Experimental evaluation of the galvanophoretic dentin nanoimpregnation for recurrent caries prevention

A. R. Bessudnova, Vitalii A. Rumyantsev, Georgii A. Frolov, A. Blinova, Vladimir V. Bityukov
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Abstract

Aim to study the dentine galvanophoretic impregnation with nanoparticles of coppercalcium hydroxide (CCH) in the teeth with carious cavities. Material and methods. The study was conducted on 21 teeth removed for various medical indications, with a concomitant diagnosis "dental caries". After mechanical treatment, the cavities were washed with saline solution, then CCH paste was placed on the cavity floor, covered with aluminum foil, drained and isolated with temporary fillings. To maintain the osmotic balance, the teeth were placed in a laboratory model: a plastic bath with saline solution and a melamine sponge, for a period of 1, 14 and 30 days. Then the longitudinal teeth sections were prepared for the electron microscopic examination. Results. During the CCH galvanophoresis, the dentine impregnation with copper nanoparticles in the area of cavity floor occurred already during the first day of the procedure. The penetration depth reached 10.1 microns. The maximum depth of penetration of particles into the dentin (up to 30 microns) was detected after the 30-days-galvanophoresis. The maximum values of the diffusion coefficient and its velocity were recorded after the first day. With an increase in the time of galvanophoresis to 14 and 30 days, these indicators decreased. Conclusion. The described method may be used as an option of choice for the prevention of recurrent dental caries, especially in the presence of deep cavities.
电泳牙本质纳米浸渍预防复发性龋齿的实验评价
目的研究氢氧化铜纳米颗粒对龋牙本质电流电泳的浸渍作用。材料和方法。这项研究对21颗因各种医学指征而被拔掉的牙齿进行了研究,同时诊断为“龋齿”。机械处理后,用生理盐水冲洗龋洞,将CCH膏体放置于龋洞底,用铝箔覆盖,排干后用临时填充物隔离龋洞。为了保持渗透平衡,将牙齿放置在实验室模型中:用盐水溶液和三聚氰胺海绵进行塑料浴,为期1天,14天和30天。然后制备纵齿切片进行电镜检查。结果。在CCH电泳过程中,在手术的第一天,牙本质就已经被铜纳米颗粒浸没在腔底区域。穿透深度达到10.1微米。电泳30天后检测颗粒进入牙本质的最大深度(可达30微米)。扩散系数和扩散速度的最大值在第一天之后记录。随着电泳时间延长至14天和30天,这些指标有所下降。结论。所描述的方法可作为预防龋齿复发的一种选择,特别是在存在深腔的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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