Mayo Clinic proceedings最新文献

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Long-term Outcomes of Hypertension and Antihypertensive Drugs in Healthy Young Adults: A Nationwide Population-Based Prospective Cohort Study in Korea. 健康年轻人高血压和抗高血压药物的长期预后:韩国一项基于全国人群的前瞻性队列研究
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-02 DOI: 10.1016/j.mayocp.2025.03.016
In Tae Moon, Yung Ki Park, Hyeong-Joong Yi, Hyoung-Joon Chun, Kyu-Sun Choi, Young-Jun Lee, Hyun Young Kim
{"title":"Long-term Outcomes of Hypertension and Antihypertensive Drugs in Healthy Young Adults: A Nationwide Population-Based Prospective Cohort Study in Korea.","authors":"In Tae Moon, Yung Ki Park, Hyeong-Joong Yi, Hyoung-Joon Chun, Kyu-Sun Choi, Young-Jun Lee, Hyun Young Kim","doi":"10.1016/j.mayocp.2025.03.016","DOIUrl":"10.1016/j.mayocp.2025.03.016","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effect of hypertension (HTN) and antihypertensive medications on the incidence of cardiovascular disease in healthy young adults (approximately 20 to 45 years).</p><p><strong>Patients and methods: </strong>In total, 4,590,597 young Korean adults without comorbidities who underwent regular health examinations were included in this study. They were stratified into 4 groups according to their blood pressure (BP) (optimal BP, normal BP, high normal BP, and HTN). The primary outcome was a composite of the incidence of myocardial infarction and ischemic and hemorrhagic stroke, obtained by tracking the medical use data of the first-ever International Classification of Diseases, Tenth Revision codes. Subgroup analysis was conducted by categorizing the HTN group into 2 subgroups according to the prescription ratios of the antihypertensive drugs during the follow-up period.</p><p><strong>Results: </strong>The average age was 33.8 years, and the median follow-up duration was 15.9 years. Hypertension elevated the incidence risk of major cardiovascular disease by 2.16 times compared with that of the optimal BP group. Dyslipidemia and HTN were the most dominant risk factors for myocardial infarction and stroke, respectively. In the subgroup analysis, antihypertensive medications decreased the incidence of cardiovascular disease by 70% in all diseases.</p><p><strong>Conclusion: </strong>Cardiovascular risk factors, including HTN, contribute to major cardiovascular disease incidence in young adults. Antihypertensive medications decreased the major cardiovascular disease incidence estimates.</p>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Early Career Phase: Fostering Physician Well-being Over the Career Life Cycle. 早期职业阶段:在职业生命周期中培养医生的幸福感。
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-02 DOI: 10.1016/j.mayocp.2025.05.025
Lisa Rotenstein, Elizabeth Harry, Tait Shanafelt
{"title":"The Early Career Phase: Fostering Physician Well-being Over the Career Life Cycle.","authors":"Lisa Rotenstein, Elizabeth Harry, Tait Shanafelt","doi":"10.1016/j.mayocp.2025.05.025","DOIUrl":"10.1016/j.mayocp.2025.05.025","url":null,"abstract":"<p><p>This article is the second chapter in a series of 5 articles considering the different stages of physicians' career life cycle. The present article focuses on exploring the early career phase. The early career phase represents an exciting time when physicians establish themselves in independent practice and develop their professional identity. Despite the excitement and opportunity of this phase, it is marked by several challenges, including those related to navigating new practice settings, defining and integrating one's personal and professional priorities, and developing a long-term approach to a physician career. Organizations can support physicians' effective navigation of the early career phase in multiple ways, ranging from the provision of individual supports such as mentorship and coaching to enhancing care processes and provision of standard supports for supporting work-life integration. Ultimately, organizations have a unique opportunity to bring early career physicians into the fold as satisfied colleagues and ensure they are set on the path to long and fulfilling careers.</p>","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrophysiologic and Anatomic Changes in Patients With oHCM on Mavacamten: 1-Year Insights From AI-ECG and Echocardiography Data. 马伐卡坦治疗oHCM患者的电生理和解剖变化:来自AI-ECG和超声心动图数据的1年见解。
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-02 DOI: 10.1016/j.mayocp.2025.07.006
Mustafa Suppah, Humam Abo Abdullah, Amro Badr, Kaitlin Roehl, Reza Arsanjani, Dan Sorajja, Jeffrey B Geske, Said Alsidawi
{"title":"Electrophysiologic and Anatomic Changes in Patients With oHCM on Mavacamten: 1-Year Insights From AI-ECG and Echocardiography Data.","authors":"Mustafa Suppah, Humam Abo Abdullah, Amro Badr, Kaitlin Roehl, Reza Arsanjani, Dan Sorajja, Jeffrey B Geske, Said Alsidawi","doi":"10.1016/j.mayocp.2025.07.006","DOIUrl":"10.1016/j.mayocp.2025.07.006","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mayo Clinic Proceedings in the Last Century: Seminal Contributions by Mayo Clinic Physicians and Researchers to the Field of Neurogastroenterology 梅奥诊所在上个世纪的会议记录:梅奥诊所医生和研究人员对神经胃肠病学领域的开创性贡献
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2025.07.012
Michael Camilleri MD, DSc, Nicholas J. Talley AC, MD, PhD
{"title":"Mayo Clinic Proceedings in the Last Century: Seminal Contributions by Mayo Clinic Physicians and Researchers to the Field of Neurogastroenterology","authors":"Michael Camilleri MD, DSc,&nbsp;Nicholas J. Talley AC, MD, PhD","doi":"10.1016/j.mayocp.2025.07.012","DOIUrl":"10.1016/j.mayocp.2025.07.012","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1458-1462"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Myeloid Leukemia With Mutated NPM1 Mimicking Acute Promyelocytic Leukemia 急性髓系白血病与突变的NPM1模拟急性早幼粒细胞白血病。
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2025.04.004
Husam A. Jum’ah MBBS, Jennifer L. Herrick MD
{"title":"Acute Myeloid Leukemia With Mutated NPM1 Mimicking Acute Promyelocytic Leukemia","authors":"Husam A. Jum’ah MBBS,&nbsp;Jennifer L. Herrick MD","doi":"10.1016/j.mayocp.2025.04.004","DOIUrl":"10.1016/j.mayocp.2025.04.004","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1575-1577"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General Information 一般信息
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/S0025-6196(25)00436-7
{"title":"General Information","authors":"","doi":"10.1016/S0025-6196(25)00436-7","DOIUrl":"10.1016/S0025-6196(25)00436-7","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Page A7"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Older Populations: The Impact of Smoking and Diet and the Prevalence of Polypharmacy—Limelight, September 2025 老年人口:吸烟和饮食的影响以及多种药物的流行- limelight, 2025年9月
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2025.07.026
Karl A. Nath MBChB (Editor-in-Chief)
{"title":"Older Populations: The Impact of Smoking and Diet and the Prevalence of Polypharmacy—Limelight, September 2025","authors":"Karl A. Nath MBChB (Editor-in-Chief)","doi":"10.1016/j.mayocp.2025.07.026","DOIUrl":"10.1016/j.mayocp.2025.07.026","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1455-1457"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
45-Year-Old Woman With Transient Loss of Consciousness and Fall 45岁女性短暂失去意识并摔倒。
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2024.08.030
Ryan T.D. Nguyen MD, MEng , Daniel Sykora MD , Benjamin R. Stultz MD
{"title":"45-Year-Old Woman With Transient Loss of Consciousness and Fall","authors":"Ryan T.D. Nguyen MD, MEng ,&nbsp;Daniel Sykora MD ,&nbsp;Benjamin R. Stultz MD","doi":"10.1016/j.mayocp.2024.08.030","DOIUrl":"10.1016/j.mayocp.2024.08.030","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1643-1648"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Myeloperoxidase Inhibition: The Search for HFpEF Therapies Continues 急性髓过氧化物酶抑制:HFpEF疗法的研究仍在继续
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2025.07.017
Navin Suthahar MD, MSc, PhD, FESC
{"title":"Acute Myeloperoxidase Inhibition: The Search for HFpEF Therapies Continues","authors":"Navin Suthahar MD, MSc, PhD, FESC","doi":"10.1016/j.mayocp.2025.07.017","DOIUrl":"10.1016/j.mayocp.2025.07.017","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1465-1467"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Ewing Sarcoma of the Kidney 原发性肾尤文氏肉瘤
IF 6.7 2区 医学
Mayo Clinic proceedings Pub Date : 2025-09-01 DOI: 10.1016/j.mayocp.2025.06.015
Ahmed Abdelfattah MB, BCh, BAO, Burak Tekin MD, Lori A. Erickson MD
{"title":"Primary Ewing Sarcoma of the Kidney","authors":"Ahmed Abdelfattah MB, BCh, BAO,&nbsp;Burak Tekin MD,&nbsp;Lori A. Erickson MD","doi":"10.1016/j.mayocp.2025.06.015","DOIUrl":"10.1016/j.mayocp.2025.06.015","url":null,"abstract":"","PeriodicalId":18334,"journal":{"name":"Mayo Clinic proceedings","volume":"100 9","pages":"Pages 1673-1674"},"PeriodicalIF":6.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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