Mayo Clinic proceedings最新文献_第2页

66-Year-Old Woman With Chronic Diarrhea. 66岁女性慢性腹泻。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-04 DOI: 10.1016/j.mayocp.2024.03.007

Alexandra Allman, Joelle N Friesen, Sahil Khanna

引用次数: 0

PREVENT and Pooled Cohort Equations in Atherosclerotic Cardiovascular Disease Risk Prediction: A Post Hoc Analysis of SPRINT. 预防和合并队列方程在动脉粥样硬化性心血管疾病风险预测中的应用：SPRINT的事后分析

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-04 DOI: 10.1016/j.mayocp.2024.08.024

Naman S Shetty, Mokshad Gaonkar, Nirav Patel, Nehal Vekariya, Peng Li, Garima Arora, Pankaj Arora

引用次数: 0

Peristomal Ecthyma Gangrenosum. 坏疽性坏疽。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-03 DOI: 10.1016/j.mayocp.2024.11.004

Frank Z Jing, Afsaneh Alavi, Jenny L Link

引用次数: 0

51-Year-Old Woman With Bilateral Facial Palsy and Lower Extremity Weakness. 51岁女性，双侧面瘫伴下肢无力。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-03 DOI: 10.1016/j.mayocp.2024.03.006

David O Sohutskay, Jacob D Goodwin, Kelsey M Smith

引用次数: 0

Difficult Encounters in Chronic Pain Patients: A Cohort Study. 慢性疼痛患者的困难遭遇：一项队列研究。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI: 10.1016/j.mayocp.2024.08.010

Steven P Cohen, Winnie L Liu, Tina L Doshi, Eric J Wang, Evelien van Gelderen, Resham Mawalkar, Eellan Sivanesan, Kayode A Williams, Paul J Christo, Shravani Durbhakula, Glenn Treisman, Annie Hsu

{"title":"Difficult Encounters in Chronic Pain Patients: A Cohort Study.","authors":"Steven P Cohen, Winnie L Liu, Tina L Doshi, Eric J Wang, Evelien van Gelderen, Resham Mawalkar, Eellan Sivanesan, Kayode A Williams, Paul J Christo, Shravani Durbhakula, Glenn Treisman, Annie Hsu","doi":"10.1016/j.mayocp.2024.08.010","DOIUrl":"10.1016/j.mayocp.2024.08.010","url":null,"abstract":"Objective: To determine variables associated with difficult clinical encounters.Patients and methods: This was a cross-sectional study of 428 new patients evaluated from 2022 to 2023. Demographic, clinical, social (eg, missed appointments, prior felony conviction, prior pain physicians, medical assistance) and visit-related (eg, visit took longer than expected, difficulty communicating) information was recorded, supplemented by in-person history gathered by the trainee and attending whose demographic data were also recorded. Physicians independently rated the \"difficulty\" of the encounter on a 6-point Likert scale from 1 = very easy/pleasant, 2 = easy/pleasant, 3 = neutral/average, 4 = difficult, 5 = very difficult, to 6 = extremely difficult. A difficult encounter was a combined trainee and attending rating of one IQR above the median of 2.0±1.75.Results: Among 428 participants, mean ± SD age was 54.2±15.8 years and 261 (61.0%) were female. Attending gender, gender concordance, race and racial concordance, and years of physician experience were not associated with difficulty. In multivariable analysis, requesting opioids (P=.001), lengthier than expected visit (P<.001), hostile/demanding behavior (P=.003), refusal to try recommended treatment (P=.002), unrealistic expectations (P<0.001), and difficulty communicating (P=.02) were associated with difficult encounters.Conclusion: Most variables associated with physician impressions of difficult encounters were visit-related, suggesting some patient-related factors (eg, prior substance abuse, translator requirement) may be less relevant in pain patients. Future research should evaluate interventions designed to decrease the difficulty of encounters and determine their effect on patients and physicians.","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":"30-41"},"PeriodicalIF":6.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The "Dear Doctor" Postcards of the 1950s and 1960s: An Advertising Method With A Global Philatelic Flair. 20世纪五六十年代的“亲爱的医生”明信片：一种具有全球集邮风格的广告方法。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 DOI: 10.1016/j.mayocp.2024.11.017

David P Steensma

引用次数: 0

Factors Associated With Enrollment to a Decentralized Study. 与入组分散研究相关的因素。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI: 10.1016/j.mayocp.2024.03.022

Adil E Bharucha, Michelle L Bublitz, Robert A Vierkant, Tony C Luehrs, Karen A Konzen, David A Weiss, Tony A Hart, Christine M Boos, Alina M Allen, Kent R Bailey, Konstantinos N Lazaridis

{"title":"Factors Associated With Enrollment to a Decentralized Study.","authors":"Adil E Bharucha, Michelle L Bublitz, Robert A Vierkant, Tony C Luehrs, Karen A Konzen, David A Weiss, Tony A Hart, Christine M Boos, Alina M Allen, Kent R Bailey, Konstantinos N Lazaridis","doi":"10.1016/j.mayocp.2024.03.022","DOIUrl":"10.1016/j.mayocp.2024.03.022","url":null,"abstract":"Objective: To assess whether the mode and formatting of invitations affect enrollment in a large, decentralized study.Patients and methods: Between July 1, 2022, and October 30, 2022, we prospectively compared various approaches to enroll patients in the Tapestry DNA Sequencing Research Study, a decentralized exome-sequencing study. In phase 1, patients were randomized to receive invitations via the electronic health record (EHR) patient portal or email (cohort 1, 69,852 patients). Phase 2 randomized in a 2×2 factorial design to receive (by portal or email) standard or enhanced (ie, more visually appealing) invitations (cohort 2, 26,198 patients). Factors that predicted enrollment rates were analyzed.Results: The enrollment rate was greater in cohort 2 (1,785 of 24,550, 7.27%) than 1 (1,758 or 69,765, 2.52%) and remained significant after multivariable adjustment (odds ratio, 1.31; 95% CI, 1.19-1.45). Enrollment rates were greater in women than men, patients 50 to 70 years of age than younger patients, White or non-Hispanic or Latino patients than those in other racial categories, urban than rural residents, and patients who had more health care encounters or more recent health care before this study (P<.02). The enrollment rate was also greater when invitations were delivered via EHR than email (odds ratio, 1.56; 95% CI, 1.44-1.68; P<.001).Conclusion: Invitations via EHR rather than email facilitate enrollment to large, decentralized studies. Enhanced display of invitation material did not increase enrollment. Lower enrollment rates in men, younger individuals, non-White and Hispanic individuals, and rural residents highlight a continued need to focus enrollment strategies on these subgroups.","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":"52-67"},"PeriodicalIF":6.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long Dosing Intervals of Parenteral Antiosteoporosis Medications and the Decrease in Societal Fracture Risk: An 11-Year Nationwide Population-Based Cohort Study. 长剂量间隔的肠外抗骨质疏松药物与社会骨折风险的降低：一项为期11年的全国性人群队列研究

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 Epub Date: 2024-12-12 DOI: 10.1016/j.mayocp.2024.05.002

Shau-Huai Fu, Hung-Kuan Yen, Rong-Sen Yang, Chih-Chien Hung, Jou-Wei Lin, Ming-Tsung Lee, Ho-Min Chen, Chih-Hsing Wu, Chih-Cheng Hsu, Chung-Yi Li, Olivier Q Groot, Chen-Yu Wang

{"title":"Long Dosing Intervals of Parenteral Antiosteoporosis Medications and the Decrease in Societal Fracture Risk: An 11-Year Nationwide Population-Based Cohort Study.","authors":"Shau-Huai Fu, Hung-Kuan Yen, Rong-Sen Yang, Chih-Chien Hung, Jou-Wei Lin, Ming-Tsung Lee, Ho-Min Chen, Chih-Hsing Wu, Chih-Cheng Hsu, Chung-Yi Li, Olivier Q Groot, Chen-Yu Wang","doi":"10.1016/j.mayocp.2024.05.002","DOIUrl":"10.1016/j.mayocp.2024.05.002","url":null,"abstract":"Objective: To evaluate the relationship between different dosing intervals of antiosteoporosis medications (AOMs) and the subsequent fracture risk among patients with newly initiated AOM therapies.Patients and methods: In a nationwide population-based cohort study based on Taiwan's National Health Insurance Research Database, osteoporosis patients with 50 years of age or older who newly initiated AOM from January 1, 2008, to December 31, 2018 (n=336,229) were included. We categorized AOMs into short dosing intervals (oral AOMs) or long dosing intervals (parenteral AOMs). The adherence of treatment by medication possession ratio and subsequent fracture after treatment for 3 years were measured.Results: Among patients who initiated parenteral AOMs, the percentage of patients with high adherence (medication possession ratio ≥75%) increased from 33% in 2008 to 69% in 2018. However, among patients who initiated oral AOMs, the percentage of high adherence remained stable (30%) between 2008 and 2018. The use of parenteral AOMs increased from 1% in 2008 to 62% in 2018. At the same time, the percentage of high adherence of those initiated AOMs significantly increased from 34% in 2008 to 61% in 2018. The risk of subsequent fracture decreased significantly between 2008 and 2018 after controlling for all potential confounders (HR, 0.85; 95% CI, 0.81 to 0.89).Conclusion: AOMs with long dosing intervals not only increased adherence but also associated with the decrease in subsequent fracture risk at a nationwide scale.","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":"68-79"},"PeriodicalIF":6.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mayo Clinic Proceedings: Commemorating a Century of Continuous Communication. 梅奥诊所学报：纪念一个世纪的持续交流。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 DOI: 10.1016/j.mayocp.2024.11.014

Karl A Nath, Morna Conway, Rafael Fonseca

引用次数: 0

Eculizumab Improves Renal Survival in Complement-Mediated TMA Secondary to SLE. Eculizumab改善补体介导的SLE继发TMA患者的肾脏生存。

IF 6.9 2区医学

Mayo Clinic proceedings Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI: 10.1016/j.mayocp.2024.10.001

Yakai Fu, Zhiwei Chen, Jie Chen, Fangfang Sun, Ting Li, Nan Shen, Xiaodong Wang, Shuang Ye

引用次数: 0