Medical Journal of the Islamic Republic of Iran最新文献

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The Role of Tourism in Enhancing Domains of Health for Seniors: A Scoping Review. 旅游在促进老年人健康领域中的作用:范围审查。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-13 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.40
Vali Bahrevar, Nasibeh Zanjari, Saeed Hosseini, Mojtaba Fattahi Ardakani, Sadegh Kazemi
{"title":"The Role of Tourism in Enhancing Domains of Health for Seniors: A Scoping Review.","authors":"Vali Bahrevar, Nasibeh Zanjari, Saeed Hosseini, Mojtaba Fattahi Ardakani, Sadegh Kazemi","doi":"10.47176/mjiri.39.40","DOIUrl":"10.47176/mjiri.39.40","url":null,"abstract":"<p><strong>Background: </strong>Old age is one of the critical stages of human life, encompassing a significant portion of people's lives in society. During this period, the elderly face various challenges, such as health conditions. As one of the important sectors, the tourism industry has gained considerable popularity among the elderly for promoting health. Therefore, this review study was conducted to examine the role of tourism in the health status of the elderly.</p><p><strong>Methods: </strong>This scoping review was conducted according to Arksey and O'Malley (2005). In this scoping review, a systematic search was conducted for studies with any type of design on the role, impact, and consequences of tourism on the elderly. The search covered studies in both Persian and English languages from 1984 to 2023 across databases and search engines-including PubMed, Scopus, Web of Science, IranMedex, IRANDOC, Google Scholar, MAGIRAN, and SID-using the keywords \"tourism, old person, senior, aged, aging, elderly, older adults, old age\" and their Persian equivalents.</p><p><strong>Results: </strong>Out of 7454 studies identified in the initial search, 23 articles on aging and tourism were finally reviewed based on the inclusion criteria. The studies investigated the role and impact of tourism on health in 3 ways: mixed methods, quantitative, and qualitative. In qualitative studies, the experiences of elderly people with tourism were examined, while quantitative studies explored tourism's predictive role as an independent variable and its correlation with various dimensions of health. The results of the quantitative studies showed that tourism improved the physical health of the elderly. The mean scores for cognitive function, daily activities, and vitality were reported to be higher among elderly tourists compared to nontourists. Additionally, the quality of life and well-being scores of elderly individuals who engaged in tourism were significantly higher compared to those who did not. Tourism experiences for the elderly were often associated with better life satisfaction, a sense of peace, and purpose in life.</p><p><strong>Conclusion: </strong>Based on the results, tourism can improve the health and quality of life of the elderly. Given the importance of tourism, it is recommended that the tourism industry and its marketing for the elderly be prioritized as a target group. Additionally, to promote the tourism industry, special attention should be given to the specific needs and welfare issues of the elderly.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"40"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internet of Things in Medical Education: A Systematic Mapping Review. 医学教育中的物联网:一个系统的地图综述。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.39
Ali Behmanesh, Roshanak Shams, Samira Soleimanpour, Mohammad Ali Fazeli, Mohammad Hosseinzadeh Davarzani
{"title":"Internet of Things in Medical Education: A Systematic Mapping Review.","authors":"Ali Behmanesh, Roshanak Shams, Samira Soleimanpour, Mohammad Ali Fazeli, Mohammad Hosseinzadeh Davarzani","doi":"10.47176/mjiri.39.39","DOIUrl":"10.47176/mjiri.39.39","url":null,"abstract":"<p><strong>Background: </strong>The Internet of Things (IoT) has introduced new possibilities for revolutionizing medical education and training. This study aimed to conduct a systematic mapping review of existing research to identify and map current advancements in IoT in medical education. The study sought to address key research questions regarding trends and activities in IoT development within this field.</p><p><strong>Methods: </strong>The systematic mapping review explored the intersection of IoT and medical education by systematically collecting, categorizing, and synthesizing relevant studies. We conducted a keyword search in major online scientific databases, and 285 papers were initially retrieved from IEEE, PubMed, Scopus, and Web of Science. After removing duplicates, 204 unique papers were identified. A 2-stage selection process based on predefined criteria narrowed this down to 28 eligible papers. Data extraction from these studies highlighted trends in research development and geographical distribution.</p><p><strong>Results: </strong>The analysis revealed that most publications on IoT systems in medical education were peer-reviewed journal papers (79%), with conference proceedings making up 21%. Thirteen countries contributed to the research, with the United States leading. The studies included pilot projects, laboratory experiments, and feasibility studies. IoT devices and sensors were applied in various areas, such as curriculum development, clinical skills training, patient simulation, telemedicine, and distance learning. While general medicine saw the most IoT applications, other medical disciplines also utilized these technologies.</p><p><strong>Conclusion: </strong>Our findings have shed light on the transformative potential of wearable technology and IoT applications in enhancing educational outcomes and practices. The versatility of IoT devices and sensors across multiple domains within medical education highlights their capacity to revolutionize teaching, learning, research, and clinical practice. Our findings catalyze medical education leaders and policymakers to delve deeper into the possibilities offered by IoT, ultimately leading to improved educational experiences and outcomes.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"39"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reducing The Environmental Footprint of Unnecessary Medical Interventions. 减少不必要的医疗干预的环境足迹。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-11 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.38
Mohammad Zakaria Pezeshki
{"title":"Reducing The Environmental Footprint of Unnecessary Medical Interventions.","authors":"Mohammad Zakaria Pezeshki","doi":"10.47176/mjiri.39.38","DOIUrl":"10.47176/mjiri.39.38","url":null,"abstract":"","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"38"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Inspiratory Muscle Training Effect Compared With Diaphragmatic Breathing in Respiratory Parameters in Amyotrophic Lateral Sclerosis Patients: A Randomized Controlled Trial. 肌萎缩性侧索硬化症患者呼吸参数中吸气肌训练与膈肌呼吸效果的评价:一项随机对照试验。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-10 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.37
Maryam Sadat Mirenayat, Atefeh Fakharian, Melika Valizadeh, Mohsen Abedi, Somayeh Sadeghi, Reyhaneh Zahiri, Bahram Haghi Ashtiani, Fatemeh Masaebi, Babak Zamani
{"title":"Evaluation of Inspiratory Muscle Training Effect Compared With Diaphragmatic Breathing in Respiratory Parameters in Amyotrophic Lateral Sclerosis Patients: A Randomized Controlled Trial.","authors":"Maryam Sadat Mirenayat, Atefeh Fakharian, Melika Valizadeh, Mohsen Abedi, Somayeh Sadeghi, Reyhaneh Zahiri, Bahram Haghi Ashtiani, Fatemeh Masaebi, Babak Zamani","doi":"10.47176/mjiri.39.37","DOIUrl":"10.47176/mjiri.39.37","url":null,"abstract":"<p><strong>Background: </strong>Many patients with amyotrophic lateral sclerosis (ALS) experience respiratory failure. The use of respiratory muscle training exercises can improve the respiratory function of these patients. This study aimed to evaluate the effect of inspiratory muscle training (IMT) on respiratory muscle function in ALS patients.</p><p><strong>Methods: </strong>In the current randomized controlled clinical trial study, 22 patients were randomly divided into intervention (n = 11) and control groups (n = 11). In the control group, patients used only chest-opening training and diaphragm exercises. Patients in the intervention group used IMT in addition to controlled exercises (chest opening training and diaphragm exercises). Respiratory function by spirometry and monitoring of maximum inspiratory and expiratory pressure, functional capacity with a 6-minute walk test, and arterial blood gases were also assessed by ABG analysis at baseline and after 8 weeks. A comparative analysis of variables was performed with a student t-test, considering type 1 error (α = 0.05) using SPSS 27 software.</p><p><strong>Results: </strong>The indexes included maximal inspiratory pressure (PImax) (<i>P</i> = 0.000) and maximal expiratory pressures PEmax (<i>P</i> = 0.002). The strength of breathing muscles index (S-index) (<i>P</i> = 0.002) had a significant increase before and after rehabilitation in both groups (<i>P</i> ˂ 0.05). In intergroup analysis, the only factor with a significant increase was PImax (<i>P</i> = 0.019).</p><p><strong>Conclusion: </strong>The use of IMT, along with chest opening training and diaphragm exercises, can cause a relative improvement of the respiratory muscles' function indexes, especially PImax in ALS patients. More clinical trials are required.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Memory Function in Euthymic Patients with Bipolar I Disorder: A Cross-Sectional Study of Clinical and Demographic Correlates. 双相I型心境障碍者的记忆功能:临床和人口学相关性的横断面研究。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.36
Amir Shabani, Seyed Vahid Shariat, Maryam Noroozian, Morteza Naserbakht, Maryam Mohammadi
{"title":"Memory Function in Euthymic Patients with Bipolar I Disorder: A Cross-Sectional Study of Clinical and Demographic Correlates.","authors":"Amir Shabani, Seyed Vahid Shariat, Maryam Noroozian, Morteza Naserbakht, Maryam Mohammadi","doi":"10.47176/mjiri.39.36","DOIUrl":"10.47176/mjiri.39.36","url":null,"abstract":"<p><strong>Background: </strong>Memory is one of the most affected cognitive domains in patients with Bipolar I Disorder, even during periods of euthymia. This study aimed to investigate the relationship between certain clinical and demographic variables and the domains of memory function in euthymic bipolar I patients.</p><p><strong>Methods: </strong>This cross-sectional study included 100 patients who were confirmed to be euthymic at the time of the research, as indicated by Hamilton Depression Rating Scale scores (HDRS <7) and Young Mania Rating Scale scores (YMRS <12). Recruitment was conducted between March 2021 and March 2022. Their demographic data were collected, and all participants were evaluated for psychiatric comorbidities using the Structured Clinical Interview for DSM-5 (SCID-5-CV). Memory function was assessed using the Wechsler Memory Scale-3rd edition (WMS-3). The correlation between memory function and demographic and clinical variables was analyzed.</p><p><strong>Results: </strong>The Wechsler Memory Scale total score was significantly associated with the number of hospitalizations, education level, and the number of depressive episodes. Notably, each additional hospitalization (β = -21.70 ± 8.18) and depressive episode (β = -23.36 ± 6.86) corresponded to a marked reduction in memory performance. The regression model demonstrated a robust fit, with an R-square value of 0.68.</p><p><strong>Conclusion: </strong>Memory function is significantly correlated with the number of hospitalizations, level of education, and the number of previous depressive episodes in euthymic Bipolar I patients. This study underscores the importance of these factors in understanding and preventing memory impairment in this patient group.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"36"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Right to Freeze Oocyte for Women in Iranian Fertility Centers: A Qualitative Study. 伊朗生育中心妇女冷冻卵母细胞的权利:一项定性研究
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.35
Mansoureh Moaya, Shadab Shahali, Minoor Lamyian, Alireza Milanifar, Seyed-Mohammad Azin
{"title":"The Right to Freeze Oocyte for Women in Iranian Fertility Centers: A Qualitative Study.","authors":"Mansoureh Moaya, Shadab Shahali, Minoor Lamyian, Alireza Milanifar, Seyed-Mohammad Azin","doi":"10.47176/mjiri.39.35","DOIUrl":"10.47176/mjiri.39.35","url":null,"abstract":"<p><strong>Background: </strong>With the advancements in fertility preservation technology, such as egg freezing, women could now preserve their gametes for potential future parenthood. It is important to explore how the needs of women are addressed and supported throughout the egg-freezing process. By investigating the experiences of research participants, we aimed to identify how reproductive rights are interpreted for egg-freezing applicants in Iranian infertility centers.</p><p><strong>Methods: </strong>In this qualitative study, 16 service providers and 5 egg-freezing applicants in infertility treatment centers in Iran were interviewed. Data were collected through semi-structured interviews. All interviews were recorded and after transcription, conventional qualitative content analysis was used for data analysis.</p><p><strong>Results: </strong>Issues related to specific requirements for evaluating the reproductive rights of egg-freezing applicants included the following: the right to preserve fertility, the right to access psychological support services,the right to decide the fate of the oocyte, the right to trust and privacy, and the right to one's own body.</p><p><strong>Conclusion: </strong>Women had the right to decide the fate of their eggs and choose to preserve them for future uses. Service providers played a role by offering comprehensive information about the egg-freezing process, considering applicants' requests, and offering psychological support to those interested. It seemed, trusting and using this emerging technology, users can protect their reproductive rights by preventing infertility in the future.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation and Comparison of Treatment Response and In-Hospital Prognosis of COVID-19-Related Guillain-Barre Syndrome with Non-COVID-19 Patients. covid -19相关格林-巴利综合征与非covid -19患者治疗反应及院内预后的评价与比较
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-04 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.34
Behnaz Ansari, Niloofar Rezaei, Mohsen Kheradmand, Mohammad Amin Najafi, Keivan Basiri
{"title":"Evaluation and Comparison of Treatment Response and In-Hospital Prognosis of COVID-19-Related Guillain-Barre Syndrome with Non-COVID-19 Patients.","authors":"Behnaz Ansari, Niloofar Rezaei, Mohsen Kheradmand, Mohammad Amin Najafi, Keivan Basiri","doi":"10.47176/mjiri.39.34","DOIUrl":"10.47176/mjiri.39.34","url":null,"abstract":"<p><strong>Background: </strong>The coronavirus disease 2019 (COVID-19) outbreak has caused significant health and social impacts worldwide. Severe acute respiratory syndrome coronavirus 2, the virus responsible for COVID-19, can lead to neurological symptoms, including Guillain-Barré syndrome (GBS). This study aimed to compare the clinical manifestations, electrophysiological characteristics, degree of disability, and treatment outcomes of GBS patients with COVID-19 (COVID-19-related GBS) with GBS patients without COVID-19.</p><p><strong>Methods: </strong>This retrospective cross-sectional multicenter study investigated the clinical characteristics and outcomes of GBS patients with a history of COVID-19. A total of 60 patients with GBS and a history of COVID-19 were included in the COVID-19 group, while 56 patients with GBS without COVID-19 were included in the control group. Demographic, clinical, therapeutic, and prognostic data were compared between the 2 groups.</p><p><strong>Results: </strong>The COVID-19 patients were older (56.2 ± 16.8 vs 47.46 ± 19.25; <i>P</i> = 0.01), and there was no sex difference between the 2 groups. The most frequent electrophysiological type was acute inflammatory demyelinating polyradiculoneuropathy (55% and 41%) in both groups. Although almost half of the patients in both groups were admitted to the intensive care unit (ICU), the group of COVID-19 patients required mechanical ventilation more (16.6% vs 0%; <i>P</i> < 0.001). Also, the COVID-19 group had more length of ICU stay (<i>P</i> < 0.001). Although some electrophysiological differences were found (acute motor axonal neuropathy was more frequent in the non-COVID-19 group), The analysis did not show any difference in the response to treatment scores based on Phenotype, type of treatment, or electrophysiological pattern between the 2 groups of patients.</p><p><strong>Conclusion: </strong>GBS in COVID-19 patients may have different manifestations and electrophysiological patterns, but the response to treatment and in-hospital prognosis were not different compared with GBS in non-COVID-19 patients.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"34"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes In The Retinal Nerve Fiber Layer In Patients With Parkinson's Disease, Progressive Supranuclear Palsy, And Multiple System Atrophy With And Without Dementia. 帕金森病、进行性核上性麻痹和多系统萎缩伴或不伴痴呆患者视网膜神经纤维层的变化
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-03-03 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.33
Peyman Daraei, Morteza Taheri
{"title":"Changes In The Retinal Nerve Fiber Layer In Patients With Parkinson's Disease, Progressive Supranuclear Palsy, And Multiple System Atrophy With And Without Dementia.","authors":"Peyman Daraei, Morteza Taheri","doi":"10.47176/mjiri.39.33","DOIUrl":"10.47176/mjiri.39.33","url":null,"abstract":"<p><strong>Background: </strong>Several studies have evaluated RNFL thickness in PD, with only a few on other Parkinsonian syndromes. There is insufficient information on the pattern of changes in these patients who have dementia. Therefore, the present study examined the RNFL thickness in Parkinsonism patients with and without dementia.</p><p><strong>Methods: </strong>In this cross-sectional study, all patients diagnosed with PD, MSA, and PSP from March 2017 to February 2019 were evaluated. The severity of the disease and the presence of dementia were determined using the UPDRS and MMSE tests, respectively. The thickness of the RNFL was measured in the superior, inferior, nasal, and temporal quadrants using the 3D-OCT 1000 Mark II. Statistical methods, including the independent t-test, one-way analysis of variance (ANOVA), and the Pearson correlation coefficient, were used to analyze the data at a significance level of 0.05 using SPSS statistical software.</p><p><strong>Results: </strong>Fifty-three patients were examined. The mean age and mean UPDRS showed a significant difference between the groups, while gender and disease duration did not show. The mean RNFL thickness in the nasal sector had a significant difference among the three groups, with a thinner thickness in patients with MSA (<i>P</i><0.05). Patients with PD, PSP, and MSA with dementia showed a significantly greater reduction in RNFL thickness in the upper and temporal quadrants, nasal quadrant, and upper and temporal quadrants compared to PD, PSP, and MSA without dementia, respectively (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Evaluating RNFL can be useful in predicting ocular involvement. Once validated in further studies, OCT may serve as a biomarker for predicting the presence or progression of movement disorders. OCT may also assist in predicting the presence of dementia in these patients by reflecting a more significant reduction in RNFL thickness compared to patients without dementia.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Clinical Outcomes after Toe Amputation and Toe-Sparing Surgery in Patients with Diabetic Foot Ulcer. 糖尿病足溃疡患者脚趾截肢与保留脚趾手术的临床疗效比较。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-02-27 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.32
Ali Yeganeh, Alireza Kalantar Motamed, Salar Baghbani, Sahand Cheraghiloohesara, Milad Gorgani, Mohammad Soleimani
{"title":"Comparing Clinical Outcomes after Toe Amputation and Toe-Sparing Surgery in Patients with Diabetic Foot Ulcer.","authors":"Ali Yeganeh, Alireza Kalantar Motamed, Salar Baghbani, Sahand Cheraghiloohesara, Milad Gorgani, Mohammad Soleimani","doi":"10.47176/mjiri.39.32","DOIUrl":"10.47176/mjiri.39.32","url":null,"abstract":"<p><strong>Background: </strong>Diabetic ulceration leads to amputation in up to 85% of cases. Managing a diabetic ulcer requires an expert team to prevent wound progression and apply proper supportive procedures, decreasing the risk of amputation. This study aimed to compare the clinical efficacy of toe-sparing surgery and toe amputation in patients with diabetic foot ulcers.</p><p><strong>Methods: </strong>This cohort evaluated 54 consecutive patients with Diabetes Mellitus and chronic ulcers in the lower extremities. The patients were treated by bone resection with preserving toe and soft tissue or complete toe amputation. They were followed up for one year. We evaluated the relative risk for re-ulceration of the same toe, ulcers in other parts, increased levels of hemoglobin A1c (HbA1c), and infection between the two groups.</p><p><strong>Results: </strong>The re-ulceration rate at the same toe was 12.9% in the toe amputation and 39.1% in the toe-sparing group (<i>P</i> < 0.001). The prevalence of other amputations in the toe amputation and toe-sparing surgery groups was 29.0% and 17.4%, respectively (<i>P</i> < 0.001). However, the infection rate was lower in the toe-sparing group (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>The re-ulceration rate was lower after toe amputation, and the infection rate was higher in the toe amputation group.</p>","PeriodicalId":18361,"journal":{"name":"Medical Journal of the Islamic Republic of Iran","volume":"39 ","pages":"32"},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12138757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biochemical and Histopathological Alterations Induced by Tramadol. 曲马多诱导的生化和组织病理学改变。
Medical Journal of the Islamic Republic of Iran Pub Date : 2025-02-26 eCollection Date: 2025-01-01 DOI: 10.47176/mjiri.39.31
Husam Abazid, Nour Alabbas, Alaa Hammad, Osama I Ramadan, Esraa Ebraheem Al Jomaa, Mumen Fathi Amer, F Scott Hall
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