Aspirantskiy Vestnik Povolzhiya最新文献

{"title":"Pre-treatment of granular osteoplastic material for improving the reparative regeneration of jaw bone defects","authors":"D. Malchikova","doi":"10.55531/2072-2354.2023.23.4.59-65","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.59-65","url":null,"abstract":"Aim – to develop a method for preliminary preparation of a granular osteoplastic material (GOM) for improving the quality of reparative osteogenesis of jaw bone defects that can be used in clinical setting. \u0000Material and methods. The in vitro study was performed using 9 samples (3 samples in each study group). Group 1 included intact samples of grafting material Cerabone (Botiss biomaterials GmbH, Germany). In group 2, the samples of Cerabone (Botiss biomaterials GmbH, Germany) were subject to degassing and dust extraction in two stages using the original method developed by the author. In group 3, a culture of mesenchymal-stromal cells (MSC) obtained from the human umbilical cord was used as a control. The developed method was assessed for cytotoxicity using human MSC. The proliferative index and cell doubling time were registered. A topographic analysis of the sample surface was performed using scanning electron microscopy. To assess the rate of degassing, the experiment included three replicates. The fluid volume was recorded every 2.5 minute. For statistical data processing, we used SPSS 25.0 software (IBM Corporation, Armonk, New York, USA). \u0000Results. In Group 2, that included the samples of GOM fractions with the preliminary degassing and dust extraction, we revealed a decreased content of coarse and fine fraction dust on the outer and inner surfaces of the pores and mouths of interpore channels and voids in all samples. The granular osteoplastic material prepared for the use by the method of degassing and dust extraction proved to have no toxic effect on the growth and viability of human mesenchymal-stromal cells. \u0000Conclusion. A preliminary preparation of GOM by the method of degassing and dust extraction developed by the author in clinical conditions ex tempore significantly optimizes the adsorption and drainage properties of the GOM fraction.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"3 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of permanent cardiac pacing modes in patients with arrhythmic variant of coronary artery disease (bradyarrhythmia)","authors":"M. D. Romanov, E. Kireeva, T. M. Levina, A. K. Bikmurzin","doi":"10.55531/2072-2354.2023.23.4.4-9","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.4-9","url":null,"abstract":"Aim – to analyze and compare the results of permanent cardiac pacing therapy in patients with arrhythmic variant of coronary artery disease (CAD) (grade II – III AV block and sinus node weakness syndrome). \u0000Material and methods. We studied the results of examination of 63 patients with arrhythmic variant of coronary artery disease (sinus node weakness syndrome and AV block), who received pacing therapy in VVI and DDD modes in the Department of Rhythm and Conduction Disorders of the Republican Clinical Hospital No. 4. All patients underwent clinical, laboratory and instrumental tests in accordance with federal clinical guidelines for CAD, rhythm and conduction disorders. \u0000Results. The left ventricular ejection fraction (LVEF) in patients with pacemakers in VVI mode was 9% lower when compared to LVEF in DDD mode. Mitral regurgitation was 47.6% more common in patients having VVI mode than DDD mode. In patients with the VVI regimen, the interventricular septal asynchrony was 25.1% more common and was accompanied by more pronounced left ventricle hypertrophy and dysfunction. Pacemaker syndrome was observed in 3 (7.5%) patients with VVI stimulation mode, stopped by reimplantation of a two-chamber frequency–adaptive pacemaker, and in 1 (4.35%) patient with DDD mode, eliminated by reprogramming. \u0000Conclusion. In patients with coronary artery disease, the effectiveness of pacing in correction of the cardiac rhythm and conduction depends on the treatment mode. Disorders of myocardial contractility are more pronounced in patients with VVI mode, if compared to DDD mode.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"5 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polysaccharide content and composition analysis in the herb Astragalus albicaulis DC","authors":"T. A. Pozdnуakova, R. Bubenchikov","doi":"10.55531/2072-2354.2023.23.4.72-76","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.72-76","url":null,"abstract":"Aim – to isolate and analyze the polysaccharides content in the herb Astragalus albicaulis. \u0000Material and methods. The object of the study was the herb Astragalus albicaulis harvested in the Kursk region in 2022 during the period of mass flowering. To isolate the polysaccharide complex, polyphenolic compounds were previously removed from the raw material. After drying, a water-soluble polysaccharide complex, pectin substances, hemicellulose A and hemicellulose B were sequentially isolated from the extraction cake. As extractants, purified water was used to isolate the water-soluble polysaccharide complex, a mixture of 0.5% solutions of oxalic acid and ammonium oxalate (1:1) was used for pectin substances extraction, to obtain hemicelluloses – a 10% aqueous solution of alkali followed by neutralization with acetic acid. The composition of the obtained substances was analyzed after acid hydrolysis using paper chromatography. \u0000Results. It was found that the yield of water-soluble polysaccharides from the herb Astragalus albicaulis was 9.41% ± 0.46%, pectin substances – 17.49% ± 0.62%, hemicellulose A – 0.86% ± 0.04%, hemicellulose B – 5.36% ± 0.25%. After acid hydrolysis, 5 monosaccharides were found in the complex of water-soluble polysaccharides: rhamnose, xylose, arabinose, galactose, and glucuronic acid, of which arabinose and galactose were predominant. The monosaccharide composition of pectin substances was represented by xylose, arabinose, glucose, galactose and galacturonic acid, galacturonic acid predominated. As a result of the identification of hydrolysis products of hemicellulose A and B, rhamnose, xylose and glucose were found, the predominant monosaccharide was xylose. \u0000Conclusion. For the first time, complexes of polysaccharides – water-soluble polysaccharides, pectin substances, hemicellulose A and B – were isolated and studied by fractions from the herb Astragalus albicaulis, their qualitative composition was registered. The data obtained indicates that the herb Astragalus albicaulis can be used as a source of natural polysaccharides.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suprachoroidal administration of triamcinolone acetonide in patients with macular edema after vitrectomy: Technique and results","authors":"A. Pershakova, I. S. Kazakov, M. A. Artemov, A. Zolotarev, O. V. Zhukova, E. Karlova, E. B. Eroshevskaya, V. M. Malov","doi":"10.55531/2072-2354.2023.23.4.44-50","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.44-50","url":null,"abstract":"Aim – to study the effectiveness of triamcinolone acetonide (TA) injection into the suprachoroidal space using a microneedle for the treatment of macular edema after vitrectomy. \u0000Material and methods. During the study, the results of suprachoroidal administration of triamcinolone acetonide were analyzed in 8 patients (8 eyes) who were observed with macular edema as a complication of vitrectomy. Ophthalmological examination included visometry, non-contact tonometry, indirect ophthalmoscopy with lens 78 D, and optical coherence tomography (OCT) of the macular area. Best corrected visual acuity (BCVA) before the operation ranged from 0.1 to 0.8 (0.25 (0.10; 0.50), retinal thickness in the foveolar area varied from 342 to 728 µm (513.0 (443.0; 585.5) according to OCT data. During the operation, all patients underwent the injection of 0.1 ml of triamcinolone acetonide using a microneedle into the suprachoroidal space 3.5-4.0 mm posterior to the limbus. \u0000Results. One month after suprachoroidal injection of TA, the thickness of macular edema statistically significantly decreased to 327.5 (309.0; 380.5) μm (p = 0.011719) and BCVA increased to 0.45 (0.25; 0.80) (p = 0.027709). Three months after surgery, the retinal thickness in the macular area was 333.5 (311.5; 503.0) (p = 0.068704). The lack of statistical significance in the reduction of macular edema 3 months after suprachoroidal TA injection is explained by the fact that 3 out of 8 patients (37.5%) experienced a recurrence of macular edema after 3 months. However, BCVA has significantly increased to 0.6 (0.25; 0.90) (p = 0.043115). In 5 out of 8 patients (62.5%) a stable positive result was achieved within 3 months in the form of relief of macular edema. In the postoperative period, an increase in intraocular pressure was noted only in 2 cases of measurements, in patients observed for secondary glaucoma as a concomitant diagnosis. Intraocular pressure was compensated in both cases after correction of the treatment regimen. \u0000Conclusion. The presented technique is effective in treatment of macular edema associated with vitrectomy, as well as safe, which may be the reason for its further study.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer accomodography data for assessing tolerability of optical correction for myopia in near work","authors":"M. Abida, O. V. Zhukova, A. E. Sineok, V. M. Malov, E. B. Eroshevskaya","doi":"10.55531/2072-2354.2023.23.4.10-14","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.10-14","url":null,"abstract":"Aim – to study the results of computer accomodography in children with myopia optical correction in order to assess the optical correction tolerability during visual work at close distance. \u0000Material and methods. The study of myopia optical correction tolerance in near work included 45 children of school age. Subjective and objective research methods were used: a relative accommodation reserve study and computer accomodography. \u0000Results. The computer accomodography performed with glasses allowed to determine the nature of the ciliary muscle work in near vision. Computer accomodography data correlated with the value of relative accommodation reserve. \u0000Conclusion. We recommend to study the relative accommodation reserve and to use computer accomodography when choosing the optical correction for myopic children.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methods of intraocular lens fixation in complicated cases of lens surgery","authors":"F. Ben Amor, A. E. Sineok, O. V. Zhukova, V. M. Malov, E. B. Eroshevskaya","doi":"10.55531/2072-2354.2023.23.4.20-26","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.20-26","url":null,"abstract":"There is a growing attention to the lens surgery in complicated cases that require to obtain a good functional result and to minimize the surgical volume. The intraocular lens fixation remains a major problem in complicated cases in lens surgery due to the inadequate capsular support. It is essential to achieve the refractive goal and correct positioning of the intraocular lens both immediately after operation and in the long-term period. \u0000The article reviews current available scientific literature of domestic and international authors devoted to the problem of intraocular lens fixation in complicated cases of lens surgery.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"14 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reposition of dislocated piggyback intraocular lens in a patient with induced keratectasia after radial keratotomy","authors":"M. A. Artemov, I. S. Kazakov, V. M. Malov, A. Zolotarev, E. B. Eroshevskaya, E. Karlova","doi":"10.55531/2072-2354.2023.23.4.15-19","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.15-19","url":null,"abstract":"Aim – to substantiate low-traumatic sutureless surgery for piggyback intraocular lens (IOL) reposition as a method of choice in a patient after previous keratorefractive surgery and cataract phacoemulsification. \u0000The article provides the examination and surgical treatment data of one patient with piggyback intraocular lens dislocation after previous radial keratotomy and keratectasia. \u0000The presented clinical case shows that proper consideration of eye anatomical features allows for effective low-traumatic sutureless piggyback IOL reposition in patients who have previously undergone radial keratotomy, and may lead to sustainable high visual and functional results.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for the development of temporomandibular joint dysfunction","authors":"Tatyana A. Olshanskaya, Valerii V. Konnov","doi":"10.55531/2072-2354.2023.23.2.19-26","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.19-26","url":null,"abstract":"The temporomandibular joint dysfunction (TMD) is a fairly common pathology among dental diseases. In this regard, in addition to the most common causes of the development of this pathology, it is worth paying attention to the provoking factors that contribute to the formation of dysfunction of the temporomandibular joint. \u0000The review examines the current available literary data of domestic and foreign authors on the etiology of TMD.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"181 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131558459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia in elderly patients with type 2 diabetes: risk factors","authors":"","doi":"10.55531/2072-2354.2023.23.2.66-73","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.66-73","url":null,"abstract":"Aim to determine the risk factors for sarcopenia in elderly patients with type 2 diabetes (T2DM). \u0000Material and methods. The study included 395 elderly patients with T2DM (mean age 65.1 2.7 years). The probable sarcopenia group (n = 185) included participants with low muscle strength, the control group (n = 210) included participants without sarcopenia. In all participants we registered the anthropometric indicators; fasting blood glucose; glycated hemoglobin (HbA1c); albumen; creatinine; body composition; handgrip strength. The food diary was used to calculate total daily calories, the amount of carbohydrates, proteins and fats eaten per day, as well as the proportion of calories provided by these macronutrients. \u0000Results. Compared with the controls, the male and female patients with probable sarcopenia were older (p0.001) and had lower waist-to-hip ratio (p=0.038 and p=0.018, respectively) and BMI (p=0.001 and p0.001 respectively), eGFR (p=0.030 and p=0.018, respectively), bone mineral content (p0.001), basal metabolic rate (p=0.016 and p0.001, respectively), appendicular skeletal muscle mass (p=0.043 and p0.001, respectively), appendicular musculoskeletal mass index (p=0.002 and p0.001, respectively) and muscle quality (p0.001), high fasting plasma glucose (p=0.017 and p=0.007, respectively) and HbA1c (p0.001 and p=0.004, respectively). In men with probable sarcopenia, the percentage of calories provided by carbohydrates was lower (p=0.041), while the percentage provided by fats (p= 0.012) was higher than in the control group. \u0000Conclusion. The multivariate logistic regression analysis showed that age (OR = 1.517, 95% CI: 1.127-2.043, p=0.006), male sex (OR = 0.196, 95% CI: 0.142-0.271, p0.001), BMI 28 kg/m2 (OR = 0.683, 95% CI: 0.467-0.998, p=0.049), HbA1c level 10% (OR = 1.396, 95% CI: 1.018-1.915, p=0.038), diabetic nephropathy (OR = 1.439, 95% CI: 1.033-2.006, p=0.031) and decreased serum albumin (OR = 0.917, 95% CI: 0.883-0.953, p0.001) were risk factors associated with low muscle strength in patients with type 2 diabetes type.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"252 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134191433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The occurrence of allergic diseases in children with normal weight, excess body weight and obesity: a comparative analysis","authors":"O. Skvortsova, N. Migacheva, Evgeniya G. Mikhaylova","doi":"10.55531/2072-2354.2023.23.2.74-80","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.2.74-80","url":null,"abstract":"Aim to study the prevalence of allergic diseases (AD), excess body weight and obesity in school children and to analyze the correlations between the AD diagnosis and body weight. \u0000Material and methods. During the single-stage observational study, 1503 children aged from 7 to 14 years received medical checkup. In all children, we measured anthropometric data, calculated body mass index and standard sigma deviation with the following assessment. The information about the presence of AD was obtained from the primary medical documentation of schoolchildren. Then, we conducted a telephone survey of the parents of the examined children to clarify the data on the presence of allergopathology in them. \u0000Results. The prevalence of excess body weight in school-children was 20.9%, obesity 13.5%. The prevalence of atopic dermatitis (AtD) according to the medical record was 6.72%, allergic rhinitis (AR) 6.65%, bronchial asthma (BA) 1.86%. The statistical analysis of mentioned diseases revealed no correlation between the increased body weight and the prevalence of AD both in the general cohort of children, and when stratified by age and gender. The comparative analysis of the telephone survey data on the prevalence of allergopathology in overweight and obese children provided statistically significant results: with the weight gain, the prevalence of the studied allergic diseases was increasing. \u0000Conclusion. The results of the study did not reveal a statistically significant positive association between excess body weight, obesity and the presence of AD in the children of the examined group. However, the differences in the prevalence of allergopathology in schoolchildren according to primary medical documentation and the results of a telephone survey of parents indicate the need for a deeper study of the problem and an epidemiological study of the true prevalence of AD in children, followed by an analysis of the association between these conditions.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129890359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}