Mayo Clinic proceedings最新文献

{"title":"Early Rhythm Control Therapy in Patients With Atrial Fibrillation—Kidney Function Matters","authors":"Mikhail S. Dzeshka MD, Alena Shantsila MD, PhD, Gregory Y.H. Lip MD, Eduard Shantsila MD, PhD","doi":"10.1016/j.mayocp.2025.02.014","DOIUrl":"10.1016/j.mayocp.2025.02.014","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 599-602"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifetime Risk of Self-Reported Physician-Diagnosed Osteoarthritis in the United States","authors":"Yejin Mok PhD, MPH , Yingying Sang MS , Jyotsna Ghosh MD , Matthew J. Best MD , Kunihiro Matsushita MD, PhD","doi":"10.1016/j.mayocp.2025.01.002","DOIUrl":"10.1016/j.mayocp.2025.01.002","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 751-753"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mayo Brothers Statue at Rochester Civic Center by James Earle Fraser","authors":"Margaret R. Wentz BA","doi":"10.1016/j.mayocp.2025.02.008","DOIUrl":"10.1016/j.mayocp.2025.02.008","url":null,"abstract":"<div><div>Art is integrated into the Mayo Clinic environment. Since the original Mayo Clinic Building was finished in 1914, many pieces have been donated or commissioned for patients and staff to enjoy. Each issue of <em>Mayo Clinic Proceedings</em> features a work of art (as interpreted by the author) that is displayed in a building on or near the grounds of Mayo Clinic campuses.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 759-760"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"28-Year-Old Woman With Undifferentiated Spells","authors":"Mitra Moazzami MD, MPH ,&nbsp;Sneha Mohan MD ,&nbsp;Aoife M. Egan MD, PHD","doi":"10.1016/j.mayocp.2024.04.019","DOIUrl":"10.1016/j.mayocp.2024.04.019","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 735-740"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiography Screening of Consecutive Patients With Portal Hypertension Referred to Mayo Clinic for Liver Transplant Evaluation","authors":"Charles D. Burger MD ,&nbsp;Hollie Saunders MD ,&nbsp;David O. Hodge MS ,&nbsp;Robert E. Safford MD, PhD ,&nbsp;Scott A. Helgeson MD ,&nbsp;John E. Moss MD ,&nbsp;Hilary M. DuBrock MD ,&nbsp;Rodrigo Cartin-Ceba MD ,&nbsp;Hector R. Cajigas MD ,&nbsp;Michael J. Krowka MD","doi":"10.1016/j.mayocp.2024.08.011","DOIUrl":"10.1016/j.mayocp.2024.08.011","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the prevalence of portopulmonary hypertension in patients referred for liver transplant evaluation.</div></div><div><h3>Methods</h3><div>Medical records were reviewed for 986 consecutive patients referred for liver transplant evaluation who were screened for pulmonary hypertension with echocardiography from February 1, 2021, to January 31, 2022, across 3 liver transplant centers.</div></div><div><h3>Results</h3><div>Of 934 patients eligible for analysis, mean (SD) age was 57 (11) years, 558 (59.7%) were men, and 859 (92.0%) were White. Alcoholic cirrhosis and nonalcoholic steatohepatitis represented 640 (68.5%) of the liver diseases. Right ventricular systolic pressure estimated by echocardiography was 35 mm Hg or greater in 147 (15.7%) and less than 35 mm Hg in 475 (50.9%; unable to estimate in 312 [33.4%]). Right-sided heart catheterization was performed in 42 (4.5%) patients; hemodynamic profiles revealed that 12 (28.6%) did not have pulmonary hypertension, 15 (35.7%) had postcapillary venous pulmonary hypertension, 7 (16.7%) had portopulmonary hypertension, 6 (14.3%) had unclassifiable pulmonary hypertension, and 2 (4.8%) had combined pre- and postcapillary pulmonary hypertension.</div></div><div><h3>Conclusion</h3><div>The percentage of portopulmonary hypertension in patients referred for liver transplant was considerably lower, 7 of 934 (0.7%), than in previous studies, but the reason was unclear.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 668-679"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acrokeratosis Paraneoplastica Due to Monoclonal Gammopathy","authors":"Aiman J. Faruqi MD, MS ,&nbsp;Giang Huong Nguyen MD, DPhil ,&nbsp;Joselle Cook MBBS","doi":"10.1016/j.mayocp.2025.01.017","DOIUrl":"10.1016/j.mayocp.2025.01.017","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 747-748"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Pressure Time in Target Range Within 24 Hours and Cardiovascular Diseases and Mortality: Perspectives From a Real-World Cohort Study","authors":"Xue Tian PhD ,&nbsp;Yijun Zhang PhD ,&nbsp;Shuohua Chen MD ,&nbsp;Xue Xia PhD ,&nbsp;Qin Xu PhD ,&nbsp;Yi Wang MD ,&nbsp;Shouling Wu MD ,&nbsp;Anxin Wang PhD","doi":"10.1016/j.mayocp.2024.08.012","DOIUrl":"10.1016/j.mayocp.2024.08.012","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the association of 24-hour, daytime, and nighttime ambulatory systolic blood pressure (SBP) time in target range (TTR) with the risk of cardiovascular disease (CVD) and mortality in real-world settings.</div></div><div><h3>Patients and Methods</h3><div>Data were obtained from the Kailuan study. Systolic blood pressure TTR was calculated using linear interpolation, with 110 to 140 mm Hg as the target range. Cox regressions were performed to assess the associations of SBP TTR with outcomes.</div></div><div><h3>Results</h3><div>Among 5099 participants in this analysis, 396 cases of CVD (7.77%) and 490 cases of all-cause mortality (9.61%) occurred during a median follow-up of 6.96 years. After multivariable adjustment, each 1-SD increment in 24-hour SBP TTR was associated with an 11% lower risk of CVD (hazard ratio [HR], 0.89; 95% CI, 0.79 to 0.99; <em>P</em>=.008) and all-cause mortality (HR, 0.89; 95% CI, 0.81 to 0.98; <em>P</em>=.01). Consistently, each 1-SD increment in daytime SBP TTR was associated with 14% lower risk of CVD (HR, 0.86; 95% CI, 0.78 to 0.95; <em>P</em>=.005) and 13% lower risk of all-cause mortality (HR, 0.87; 95% CI, 0.79 to 0.95; <em>P</em>=.003). However, the associations for nighttime SBP TTR did not reach statistically significant levels.</div></div><div><h3>Conclusion</h3><div>Higher SBP TTR was associated with lower risk of CVD and mortality among Chinese adults in real-world settings. Efforts to attain SBP within 110 to 140 mm Hg over time may be an effective strategy to prevent CVD.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 657-667"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In the Limelight: April 2025","authors":"Karl A. Nath MBChB (Editor-in-Chief)","doi":"10.1016/j.mayocp.2025.02.017","DOIUrl":"10.1016/j.mayocp.2025.02.017","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 587-589"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advance Insulin Injection Technique and Education With FITTER Forward Expert Recommendations","authors":"David C. Klonoff MD, FACP, FRCP (Edin), Fellow AIMBE ,&nbsp;Lori Berard RN, CDE ,&nbsp;Denise Reis Franco MD ,&nbsp;Sandro Gentile MD, PhD ,&nbsp;Olga Victoria Gomez MD ,&nbsp;Zanariah Hussein MBBS, MRCP ,&nbsp;Akshay B. Jain MD ,&nbsp;Sanjay Kalra DM ,&nbsp;Henry Anhalt DO ,&nbsp;Julia K. Mader MD ,&nbsp;Eden Miller DO ,&nbsp;Miguel Augusto O’Meara MD ,&nbsp;Michelle Robins ANP ,&nbsp;Felice Strollo MD, PhD ,&nbsp;Hirotaka Watada MD, PhD ,&nbsp;Lutz Heinemann PhD","doi":"10.1016/j.mayocp.2025.01.004","DOIUrl":"10.1016/j.mayocp.2025.01.004","url":null,"abstract":"<div><div>Injectable insulin therapy is a valuable therapeutic option for millions of people with diabetes worldwide. However, many people with diabetes undergoing insulin therapy experience suboptimal outcomes and/or have complications because of inadequate injection technique and training. Practical, current, evidence-based recommendations are mandatory for primary care practitioners and diabetes specialists alike to address unmet needs in insulin injection technique, education, and consequent outcomes. The most recent global insulin injection technique best practices were published in 2016 by the Forum for Injection Technique and Therapy Expert Recommendations (FITTER). While injection technique efforts in different regions have reflected some developments since 2016, a global effort was warranted to comprehensively capture new evidence and modern expert perspectives. In this article, we share the output of the “FITTER Forward” initiative, authored by 16 diabetes specialists from 13 countries who met virtually in 2023-2024. FITTER Forward provides an updated rationale for the importance of proper injection technique training and its impact on diabetes management. The FITTER Forward recommendations are organized for use in clinical practice and include 4 sections describing (1) the foundational science informing injection device design, experiences, and outcomes, (2) proper injection technique procedures for insulin pens and syringes from insulin storage to needle disposal, (3) lipodystrophy risk reduction, with a focus on lipohypertrophy, and (4) structured injection technique training programs for people with diabetes. Overall, FITTER Forward aims to better equip health care professionals to advance diabetes care by empowering people with diabetes and their caregivers to correctly and safely deliver insulin.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 682-699"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Composite Gangliocytoma/Neuroma and Neuroendocrine Tumor (CoGNET)","authors":"Jorge Torres-Mora MD,&nbsp;Rumeal D. Whaley MD,&nbsp;Lori A. Erickson MD","doi":"10.1016/j.mayocp.2025.02.011","DOIUrl":"10.1016/j.mayocp.2025.02.011","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 4","pages":"Pages 757-758"},"PeriodicalIF":6.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}