onset]. [一名晚期系统性红斑狼疮患者的胆汁淤积症、谵妄和肺诺卡氏病]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Pablo Schuarzberg, Martín Gil Folgar, Benjamín F Barakian, Florencia Falcón, Claudia Barberis, Ricardo E Barcia

{"title":"[Cholestasis, delirium and pulmonary nocardiosis in a man with systemic lupus erythematosus of late onset].","authors":"Pablo Schuarzberg, Martín Gil Folgar, Benjamín F Barakian, Florencia Falcón, Claudia Barberis, Ricardo E Barcia","doi":"","DOIUrl":"","url":null,"abstract":"A case is presented of a 64-year-old male patient who was admitted because of delirium, jaundice, a pattern of cholestasis in the liver profile and a right lung mass in the context of a constitutional syndrome and weight loss in the last eight months. The lung mass was punctured and the culture of the obtained material developed white colonies, identified by mass spectrometry (MALDI-TOF) as Nocardia cyriacigeorgica. Regarding the clinical diagnosis, it was considered as systemic lupus erythematosus (SLE), on the basis of fulfilling 8 criteria according to SLICC 2012 group, and 24 points according to EULAR/ACR 2019. The liver biopsy showed a mixt cellular infiltrate in portal spaces, with absence of interphase hepatitis and presence of peripheral ductular reaction. These findings were interpreted as liver compromise relate to SLE. Delirium was also considered as a neurological manifestation related to SLE on the basis of ruling out other causes. After being treated with antibiotics and documenting a reduction in the size of the lung mass he received cyclophosphamide in intravenous pulses, achieving normalization of his liver profile and his state of consciousness, and a progressively weight recovering. A year after he was in good health. The report of this case is justified because of the rare presenting form of late onset SLE, as well as the concomitant pulmonary nocardiosis in the absence of previous immunosuppressant treatment.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Ewing sarcoma/primitive hepatic neuroectodermal tumor]. [尤文肉瘤/原始肝神经外胚层瘤]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Alfredo S Golemba, Astor A Aguirre Santamaría, Raúl E García Tolosa

{"title":"[Ewing sarcoma/primitive hepatic neuroectodermal tumor].","authors":"Alfredo S Golemba, Astor A Aguirre Santamaría, Raúl E García Tolosa","doi":"","DOIUrl":"","url":null,"abstract":"Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET) belong to the group of neoplasms called small round cell tumors. PNETs have been divided into central and peripheral. ES and peripheral PNETs arise from bones, soft tissues, or peripheral nerves. We present a case of hepatic ES/PNET in a healthy man that began four months before consultation with abdominal symptoms and weight loss. Upper gastrointestinal endoscopy and laboratory tests revealed no notable findings. The abdominal tomography revealed an enlarged liver due to a solid lesion that involved all its segments with intravenous contrast enhancement and large areas of necrosis. It compressed and displaced neighboring structures. Core needle biopsy of the liver lesion was performed: small round cell neoplasm. Immunohistochemistry revealed negativity for CD45, CKA1/A3, chromogranin, synaptophysin, and cytokeratins CK7 and CK20. Dim CD56 expression and CD99, FLI-1, and NKX2 positivity. He underwent chemotherapy treatment with carboplatin and etoposide for 6 cycles with clinical improvement and tolerance. Control images showed reduction of the mass with involvement of the right hepatic lobe, involvement of the inferior vena cava, infiltration of the right adrenal gland and upper pole of the right kidney. He was referred to hepatobiliary surgery for surgical resection of the residual lesion. The patient rejected the proposed surgical procedure. Our objective is to highlight the clinical and histological diagnostic challenge of this entity that requires ruling out other clinical entities.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pituitary metastases: a diagnostic and therapeutic challenge]. [垂体转移瘤：诊断和治疗的挑战]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Mónica G Loto, Amelia Rogozinski, Analia Alfieri, María C Ballarino, María F Battistone, Alberto Chervin, Karina D Danilowicz, Sabrina Diez, Patricia Fainstein Day, Alejandra Furioso, Mariela Glerean, Mariana Gonzalez Pernas, Débora Katz, María S Mallea Gil, Marcela Martinez, Karina A Miragaya, Maria I Sabate, Patricia Slavinsky, Soledad Sosa, Gabriela Szuman, Julieta Tkatch, Marcelo N Vitale, Mirtha Guitelman

{"title":"[Pituitary metastases: a diagnostic and therapeutic challenge].","authors":"Mónica G Loto, Amelia Rogozinski, Analia Alfieri, María C Ballarino, María F Battistone, Alberto Chervin, Karina D Danilowicz, Sabrina Diez, Patricia Fainstein Day, Alejandra Furioso, Mariela Glerean, Mariana Gonzalez Pernas, Débora Katz, María S Mallea Gil, Marcela Martinez, Karina A Miragaya, Maria I Sabate, Patricia Slavinsky, Soledad Sosa, Gabriela Szuman, Julieta Tkatch, Marcelo N Vitale, Mirtha Guitelman","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Sellar metastases (SM) are rare manifestations of malignancy. Breast and lung cancer are the most common primary tumors. Most cases are diagnosed in patients with advanced malignant disease; however, symptoms of pituitary involvement can precede the diagnosis of the primary tumor.Methods: Retrospective analysis of symptoms at presentation, hormonal, radiological and histological findings, management, and outcome of patients with SM from 2009 to 2020.Results: Eighteen patients'cases were included, 11 with histological confirmation. Median (m) age was 53 years (range 35-75), 53% male. Primary malignant tumors: 8 lungs, 6 breast, 1 follicular thyroid carcinoma, 1 Hodgkin lymphoma, and 2 clear cell renal carcinomas. The m time between the diagnosis of the primary neoplasm and the occurrence of the SM was 108 months (range: 11-180). In 8 patients the diagnosis of the primary neoplasm was made after the finding of the symptomatic sellar mass. Insipidus diabetes, adenohypophysis deficit, visual disorders, headache, and cranial nerve deficits were evident in 78, 77, 61, 39 and 39% of the cases, respectively. Fifteen patients harbored supra / parasellar masses, in three a lesion was limited to the pituitary gland, and stalk. Eleven out of 18 (61.1%) of the patients were operated on by the trans-sphenoidal approach, for diagnostic and / or decompressive purposes. Eighteen died, with a median survival time of 6 months (1-36).Discussion: In the presence of a pituitary lesion with diffuse gadolinium uptake, associated with insipidus diabetes and / or visual disorder SM should be suspected even in patients without a history of oncological disease.","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The dramatic funding cuts for scientific research will generate an unprecedent impoverishment of the Argentine future]. [科研经费的大幅削减将给阿根廷的未来带来前所未有的贫困]。

IF 0.8 4区医学

Medicina-buenos Aires Pub Date : 2024-01-01

Martín Sívori

引用次数: 0