Micro & Nano Letters最新文献_第5页

In vitro analysis of antibacterial activity against wound pathogens, potential for wound healing, and anti-melanoma properties of biosynthesized zinc oxide nanoparticles 生物合成氧化锌纳米颗粒对伤口病原体的抗菌活性、伤口愈合潜力和抗黑色素瘤特性的体外分析

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-09-24 DOI: 10.1049/mna2.12177

Ananya Jindaruk, Titiradsadakorn Jaithon, Jiraroj T-Thienprasert, Nattanan Panjaworayan T-Thienprasert

{"title":"In vitro analysis of antibacterial activity against wound pathogens, potential for wound healing, and anti-melanoma properties of biosynthesized zinc oxide nanoparticles","authors":"Ananya Jindaruk, Titiradsadakorn Jaithon, Jiraroj T-Thienprasert, Nattanan Panjaworayan T-Thienprasert","doi":"10.1049/mna2.12177","DOIUrl":"https://doi.org/10.1049/mna2.12177","url":null,"abstract":"Staphylococcus aureus is the most common cause of wound infections. Infected wounds increase wound severity and have a slower rate of healing. Moreover, emergence of multiple-drug resistant bacteria such as methicillin-resistant S. aureus (MRSA) limited treatment options. This study was therefore aimed to evaluate antibacterial activity against wound pathogen and wound-healing properties of green synthesized ZnO nanoparticles derived from mangosteen peel crude extract (ZnO-Gm). Moreover, their anti-skin cancer activity was also investigated in vitro. As a result, the ZnO-Gm particles significantly inhibited growth of S. aureus and MRSA with the IC50 values at 0.44 and 0.51 mg/mL, respectively. By performing quantitative reactive oxygen species (ROS) assay, the intracellular ROS in both treated S. aureus and MRSA with ZnO-Gm was found to be significantly elevated. Furthermore, ZnO-Gm exhibited cytotoxic effects via induction of apoptosis on the A375 melanoma cancer cell line, with an IC50 value of 8.91 µg/mL, while not affecting the normal cell line (Vero). In addition, 30 µg/mL of ZnO-Gm could strongly promote wound healing of an epidermal keratinocyte cell line (HaCaT). Consequently, the findings of this study demonstrated that the green synthesized ZnO nanoparticles have potential as antibacterial agents, wound-healing materials, and anti-melanoma agents.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50143646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on the influence of stamping materials on resist flow and the residual layer in thermal nanoimprint lithography 纳米热压印光刻中压印材料对抗蚀剂流动和残余层影响的研究

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-09-22 DOI: 10.1049/mna2.12175

Hong-Wen Sun, Tian-Hua Tang, Jing-Sheng Wang, Li-Jun Gu, Yan-Chun Huang, Ya-Ru Li

引用次数: 0

Nanoencapsulation of oral-pharmaceutical lactoferrin using chitosan and the evaluation of stability against trypsin and pepsin and its antibacterial effect 壳聚糖纳米包埋口服药物乳铁蛋白及其对胰蛋白酶和胃蛋白酶的稳定性评价及其抗菌作用

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-09-13 DOI: 10.1049/mna2.12174

Farzaneh Hedyeloo, Fatemeh Moradian, Mehran Rostami

{"title":"Nanoencapsulation of oral-pharmaceutical lactoferrin using chitosan and the evaluation of stability against trypsin and pepsin and its antibacterial effect","authors":"Farzaneh Hedyeloo, Fatemeh Moradian, Mehran Rostami","doi":"10.1049/mna2.12174","DOIUrl":"https://doi.org/10.1049/mna2.12174","url":null,"abstract":"Lactoferrin (Lf) is an oral-pharmaceutical protein with a variety of biological activities that have attracted the attention of scientists today. In this study, Lf was nano-encapsulated in chitosan biopolymer by ion gelation method with a concentration of 2.5 mg/ml of chitosan and 0.2 and 0.5 mg/ml of Lf and some physicochemical properties were evaluated using zeta potential, DLS, AFM, and SEM. Also, its stability against digestive enzymes such as pepsin and trypsin and its antibacterial effect compare to Lf on Escherichia coli were investigated. The result showed that the mean size of nano-encapsulated lactoferrin (NE-Lf) was 129.6 and 654.6 nm as well as zeta potential, +3.6 and −2.3 mV for 0.2 and 0.5 mg/ml Lf, respectively. SEM and AFM image analysis of NE-Lf showed uniform surfaces, cubic, and homogeneous in shape, as well asdispersion stability of the nanoparticles. NE-Lf had greater stability against the digestion of pepsin and trypsin than Lf. The efficiency of Lf encapsulation in chitosan was 75%. Both NE-Lf and Lf showed that they were able to reduce the growth of E. coli in a dose-dependent manner. EN-Lf was prepared in a simpler way and in lower concentrations of chitosan and Lf than previous methods.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 9-12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50132250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conductive Additives Effects on NCA–LFMP Composite Cathode in Water-Based Binder for High-Safety Lithium-Ion Batteries 导电添加剂对高安全性锂离子电池水性粘结剂NCA-LFMP复合阴极的影响

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-09-05 DOI: 10.3390/micro3030052

Chih-Wei Yang, Meng-Lun Lee, Wen-Ren Liu, Celastin Bebina Thairiyarayar, Wei-Ren Liu, Tsan-Yao Chen, Chi-Young Lee

{"title":"Conductive Additives Effects on NCA–LFMP Composite Cathode in Water-Based Binder for High-Safety Lithium-Ion Batteries","authors":"Chih-Wei Yang, Meng-Lun Lee, Wen-Ren Liu, Celastin Bebina Thairiyarayar, Wei-Ren Liu, Tsan-Yao Chen, Chi-Young Lee","doi":"10.3390/micro3030052","DOIUrl":"https://doi.org/10.3390/micro3030052","url":null,"abstract":"Lithium nickel–cobalt–aluminum oxide (NCA) is a promising cathode material for lithium-ion batteries due to its high energy density of more than 274 mAh/g. However, thermal runaway inhibits its practical applications. Lithium ferromanganese phosphate (LFMP), due to its olivine structure, can effectively stabilize the surface stability of NCA and reduce the exothermic reactions that occur during thermal runaway. LFMP can also inhibit cathode expansion and contraction during charging and discharging. To improve the conductivity of an NCM–LFMP composite electrode, three different conductive additives, namely carbon black, carbon nanotubes (CNTs), and graphene, were introduced into the electrode. Finally, battery safety tests were conducted on 1.1 Ah pouch cells fabricated in the present study. The energy density of the NCA–LFMP 1.1 Ah lithium-ion pouch cells with only 0.16% CNT content reached 224.8 Wh/kg. The CNT–NCA–LFMP pouch cell was also the safest among the cells tested. These results provide a strategy for designing high-energy-density and safe pouch cells for energy storage device applications.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"11 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87818616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geochemistry and Microbiology of Atacamite-Paratacamite Biofilms Floating on Underground Brine and Petroleum Pools in the White Pine Copper Mine, Michigan (USA) 美国密歇根州白松铜矿地下盐水和石油池中漂浮的Atacamite-Paratacamite生物膜的地球化学和微生物学研究

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-08-28 DOI: 10.3390/micro3030051

E. Robbins, M. R. Stanton, Cheryl D. Young

引用次数: 0

Experimental Wear Analysis of Nano-Sized Titania Particles as Additives in Automotive Lubricants 纳米二氧化钛颗粒作为汽车润滑油添加剂的实验磨损分析

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-08-21 DOI: 10.3390/micro3030050

Á. Szabó, Á. Tóth, Hebah Abdallah, H. Hargitai

{"title":"Experimental Wear Analysis of Nano-Sized Titania Particles as Additives in Automotive Lubricants","authors":"Á. Szabó, Á. Tóth, Hebah Abdallah, H. Hargitai","doi":"10.3390/micro3030050","DOIUrl":"https://doi.org/10.3390/micro3030050","url":null,"abstract":"This study focuses on the wear effects of nano-sized titania as a potential engine lubricant additive. Titanium dioxide nanoparticles have promising wear-reducing properties and significant tribological potential. In this article, titania nanoparticles were homogenized in Group III automotive oil at five different concentrations (0.1; 0.2 … 0.5 wt%). The nanodoped oil samples were tested on a linear oscillating tribometer with oil circulation. Based on the tribological results, titania nanoparticles increased friction by 20–32% but can reduce the wear area by up to 32%. According to the confocal microscopic examination, wear volume can be reduced by up to 57% with titania nanoparticles. Titania nanoparticles improved the repeatability of tribological measurements. A scanning electron microscopy examination of the wear track revealed that the characteristic wear of the tribological system was abrasive, but a significant amount of adhesive wear was also observed. Energy dispersive X-ray spectroscopy analysis found that the nanoparticles fill the deeper trenches of the wear. The worn surface uniformly contains TiO2 particles and the quantified normalized titanium concentration was between 0.56 and 0.62%.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"76 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81240367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Matrix Effect of Properties of Au, ZnO and Eu2O3: Silica, Titania and Alumina Matrices Au, ZnO和Eu2O3:二氧化硅，二氧化钛和氧化铝基体性能的基体效应

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-08-19 DOI: 10.3390/micro3030049

Carlos Díaz, O. Cifuentes-Vaca, M. Valenzuela

引用次数: 0

Highly Sensitive Sensor for the Determination of Riboflavin Using Thionine Coated Cadmium Selenide Quantum Dots Modified Graphite Electrode 硫氨酸包覆硒化镉量子点修饰石墨电极测定核黄素的高灵敏度传感器

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-08-13 DOI: 10.3390/micro3030048

A. Kalaivani, R. Suresh Babu, S. Sriman Narayanan

{"title":"Highly Sensitive Sensor for the Determination of Riboflavin Using Thionine Coated Cadmium Selenide Quantum Dots Modified Graphite Electrode","authors":"A. Kalaivani, R. Suresh Babu, S. Sriman Narayanan","doi":"10.3390/micro3030048","DOIUrl":"https://doi.org/10.3390/micro3030048","url":null,"abstract":"In this paper, the electrochemical non-enzymatic detection of Riboflavin (RF) was proposed based on its catalytic reduction in a Thionine-coated Cadmium Selenide Quantum dots (TH@CdSe QDs)-modified paraffin wax-impregnated graphite electrode (PIGE) that was prepared using a novel approach. The synthesized TH@CdSe QDs were confirmed by UV-Vis spectroscopy, Confocal Raman Microscopy and High Resolution Transmission Electron Microscopy (HRTEM) studies. The electrochemical response of the TH@CdSe QDs-modified PIGE was studied by cyclic voltammetry. The voltammetric response of RF at the TH@CdSe QDs-modified PIGE showed higher current than the bare PIGE. Under optimum conditions, the electrocatalytic reduction currents of RF was found to be linearly related to its concentration over the range of 1.6 × 10−7 M to 1.4 × 10−4 M with a detection limit of 53 × 10−9 M (S/N = 3). The TH@CdSe QDs-modified PIGE was utilized as an amperometric sensor for the detection of RF in flow systems was performed by carrying out hydrodynamic and chronoamperometric experiments. The TH@CdSe QDs-modified PIGE showed very good stability and a longer shelf life. The applicability of the fabricated electrode was justified by the quantification of RF in commercial tablets.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"48 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80626316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Self-trigger and on-demand drug delivery system based on TiO2 nanotube arrays and its drug release behaviour 基于TiO2纳米管阵列的自触发按需给药系统及其药物释放行为

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-08-02 DOI: 10.1049/mna2.12173

Tao Zhang, Nannan Liu, Chunling Xie, Xiufeng Xiao

{"title":"Self-trigger and on-demand drug delivery system based on TiO2 nanotube arrays and its drug release behaviour","authors":"Tao Zhang, Nannan Liu, Chunling Xie, Xiufeng Xiao","doi":"10.1049/mna2.12173","DOIUrl":"https://doi.org/10.1049/mna2.12173","url":null,"abstract":"The foundation of drug delivery systems based on titanium dioxide nanotube arrays has become an important means to increase the drug release performance of bone implantation materials. However, most of the conventional platforms have some disadvantages, such as large sudden release, uncontrollable, unintelligent, or not on-demand drug release process. Herein, the authors develop a unique self-triggering drug release system (SDDS), utilizing the advantages of 1-Tetradecanol (TD), such as decent biocompatibility, a phase transition temperature of 37.8°C, and the inexistence of complex chemical reaction process. The establishment of the platform can make a large amount of the anti-inflammatory drug (ibuprofen, IBU) released when the body or the affected area is inflamed, that is, when the temperature rises. Conversely, only a small amount or no drug is released when there is no inflammation, thereby achieving self-trigger release and on-demand release. The experimental results show that the system combines good self-trigger release properties, release sensitivity, drug release cycle, and low selectivity to the loaded drugs.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"18 8","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/mna2.12173","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50128492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microfluidic System for Cell Mixing and Particle Focusing Using Dean Flow Fractionation 采用迪安流分馏的微流体混合和颗粒聚焦系统

IF 1.3 4区材料科学

Micro & Nano Letters Pub Date : 2023-07-31 DOI: 10.3390/micro3030047

Alexander Wiede, O. Stranik, A. Tannert, U. Neugebauer

{"title":"Microfluidic System for Cell Mixing and Particle Focusing Using Dean Flow Fractionation","authors":"Alexander Wiede, O. Stranik, A. Tannert, U. Neugebauer","doi":"10.3390/micro3030047","DOIUrl":"https://doi.org/10.3390/micro3030047","url":null,"abstract":"Recent developments in the field of additive manufacturing processes have led to tremendous technological progress and opened directions for the field of microfluidics. For instance, new flexible materials for 3D printing allow the substitution of polydimethylsiloxane (PDMS) in microfluidic prototype development. Three-dimensional-printed microfluidic components open new horizons, in particular for the automated handling of biological cells (e.g., eukaryotic cells or bacteria). Here, we demonstrate how passive mixing and passive separation processes of biological cells can be realized using 3D printing concepts for rapid prototyping. This technique facilitates low-cost experimental setups that are easy to modify and adopt for specific detection and diagnostic purposes. In particular, printing technologies based on fused deposition modeling and stereolithography are used and their realization is discussed. Additive technologies enable the fabrication of multiplication mixers, which overcome shortcomings of current pillar or curve-based techniques and enable efficient mixing, also of biological cells without affecting viability. Using standard microfluidic components and state-of-the art 3D printing technologies, we realize a separation system based on Dean flow fragmentation without the use of PDMS. In particular, we describe the use of a 3D-printed helix for winding a capillary for particle flow and a new chip design for particle separation at the outlet. We demonstrate the functionality of the system by successful isolation of ~12 µm-sized particles from a particle mixture containing large (~12 µm, typical size of eukaryotic cells) and small (~2 µm, typical size of bacteria or small yeasts) particles. Using this setup to separate eukaryotic cells from bacteria, we could prove that cell viability is not affected by passage through the microfluidic systems.","PeriodicalId":18398,"journal":{"name":"Micro & Nano Letters","volume":"282 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76255450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0