Aspirantskiy Vestnik Povolzhiya最新文献

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DENTAL STATUS OF PATIENTS WITH NEW CORONAVIRUS INFECTION COVID-19. 新型冠状病毒感染科维德-19 患者的牙齿状况。
Aspirantskiy Vestnik Povolzhiya Pub Date : 2024-03-23 DOI: 10.35693/avp562724
Madina Dzgoeva
{"title":"DENTAL STATUS OF PATIENTS WITH NEW CORONAVIRUS INFECTION COVID-19.","authors":"Madina Dzgoeva","doi":"10.35693/avp562724","DOIUrl":"https://doi.org/10.35693/avp562724","url":null,"abstract":"The aim of the investigation was to clarify the features of the clinical symptoms of patients with the new coronavirus infection COVID-19. \u0000Material and methods: A total of 156 patients undergoing treatment in COVID-hospitals were examined. The examination included the determination of the prevalence of: COVID 19 clinical symptoms, COVID 19 clinical manifestations in the oral cavity, concomitant diseases. \u0000Results. In the structure of general symptoms, complaints of hyperthermia, general weakness and cough (more often dry) played a leading role, which were noted by the overwhelming majority of the examined. Two-thirds of the patients reported body pain. The leading symptoms were also anosmia (in 68.6% of cases) and sweating (64.1%).More than half of the patients complained of shortness of breath (60.2%), difficulty in nasal breathing (55.1%), a feeling of tickling (58.3%) and pain (60.2%) in the throat. Among dental pathology, loss of taste (57.5%) and hyposalivation (38.5%) were the most common in patients. Bleeding gums were detected in 22.4% of the examined patients, which is most likely due to violations of the rheological properties of blood and changes in the hemodynamic provision of the periodontal during Covid19. Clinical manifestations of periodontal pathology do not occur immediately, but in the form of long-term complications. In this regard, it seems necessary to dynamically monitor the condition of patients who have undergone COVID-19 in different time periods. \u0000Conclusions. Hemostasis disorders characteristic of the new COVID-19 coronavirus infection certainly have an impact on the state of dental status, further destroying periodontal tissues. However, clinical manifestations of pathological effects may not occur immediately, but in the form of long-term complications. In this regard, it is necessary to dynamically monitor the condition of patients who have undergone COVID-19 in different time periods.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":" 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140211305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CHARACTERISTICS OF PERIPHERAL BLOOD INDICATORS AND IMMUNE STATUS IN PATIENTS WITH COINFECTED INFLUENZA AND COVID-19 合并感染流感和 Covid-19 患者的外周血指标特征和免疫状态
Aspirantskiy Vestnik Povolzhiya Pub Date : 2024-03-22 DOI: 10.35693/avp602350
Yana Alexandovna Safronova, Alexander Sergeevich Pankov
{"title":"CHARACTERISTICS OF PERIPHERAL BLOOD INDICATORS AND IMMUNE STATUS IN PATIENTS WITH COINFECTED INFLUENZA AND COVID-19","authors":"Yana Alexandovna Safronova, Alexander Sergeevich Pankov","doi":"10.35693/avp602350","DOIUrl":"https://doi.org/10.35693/avp602350","url":null,"abstract":"The new coronavirus infection has played a significant role in the structure of acute respiratory diseases [1,2], and in combination with influenza, it changes not only the clinical picture, but also changes the laboratory parameters of the disease, primarily indicators of peripheral blood and immune status. The paper presents the features of the clinical course of coinfection, as well as the results of the parameters of the immune status. Based on the data obtained, the risk of developing fibrosis in infected patients was assessed in comparison with control groups.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140216062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features of coronavirus infection with impaired sense of smell 冠状病毒感染导致嗅觉受损的临床特征
Aspirantskiy Vestnik Povolzhiya Pub Date : 2024-03-22 DOI: 10.35693/avp627315
A. V. Lukyanov, A. A. Ploskireva
{"title":"Clinical features of coronavirus infection with impaired sense of smell","authors":"A. V. Lukyanov, A. A. Ploskireva","doi":"10.35693/avp627315","DOIUrl":"https://doi.org/10.35693/avp627315","url":null,"abstract":"Previously, olfactory disturbances were not considered as a possible single symptom of an acute period of coronavirus infection. \u0000Aim: to identify the clinical features of low-symptomatic forms of COVID-19 coronavirus infection occurring with olfactory dysfunction. \u0000Materials and methods: the study was conducted on the basis of the Federal State Budgetary Institution of the Central Research Institute of Epidemiology of Rospotrebnadzor by questioning people who have suffered a coronavirus infection. A total of 39,676 people were interviewed, of whom 24,086 (60.70%) had suffered some form of new coronavirus infection COVID-19. Methods of descriptive statistics were used for statistical analysis of the research results. \u0000Results: olfactory dysfunction may be the only symptom of the acute period of COVID-19 coronavirus infection in 4%. The occurrence of this symptom depends on the dominant circulating genovariant (maximum at Alpha is 7.8%), the basic reproductive number (inverse relationship, Pearson correlation coefficient -0.9) and the age of the patient (more often in persons under 44 years of age). The occurrence of the symptom does not depend on the patient's gender. Patients with olfactory dysfunction with COVID-19 coronavirus infection are significantly less likely (4.2% vs. 12.6%, P = 0.04) to require hospitalization and oxygen therapy (2.5% vs. 32.2%, P 0.001). \u0000Conclusion: olfactory dysfunction may be the only symptom of the acute period of COVID-19 coronavirus infection, which allows us to suggest its isolation into a separate form. The occurrence of this form depends on the dominant circulating genovariant, the basic reproductive number of the virus and the age of the patient. Patients with this form of coronavirus infection are less likely to require hospitalization and oxygen therapy.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":" 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140211331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MICROSCOPIC EXAMINATION OF THE CEPHALARIA GIGANTEA (LEDEB.) BOBROV 显微镜下观察头状花序(ledeb.
Aspirantskiy Vestnik Povolzhiya Pub Date : 2024-03-22 DOI: 10.35693/avp121342
O. A. Kalashnikova, V. A. Kurkin, Vitaliy Mirhaylovich Ryzhov, L. Tarasenko, Anastasia Alexeyevna Ushkova, Irina Vasilevna Ruzaeva
{"title":"MICROSCOPIC EXAMINATION OF THE CEPHALARIA GIGANTEA (LEDEB.) BOBROV","authors":"O. A. Kalashnikova, V. A. Kurkin, Vitaliy Mirhaylovich Ryzhov, L. Tarasenko, Anastasia Alexeyevna Ushkova, Irina Vasilevna Ruzaeva","doi":"10.35693/avp121342","DOIUrl":"https://doi.org/10.35693/avp121342","url":null,"abstract":"Giant cephalaria [Cephalaria gigantea (Ledeb.) Bobrov] is a promising source of biologically active compounds. The analysis of the scientific periodical literature shows a high interest in the aboveground part of this plant species. To give the Cephalaria gigantea herbs pharmacopoeia status, it is necessary to solve a number of issues, in particular, the development of regulatory documentation for the standardization of new medicinal plant raw materials. One of the important aspects of standardization of medicinal plant raw materials is the issue of confirming its authenticity by morphological and anatomical analysis. The literature data indicate, that the anatomical and histological features of the structure of the Cephalaria gigantea herbs have not been sufficiently studied. This article presents the results of a morphological and anatomical study of the aboveground part of the Cephalaria gigantea.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140216925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological modulation of wound healing in glaucoma surgery 青光眼手术中伤口愈合的药理调节
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.51-58
M. V. Radaykina, A. Zolotarev, E. Karlova, V. M. Malov, E. B. Eroshevskaya
{"title":"Pharmacological modulation of wound healing in glaucoma surgery","authors":"M. V. Radaykina, A. Zolotarev, E. Karlova, V. M. Malov, E. B. Eroshevskaya","doi":"10.55531/2072-2354.2023.23.4.51-58","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.51-58","url":null,"abstract":"Excessive scarring in the area of hypotensive glaucoma surgery is still a challenge in ophthalmology as it is the main cause of postoperative IOP elevation. The antiproliferative pharmacologic agents currently used for wound healing modulation are either not effective enough or have poor safety profile. \u0000The review provides a brief description of wound healing physiology including cytokines involved in it. It also represents the mechanisms of action and effects of drugs that influence wound healing and are used as antiproliferative agents for prevention of excessive scarring in glaucoma surgery.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138586075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes of surgical treatment for cataract and asteroid hyalosis 白内障和小行星透明症手术治疗的长期效果
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.32-37
A. M. Danilov, A. G. Grinev, E. B. Eroshevskaya
{"title":"Long-term outcomes of surgical treatment for cataract and asteroid hyalosis","authors":"A. M. Danilov, A. G. Grinev, E. B. Eroshevskaya","doi":"10.55531/2072-2354.2023.23.4.32-37","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.32-37","url":null,"abstract":"Aim – to assess long-term surgical treatment outcomes and subjective level of satisfaction in patients with cataract and asteroid hyalosis. \u0000Material and methods. The study involved 120 patients (120 eyes) diagnosed with cataract and asteroid hyalosis. During the study, the patients were randomly assigned into 3 equivalent groups of 40 people each, depending on the surgical treatment method. Group I was formed of patients after phacovitrectomy through posterior capsulorhexis, group II included patients after total three-port phacovitrectomy, group III - patients after cataract phacoemulsification. Before the surgery, on the day of discharge, 1, 3 and 6 months after the operation, all patients received standard ophthalmological check-up and answered validated visual function questionnaire \"The Visual Function test\" (VF-14) assessing their subjective perception of life quality. \u0000Results. Visual acuity was comparable in all groups up to 1-3 months after surgery. The subjective level of satisfaction was significantly higher in patients after phacovitrectomy (groups I and II), regardless of the time passed after the operation. Some patients of group III applied for surgical treatment again due to unsatisfactory results of the previous operation. \u0000Conclusion. In patients with cataract with underlying vitreous destruction in the form of asteroid hyalosis, it is recommended to perform phacovitrectomy in order to achieve high functional result, as well as to improve the patient's subjective feeling of the life quality.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical issues of toxic goiter diagnosis and treatment 诊断和治疗毒性甲状腺肿的热点问题
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.77-86
I. V. Makarov, R. Galkin, A. S. Shpigel, E. Lebedeva, S. Bulgakova, R. M. Romanov, V. N. Kudashkin
{"title":"Topical issues of toxic goiter diagnosis and treatment","authors":"I. V. Makarov, R. Galkin, A. S. Shpigel, E. Lebedeva, S. Bulgakova, R. M. Romanov, V. N. Kudashkin","doi":"10.55531/2072-2354.2023.23.4.77-86","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.77-86","url":null,"abstract":"Among the causes of thyrotoxicosis, the diffuse toxic goiter is found in 75-80% of cases, the toxic multinodular goiter is observed in 20-25% of cases. The article presents the data on various aspects of surgical treatment of thyroid diseases found in international databases.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative phytochemical study of white poplar (Populus alba L.) and black poplar (Populus nigra L.) 白杨和黑杨的植物化学比较研究
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.66-71
A. Kosenko, A. Kurkina
{"title":"Comparative phytochemical study of white poplar (Populus alba L.) and black poplar (Populus nigra L.)","authors":"A. Kosenko, A. Kurkina","doi":"10.55531/2072-2354.2023.23.4.66-71","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.66-71","url":null,"abstract":"Aim – to conduct a comparative phytochemical study of leaves, wood buds, shoots, bark of two representatives of the genus poplar – white poplar and black poplar. \u0000Material and methods. For the experiment, we have chosen leaves, wood shoots, buds, bark of black poplar (Populus nigra L.), white poplar (Populus alba L.) and also reference standards (RS). The thin-layer chromatography was carried out on the plates Sorbfil-PTSH-AF-A-UV in the systems n-butanol-acetic acid-water (4:1:2) and chloroform-ethyl alcohol-water (25:18:2). The spectrophotometry was carried out on a Specord 40 spectrophotometer (Analytik Jena) in cuvettes with a layer thickness of 10 mm in the wavelength range from 190 to 500 nm. The comparison solution was ethyl alcohol of 96% concentration. \u0000Results. In the water-alcohol extracts of the leaves of poplar species the presence of rutin and other phenolic compounds was detected. Pinostrobin and pinocembrin were observed in wood shoots, buds and bark of the plants. The bathochromic shift of the long-wavelength line in the ultraviolet spectra of the studied extracts solutions indicated the presence of flavonoids. \u0000Conclusion. In all cases, flavonoids made the greatest contribution to the absorption curves of the spectra, in particular: flavanones (pinocembrine, pinostrobin, and others), and phenylpropanoids (caffeic acid and other cinnamic acids). The leaves, wood shoots and buds of the plants contained substances of a phenolic nature, including flavonoids. The composition of the bark of the white poplar was mainly represented by phenolic compounds – phenylpropanoids and simple phenols.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"7 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Origin of stage I-II retinopathy I-II 期视网膜病变的起源
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.38-43
A. Y. Lazutkina
{"title":"Origin of stage I-II retinopathy","authors":"A. Y. Lazutkina","doi":"10.55531/2072-2354.2023.23.4.38-43","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.38-43","url":null,"abstract":"Aim – to study the causes of retinopathy (RP) formation and progression at the initial stages. \u0000Material and methods. The data of a 6-year prospective follow-up of a natural group of initially healthy male workers aged 18-66 years (n = 7,959) were used to determine the predictors of stage I-II RP. For this purpose, a 2×2 confusion matrix and a multivariate regression model were used, and the relative risk factors were assessed. \u0000Results. Stage I-II retinopathy was caused by such factors as age from 26 to 66 years, arterial hypertension, smoking, dyslipidemia, hyperglycemia, family history of early cardiovascular diseases, degree I-III obesity, left ventricular myocardial hypertrophy, microalbuminuria, type 2 diabetes mellitus, creatininemia, atherosclerotic plaque / thickening of the intima-media complex, aortic atherosclerosis. All predictors except for smoking, degree I-III obesity and aortic atherosclerosis had a statistically significant result in the applied mathematical models. \u0000Conclusion. Statistical heterogeneity of the stage I-II RP predictors is likely to be related to the qualitative specific characteristics of RP predictors and their unique damage effect in the development of stage I-II RP.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micropulse cyclophoto-coagulation in patients with primary open-angle glaucoma: early results 原发性开角型青光眼患者的微脉冲环形光凝疗法:早期结果
Aspirantskiy Vestnik Povolzhiya Pub Date : 2023-12-09 DOI: 10.55531/2072-2354.2023.23.4.27-31
V. N. Germanova, A. V. Sorokin, A. Zolotarev, E. Karlova, V. M. Malov, M. V. Radaykina, O. V. Zhukova
{"title":"Micropulse cyclophoto-coagulation in patients with primary open-angle glaucoma: early results","authors":"V. N. Germanova, A. V. Sorokin, A. Zolotarev, E. Karlova, V. M. Malov, M. V. Radaykina, O. V. Zhukova","doi":"10.55531/2072-2354.2023.23.4.27-31","DOIUrl":"https://doi.org/10.55531/2072-2354.2023.23.4.27-31","url":null,"abstract":"Aim – to evaluate the efficacy and safety of micropulse transscleral cyclophotocoagulation (MP-TSCPC) procedure in patients with primary open-angle glaucoma (POAG). \u0000Material and methods. The study was conducted in 21 patients with POAG and uncompensated intraocular pressure (IOP) using pharmacotherapy. All patients underwent MP-TSCPC procedure with IRIDEX Cyclo G6 device. The follow-up period lasted for 1 month. During this time, the visual acuity, IOP dynamics, complications, as well as the number of hypotensive drugs used were evaluated. Statistical analysis was performed using STATISTICA 12.0 software. \u0000Results. Among patients with moderate and advanced glaucoma, the IOP reduced by 46.7 (3.3; 64.3) % from baseline values by the end of the follow-up period. The target IOP was achieved in 30.7% of patients. In 75% of patients who achieved target IOP, the number of hypotensive drops used was reduced by 1 component. In all patients with terminal stage glaucoma, pain was relieved, and IOP was reduced by 35.5 (8.4; 41.1) %. No intra- or postoperative complications were reported in any case. \u0000Conclusion. MP-TSCPC can be considered as a relatively safe adjunctive method to achieve target IOP in addition to medical treatment in patients with moderate and advanced glaucoma, as well as appropriate method to control pain in patients with the terminal stage of the disease.","PeriodicalId":183034,"journal":{"name":"Aspirantskiy Vestnik Povolzhiya","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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