Aspirantskiy Vestnik Povolzhiya最新文献

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Talc retinopathy as a result of long-term intravenous drug abuse 滑石粉视网膜病变是长期静脉注射药物滥用的结果
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.4-7
A. D. Matyaeva, Kseniya I. Slastina
{"title":"Talc retinopathy as a result of long-term intravenous drug abuse","authors":"A. D. Matyaeva, Kseniya I. Slastina","doi":"10.55531/2072-2354.2023.23.2.4-7","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.4-7","url":null,"abstract":"Narcotic substances have a pronounced toxic effect on the entire body and can lead to disability. Despite ongoing efforts to combat drug addiction, in today's society, many drugs are available for potential use. Their destructive action leads to numerous adverse ocular and systemic manifestations. The most frequently, the drug-users are people of working age, in whom visual impairment leads to restrictions on labor and social activities. \u0000The article considers a clinical case of talcum retinopathy, which developed as a result of long-term abuse of intravenous drugs; the ophthalmic manifestations and a possible treatment option are described.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132401730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacotherapy of epilepsy: new solutions to old problems 癫痫的药物治疗:老问题的新解决方案
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.43-52
Anton S. Romanov, E. F. Sharahova
{"title":"Pharmacotherapy of epilepsy: new solutions to old problems","authors":"Anton S. Romanov, E. F. Sharahova","doi":"10.55531/2072-2354.2023.23.2.43-52","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.43-52","url":null,"abstract":"The literature review provides an update on recent advances in antiepileptic pharmacotherapy. The article considers the mechanisms of action of the drugs, the range of efficacy, side effects and enzyme-inducing properties, potential teratogenicity. \u0000A review of the literature revealed some of the problems of patients with epilepsy remaining unresolved to this day. Despite an increase in the number of anticonvulsants in recent years, one-third of patients are pharmacoresistant to antiepileptic therapy and continue to suffer from seizures. The hope for reducing the proportion of patients with uncontrolled seizures rests on future therapeutic developments, including targeted therapies aimed at the molecular mechanisms underlying the epilepsy pathogenesis. Clinical outcomes in patients with epilepsy could also significantly improve with advances in the development of new highly accurate diagnostic and treatment methods, the identification of biomarkers for drug development, as well as routine clinical follow-up and the introduction of truly innovative disease-modifying therapies.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124024939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Planning the approach in mini percutaneous nephrolithotripsy according to individual kidney anatomy detected by computed tomography 根据计算机断层检查的个体肾脏解剖结构,规划微型经皮肾镜碎石入路
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.37-42
M.Yu. Murushidi, R. S. Nizamova, A. Kolsanov, Ramilya D. Andreeva, O. Zhurkina, T. Gavrilova
{"title":"Planning the approach in mini percutaneous nephrolithotripsy according to individual kidney anatomy detected by computed tomography","authors":"M.Yu. Murushidi, R. S. Nizamova, A. Kolsanov, Ramilya D. Andreeva, O. Zhurkina, T. Gavrilova","doi":"10.55531/2072-2354.2023.23.2.37-42","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.37-42","url":null,"abstract":"Aim to analyze postoperative complications after mini percutaneous nephrolithotripsy, taking into account an assessment of individual variations of kidney anatomy. \u0000Material and methods. Postoperative complications after mini percutaneous nephrolithotripsy were analyzed in 60 patients who underwent preoperative CT urography with intravenous bolus contrast and 3D reconstruction. \u0000Results. We found no significant correlation between the number of complications after mini percutaneous nephrolithotripsy and the type of division of the branches of the renal artery of the 2nd order, as well as no dependence of the occurrence of complications on the presence of accessory arteries. A moderate correlation between the number of complications and the number of accesses was noted. \u0000Conclusion. In mini percutaneous nephrolithotripsy, the preoperative planning and marking of the access trajectory can significantly reduce the number of postoperative complications.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"56 28","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120888927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of UV spectrophotometry and reversed-phase HPLC to determine the ionization constant of a new biologically active compound 应用紫外分光光度法和反相高效液相色谱法测定一种新的生物活性化合物的电离常数
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.60-65
Arthur T. Tsecheev, Yurii N. Karpenko
{"title":"Application of UV spectrophotometry and reversed-phase HPLC to determine the ionization constant of a new biologically active compound","authors":"Arthur T. Tsecheev, Yurii N. Karpenko","doi":"10.55531/2072-2354.2023.23.2.60-65","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.60-65","url":null,"abstract":"Aim to determine the ionization constant (pKa) of the biologically active compound 2-ABPPC by UV spectrophotometry and high performance liquid chromatography (HPLC). \u0000Material and methods. The object of the study was the substance 2-ABPPC (2-amino-1-(4-bromophenyl)-5-(3,3-dimethyl-2-oxobutylidene)-4-oxo-4,5-dihydro-1H-pyrrole-3- carboxamide). The methods of UV spectrophotometry and high performance liquid chromatography were used to determine the ionization constant. The spectrophotometric analysis was carried out on a Shimadzu UV-1800 spectrophotometer. The chromatographic determination of the pKa value was carried out on an LC-20 Prominence liquid chromatograph (Shimadzu) using a Zorbax Extend-C18 reversed-phase column. \u0000Results. In the course of study, it was found that 2-ABPPC has one pKa value. When using two different methods to estimate the ionization constant, the comparable results were obtained: 7.64 (UV spectrophotometry method) and 7.40 (reversed phase HPLC method).","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124589897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral variability of linear parameters of the kidneys in the normal condition and urolithiasis 肾脏线性参数的双侧变异在正常情况下和尿石症
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.32-36
A. Kolsanov, R. S. Nizamova, M.Yu. Murushidi, Ramilya D. Andreeva, O. Zhurkina, T. Gavrilova
{"title":"Bilateral variability of linear parameters of the kidneys in the normal condition and urolithiasis","authors":"A. Kolsanov, R. S. Nizamova, M.Yu. Murushidi, Ramilya D. Andreeva, O. Zhurkina, T. Gavrilova","doi":"10.55531/2072-2354.2023.23.2.32-36","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.32-36","url":null,"abstract":"Aim to study the linear dimensions of the right and left kidneys in patients with urolithiasis and in individuals without kidney disease. \u0000Material and methods. We assessed the average values of length, thickness and width at the level of the poles and hilum of the kidney in urolithiasis (main group 65 patients) and in the control group (87 healthy people) using the method of 3D reconstruction of the computed tomography data and the method of variational-statistical analysis. \u0000Results. The linear dimensions of the kidneys: length, thickness, width at all levels were larger in the main group than in the control group, due to the expansion of the pyelocaliceal system, as well as edema and, as a result, an increase in the size of the parenchyma in patients with urolithiasis.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132486176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Experimental evaluation of the galvanophoretic dentin nanoimpregnation for recurrent caries prevention 电泳牙本质纳米浸渍预防复发性龋齿的实验评价
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.13-18
A. R. Bessudnova, Vitalii A. Rumyantsev, Georgii A. Frolov, A. Blinova, Vladimir V. Bityukov
{"title":"Experimental evaluation of the galvanophoretic dentin nanoimpregnation for recurrent caries prevention","authors":"A. R. Bessudnova, Vitalii A. Rumyantsev, Georgii A. Frolov, A. Blinova, Vladimir V. Bityukov","doi":"10.55531/2072-2354.2023.23.2.13-18","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.13-18","url":null,"abstract":"Aim to study the dentine galvanophoretic impregnation with nanoparticles of coppercalcium hydroxide (CCH) in the teeth with carious cavities. \u0000Material and methods. The study was conducted on 21 teeth removed for various medical indications, with a concomitant diagnosis \"dental caries\". After mechanical treatment, the cavities were washed with saline solution, then CCH paste was placed on the cavity floor, covered with aluminum foil, drained and isolated with temporary fillings. To maintain the osmotic balance, the teeth were placed in a laboratory model: a plastic bath with saline solution and a melamine sponge, for a period of 1, 14 and 30 days. Then the longitudinal teeth sections were prepared for the electron microscopic examination. \u0000Results. During the CCH galvanophoresis, the dentine impregnation with copper nanoparticles in the area of cavity floor occurred already during the first day of the procedure. The penetration depth reached 10.1 microns. The maximum depth of penetration of particles into the dentin (up to 30 microns) was detected after the 30-days-galvanophoresis. The maximum values of the diffusion coefficient and its velocity were recorded after the first day. With an increase in the time of galvanophoresis to 14 and 30 days, these indicators decreased. \u0000Conclusion. The described method may be used as an option of choice for the prevention of recurrent dental caries, especially in the presence of deep cavities.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126550979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An approach to standardization of licorice herb (glycyrrhiza glabra l.) 甘草药材标准化的探讨
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.53-59
O. Belova, V. Kurkin, E. A. Smirnova, Maksim V. Egorov
{"title":"An approach to standardization of licorice herb (glycyrrhiza glabra l.)","authors":"O. Belova, V. Kurkin, E. A. Smirnova, Maksim V. Egorov","doi":"10.55531/2072-2354.2023.23.2.53-59","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.53-59","url":null,"abstract":"Aim to develop a method for standardization of licorice herb. \u0000Material and methods. The material for the study was licorice herb harvested in Alekseevka settlement of the Samara Region (2021), Tatarskaya Kargala village of Sakmarskiy area of the Orenburg Region (2017), Derzhavinsk city of the Republic of Kazakhstan (2018), Bol'shaya Chernigovka village of Bol'shchernigovsk area of the Samara Region (2019), and a commercial sample of licorice root raw material from AO \"Krasnogorskleksredstva\". In addition, the reference standards (RS) were used: pinostrobin, licuraside, quercetin, rutin, luteolin and glycyram. The authenticity was determined by the thin layer chromatography (qualitative analysis). For the quantitative analysis, we used the differential spectrophotometry, conducted in accordance with Pharmacopoeial monograph 1.2.1.1.0003.15 \"Spectrophotometry in ultraviolet and visible spectra\". The spectral characteristics of water-alcohol extracts were evaluated on spectrophotometer \"Specord 40\" (Analytik Jena AG, Germany). \u0000Results. The dominant flavonoid substance, pinocembrin, was detected. This compound in chloroform-ethanol (4:1) solvent system had blue fluorescence at 365 nm. During the development of the chromatogram with an alkaline solution of diazobenzene sulphonic acid, a light green stain (pinoсembrin) was detected practically at the level of the pinostrobin stain. It is reasonable to determine the diagnostic flavonoid pinocembrin of licorice herb using pinostrobin as the reference standard. The flavonoids pinocembrin and pinostrobin have similar spectral characteristics and are similar in chemical structure. A method has been developed for quantitative determination of the total flavonoids in terms of pinocembrin in water-ethanol extract of licorice herb (Glycyrrhiza glabra L.) using the differential spectrophotometry. The total flavonoid content in the licorice herb varies from 0.390.002% to 3.480.015% (in terms of pinocembrin).","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132748256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative assessment of the occurrence of hyperesthesia after a course of home teeth whitening with various kits 用各种牙套进行家庭牙齿美白疗程后感觉过敏的比较评估
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.27-31
M. Postnikov, O. A. Magsumova, S. Chigarina, M. Korchagina, Viktoriya A. Polkanova
{"title":"A comparative assessment of the occurrence of hyperesthesia after a course of home teeth whitening with various kits","authors":"M. Postnikov, O. A. Magsumova, S. Chigarina, M. Korchagina, Viktoriya A. Polkanova","doi":"10.55531/2072-2354.2023.23.2.27-31","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.27-31","url":null,"abstract":"Aim to assess the sensitivity of hard dental tissues after home teeth whitening with various kits. \u0000Material and methods. The study involved 45 people aged from 20 to 35 years with enamel color A3 and darker on the Vita Classical scale arranged in chromatic order. Using the random sampling method, all patients were divided into 3 groups, 15 people in each group. The course of home whitening lasted for 14 days with the following administration of a course of remineralization therapy for 2 weeks. The presence of hypersensitivity was evaluated before the course of home teeth whitening, after 3 days, 7 days, 2 weeks and 1 month. \u0000Results. The study revealed the highest incidence of hyperesthesia during home teeth whitening in patients of the first group, who used a hydrogen peroxide content of 10%. Presumably, the high percentage of the occurrence of dental hyperesthesia of 2nd degree in patients of this group resulted from the use of hydrogen peroxide as a whitening component, which is a more aggressive agent, if compared to carbamide peroxide. \u0000Conclusion. Home teeth whitening using a system containing 22% carbamide peroxide eliminates the risk of tooth hyperesthesia, since the whitening gel is used in individual trays, carbamide peroxide is used as a whitening agent, and the introduction of amorphous calcium phosphate into the gel does not cause fluid movement in dentinal tubules, thereby not causing sensitivity of the hard tissues of the teeth.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133940344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acrysof IQ Vivity (Alcon) extended depth-of-focus intraocular lens: implantation experience Acrysof IQ Vivity(爱尔康)扩展焦深人工晶状体:植入经验
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-06-16 DOI: 10.55531/2072-2354.2023.23.2.8-12
L. M. Nizamudinova, V. S. Stebnev, S. D. Stebnev, I. Malov
{"title":"Acrysof IQ Vivity (Alcon) extended depth-of-focus intraocular lens: implantation experience","authors":"L. M. Nizamudinova, V. S. Stebnev, S. D. Stebnev, I. Malov","doi":"10.55531/2072-2354.2023.23.2.8-12","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.8-12","url":null,"abstract":"Aim to evaluate the results of the AcrySof IQ Vivity (Alcon) extended-focus intraocular lens implantation in cataract surgery with regard to visual acuity at three distances, independence from glasses, severity of photopic phenomena, and patient satisfaction. \u0000Material and methods. 20 patients (20 eyes) with cataract were examined and operated. All patients underwent phacoemulsification with implantation of IOL with extended focus depth AcrySof IQ Vivity, with the following analysis of treatment results. The follow-up period lasted for 6 months. \u0000Results. In 6 months after surgery, the uncorrected far distance visual acuity was 0.880.04, the middle distance acuity 0.770.01, the near distance acuity 0.610.05. The maximum corrected far distance visual acuity was 0.930.06, the middle distance acuity 0.810.09, near distance acuity 0.650.02. \u0000Conclusion. The IOL provides excellent visual acuity at far and middle distances, as well as functional visual acuity at near distance, which increases the independence from glasses. The target refraction was achieved in 91% of cases. The patients expressed high satisfaction with postoperative results. This lens can be recommended for use in clinical practice.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128698393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The epoxidation reaction in the analysis of terpenoids 萜类化合物分析中的环氧化反应
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-03-21 DOI: 10.55531/2072-2354.2023.23.1.25-30
A. M. Agafonov, I. Remezova, L. Anosova
{"title":"The epoxidation reaction in the analysis of terpenoids","authors":"A. M. Agafonov, I. Remezova, L. Anosova","doi":"10.55531/2072-2354.2023.23.1.25-30","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.1.25-30","url":null,"abstract":"Aim to determine the degree of unsaturation of some terpenoids and essential oils using peroxycarboxylic acids. \u0000Material and methods. The following terpenoids were used in the study: linalool, myrcene, lemon oil. The epoxidation reaction was carried out using pyroxydecanoic acid. The excess acid was measured by iodometric titration. \u0000Results. A method for determining the iodine number for essential oil was developed. Iodine numbers were calculated for some terpenoids (linalool, myrcene) and lemon oil. The reaction rate constants were calculated.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129026614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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