Mayo Clinic proceedings最新文献

{"title":"Reimagining the Electronic Health Record to Reduce Administrative Burden","authors":"Megna M. Kuverji MHA , Natalie A. Caine MHA , Jon O. Ebbert MD , Vijay H. Shah MD","doi":"10.1016/j.mayocp.2025.04.029","DOIUrl":"10.1016/j.mayocp.2025.04.029","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1293-1296"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General Information","authors":"","doi":"10.1016/S0025-6196(25)00367-2","DOIUrl":"10.1016/S0025-6196(25)00367-2","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Page A7"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Need for Speed: Improving Muscle Power for Longevity","authors":"Salvatore Carbone PhD, MS, RDN, FHFSA, FASPEN, Windy W. Alonso PhD, RN, FHFSA, FAHA","doi":"10.1016/j.mayocp.2025.06.011","DOIUrl":"10.1016/j.mayocp.2025.06.011","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1281-1284"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Renal Function and Acute Kidney Injury on Long-term Outcomes After Percutaneous Coronary Intervention","authors":"Vinayak Nagaraja MD ,&nbsp;Charanjit S. Rihal MD ,&nbsp;Guy Reeder MD ,&nbsp;Karl A. Nath MBChB ,&nbsp;Bradley R. Lewis MS ,&nbsp;Mandeep Singh MD, MPH","doi":"10.1016/j.mayocp.2025.01.020","DOIUrl":"10.1016/j.mayocp.2025.01.020","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the incidence, predictors, and prognostic implications of acute kidney injury (AKI) after percutaneous coronary intervention (PCI).</div></div><div><h3>Patients and Methods</h3><div>Retrospective analysis of the Mayo Clinic PCI registry identified 9199 patients who underwent PCI from January 1, 2009, through June 30, 2023.</div></div><div><h3>Results</h3><div>A total of 856 patients (9.3%) developed AKI (increase in serum creatinine level by ≥0.3 mg/dL or ≥1.5 times baseline), with 87 (0.9%) requiring hemodialysis. A monotonic increase in the yearly incidence of AKI was observed (<em>P</em>&lt;.001). In multivariable analysis, AKI was associated with older age (odds ratio [OR], 1.01; 95% CI, 1.00 to 1.02), female sex (OR, 1.27; 95% CI, 1.08 to 1.49), diabetes (OR, 1.62; 95% CI, 1.38 to 1.89), congestive heart failure (OR, 2.99; 95% CI, 2.54 to 3.52), chronic kidney disease (OR, 2.46; 95% CI, 2.00 to 3.02), acute myocardial infarction (OR, 3.34; 95% CI, 2.80 to 3.99), intra-aortic balloon pump (OR, 3.49; 95% CI, 2.55 to 4.73), and contrast volume (OR, 1.28; 95% CI, 1.17 to 1.41). In-hospital mortality was 11.1% vs 1.0% in patients with vs without AKI (<em>P</em>&lt;.001). After adjustment, AKI remained strongly associated with in-hospital mortality (hazard ratio, 5.75; 95% CI, 4.06 to 8.13). Among hospital survivors, 1-, 5-, and 10-year all-cause mortality, repeated revascularization, myocardial infarction, and major adverse cardiovascular event rates were significantly higher in those who developed AKI.</div></div><div><h3>Conclusions</h3><div>The incidence of AKI after PCI remains high in the contemporary era. Higher in-hospital and long-term mortality and adverse cardiac event rates were noted in patients who developed AKI after PCI.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1309-1318"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Outcomes of Patients With Cholangiocarcinoma and Primary Sclerosing Cholangitis","authors":"Srija Manchkanti MD ,&nbsp;Udhayvir Singh Grewal MD","doi":"10.1016/j.mayocp.2025.04.013","DOIUrl":"10.1016/j.mayocp.2025.04.013","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1439-1441"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independent and Joint Associations of Obesity and Hypertension on Incident Heart Failure: A Pooled Cohort Analysis","authors":"Arsalan Hamid MD ,&nbsp;Abdul Mannan Khan Minhas MD, MS ,&nbsp;Affan M. Rizwan ,&nbsp;Daisuke Kamimura MD, PhD ,&nbsp;Maria Clarissa Tio MD, MS ,&nbsp;Candace Howard Claudio MD, PhD ,&nbsp;Ambarish Pandey MD, MS ,&nbsp;Robert Mentz MD ,&nbsp;Vijay Nambi MD, PhD ,&nbsp;Daniel W. Jones MD ,&nbsp;John E. Hall PhD ,&nbsp;Javed Butler MD, MPH, MBA ,&nbsp;Michael E. Hall MD, MS","doi":"10.1016/j.mayocp.2025.01.025","DOIUrl":"10.1016/j.mayocp.2025.01.025","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the independent and combined associations of obesity and hypertension on incident heart failure (HF).</div></div><div><h3>Methods</h3><div>We studied participants of 3 epidemiologic cohorts: Atherosclerosis Risk in Communities (baseline visit 4, 1996-1998, to follow-up, 2017), Multi-Ethnic Study of Atherosclerosis (baseline examination 1, 2000-2002, to follow-up, 2015), and Jackson Heart Study (baseline visit 1, 2000-2004, to follow-up, 2014). Participants were stratified into 4 groups: neither obesity nor hypertension (reference), only obesity, only hypertension, or both. Hypertension was defined as systolic blood pressure of 140 mm Hg or higher, diastolic blood pressure of 90 mm Hg or higher, or use of antihypertensive medications at baseline. Obesity was defined as body mass index of 30 kg/m² or higher. Cox proportional hazards models adjusted for prespecified covariates were used to assess the association of the 4 groups with incident HF.</div></div><div><h3>Results</h3><div>Overall, 18,351 participants were included in the analyses. Participants with only obesity (adjusted hazard ratio [aHR], 1.60; 95% CI, 1.36 to 1.88) and only hypertension (aHR, 2.10; 95% CI, 1.87 to 2.37) demonstrated a higher risk of incident HF, whereas the highest risk of incident HF was in participants with both comorbidities (aHR, 2.97; 95% CI, 2.63 to 3.36) compared with participants with neither. Furthermore, participants with both obesity and hypertension had a higher risk of incident HF (aHR, 1.86; 95% CI, 1.60 to 2.16) compared with only obesity.</div></div><div><h3>Conclusion</h3><div>Obesity and hypertension are associated with incident HF, and individuals with both have the highest risk of HF. Hypertension increases the risk of incident HF in participants with obesity. These data highlight the impact of obesity and hypertension and how together they have a higher risk of HF.</div></div>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1297-1308"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining Risk and Predicting Disease—Limelight, August 2025","authors":"Karl A. Nath MBChB (Editor-in-Chief)","doi":"10.1016/j.mayocp.2025.06.018","DOIUrl":"10.1016/j.mayocp.2025.06.018","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1267-1269"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Reply: Health Inequalities of Early-Onset Gastrointestinal Cancers From 2000 to 2021: Findings Based on the Global Burden of Disease Study 2021","authors":"Pojsakorn Danpanichkul MD,&nbsp;Krittameth Rakwong,&nbsp;Mazen Noureddin MD,&nbsp;Donghee Kim MD,&nbsp;Denise M. Harnois DO,&nbsp;Ju Dong Yang MD,&nbsp;Michael B. Wallace MD,&nbsp;Karn Wijarnpreecha MD","doi":"10.1016/j.mayocp.2025.04.018","DOIUrl":"10.1016/j.mayocp.2025.04.018","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1447-1449"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons From a Contemporary Cohort: Acute Kidney Injury After Percutaneous Coronary Intervention and the Need for Renewed Prevention Strategies","authors":"Setor K. Kunutsor MD, PhD,&nbsp;Jari A. Laukkanen MD, PhD","doi":"10.1016/j.mayocp.2025.05.006","DOIUrl":"10.1016/j.mayocp.2025.05.006","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1278-1280"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Inequalities of Early-Onset Gastrointestinal Cancers From 2000 to 2021: Findings Based on the Global Burden of Disease Study 2021","authors":"Xinying Shen,&nbsp;Yunqian Zhang,&nbsp;Jun Qiao PhD","doi":"10.1016/j.mayocp.2025.04.017","DOIUrl":"10.1016/j.mayocp.2025.04.017","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 8","pages":"Pages 1446-1447"},"PeriodicalIF":6.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}