Mayo Clinic proceedings最新文献

{"title":"Lymphoma Involving Skeletal Muscles: A Rare Mimic of Myositis","authors":"Thapat Wannarong MD , Andrew L. Feldman MD , Margherita Milone MD, PhD","doi":"10.1016/j.mayocp.2025.03.023","DOIUrl":"10.1016/j.mayocp.2025.03.023","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1288-1289"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Health Care Through Quality and Safety","authors":"Kannan Ramar MD, MBA ,&nbsp;Amy S. Oxentenko MD ,&nbsp;Sean C. Dowdy MD","doi":"10.1016/j.mayocp.2025.04.012","DOIUrl":"10.1016/j.mayocp.2025.04.012","url":null,"abstract":"<div><div>In high-performing health care institutions, delivering high-quality care and ensuring patient safety are core priorities. The transformation of health care using quality and safety end points is driven by a commitment to patient-centered care, continuous improvement, and innovation. Mayo Clinic prioritizes this approach through an integrated multispecialty model that aligns disciplines, fosters collaboration, and embeds quality into daily practice. This article explores the fundamental principles that guide health care transformation, including the utilization of diverse quality measures, the development of a comprehensive, enterprise-wide Quality Assurance and Practice Improvement plan, and the implementation of a learning health system. By focusing on structural, process, outcome, and patient experience measures, as well as staff engagement and real-time data monitoring, health care institutions can sustain a culture of safety and achieve high-reliability performance. Additionally, ongoing education, leadership engagement, and the use of innovative tools like e-learning and virtual reality simulations further enhance safety outcomes. Through these initiatives, health care institutions can continually advance their mission to provide world-class health care.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1385-1401"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Causes of Lynch Syndrome: EPCAM Deletion and MSH2 Inversion","authors":"Wei Shen PhD,&nbsp;Lori A. Erickson MD,&nbsp;Sounak Gupta MBBS, PhD","doi":"10.1016/j.mayocp.2025.04.014","DOIUrl":"10.1016/j.mayocp.2025.04.014","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1450-1452"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mayo Clinic Proceedings’ Central Role in the Clinician Well-being Movement","authors":"Tait D. Shanafelt MD","doi":"10.1016/j.mayocp.2025.06.012","DOIUrl":"10.1016/j.mayocp.2025.06.012","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1270-1274"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Foreign Body Ingestions and Food Impactions: Advice for General Practitioners","authors":"Vijayvardhan Kamalumpundi MD ,&nbsp;Bibek Saha MD ,&nbsp;Cadman Leggett MD","doi":"10.1016/j.mayocp.2025.03.035","DOIUrl":"10.1016/j.mayocp.2025.03.035","url":null,"abstract":"<div><div>Foreign body ingestions and esophageal food impactions are common in emergency and general medicine settings. Whereas most cases resolve spontaneously, prompt evaluation and treatment are paramount in preventing morbidity and death. Foreign body ingestion occurs across all age groups, with higher risk in children and certain adult populations. Esophageal food impaction, largely due to obstruction of the esophagus by food boluses, has an estimated annual incidence of 13 per 100,000 person-years. Endoscopy is the preferred intervention for both foreign body ingestion and esophageal food impaction, with imaging aiding in localization, particularly for sharp objects or suspected perforations. Given the strong association of esophageal food impaction with eosinophilic esophagitis, esophagogastroduodenoscopy with biopsy is recommended for these cases, particularly in patients with recurrent impactions.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1411-1419"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rosai-Dorfman Disease","authors":"Qinglin Zhong MD ,&nbsp;Xueqi Sun MD ,&nbsp;Binglin Lai MD","doi":"10.1016/j.mayocp.2025.04.001","DOIUrl":"10.1016/j.mayocp.2025.04.001","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1437-1438"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research in Medical School: Highlighting the Fruit of the Longitudinal Research Experience in the Mayo Clinic Alix School of Medicine","authors":"Elizabeth K. Farkouh MD ,&nbsp;Alexander Krueger MD ,&nbsp;Jessica Weng BS ,&nbsp;Lisa A. Marks MLS ,&nbsp;Hugo E. Vargas MD","doi":"10.1016/j.mayocp.2025.03.031","DOIUrl":"10.1016/j.mayocp.2025.03.031","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1290-1292"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"81-Year-Old Man With Shortness of Breath and Weakness","authors":"Trevor Gauthier MD ,&nbsp;Savannah R. Whitfield DO ,&nbsp;Claire E. Raphael MBBS, PhD","doi":"10.1016/j.mayocp.2024.07.027","DOIUrl":"10.1016/j.mayocp.2024.07.027","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1432-1436"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycohemoglobin Variations and Long-term Risk of Incident Heart Failure in Patients With Type 2 Diabetes","authors":"Fu-Chih Hsiao ,&nbsp;Chia-Pin Lin ,&nbsp;Tzyy-Jer Hsu ,&nbsp;Ying-Chang Tung ,&nbsp;Yi-Hsin Chan ,&nbsp;Shao-Wei Chen ,&nbsp;Pao-Hsien Chu MD","doi":"10.1016/j.mayocp.2024.12.022","DOIUrl":"10.1016/j.mayocp.2024.12.022","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the association between long-term glycohemoglobin variations and the onset of incident heart failure (HF) in individuals with diabetes, addressing the phenotype concerning left ventricular ejection fraction and etiology.</div></div><div><h3>Patients and Methods</h3><div>This retrospective study identified patients with type 2 diabetes from a multicenter database between January 2007 and December 2010 who had multiple hemoglobin A_1c (HbA_1c) measurements during the 4 years after the initial diagnosis of diabetes, calculating variations using average real variability. Patients were followed from the end of run-in period, with HF hospitalization as the primary outcome. Cox proportional hazard models, adjusted for mean HbA_1c and baseline characteristics, were used to evaluate the relationship between HbA_1c variations and outcomes.</div></div><div><h3>Results</h3><div>We identified 53,748 patients with an average of 12.7 HbA_1c measurements. The average follow-up time was 6.2 years, and the cumulative incidence of HF hospitalization was 6.0 per 1000 person-years. Patients with an average visit-to-visit change in HbA_1c exceeding 0.778% were independently associated an elevated risk of hospitalization (HR, 1.28; 95% CI, 1.09 to 1.52). This association persisted regardless of reduced (HR, 1.31; 95% CI, 1.02 to 1.68) or preserved ejection fraction (HR, 1.26; 95% CI, 1.01 to 1.58) and ischemic (HR, 1.30; 95% CI, 1.04 to 1.61) or nonischemic HF (HR, 1.71; 95% CI 1.34 to 2.18).</div></div><div><h3>Conclusion</h3><div>Hemoglobin A_1c variations independently correlated with increased risk of HF hospitalization, encompassing both reduced and preserved ejection fraction, as well as ischemic and nonischemic HF. An average visit-to-visit change in HbA_1c exceeding 0.778% can serve as a simple indicator for the risk of HF in patients with type 2 diabetes.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1332-1344"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Postural Orthostatic Tachycardia Syndrome","authors":"Jay B. Lusk MD, MBA ,&nbsp;Cheryl Kalapura BS ,&nbsp;Fan Li PhD ,&nbsp;Brian Mac Grory MB BCh BAO ,&nbsp;Emily O’Brien PhD ,&nbsp;Shannon Aymes MD, MPH","doi":"10.1016/j.mayocp.2025.04.027","DOIUrl":"10.1016/j.mayocp.2025.04.027","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1442-1445"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}