{"title":"[Autism: Insistence on invariance. Understanding and treatment].","authors":"Juan Martos Pérez, María Del Sol Fortea Sevilla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The issue of insistence on invariance, resistance to change, in the field of autism is addressed. We explain the intense and direct relationship between the development of self-regulation skills, along with social development and communication skills, which does not occur as expected in autism, and the emergence of a functioning pattern in autistic individuals characterized by insistence on invariance. We also explain how to address resistance to change in the physical and social worlds, as well as in the processing of sensory information, when treating autism.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"14-19"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Impact of devices and social media on the neurodevelopment and mental health of children and adolescents].","authors":"Germán Casas, Manuela Becerra Duarte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Early exposure to digital devices and social media has been suggested as a relevant environmental factor that may influence neurocognitive maturation during childhood and adolescence. The limited scientific evidence available indicates that excessive and unregulated use could negatively affect multiple developmental domains, including language acquisition, executive functioning, attentional control, emotional regulation, and psychosocial outcomes. Although the current evidence does not allow for definitive claims of causality, the observed associations appear suggestive of potential links with these symptoms. In young children, prolonged screen time might be associated with language delays, impairments in working memory, and sleep disturbances. Among adolescents, compulsive use of social media may hyperactivate mesolimbic dopaminergic pathways, potentially reinforcing maladaptive reward-seeking behaviors and increasing vulnerability to anxiety, depression, and low self-esteem. These findings highlight the urgent need for evidence-based preventive strategies, parental mediation, and comprehensive public health interventions. While absolute certainty of causality is lacking, further investigation into these possible risks remains necessary.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"79-85"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Towards transformational high intellectual ability: ethical regulation].","authors":"Sylvia Sastre-Riba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concept of high intellectual ability (HIA) is being redefined to incorporate its transformational dimension. The high intellectual potential that characterizes it should not only be directed towards personal achievement, but also providing a transformational response involving positive social responsibility and the ethical regulation of high potential. Research suggests that schoolchildren and adolescents with HIA demonstrate higher and earlier ethical sensitivity than their peers, but academic excellence does not necessarily lead to social responsibility. Therefore, it is necessary to educate their executive and ethical regulation and other functional traits, such as critical thinking and wisdom. This work aims to understand how ethical sensitivity contributes to the transformational expression of HIA. A comparative theoretical review of scientific articles on the subject was carried out, combined with empirical results from previous research on the subject. Two fundamental ideas are incorporated into the concept of HIA: its development and the importance that this development is not only directed towards individual achievements but is also transformational, that is, giving rise to socially beneficial behaviors. The discussion focus on the need for educating the executive and ethical regulation of high intellectual potential in a transformational HIA in order to offer effective solutions to the complexities of the 21st century.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"65-71"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melva Gissele Flores, María Eugenia Russi, Xenia Alonso, Oscar Sans Capdevila
{"title":"[Insomnia in children with autism spectrum disorder].","authors":"Melva Gissele Flores, María Eugenia Russi, Xenia Alonso, Oscar Sans Capdevila","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In children and adolescents with autism spectrum disorder (ASD), an association has been identified between sleep problems, cognitive function, and affective dysregulation. This association exacerbates the core manifestations of autism and increases the risk of developing behavioral problems, irritability, hyperactivity, and inattention. The link between sleep problems and the central symptoms of ASD, along with their multiple associations with other health issues, demonstrates that addressing sleep problems from childhood improves physical and mental health, as well as cognitive and adaptive functioning. Medical treatment should follow a stepped algorithm, starting with pediatric longrelease melatonin (PRLM), followed by alimemazine, risperidone, and clonidine, depending on the patient's clinical response.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"32-42"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elisa Piedra-Martínez, Manuel R Morte-Soriano, Manuel Soriano-Ferrer
{"title":"[Internalizing disorders in students with dyslexia].","authors":"Elisa Piedra-Martínez, Manuel R Morte-Soriano, Manuel Soriano-Ferrer","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Students diagnosed with dyslexia show a higher risk of internalizing problems (anxiety, depression, and low self-concept). Therefore, the main objective of this study was to examine internalizing problems in students with dyslexia.</p><p><strong>Materials and method: </strong>Thirty-seven students with dyslexia (DG) and a comparison group of thirty-nine typically developing students (GC) participated. Selfreport measures of anxiety, depression, academic selfconcept, and reading self-concept were administered.</p><p><strong>Results: </strong>Self-reports of internalizing disorders indicated that students in the dyslexia group (DG) exhibited higher levels of depressive symptoms, greater anxiety state, lower academic self-concept, and lower reading self-concept compared to students in the control group (CG).</p><p><strong>Discussion: </strong>In conclusion, our findings suggest that the internalizing disorders experienced by students with dyslexia should be recognized early and promptly addressed by education professionals.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"72-78"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naiara Minto De Sousa, Reyes Martínez Borondo, Luís Abad Mas
{"title":"[Social skills in adults with late-onset diagnosis of ASD and ADHD].","authors":"Naiara Minto De Sousa, Reyes Martínez Borondo, Luís Abad Mas","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Social skills (SS) in individuals with Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are typically affected.</p><p><strong>Objectives: </strong>To compare whether there are significant differences in the SS of adults diagnosed with ASD and ADHD.</p><p><strong>Patients and methods: </strong>77 adults (18 to 59 years-old), assessed at a private health center in the Valencian Community in 2024. The group diagnosed with ADHD included 38 participants, 22 were women (mean age 32 ± 12.3 years). The ASD group included 39 adults, 25 were women (mean age 33 ±10.6 years). All participants had a Total IQ >80 and had received prior psychological treatment for less than two years. SS were measured with a Social Skills Scale (EHS) developed. Using a nonparametric design (Mann-Whitney), we compared the medians of the two independent groups across the six SS dimensions and the SS global score. Differences by gender were also investigated.</p><p><strong>Results: </strong>Significant differences were observed in all SS scores between the groups, except for EHS III and VI. The p-values were 0.00* for the EHS I; 0.04* for the EHS IV and EHSV; and 0.01* for the global score. No significant differences were found according to gender.</p><p><strong>Discussion: </strong>The EHS scale may support the differential diagnosis between ASD and ADHD in adults. The average-to-superior intelligence profile of these adults is remarkable, including profiles of High Intellectual Abilities concomitant with ASD/ADHD. Future studies could expand the sample and check the relation of SS scores and anxious and depressive symptomatology or autistic traits and camouflaging scores.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"43-48"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hali Temkin, Kerri L Daniel, Diana Martinez, Julia C Bennett, Paris A Nix, Linh Nguyen, Yen-Chi Le, Bruno Kluwe-Schiavon, Cesar A Soutullo
{"title":"[Factors associated with ADHD medication adherence and treatment outcomes].","authors":"Hali Temkin, Kerri L Daniel, Diana Martinez, Julia C Bennett, Paris A Nix, Linh Nguyen, Yen-Chi Le, Bruno Kluwe-Schiavon, Cesar A Soutullo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that affects 5 to 8% of youth and 2.5 to 4% of adults. Pharmacological treatments are among the most effective when treating ADHD, yet adherence to medication is still sub-optimal. We reviewed the literature on clinical and socio demographic factors that may influence adherence and compared it to our clinical data.</p><p><strong>Methods: </strong>We conducted a targeted literature review on factors associated with ADHD medication adherence. These factors were compared within our sample of patients aged 3-18 with ADHD at the Child and Adolescent Mood Disorders Program (ChAMP) at (UT Health) - Houston. We assessed relations between measurement-based care (MBC) and socio demographic factors.</p><p><strong>Results: </strong>We found factors associated with adherence rates included patient age, level of parental involvement, psychiatric comorbidities, familial psychiatric history, and socioeconomic status. ADHD medication adherence improved and symptom severity decreased over 24 months. Each additional year in age, multiple siblings, and =1 parent receiving psychiatric treatment were associated with greater symptom severity.</p><p><strong>Discussion: </strong>Results suggest that MBC is a useful method for reducing overall ADHD severity and improving medication adherence in children and adolescents. Additionally, MBC programs should consider screening for and addressing family psychiatric history and household structure as these relevant factors affect ADHD medication adherence.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"49-57"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Autism - the problem of double empathy].","authors":"Víctor Ruggieri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autism is a neurodevelopmental disorder defined by a qualitative impairment in social interaction and communication, along with restricted interests and stereotyped behaviors. Various neurobiological, genetic, and epigenetic bases are recognized. Thirty percent of autistic individuals are severely or nonverbally autistic. The failure of autistic individuals to socialize is related to their impairment in social cognition, linked to deficits in empathy and theory of mind. Recently, this \"inability to relate to peers\" has been framed as a two-way problem between the autistic person and the \"typical\" person, hence the concept of the \"double empathy problem\". This implies that not only is the autistic person dysfunctional in social interaction, but so is the nonautistic interlocutor. The problem of dual empathy allows for a new understanding of autism and, to some extent, puts into perspective the challenges faced by autistic and nonautistic individuals as part of a shared deficit, not solely attributable to the autistic person. While it facilitates awareness of neurodiversity and challenges us all in relation to autism, solid explanations are still lacking to accept this concept as valid in the genesis of the social problems faced by autistic individuals and its application in clinical practice and education. This article analyzes aspects of empathy and the problem of double empathy, highlighting their characteristics and limitations for the interpretation of autism.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"20-25"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Eleonora Minissi, Alberto Altozano, Lucia Gómez-Zaragozá, Luna Maddalon, Mariano Alcañiz, Javier Marín-Morales
{"title":"[Autism detection based on computational analysis of parental language].","authors":"Maria Eleonora Minissi, Alberto Altozano, Lucia Gómez-Zaragozá, Luna Maddalon, Mariano Alcañiz, Javier Marín-Morales","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Early detection of autism spectrum disorder (ASD) requires integrating clinical observation with developmental history and everyday functioning, yet care pathways are often strained by high demand and limited specialist resources. In this context, parents' narratives provide ecologically valid signals about social communication, language, and repetitive behaviors; however, free-form accounts are difficult to analyze systematically in routine practice. This article reviews a special study, which automatically analyzed caregivers' openended responses to 12 questions inspired by the ADI-R in 51 families (children aged 2-8 years; 25 ASD and 26 controls). The study aimed to automatically detect ASD in children through computational analysis of parents' speech. The best subject-level classification strategy was achieved by converting text into semantic representations (using OpenAI's text-ada-embedding-large-v3), training models per question, including the question in the input, and aggregating decisions via majority voting (84% accuracy; ROC-AUC 1.0). The clinical goal of this pilot study was to demonstrate the potential to support screening, prioritization, and referral, and potentially reduce waiting times and professional burden, thereby improving timely access to evaluation and early intervention. We discuss limitations (small sample, selected population, possible influence of prior intervention) and ethical risks (sociolinguistic bias, privacy, stigmatization, false positives/negatives), and we propose steps toward responsible clinical translation.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"26-31"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucía Domingo Moscardó, Inmaculada Baixauli Fortea, Carmen Berenguer Forner
{"title":"[\"Good night, gorilla\": Evaluating narratives in children with autism spectrum disorder].","authors":"Lucía Domingo Moscardó, Inmaculada Baixauli Fortea, Carmen Berenguer Forner","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study is to propose and apply a systematic narrative analysis protocol for one of the tasks included in the Autism Diagnostic Observation Schedule (ADOS-2), in order to compare narrative production in Autism Spectrum Disorder (ASD) and typical development, as well as to examine the relationship between narrative ability and ASD severity.</p><p><strong>Materials and methods: </strong>Twenty-four children (12 with ASD without intellectual disability; 12 with typical development) were assessed using the story \"Goodnight, Gorilla\". The narratives were analyzed in terms of length, syntactic complexity, content and internal state language.</p><p><strong>Results: </strong>The ASD group produced significantly shorter narratives with fewer main ideas. No significant differences were found in syntactic complexity and internal state language. No correlations were found between ASD severity and narrative indicators.</p><p><strong>Conclusion: </strong>Although children with ASD produced narratives with similar syntactic complexity, they showed difficulties in selecting and integrating essential information, indicating a dissociation among the linguistic abilities involved in narrative discourse. The applied protocol may serve as a useful resource for ASD assessment and for planning interventions aimed at fostering narrative skills in this population.</p>","PeriodicalId":18419,"journal":{"name":"Medicina-buenos Aires","volume":"86 Suppl 1 ","pages":"58-64"},"PeriodicalIF":0.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}