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[Computerized cognitive training as a treatment for ADHD: evidence summary and future directions]. [计算机化认知训练作为ADHD的治疗方法：证据总结和未来方向]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-03-01

Jacobo Albert, Sara López-Martín, Alberto J Sánchez-Carmona, Beatriz Calleja-Pérez, Ana L Fernández-Perrone, Nuria Muñoz-Jareño, Ana Jiménez de Domingo, Daniel Martín Fernández-Mayoralas, Alberto Fernández-Jaén

{"title":"[Computerized cognitive training as a treatment for ADHD: evidence summary and future directions].","authors":"Jacobo Albert, Sara López-Martín, Alberto J Sánchez-Carmona, Beatriz Calleja-Pérez, Ana L Fernández-Perrone, Nuria Muñoz-Jareño, Ana Jiménez de Domingo, Daniel Martín Fernández-Mayoralas, Alberto Fernández-Jaén","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention and/or hyperactivity/impulsivity, which is associated with various neuropsychological deficits. These deficits are thought to mediate the relationship between etiological factors and the manifestation of the disorder, making them important targets for treatment. Within this context, and based on promising results, computerized cognitive training (CCT) through adaptive programs and/or video games has garnered considerable interest. Therapeutic programs and video games for ADHD have even been commercialized. However, the most rigorous and reliable evidence currently available suggests that CCT, in its current forms, lacks sufficient empirical support to be considered either a standalone or an alternative treatment to first-choice interventions for ADHD. Its effects on core ADHD symptoms are modest and limited, with minimal transfer or generalization to other contexts or functional skills. The complexity of ADHD suggests that highly specific, singular interventions such as CCT may be neither appropriate nor sufficient as standalone treatments. Further research is needed to evaluate the added effects of CCT when integrated with existing treatments, including its role within more holistic and comprehensive neuropsychological interventions.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 Suppl 1 ","pages":"30-35"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Scimitar syndrome]. (弯刀综合症)。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Jacqueline M Galiano, Kevin Santana Alessio, Carlos A Soler

引用次数: 0

"I would prefer not to". Autonomy and the boundaries of medical intervention. “我不愿意。”自主性和医疗干预的界限。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Gustavo Kusminsky

引用次数: 0

[Ectopic ACTH secretion by neuroendocrine carcinoma of the uterine cervix]. [宫颈神经内分泌癌异位分泌促肾上腺皮质激素]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Eugenia C Authier Cipolla, Mara R Touriñan, Carolina B Lamonica, Agostina R Bazzi, Noelia Y Scagliarino, Silvina Tormo, Julieta Guyot, Paola C Vigna, Evangelina Giacoia

{"title":"[Ectopic ACTH secretion by neuroendocrine carcinoma of the uterine cervix].","authors":"Eugenia C Authier Cipolla, Mara R Touriñan, Carolina B Lamonica, Agostina R Bazzi, Noelia Y Scagliarino, Silvina Tormo, Julieta Guyot, Paola C Vigna, Evangelina Giacoia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cushing's syndrome due to ectopic ACTH secretion (EAS) is a consequence of deregulated ACTH secretion by neuroendocrine neoplasms with different locations, most commonly in the thorax. Neuroendocrine tumors represent less than 2% of all invasive cervical cancers. They tend to be highly aggressive, showing rapid growth and distant metastasis at the time of diagnosis. We present a 25-year-old female, with no relevant medical history, who came to our hospital with 1-monthold acne-like lesions on the face, neck, and chest, facial edema, blurred vision, and progressed with delirium, incoherent speech, and suicidal ideation. Hypertension, hypokalemia, hyperglycemia, and metabolic alkalosis were found. The condition was interpreted as a severe, rapid-onset Cushing's syndrome, with significant compromise in general condition. The syndrome and its dependence on ACTH were confirmed by biochemical tests. Computed tomography revealed multiple lesions in the liver and spine suggesting metastatic cancer. After reporting a history of postcoital bleeding, a speculoscopy was performed, and a biopsy was taken of the cervix, as well as the liver lesions. In both cases, histopathological findings revealed the presence of small cell neuroendocrine carcinoma, and chemotherapy with cisplatin and etoposide was initiated. This case represents an example of an uncommon disease that usually implies an important diagnostic and therapeutic challenge. The severity of this condition may be a consequence of the aggressiveness of the ACTH-secreting tumor and/or hypercortisolism with its multiple complications.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 2","pages":"439-444"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[In-hospital mortality from cerebrovascular accidents in an urban center in Argentina]. [阿根廷城市中心的脑血管意外住院死亡率]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

María Martina Echarri, Federico Rodríguez Lucci, Virginia Pujol Lereis, Marina Y Finkelsztein, Claudio D González, Sebastián F Ameriso

{"title":"[In-hospital mortality from cerebrovascular accidents in an urban center in Argentina].","authors":"María Martina Echarri, Federico Rodríguez Lucci, Virginia Pujol Lereis, Marina Y Finkelsztein, Claudio D González, Sebastián F Ameriso","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>In-hospital mortality is influenced by various factors. Despite the trend toward decreased mortality from acute stroke in the Northern Hemisphere, reports in our region show variable figures. This study reports in-hospital mortality for the second time from a medical center in Ciudad de Buenos Aires. Factors associated with mortality in these patients were also identified.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted using data from the FLENI Stroke Database between 2010 and 2019, analyzing clinical characteristics, risk factors, complications, and mortality of hospitalized patients. Univariable and multivariable statistical analyses were used to identify risk factors associated with in-hospital mortality.</p><p><strong>Results: </strong>Data from 1645 patients were analysed, of which 1476 (90%) had ischemic stroke, 95 (6%) had hemorrhagic stroke, and 74 (4%) had aneurysmal subarachnoid hemorrhage (aSAH). There were 45 in-hospital deaths (2%): 26 deaths (1%) from ischemic stroke, 11 deaths (11%) from hemorrhagic stroke, and 8 deaths (10%) from aSAH. Factors associated with mortality include advanced age, low hemoglobin levels at admission, higher scores on the NIHSS scale at admission, and a history of diabetes mellitus.</p><p><strong>Discussion: </strong>In-hospital mortality from stroke remains low in our institution, with differences between ischemic and hemorrhagic stroke. Factors such as stroke severity, hemoglobin levels, and a history of diabetes mellitus are independent predictors of mortality.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 2","pages":"337-347"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The most frequent tumor, an unusual site and risk of cancer]. [最常见的肿瘤，一个不寻常的位置和癌症的风险]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Emmanuel A Zappettini, Santiago Castilla, Guido M Pianzola, Bárbara Marín, Gustavo A Marinucci, Pablo D Marinucci

引用次数: 0

[Ischemic mitral regurgitation: from the emergency room to the cardiac surgery recovery unit]. [缺血性二尖瓣反流：从急诊室到心脏外科康复病房]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Juan M Iroulart, Juan I Lagoria, Ignacio M Bluro, Ana L Miceli, Mariano G Bergier, Ricardo Posatini, Rodolfo Pizarro

引用次数: 0

[Dismantling the National Cancer Institute: An unacceptable setback for Public Health]. [解散国家癌症研究所：公共卫生不可接受的挫折]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Graciela Jacob

引用次数: 0

[Plasma cortisol by trimester of pregnancy: study from an Argentine hospital]. [妊娠三个月血浆皮质醇：阿根廷一家医院的研究]。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Franco N López López, Silvina Tormo, Mauro G Cruseño, Eduardo Moratto, Evangelina Giacoia

{"title":"[Plasma cortisol by trimester of pregnancy: study from an Argentine hospital].","authors":"Franco N López López, Silvina Tormo, Mauro G Cruseño, Eduardo Moratto, Evangelina Giacoia","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Maternal cortisol undergoes variations in its levels secondary to physiological adaptations. Maternal cortisol secretion increases from the 25th week of pregnancy, estimated to reach twice the value of nonpregnant women in the third trimester. The objectives of this study were to demonstrate the increase in cortisol values in pregnancy and establish reference ranges of plasma cortisol trimester specific to our population of healthy pregnant women.</p><p><strong>Materials and methods: </strong>Cortisol measurement was performed in 186 healthy pregnant women between 2020 and 2023, 62 women were analyzed for each trimester of pregnancy, including age, body mass index (BMI), previous pregnancies, glycemia and ionogram.</p><p><strong>Results: </strong>The median age was 27 (18 - 47) years, previous pregnancies 1 (0-9), BMI 25.7 (16.6 - 46.2) kg/m2. In the first trimester, the median cortisol level was 14.1 (7.53 - 31.0) ug/dL; in the second trimester 20.5, (10.0 - 47.2) ug/dl and in the third trimester 23.2, (11.8 - 33.1) ug/dL. The increase in cortisol throughout the trimesters was statistically significant p < 0.001.</p><p><strong>Discussion: </strong>In this study, cortisol values were identified by specific trimester, which could show an increase throughout pregnancy. Having reference values allows for proper interpretation and clinical diagnosis of endocrine diseases at this stage of life.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"85 3","pages":"495-500"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sodium and menopause. Dopamine D1-receptors, Na+-K+-ATPase and CD4+ in peripheral blood as markers of renal inflammation. 钠和更年期。外周血多巴胺d1受体、Na+-K+- atp酶和CD4+作为肾脏炎症的标志物。

IF 0.6 4区医学

Medicina-buenos Aires Pub Date : 2025-01-01

Sandra G Vlachovsky, Fernando R Ibarra, Luis Di Ciano

引用次数: 0

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