Micro & Nano Letters最新文献

{"title":"Preconcentration and measurement of trace Amitriptyline hydrochloride in water samples using magnetic nanoparticles with dispersive solid-phase extraction","authors":"Arghavan Amin,&nbsp;Ali Moghimi","doi":"10.1049/mna2.12184","DOIUrl":"https://doi.org/10.1049/mna2.12184","url":null,"abstract":"<p>In the separation and determination of trace amounts of drugs in aqueous samples, there is a major challenge in synthesizing highly efficient, cost-effective, and easy-to-use adsorbents based on natural polymers, which are also biocompatible and biodegradable. In the proposed method, magnetite nanoparticles (Fe₃O₄) on chitosan (as the carrier) modified with β-cyclodextrin (BCD) were used as a suitable adsorbent for the pre-concentration and solid-phase extraction of trace amounts of Amitriptyline HCl (hydrochloride). Ultraviolet spectrophotometer (λ = 236 nm) was the main instrument used for analyte detection and quantification. Moreover, X-ray diffraction, Fourier transform infrared spectroscopy, Field Emission Scanning Electron Microscopy, and Energy-Dispersive X-ray were used for the identification and characterization of the structure and morphology of the adsorbent and to establish the formation of the synthesized magnetic nanosorbents, as well as to confirm the analyte binding to the adsorbent. Experimental variables affecting the extraction/pre-concentration and determination of the analyte were investigated and optimized; pH of the sample solution, the amount of NaCl salt (in terms of ionic strength of the solution), the amount of adsorbent, temperature, adsorption time, and volume of the eluent (methanol) were the optimized parameters. Finally, the method was successfully applied for the determination of spiked Amitriptyline hydrochloride (HCl) in tap water and human urine samples. Also, High-Performance Liquid Chromatography was performed on the aqueous samples to compare the proposed method with the USP (the United States Pharmacopeia) standard method of Amitriptyline HCl assay and after performing a <i>t</i>-test (confidence level of 95%), no significant difference was observed between the two methods. High accuracy and precision (RSD = 3.91%), High analysis speed, few limitations, low expenses, pure extracted analyte, and low waste were the advantages of this method. This method was also compatible with many existing device methods. Under the optimized experimental conditions, the calibration graph was linear in the range of 0.183 to 50 mg.L⁻¹ with a correlation coefficient of 0.996. RSD of the method was 3.91%, the limit of detection was 37.8 µg.L⁻¹, the maximum sorption capacity of the adsorbent for Amitriptyline hydrochloride was 306.525 mg.g⁻¹ and the preconcentration factor was 3.61. Eventually, the proposed method was compared to other methods that have been performed for the determination of Amitriptyline hydrochloride.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"19 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139042302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biopolymer-based nanoparticles as promising candidate for inducing apoptosis in liver cancer cells","authors":"Mahsa Hoseinzadeh,&nbsp;Mohammad Javad Mokhtari,&nbsp;Farshid Kafilzadeh,&nbsp;Javad Mohammadnejad,&nbsp;Yaghoob Taheri","doi":"10.1049/mna2.12183","DOIUrl":"10.1049/mna2.12183","url":null,"abstract":"<p>Liver cancer is one of the most common causes of death all around the globe. On the other hand, conventional modalities, such as chemotherapy and surgery, have not been effectively suppressed cancer incidence due to some deficiencies. As a result, a novel folic acid (FA)-decorated poly lactic-co-glycolic acid (PLGA)-Alginate (Alg) nanocarrier was efficiently developed for active doxorubicin (Dox) delivery to human HepG2 liver cancer cells. The in vitro assays, including cell viability assay (MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test), apoptosis, cell cycle arrest, and cellular uptake, were applied to evaluate the cancer cell growth suppression and apoptosis-inducing ability of the nanocarrier. More than 85% cytotoxicity was attained after 24 h of treatment with 400-nM concentration of FA-PLGA-Dox-Alg. More than 21% and 61% apoptosis were observed after 24 h of treatment with 100-nM concentrations of FA-PLGA-Dox-Alg in apoptosis and cell cycle arrest assays. The cellular uptake of the FA-PLGA-Alg nanocarrier was about 30% higher than that of the PLGA-Alg carrier which indicated the cancer cell targeting ability of the FA-PLGA-Alg sample. These results have indicated the potential capability of FA-PLGA-Dox-Alg in the inhibition of liver cancer cells.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"19 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138822562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squeeze-film damping model of perforated plate considering border effect","authors":"Cunhao Lu,&nbsp;Zeyuan Zhang,&nbsp;Wei Liu,&nbsp;Jian Chen","doi":"10.1049/mna2.12185","DOIUrl":"10.1049/mna2.12185","url":null,"abstract":"<p>The squeeze-film damping (SQFD) is an important dissipation mechanism of Micro-Electro-Mechanical Systems resonators. The current SQFD models of perforated plates treat borders of plate and holes as the constant pressure boundary, without considering border effect. In this paper, the border effect on SQFD is studied by expanding simulation area. At the same time, based on the research of non-perforated plate border effect, the calculation size of the perforated plate hole cell is modified, and the modified SQFD model of the perforated plate has been built. Compared with simulation results, it shows the border effect has a great influence on SQFD of perforated plate. The precision of the modified model is higher than that of recent models. For a rectangular plate, the maximum error of the modified model is 12%, while for the recent model it is 40%. For a circular plate, the modified model is 38%, while the recent model is 58%.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"19 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138822620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization and application of lamellar zeolite-X prepared from kaolin","authors":"Weilin Jia,&nbsp;Suyang Wang,&nbsp;Yingying Deng,&nbsp;Jie Shen,&nbsp;Ping Zhao,&nbsp;Zepeng Wang,&nbsp;Jiaojing Shao,&nbsp;Yuanyu Wang,&nbsp;Qi Sun","doi":"10.1049/mna2.12182","DOIUrl":"10.1049/mna2.12182","url":null,"abstract":"<p>A simple and effective method was reported for the rapid synthesis of zeolite X from kaolin by adding a template agent. The results of X-ray diffraction confirm the good crystallinity of the synthesized X-zeolite with lamellar structure. Transmission electron microscopy images clearly demonstrate the lamellar structure of the synthesized X-zeolite. The corresponding selective electron diffraction pattern suggests that the crystal structure of X-type zeolite is octahedral. The co-existence and uniform distribution of Si, Al, O, and Na in the layered structure of the synthesized X-type zeolite are detected by element mapping. In addition, N₂ adsorption–desorption measurement indicates that the specific surface area of the lamellar zeolite X is 153.4625 m² g⁻¹. The micropore surface area is 148.8374 m² g⁻¹, and the micropore volume is 0.073377 m² g⁻¹. After exploring the influence of different temperatures on the adsorption of carbon dioxide, the research shows that two-dimensional zeolite X has the best adsorption capacity for carbon dioxide. The adsorption and separation performance of CO₂/CH₄ was investigated. The study showed that the adsorption and separation coefficient of two-dimensional zeolite X was the highest.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"19 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138822563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The preparation of PVA/PBS/LiCl hydrogels and their performance as conductive gels","authors":"Zheng Guo,&nbsp;Zebo Wang,&nbsp;Wei Pan","doi":"10.1049/mna2.12181","DOIUrl":"https://doi.org/10.1049/mna2.12181","url":null,"abstract":"<p>The article describes the preparation of polyvinyl alcohol (PVA)/polybutylene succinate (PBS)/lithium chloride (LiCl) hydrogels, their structural features, as well as their electrical and mechanical properties. Firstly, by using a twin screw extruder, the PBS was blended with plasticized PVA and then PBS fibres were formed during the process. Secondly, the PVA/PBS composite materials were dissolved in the binary mixed solvent of glycerol and water containing LiCl to prepare PVA/PBS/LiCl hydrogels by the sol-gel method. The morphology, structure, mechanical property, and conductivity of the hydrogels were investigated. The mechanical property of the hydrogels is improved with PBS fibres significantly and LiCl can improve the electrical conductivity of the hydrogels. The strength and conductivity of the PVA/PBS/LiCl (3 wt%) hydrogels are 4.67 MPa and 8.3 s/m, respectively. The PVA/PBS/LiCl hydrogels show good mechanical strength and conductivity and can be used in the wearable sensor field.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138439805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical gain of CdxZn1−xTe quantum dot structures","authors":"Muwaffaq Abdullah,&nbsp;Baqer O. Al-Nashy,&nbsp;Amin H. Al-Khursan","doi":"10.1049/mna2.12180","DOIUrl":"https://doi.org/10.1049/mna2.12180","url":null,"abstract":"Gain spectra of undoped and doped quantum dot (QD) structures are studied under the inhomogeneous broadening assumption at four mole fractions . For the QD structure, two peaks appear due to the excited state (ES) and ground state (GS) transitions. The gain for the doped structures doubles the undoped ones. The gain increases while the wavelength is reduced with increasing Cd content due to the broader band discontinuity between the QD states. The discontinuity of the bands for each structure (mole fraction) is calculated, which is one of the merits of this work. While the structure offers the peak wavelengths 470 and 630 nm, other mole fractions offer the wavelengths between them. These visible bands are essential in different applications. The effect of QD size effect is also examined. The wavelength is extended by 20 nm for each 1 nm QD height increment.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138439785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-fabrication of silver nanoparticles using an aqueous extract of Quercus baloot: Preparation, characterization and in vitro antimicrobial evaluation","authors":"Fazle Rabbi,&nbsp;Amna Nisar,&nbsp;Noor Ul Ain Nawaz,&nbsp;Najla AlMasoud,&nbsp;Taghrid S. Alomar,&nbsp;Abdur Rauf","doi":"10.1049/mna2.12179","DOIUrl":"10.1049/mna2.12179","url":null,"abstract":"<p>\u0000In the current study, a novel method was used to synthesize silver nanoparticles (AgNPs) by utilizing Quercus baloot aqueous extract as a reducing agent. The biosynthesized AgNPs were then subjected to various physicochemical characterizations to assess their effectiveness against microbial familiarity. The characterization techniques included ultraviolet-visible spectro-photometry (UV-Vis), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffractometer (XRD), and Fourier-transform infrared spectroscopy (FTIR). The UV-Vis analysis revealed a distinctive spectral peak at 420 nm, indicating the presence of silver nanoparticles. SEM imaging displayed the nanoparticle size range of about 100 nm at a magnification of 30,000x, while TEM demonstrated that the nanoparticles had a spherical morphology with a size of approximately 100 nm. Moreover, the crystalline structure of the silver nanoparticles was confirmed by XRD analysis, further validating their successful synthesis. Additionally, FTIR analysis provided evidence of the presence of phytochemicals involved in synthesizing the AgNPs. the biosynthesized silver nanoparticles (AgNPs) were evaluated for antibacterial and antifungal activities. The AgNPs displayed substantial efficacy against common bacterial strains, including Staphylococcus aureus (71%), Escherichia coli (59%), and Klebsiella pneumoniae (64%). Furthermore, they demonstrated significant antifungal activity against plant pathogenic fungi, namely Aspergillus niger (65%), Aspergillus flavus (70%) and Fusarium oxysporum (61%).</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135738478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controllability study of copper-tin-sulphide (Cu3SnS4) material based on the ratio adjustment of Cu to Sn elements","authors":"Mingrong Dong,&nbsp;Leikai Wei,&nbsp;Yan Zhu","doi":"10.1049/mna2.12176","DOIUrl":"10.1049/mna2.12176","url":null,"abstract":"<p>The synthesis of pure phase Cu₃SnS₄ is of great significance for improving its material properties. Here, the control law of Cu and Sn element ratio on the synthesis of pure phase Cu₃SnS₄ from physical and chemical methods was analyzed through literature research. The results: (1) the adjustment of the Cu-to-Sn ratio metal elements as a phase control parameter has the characteristics of flexibility and controllability. (2) When the precursor component is rich in Cu and the chemical potential of the medium and high sulphur is high, the phase will develop to a wider thermodynamically stable region of Cu₃SnS₄. By adjusting the Cu-to-Sn ratio elements, when the release rate of anions and the reaction rate of cations adapt to each other, the thermodynamic reaction conditions can be well satisfied, which is beneficial to the preparation of pure phase Cu₃SnS₄. (3) The phase control method of Cu and Sn element ratio of template seed crystal can not only realize the reasonable regulation of Cu and Sn element ratio but also control the synthesis of phase more accurately. The results of this paper have certain reference values for the application of new materials synthesized by adjusting the proportion of elements.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135737602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of cell damage of periodontopathic bacteria exposed to silver, zirconium oxide, and silicon oxide nanoparticles as antibacterial agents","authors":"Yeşim Dağlıoğlu,&nbsp;Mustafa Cihan Yavuz,&nbsp;Omer Ertürk,&nbsp;Fuad Ameen,&nbsp;Mehrdad Khatami","doi":"10.1049/mna2.12178","DOIUrl":"https://doi.org/10.1049/mna2.12178","url":null,"abstract":"<p>Antibiotic resistance is one of the biggest public health problems of our time. The nanoparticles are a powerful alternative to these antibiotics. Engineered nanoparticles show toxic effects on bacteria by different mechanisms. The bacteria–cell interaction of engineered nanoparticles exerts their toxic effects through changes in cell wall, cell membrane, and cytoplasm content/density. Thus, death occurs as a result of cell deformation. In this study, the cellular damage of silver nanoparticles, which are known to have strong antibacterial properties, and zirconium oxide and silicon oxide engineering nanoparticles, which are less known, on periodontopathic (<i>Prevotella intermedia</i> and <i>Aggregatibacter actinomycetemcomitans</i>) bacteria, were investigated by ultrastructural changes. The lysis of the cytoplasm and separation of the membrane cytoplasm were observed. Both types of bacteria treated with Ag ENP show more hollow cytoplasm than bacteria treated with the other two nanoparticles.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50152500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro analysis of antibacterial activity against wound pathogens, potential for wound healing, and anti-melanoma properties of biosynthesized zinc oxide nanoparticles","authors":"Ananya Jindaruk,&nbsp;Titiradsadakorn Jaithon,&nbsp;Jiraroj T-Thienprasert,&nbsp;Nattanan Panjaworayan T-Thienprasert","doi":"10.1049/mna2.12177","DOIUrl":"https://doi.org/10.1049/mna2.12177","url":null,"abstract":"<p><i>Staphylococcus aureus</i> is the most common cause of wound infections. Infected wounds increase wound severity and have a slower rate of healing. Moreover, emergence of multiple-drug resistant bacteria such as methicillin-resistant <i>S. aureus</i> (MRSA) limited treatment options. This study was therefore aimed to evaluate antibacterial activity against wound pathogen and wound-healing properties of green synthesized ZnO nanoparticles derived from mangosteen peel crude extract (ZnO-Gm). Moreover, their anti-skin cancer activity was also investigated in vitro. As a result, the ZnO-Gm particles significantly inhibited growth of <i>S. aureus</i> and MRSA with the IC₅₀ values at 0.44 and 0.51 mg/mL, respectively. By performing quantitative reactive oxygen species (ROS) assay, the intracellular ROS in both treated <i>S. aureus</i> and MRSA with ZnO-Gm was found to be significantly elevated. Furthermore, ZnO-Gm exhibited cytotoxic effects via induction of apoptosis on the A375 melanoma cancer cell line, with an IC₅₀ value of 8.91 µg/mL, while not affecting the normal cell line (Vero). In addition, 30 µg/mL of ZnO-Gm could strongly promote wound healing of an epidermal keratinocyte cell line (HaCaT). Consequently, the findings of this study demonstrated that the green synthesized ZnO nanoparticles have potential as antibacterial agents, wound-healing materials, and anti-melanoma agents.</p>","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50143646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}