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[Intestinal gluconeogenesis : When the intestine produces glucose to prevent obesity and hepatic steatosis]. [肠道糖异生：肠道产生葡萄糖以防止肥胖和肝脂肪变性]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025023
Justine Vily-Petit, Amandine Gautier-Stein, Gilles Mithieux
{"title":"[Intestinal gluconeogenesis : When the intestine produces glucose to prevent obesity and hepatic steatosis].","authors":"Justine Vily-Petit, Amandine Gautier-Stein, Gilles Mithieux","doi":"10.1051/medsci/2025023","DOIUrl":"10.1051/medsci/2025023","url":null,"abstract":"<p><p>Intestinal gluconeogenesis refers to the ability of the gut to produce glucose outside of meals. By initiating a gut-brain neural axis, its activation by dietary fiber or protein improves the regulation of energy balance. Recently, the creation of a genetic activation model of intestinal gluconeogenesis has demonstrated its anti-obesity, anti-diabetes and anti-hepatic steatosis effects. Interestingly, it increases thermogenesis in brown adipose tissue, thereby promoting energy expenditure and contributing to the fight against obesity. Therefore, targeting intestinal gluconeogenesis could be an innovative strategy to address metabolic diseases such as hepatic steatosis and diabetes, paving the way to new therapeutic approaches.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"246-252"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Aerenchyma and the overlooked gas transfers in plants]. [灌浆和植物中被忽视的气体转移]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025039
Marc-André Selosse
{"title":"[Aerenchyma and the overlooked gas transfers in plants].","authors":"Marc-André Selosse","doi":"10.1051/medsci/2025039","DOIUrl":"https://doi.org/10.1051/medsci/2025039","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"286-289"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rejuvenation of CD8+ T cell responses in long-term treated people with HIV]. [长期接受治疗的艾滋病毒感染者 CD8+ T 细胞反应的年轻化]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025031
Eoghann White, Victor Appay
{"title":"[Rejuvenation of CD8<sup>+</sup> T cell responses in long-term treated people with HIV].","authors":"Eoghann White, Victor Appay","doi":"10.1051/medsci/2025031","DOIUrl":"https://doi.org/10.1051/medsci/2025031","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"229-232"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Optogenetics contributes to the study of biophysical phenomena during inflammasome-induced pyroptosis]. [光遗传学有助于研究炎症小体诱导的焦亡过程中的生物物理现象]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025033
Khalil Hodroj, Hubert Leloup, Virginie Petrilli
{"title":"[Optogenetics contributes to the study of biophysical phenomena during inflammasome-induced pyroptosis].","authors":"Khalil Hodroj, Hubert Leloup, Virginie Petrilli","doi":"10.1051/medsci/2025033","DOIUrl":"https://doi.org/10.1051/medsci/2025033","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"235-238"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Autophagy, dendritic cells, and Crohn's disease - "There is no point in running ; we must leave at the right time"]. [自噬、树突状细胞和克罗恩病--"逃避毫无意义；我们必须适时离开"]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025027
Leslie Andromaque, Stéphane Nancey, Mathias Faure, Aurore Rozières
{"title":"[Autophagy, dendritic cells, and Crohn's disease - \"There is no point in running ; we must leave at the right time\"].","authors":"Leslie Andromaque, Stéphane Nancey, Mathias Faure, Aurore Rozières","doi":"10.1051/medsci/2025027","DOIUrl":"https://doi.org/10.1051/medsci/2025027","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"216-219"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Life is shaped by differences not supporting any hierarchy]. [生活是由差异决定的，而不是由等级制度决定的]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025038
Jean-Christophe Pagès
{"title":"[Life is shaped by differences not supporting any hierarchy].","authors":"Jean-Christophe Pagès","doi":"10.1051/medsci/2025038","DOIUrl":"https://doi.org/10.1051/medsci/2025038","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"282-285"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[EU-JAMRAI - Europe committed to a coordinated response and a "one health" approach to tackle antibiotic resistance]. [EU-JAMRAI -欧洲承诺采取协调一致的应对措施和“同一个健康”方法来解决抗生素耐药性问题]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025040
Yohann Lacotte, Evelyne Jouvin-Marche, Marie-Cécile Ploy
{"title":"[EU-JAMRAI - Europe committed to a coordinated response and a \"one health\" approach to tackle antibiotic resistance].","authors":"Yohann Lacotte, Evelyne Jouvin-Marche, Marie-Cécile Ploy","doi":"10.1051/medsci/2025040","DOIUrl":"https://doi.org/10.1051/medsci/2025040","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"211-212"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Glucocorticoid-related cell stimulation : A causal factor of therapeutic resistance in childhood leukemia]. [糖皮质激素相关细胞刺激：儿童白血病治疗耐药的一个原因]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025030
Souleymane Abdoul-Azize
{"title":"[Glucocorticoid-related cell stimulation : A causal factor of therapeutic resistance in childhood leukemia].","authors":"Souleymane Abdoul-Azize","doi":"10.1051/medsci/2025030","DOIUrl":"https://doi.org/10.1051/medsci/2025030","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"226-228"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dengue treatments and vaccines]. [登革热治疗和疫苗]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-03-01 Epub Date: 2025-03-21 DOI: 10.1051/medsci/2025025
Lazare Brézillon-Dubus, Benjamin Dupuis, Anna-Bella Failloux
{"title":"[Dengue treatments and vaccines].","authors":"Lazare Brézillon-Dubus, Benjamin Dupuis, Anna-Bella Failloux","doi":"10.1051/medsci/2025025","DOIUrl":"10.1051/medsci/2025025","url":null,"abstract":"<p><p>Dengue fever is a viral disease transmitted by mosquitoes of the Aedes genus, whose incidence and range have been steadily increasing in recent decades. Causing hemorrhagic fever in severe cases, it affects the inter-tropical regions of the world and threatens to spread to new geographical areas. Its complex pathophysiology and the existence of four genetically distant serotypes make vaccine development a challenge. Currently, there is no specific treatment against dengue fever and only a few vaccines are marketed or in development, with some limitations on their use. It is therefore necessary to develop new vaccines and identify new molecules with antiviral properties to reduce the economic and public health burden of this disease in endemic areas.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 3","pages":"260-272"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Development of a nanoprobe carried by E. coli that can be triggered in situ to diagnose and treat tumours]. [一种由大肠杆菌携带的纳米探针的开发，它可以被原位触发来诊断和治疗肿瘤]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-02-01 Epub Date: 2025-03-03 DOI: 10.1051/medsci/2025021
Nolwenn Roger, Léa Moutardier
{"title":"[Development of a nanoprobe carried by E. coli that can be triggered in situ to diagnose and treat tumours].","authors":"Nolwenn Roger, Léa Moutardier","doi":"10.1051/medsci/2025021","DOIUrl":"https://doi.org/10.1051/medsci/2025021","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 2","pages":"201-202"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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